Clinical trials: End-stage Renal Failure
Chronic Renal Failure
Efficacy of an Intradialysis Combined Training Program on Disability Level and Physical Performance.
The patient subjected to hemodialysis has a low physical capacity due to being advanced in years and the complexity of the process, which is encouraged by family members and caregivers who lead them to a total dependence.
- Trial name
- PTH-CKD0113 (NCT02883309)
- Testing
- intradialytic physical training program
- Sponsor
- Universidad Austral de Chile
Endocrine System Diseases, Thyroid Diseases
Endocrine Changes and Their Correction in Heart and Lung Transplant Recipients and Donors
The aim of this study is to assess the impact of endocrine changes and their correction on survival and organ function in heart and lung transplant recipients.
- Conditions
- Endocrine System Diseases, Thyroid Diseases, Cortisol Deficiency, Diabetes Insipidus
- Trial name
- NCT04351945
- Testing
- Blood test
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Chronic Renal Failure
Safe Use of Heparin Sodium in Patients With Chronic Renal Failure.
The Heparin form a complex with a plasma protein, antithrombin III (ATIII), which is an endogenous anticoagulant. This complex inhibits the formation of thrombin and accelerates its destruction.
- Trial name
- Heparin (NCT01229072)
- Testing
- Heparin sodic, heparin liquemine
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Azidus Brasil
End-stage Renal Disease
The Role of Hepcidin as a Biomarker to Predict Successful Renal Transplantation
High hepcidin concentrations indicate that iron is blocked from secretion from the reservoir. Hepcidin may be useful in prediction functional iron utilization in renal failure patients.
- Trial name
- NCT04575077
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Nutrition Disorders, Dialysis
Estimate for Dietary Intakes and Hemodialysis Patients
The aim of this clinical research is to evaluate the relevance of using the EPA slide to estimate dietary intakes in dialysis patients.
- Conditions
- Nutrition Disorders, Dialysis, Chronic Renal Failure, Dietetician
- Trial name
- EDDEN (NCT03772171)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Anemia, Renal Failure, Chronic Renal Failure
Effects of Early Correction of Anemia in Patients With Chronic Renal Insufficiency
The purpose of the study is to assess the effect of an early and complete correction of anemia after treatment with epoetin alfa on the rate of progression of chronic renal failure (which involves improper functioning of the…
- Trial name
- NCT00312871
- Testing
- Epoetin alfa
- Volunteers
- 217 people
- Sponsor
- Janssen Cilag S.A.S.
Kidney Disease, End-Stage
Electronic Patient-Reported Outcomes in Clinical Kidney Practice (ePRO Kidney)
People living with end-stage kidney disease (ESKD) need dialysis or transplantation in order to stay alive. This illness and treatment significantly impact peoples' health, emotions, work and relationships.
- Trial name
- NCT03149328
- Testing
- Educational Support
- Where
- 2 sites in Canada
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Chronic Renal Failure
Cost Utility Analysis of Erythropoietin for Anemia Treatment in Hemodialysis Patients
To study the cost utility analysis of Erythropoietin (EPO) for maintaining the different hemoglobin (Hb) target levels in anemic hemodialysis patient in routine clinical practice.
- Trial name
- CUAEPO (NCT01049711)
- Testing
- erythropoietin
- Where
- Thailand
- Volunteers
- 152 people
- Sponsor
- Mahidol University
End Stage Renal Disease, Vascular Access Patency
Determine the Safety/Efficacy of Ticagrelor for Maintaining Patency of Arterio-Venous Fistulae Created for Hemodialysis
This study is a randomized, placebo-controlled, single blind clinical trial. Seventy patients with ESRD on chronic HD and a functioning AVF will be recruited.
- Trial name
- NCT02335099
- Testing
- ticagrelor
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Virginia
Renal Insufficiency, Kidney Diseases
A Study to Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
This is a multicenter, open-label, parallel-group study to evaluate INCB054707 in participants with varying levels of renal function or impairment.
- Trial name
- NCT05624710
- Testing
- INCB054707
- Where
- 4 sites in United States, Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Incyte Corporation
Renal Disease, End Stage
β2M Post-HD Rebound Prediction
β2-Microglobulin is small 11.8 kDa protein presents on the surface of all nucleated cell in the human body, it forms part of the non-variable chain of Major Histocompatibility Complex class I.
- Trial name
- NCT07713680
- Testing
- β2-microglobulin blood concentration in mg/L
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- East and North Hertfordshire NHS Trust
Sleep Apnea, End Stage Renal Disease
Impact of Different Dialysis on Sleep Apnea in Patients With Renal Failure
The purpose of this study is to determine whether hemodiafiltration, a new form of hemodialysis can improve sleep apnea in patients with end stage kidney disease.
- Trial name
- NCT00380848
- Testing
- Hemodiafiltration
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
ESRD (End Stage Renal Disease), Dialysis
Laser Acupuncture for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis.
- Conditions
- ESRD (End Stage Renal Disease), Dialysis, Fatigue
- Trial name
- LA-HD-Fatigue (NCT07538310)
- Testing
- Low-Level Laser Acupuncture (LA)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei City Hospital
Chronic Renal Failure
Post-Marketing Surveillance on Long-Term Drug Use of Kiklin (Bixalomer)® Capsules in Patients With Hyperphosphatemia Receiving Peritoneal Dialysis
To evaluate the safety and efficacy of long-term use of Kiklin® Capsules in actual clinical settings.
- Trial name
- NCT01903213
- Testing
- bixalomer
- Where
- 8 sites in Japan
- Volunteers
- 123 people
- Sponsor
- Astellas Pharma Inc
Inflamation, Hemodialysis
Effect of Sertraline on Inflammation in Hemodialysis Patients with Depression: a Randomized Controlled Trial
Depression is a common mental health condition among patients undergoing hemodialysis and is associated with a lower quality of life, poor treatment adherence, and worse overall health outcomes.
- Conditions
- Inflamation, Hemodialysis, End Stage Renal Disease on Hemodialysis (Diagnosis)
- Trial name
- NCT06840379
- Testing
- Sertraline (Oral Antidepressant)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Nishtar Medical University
End Stage Renal Disease
Trial of Adoptive Immunotherapy With TRACT to Prevent Rejection in Living Donor Kidney Transplant Recipients
Regulatory CD4+CD25+ T cells (Treg) derived from the thymus and/or peripheral tissues have been demonstrated to broadly control T cell reactivity (14).
- Trial name
- TRACT (NCT02145325)
- Testing
- Expanded Tregs
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northwestern University
End Stage Kidney Disease, End Stage Renal Disease
Comparative Outcome Measures of Patients Receiving Acute Renal ThErapy Study
Retrospective, multicenter, comparative, post-market study of the Tablo Hemodialysis System in hospitalized participants with End-Stage Renal Disease or Acute Kidney Injury.
- Conditions
- End Stage Kidney Disease, End Stage Renal Disease, Acute Kidney Injury
- Trial name
- COMPARE (NCT04912024)
- Testing
- Intermittent Renal Replacement Therapy using the Tablo Hemodialysis System, Intermittent Renal Replacement Therapy using Conventional Hemodialysis Systems
- Where
- 2 sites in United States
- Volunteers
- 458 people
- Sponsor
- Outset Medical
End Stage Renal Disease, Cardiovascular Disease
Pomegranate and Hemodialysis Pilot Trial
In this study, the investigators will administer pomegranate juice or fruit extract as a targeted antioxidant therapy to hemodialysis patients.
- Conditions
- End Stage Renal Disease, Cardiovascular Disease, Inflammation
- Trial name
- POM Pilot (NCT01562340)
- Testing
- Pomegranate juice, Pomegranate fruit extract
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
End Stage Renal Disease, Hepatitis C
Kidney Transplants in Hepatitis C Negative Recipients With Hepatitis C Viremic Donors
In this study, individuals without hepatitis C infection who are on the kidney transplant waitlist will receive a kidney from a deceased donor with hepatitis C infection and will be treated for hepatitis C at the same time.
- Trial name
- NCT04575896
- Testing
- Glecaprevir/pibrentasvir
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
End Stage Renal Failure on Dialysis
High Pressure Balloon vs Cutting Balloon
Patients suspected of having AV access stenosis will be referred to the Division of Vascular and Endovascular Surgery by the dialysis center.
- Trial name
- NCT03145662
- Testing
- high pressure balloon, cutting balloon
- Where
- United States
- Sponsor
- University of Toledo Health Science Campus