Clinical trials: End-stage Kidney Disease
Chronic Kidney Failure
Exercise for Chronic Kidney Diseases
PURPOSE: To compare between the effect of aerobic exercise and resistance exercises on patients with obese chronic kidney diseases.
- Trial name
- NCT04522115
- Testing
- exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
End Stage Renal Failure on Dialysis, Arteriovenous Graft Occlusion
Sirolimus Coated Angioplasty Balloon in the Salvage of Thrombosed Arteriovenous Graft
End stage renal disease is on increasing trend. Haemodialysis is the main dialysis modality among these patients which accounts for the incidence of 81.3% in 2015 based on data from Singapore renal registry.
- Trial name
- NCT03666208
- Testing
- Sirolimus Coated Balloon
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Singapore General Hospital
End Stage Renal Disease
Effect of Hemodialysis on Toe Pressure- and Finger Pressure and Skin Autofluorescence in Hemodialysis Patients
The aim of this study is to determine the vascular condition of hemodialysis patients with toe pressure measurement, finger pressure measurement and measuring glycated and oxidated proteins by skin autofluorescence.
- Trial name
- NCT00431314
- Volunteers
- 82 people
- Sponsor
- Isala
End-Stage Renal Disease, Kidney Failure
Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation
In a non-blinded pilot study conducted at the University of Nebraska Medical Center, evidence was found that a single large dose of Thymoglobulin on the day of kidney transplantation produced better kidney function than the…
- Trial name
- STAT (NCT00906204)
- Testing
- Single-dose rabbit Anti-thymocyte Globulin induction, Divided-dose rabbit Anti-thymocyte Globulin induction
- Where
- 4 sites in United States
- Volunteers
- 99 people
- Sponsor
- Wright State University
Diabetic Kidney Disease (DKD)
YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study1
In order to reduce the clinical demand for kidney dialysis rate of Diabetic Kidney Disease（DKD） patients, a bidirectional cohort study of 4472 patients with DKD (Qi deficiency and collateral stasis syndrome) was carried out based…
- Trial name
- NCT07032116
- Where
- 5 sites in China
- Volunteers
- 4,472 people
- Sponsor
- Liu Hongfang
End Stage Renal Disease
Examining the Impact of Using Two Dialysers in Parallel on Dialysis Adequacy in Hemodialysis Patients
The purpose of this study is to investigate the effectiveness of using two dialysers to lower the blood mineral levels in people receiving hemodialysis as compared to using one dialyser (usual treatment).
- Trial name
- NCT01539252
- Testing
- Single dialyzer, Two dialyzers
- Where
- 2 sites in Canada
- Volunteers
- 33 people
- Sponsor
- University of Alberta
End Stage Renal Disease
Less Frequency Hemodialysis and COVID-19
Facing the unusual situation imposed by the coronavirus disease, the aim of this study is to evaluate the risk and effects of less frequent hemodialysis on prevalent patients
- Trial name
- NCT04374058
- Testing
- less-frequency hemodialysis
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- Dialisis Madariaga
End Stage Renal Disease on Dialysis
MoVE Trial: Motivational Strategies to Empower African Americans to Improve Dialysis Adherence
MoVE Trial is a randomized clinical trial designed to rigorously test the impact of a behavioral intervention (culturally tailored motivational interviewing - (MOVE)) delivered by trained health coaches, on hemodialysis treatment…
- Trial name
- NCT05735743
- Testing
- Motivational interviewing
- Where
- 6 sites in United States
- Volunteers
- 176 people
- Sponsor
- Vanderbilt University Medical Center
End-Stage Renal Disease, Osteoporosis
Can Alendronate Suppress Calcification and Improve Bone Density in Chronic Peritoneal Dialysis Patients?
Alendronate is a safe and effective drug for treating osteoporosis in post-menopausal women. However, its safety and efficacy in increasing bone mineral density in chronic peritoneal dialysis (PD) patients have not been…
- Trial name
- NCT00261625
- Testing
- alendronate
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Cancer, End Stage Renal Disease
The Singapore Chinese Health Study
The "Singapore Chinese Health Study" is a cohort study established by the Department of Epidemiology and Public Health in National University of Singapore, together with collaborators from several universities in the United…
- Conditions
- Cancer, End Stage Renal Disease, Diabetes, Cardiovascular Diseases
- Trial name
- SCHS (NCT03356340)
- Volunteers
- 63,257 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Infraclavicular Brachial Plexus Block
2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula
Will the technique of adding lidocaine to bupivacaine fasten the onset of bupivacaine alone for infraclavicular brachial plexus block in end-stage renal disease (ESRD) patient?
- Trial name
- NCT00993746
- Testing
- Bupivacaine plus lidocaine, Bupivacaine 30 ml
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Diabetes, Chronic Kidney Disease
Glycaemic Response to Oral Nutrition Support During Haemodialysis
Patients with kidney, or renal, failure require life-saving treatment with regular dialysis. Dialysis is a form of treatment that simulates some kidney functions; to remove harmful waste products and extra water from the blood.
- Conditions
- Diabetes, Chronic Kidney Disease, End Stage Renal Failure on Dialysis
- Trial name
- GRO-HD (NCT02989688)
- Testing
- Nepro HP (Abbott Nutrition), Fortisip compact protein 125 ml + Calogen 20ml (Nutricia), Fortisip compact 125 ml (Nutricia)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- King's College Hospital NHS Trust
Chronic Kidney Diseases, Inflammation
Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition
Patients with chronic kidney disease, who have evidence of systemic inflammation with increased cardiovascular risk, will be enrolled into this trial.
- Trial name
- RESCUE (NCT03926117)
- Testing
- Ziltivekimab
- Where
- 49 sites in United States
- Volunteers
- 264 people
- Sponsor
- Novo Nordisk A/S
End Stage Renal Disease
BicMag Study - Improving Mineral Buffering Capacity in Dialysis Patients
The BicMag study is a prospective, randomized, controlled cross-over study that aims to examine the potential additive effect of a dialysate enriched with both bicarbonate and magnesium on mineral buffering capacity in the blood…
- Trial name
- NCT07663279
- Testing
- D-Standard, D-Bic, D-Mag
- Volunteers
- 91 people
- Sponsor
- Elisabethinen Hospital
End-Stage Renal Disease
Cook Enforcer Post-Market Study
The purpose of this study is to evaluate the performance of the Cook Advance® Enforcer™ 35 Focal-Force PTA Balloon Catheter (or Enforcer balloon) in treating narrowed blood vessels compared to treatment with a conventional…
- Trial name
- NCT03552289
- Testing
- Cook Advance® Enforcer 35 Focal-Force Percutaneous Transluminal Angioplasty (PTA) Balloon Catheter, Conventional angioplasty balloon catheters
- Where
- 5 sites in United States
- Volunteers
- 211 people
- Sponsor
- Cook Research Incorporated
Chronic Renal Failure, Humoral Immune Alterations
Improvement of Humoral Immune Response With Hemodialysis on BK-F Membrane: Correlation to Soluble CD40 Clearing
The aim of this study is to improve the humoral immune response efficiency of hemodialyzed patient by the use of PMMA membrane (BK-F) able to clear the soluble form of CD40 in a model of anti-HBV vaccination
- Trial name
- HEPADIAL (NCT01066559)
- Testing
- High flux polymethylmetacrylate membrane, Polysulfone membrane, Hepatitis B serological control
- Where
- 6 sites in France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Bordeaux
End Stage Renal Disease
The Effects of Resistance Exercise and Protein Supplementation in Hemodialysis Patients
The objective of this study is to determine how protein supplementation, with or without exercise, affects functional capacity, strength, body composition, and physical activity in hemodialysis patients.
- Trial name
- NCT00179218
- Testing
- nutritional supplementation, exercise
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Vanderbilt University
End-stage Renal Disease, Malnutrition; Protein
Impact of IDPN on Nutrition Markers in Patients Receiving ICHD
Evaluate the impact of intradialytic parenteral nutrition (IDPN) compounded with Clinisol, Prosol, and/or Clinolipid on albumin levels and weight in patients with end-stage renal disease (ESRD) undergoing in-center hemodialysis.
- Trial name
- NCT05439174
- Testing
- Intradialytic Parenteral Nutrition
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Patient Care America
Renal Osteodystrophy, End Stage Renal Disease
Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance Dialysis
OBJECTIVES: I. Evaluate the separate and combined skeletal effects of recombinant human growth hormone (GH) and calcitriol in patients with adynamic renal osteodystrophy. II.
- Trial name
- NCT00004340
- Testing
- calcitriol, growth hormone
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- National Center for Research Resources (NCRR)
Peritoneal Dialysis-associated Peritonitis, End Stage Renal Disease
In Vitro Analysis of Effluent Dialysate Solution From Patients on Peritoneal Dialysis, With the CloudCath Device
A proof-of-concept study of a prototype CloudCath device designed to detect peritonitis using the effluent dialysate from patients undergoing peritoneal dialysis.
- Trial name
- NCT05300191
- Testing
- Effluent dialysate
- Where
- Mexico
- Volunteers
- 500 people
- Sponsor
- CloudCath
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