Clinical trials: Endocrine Disorder
Low-GI Dietary Education, ADA Dietary Education
Diabetic Educational Eating Plan
By improving glycemic control, many of the devastating complications of diabetes are to a large extent preventable. The use of a low GI (glycemic index) diet to improve glycemic control is relatively new and untested.
- Trial name
- DEEP (NCT00473811)
- Testing
- Low GI, ADA diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Massachusetts, Worcester
Type 2 Diabetes Mellitus
To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase III Study to Evaluate the Efficacy and Safety of JT-003 Add-on in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Metformin and Dapagliflozin
- Trial name
- NCT05296044
- Testing
- JT-003
- Where
- South Korea
- Volunteers
- 245 people
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Diabetes
The Glycaemic Response of Local Foods Using the Continuous Glucose Monitoring System
This study is carried out to determine the effect of high and low GI of local foods using Continuous Glucose Monitoring System (CGMS™) on 24 hour blood glucose profiles.
- Trial name
- NCT03703544
- Testing
- High glycemic index, Low glycemic index
- Where
- Singapore
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Diabetes, Erectile Dysfunction
The Prevalence of Erectile Dysfunction (ED) and ED Related Quality of Life of Diabetic Men
Adult diabetic patients aged above 20 attending the diabetic clinic of National Taiwan University Hospital are invited to attend a face to face screening and interview.
- Trial name
- NCT00173134
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Complex Diabetic Foot Wounds
GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds
A multicenter, open-label, single-arm study to evaluate the safety and efficacy of GrafixCORE® for the treatment of complex diabetic foot wounds with exposed tendon and/or bone.
- Trial name
- NCT02260609
- Testing
- Grafix®
- Where
- 4 sites in United States
- Volunteers
- 31 people
- Sponsor
- Osiris Therapeutics
Diabetic Foot Ulcer
Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)
This is a Phase 2a Multi-Center, Prospective, Randomized, Controlled Study aimed to evaluate the Safety and Efficacy of Topically Applied PEP-TISSEEL in Subjects with Diabetic Foot Ulcers (DFU)
- Trial name
- NCT06319287
- Testing
- PEP (Purified Exosome Product) / TISSEEL
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Rion Inc.
Thyroid Abnormalities
Thyroid Abnormalities Associated With Exposure to Atmospheric Emissions of Radioactive Iodine
Background: An inadequate filtering system at the Mayak nuclear weapons production facility in Ozyorsk, Russia, allowed the release of various radioactive materials, particularly I-131 (radioactive iodine) into the city's…
- Trial name
- NCT00342693
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- National Cancer Institute (NCI)
Type 1 Diabetes
Bromocriptine Quick Release (BCQR) as Adjunct Therapy in Type 1 Diabetes
Type 1 diabetes (T1D) continues to be a disease plagued by hyperglycemia, insulin resistance (IR), and increased cardiovascular disease (CVD) despite advances in insulin delivery and glucose monitoring.
- Trial name
- NCT02544321
- Testing
- Bromocriptine
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes
The Evaluation of Laser Lancing Devices in Adult Type 2 Diabetes Patients
Self monitoring of blood glucose level is crucial in diabetes management, but currently available methods, lancet, have shown low compliance of self monitoring of blood glucose because of pain, keratinization of finger tip…
- Trial name
- NCT05251506
- Testing
- laser lancing device or lancet for blood glucose level measurement
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Korea University Guro Hospital
Type 2 Diabetes, Patient Engagement
The Effect of The Personalized Patient Engagement Plan on Diabetes Management
This study evaluates the effect of Personalized Patient Engagement Plan on diabetes management in patients with at least six months of Type-2 Diabetes.
- Conditions
- Type 2 Diabetes, Patient Engagement, Self Efficacy, Adherence, Patient
- Trial name
- NCT04256304
- Testing
- PHEinAction-Personalized Patient Engagement Plan
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Hacettepe University
Type 2 Diabetes Mellitus
Study on Liver Fat Content and Visceral Fat Mass in Overweight and Obese Type 2 Diabetes Patients After Treatment With Basal Insulin
Primary objective: To compare the change in liver fat content and visceral fat mass (cm2) assessed by MRS (Magnetic Resonance Spectroscopy) and MRI (Magnetic Resonance Image), after 26 weeks of treatment with insulin detemir once…
- Trial name
- NCT01310452
- Testing
- insulin detemir, neutral protamine insulin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fudan University
Pancreatic Cancer Resectable
Early Diagnosis of Pancreatic Cancer Via Deciphering Multi-modal Immunological Signatures
Prospective inclusion of 1000 patients with pancreatic cancer (early-stage pancreatic cancer accounts for approximately 75% of cases), 1000 patients with benign pancreatic diseases, and 1000 healthy individuals as controls.
- Trial name
- NCT06495749
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Diabetes Mellitus Type 2
A Study in Type 2 Diabetes Patients Who Are Taking Moderate Dose Insulin, Looking at the Effects of the Medication Luseogliflozin on Risk of Ketoacidosis and Insulin Resistance.
The goal of this clinical trial is to learn if the drug Luseogliflozin works to treat people with diabetes who are taking moderate dose insulin treatment. It will also learn about the safety of the drug Luseogliflozin.
- Trial name
- LUSIRES (NCT07876258)
- Testing
- Luseogliflozin
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- Aimi Fadilah Mohamad
Health Behavior
Effects of Individual, Dyadic, and Collaborative Plans on Physical Activity in Patient-Partner Dyads
THE AIMS: The project aims at investigating of the effects of three types of planning (individual planning, collaborative planning, and dyadic planning) on physical activity.The influence of three planning interventions are…
- Trial name
- NCT02712255
- Testing
- Individual Planning, Dyadic Planning, Collaborative Planning
- Where
- Poland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Diabetes Mellitus, Type 1, Child
The Effect of Mobile Application on the Pediatric Diabetes Management
Type 1 DM; It is a chronic metabolic disease that develops as a result of the destruction of pancreatic ß cells, which are responsible for insulin production.
- Conditions
- Diabetes Mellitus, Type 1, Child, Adolescent
- Trial name
- DM (NCT05333185)
- Testing
- DİABOT (mobile application robot )
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Dokuz Eylul University
Diabetic Polyneuropathy, Sleep Hygiene
The Effect of Sleep Hygiene Education on Sleep Quality and Quality of Life in Patients With Painful Diabetic Polyneuropathy
This randomized controlled study was designed to the effect of sleep hygiene education on sleep quality and quality of life in patients with painful diabetic polyneuropathy The study was conducted between January 2025 and January…
- Conditions
- Diabetic Polyneuropathy, Sleep Hygiene, Pain
- Trial name
- NCT07646743
- Testing
- sleep hygiene education, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Trakya University
Prostatic Cancer
Metabolic Changes in Prostate Cancer Patients With Androgen-ablation Therapy (AAT)
This is an observational, prospective, non-interventional and multi-centre study, to assess the impact of androgen ablation therapy in blood triglycerides, cholesterol and glucose, body fat distribution and fracture risk to ten…
- Trial name
- UROCOR (NCT01284608)
- Where
- 33 sites in Spain
- Volunteers
- 197 people
- Sponsor
- AstraZeneca
Type 1 Diabetes
Pancreatic Islet Transplantation Into the Gastric Submucosa
The overall objective of this pilot project is to evaluate the safety and efficacy of the gastric submucosal space as a novel site for clinical islet transplantation.
- Trial name
- NCT01571817
- Testing
- Isolated Human Pancreatic Islets
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Andrew Posselt
Diabetes Mellitus
Glucose Clamp Study to Prove Hypo- and Hyperglycemic Episodes Using a Non-invasive Glucose Monitoring Device
Continuous monitoring of the skin tissue glucose concentration on two different study days using glucose sensors that work on the principle of impedance spectroscopy, with systematic alteration of the blood glucose concentration…
- Trial name
- NCT01060917
- Testing
- Non-invasive CGMS (continuous glucose monitoring system), Hyperglycemic and hypoglycemic glucose clamp, Non-invasive CGMS (GlucoDay)
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Profil Institut für Stoffwechselforschung GmbH
Diabetic Wounds, Venous Stasis Wounds
The Role of Lipoaspirate Injection in the Treatment of Diabetic Lower Extremity Wounds and Venous Stasis Ulcers
A prospective, single blinded randomized clinical study will be performed to determine if the injection of lipoaspirate into diabetic or venous stasis wounds promotes wound healing or wound closure at a faster rate than…
- Trial name
- NCT00815217
- Testing
- injection of lipoaspirate, control
- Where
- United States
- Sponsor
- Washington D.C. Veterans Affairs Medical Center
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