Clinical trials: Endocarditis Infective
Infective Endocarditis
CopenHeart IE - Integrated Rehabilitation of Patients Treated for Infective Endocarditis
The aim of the study is to describe the effect and meaning of an integrated rehabilitation programme, consisting of physical training and psycho-educational care, for patients treated for infective endocarditis.
- Trial name
- NCT01512615
- Testing
- Complex Cardiac rehabilitation, Control group
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sepsis, Infective Endocarditis
Study of Leukocyte Immunophenotype and the Lipid Transport System as Predictive Biomarkers of Severe Bacterial Infections
Current study evaluates the relationship between cell immunity and lipid transport systems in patients with severe bacterial infections (on the model of pneumonia, infective endocarditis, sepsis) in order to develop new methods…
- Conditions
- Sepsis, Infective Endocarditis, Pneumonia, Bacterial
- Trial name
- NCT04178915
- Testing
- Bood leukocyte subsets, The cholesterol content of the cell membrane of T-cells and monocytes
- Where
- Belarus
- Volunteers
- 100 people
- Sponsor
- The Republican Research and Practical Center for Epidemiology and Microbiology
Infective Endocarditis
Evaluation of Systemic Microvascular Endothelial Dysfunction in Patients Presenting With Infective Endocarditis
Infective endocarditis (IE) is a severe clinical condition with a high in-hospital and 5-year mortality. It has a growing incidence, both related to healthcare and possibly to changes in prophylaxis recommendations regarding oral…
- Trial name
- NCT02940340
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Staphylococcus Aureus Bacteremia, Infective Endocarditis
Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia (ET-AUREUS Study).
The goal of this prospective interventionist cohort study is to assess the prevalence of infective endocarditis in patients with Staphylococcus aureus bacteremia at low risk of this complication.
- Trial name
- ET-AUREUS (NCT05862025)
- Testing
- Echocardiography evaluation
- Where
- Spain
- Volunteers
- 470 people
- Sponsor
- Puerta de Hierro University Hospital
Infective Endocarditis, Response, Acute Phase
Personalized Medicine in Patients With Infective Endocarditis
The hypothesis underlying this work is the identification of different sub phenotypes of patients with infective endocarditis through the study of the host's response to infection.
- Conditions
- Infective Endocarditis, Response, Acute Phase, Treatment
- Trial name
- NCT04838938
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Fundación para la Investigación Biosanitaria del Principado de Asturias
Bacteremia
Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing
The major purposes of this prospective, randomized, clinical study are to: 1. Determine and compare the true incidence, nature, magnitude, and duration (INMD) of bacteremia (bacteria found in the bloodstream) resulting from a…
- Trial name
- NCT00454285
- Testing
- Effect of Amoxicillin on bacteremia following a single-tooth extraction
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Infective Endocarditis, Microbiology
Etiologic Diagnosis Algorithm in Infective Endocarditis
The goal of this study is to evaluate the impact of a diagnostic algorithm combining culture-based and molecular methods on the frequency of etiotropic antibiotic therapy prescription within 14 days of diagnosis of infective…
- Trial name
- NCT07682389
- Testing
- Molecular tests (PCR, sequencing), Standard Clinical Practice
- Where
- 3 sites in Russia
- Volunteers
- 128 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Congenital Heart Disease (CHD), Infective Endocarditis (IE)
Electronic Archive of Patients With Congenital Heart Disease and Diagnosis of Infective Endocarditis
The objective of the study is to create an electronic archive in which to census all newly diagnosed or already diagnosed cases of infective endocarditis and congenital heart disease after 01 January 2022 at the IRCCS AOU Bologna…
- Trial name
- IE-CHD (NCT06777615)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Infective Endocarditis
Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study
Introduction. Comprehensive data on infective endocarditis in developing countries are scarce. Objectives: Description of the characteristics (clinical and microbiological) and assessment of the outcomes of infective endocarditis…
- Trial name
- EndoDev (NCT02128139)
- Where
- 6 sites in Fiji, Laos and 3 more
- Volunteers
- 300 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Infective Endocarditis
Predisposition to Infectious Endocarditis
To evaluate the gender-related elements, a first step will be to analyze the impact of sex ratio on different parameters such as age in endocarditis and the type of underlying valvulopathy and other associated comorbidities.
- Trial name
- NCT03979261
- Testing
- evolution of sex ratio according to age
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Staphylococcus Aureus, Bacteremia
Echocardiography Versus no Echocardiography in S. Aureus Bacteraemia and VIRSTA Score < 3
Staphylococcus aureus is the most frequent cause of both healthcare-associated and community-acquired bloodstream infections worldwide.
- Conditions
- Staphylococcus Aureus, Bacteremia, Infective Endocarditis
- Trial name
- VIRSTA-VAL (NCT06457386)
- Testing
- systematic echocardiography, no echocardiography arm
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endocarditis, Heart Valve Diseases
Early Exercise Training in Patients Following Heart Valve Surgery for Infective Endocarditis.
A prospective, interventional, single-group, single centre study to evaluate the feasibility of early aerobic exercise training in patients following heart valve surgery for infective endocarditis.
- Trial name
- NCT05703022
- Testing
- Aerobic interval training
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- University Hospital of North Norway