Clinical trials: Endocrine Disorder
Diabetes Mellitus, Type 2
A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause
The purpose of the study is to investigate if NNC0519-0130 affects the blood levels of a birth control pill that contains the two hormones ethinylestradiol and levonorgestrel.
- Trial name
- NCT06513104
- Testing
- NNC0519-0130, Levonorgestrel + Ethinylestradiol, Paracetamol
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes (T1D), Sleep Health
Type 1 Diabetes REst for Metabolic Health
Research has shown a link between poor sleep health and late circadian timing with cardiometabolic health in adolescents with type 1 diabetes (T1D).
- Trial name
- T1DREaM (NCT06627504)
- Testing
- Sleep Health and Circadian Timing Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes
Continuous Glucose Monitoring in Youth With Type 2 Diabetes
The purpose of this study is to use a continuous glucose monitor (CGM) to describe the day to day blood glucose variability in youth with type 2 diabetes.
- Trial name
- NCT02293577
- Testing
- continuous glucose monitor
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Epithelial Ovarian Cancer, Ovarian Cancer
89Zr-DFO-Mirvetuximab PET/CT Imaging for Companion Diagnosis and Response Evaluation in Ovarian Cancer
Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer-related death in women, with approximately 320,000 new cases and 200,000 deaths annually worldwide, and its incidence is rising.
- Trial name
- NCT07790939
- Testing
- 89Zr-DFO-Mirvetuximab PET/CT
- Volunteers
- 20 people
- Sponsor
- Peking University Cancer Hospital & Institute
Diabetes Mellitus
Telephone Use for Care of Persons With Diabetes Mellitus.
The purpose of this study is to determine whether phone use contributes to diabetes control.
- Trial name
- TCDM (NCT01972412)
- Testing
- telephone support
- Where
- 2 sites in Brazil
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Type 1 Diabetes
Impact of Eccentric Training in Hypoxia With Creatine on Metabolic Control and VO2max in Patients With Type 1 Diabetes
Exercise plays an important role in treatment of diabetes. In recent years exercise training in normobaric hypoxia is used in training programs for athletes and in rehabilitation and also commercially.
- Trial name
- NCT06345612
- Testing
- hypoxia, normoxia, creatine supplementation
- Where
- Poland
- Volunteers
- 28 people
- Sponsor
- Silesian Centre for Heart Diseases
Type 2 Diabetes Mellitus (T2DM)
Comparative Cardiovascular Effectiveness of GLP-1 RAs vs. Insulin in Early-Onset Type 2 Diabetes
The incidence of early-onset type 2 diabetes (T2D) is increasing globally. People with early-onset T2D have faster beta-cell deterioration and more aggressive diabetes progression than their late-onset counterparts.
- Trial name
- NCT06913881
- Testing
- GLP-1
- Where
- Sweden
- Volunteers
- 92,100 people
- Sponsor
- Karolinska Institutet
Cardiovascular Disease, Diabetes
Care China-Diabetes
This multicenter, prospective, observational registry will assess efficacy and safety outcomes associated with percutaneous coronary intervention (PCI) with implantation of the CYPHER Select™+ Sirolimus-eluting Coronary Stents in…
- Trial name
- NCT00938119
- Where
- 46 sites in China
- Volunteers
- 1,603 people
- Sponsor
- Johnson & Johnson Medical, China
Type 1 Diabetes Mellitus, Adolescent Behavior
Using an mHealth App to Transition Care of Type-1 Diabetes From Parents to Teens
Type 1 diabetes (T1D) afflicts approximately 154,000 people under the age of 20. Most people with T1D are diagnosed at a young age; their parents have to manage their child's condition.
- Conditions
- Type 1 Diabetes Mellitus, Adolescent Behavior, Parent-Child Relations, Communication
- Trial name
- NCT03436628
- Testing
- MyT1DHero
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Diabetes Mellitus, Type 2, Hypertension
Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)
MK-8835-042 (B1521004) is designed to assess the safety and efficacy of an investigational drug, ertugliflozin (MK-8835, PF-04971729), in participants with type 2 diabetes and hypertension.
- Trial name
- NCT01096667
- Testing
- Ertugliflozin 1 mg, Ertugliflozin 5 mg, Ertugliflozin 25 mg
- Volunteers
- 194 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus
Evaluating the Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects
This study's primary objective is to determine the ability of Kombucha to impact blood sugar levels in patients with diabetes mellitus type II.
- Trial name
- NCT04107207
- Testing
- Ginger Kombucha, Ginger Water
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Diabetes Mellitus, Type 2
Lifestyle Intervention for Adults With Diabetes
Physical activity is the cornerstone of good diabetes management, and yet effective physical activity intervention is not available.
- Trial name
- NCT02699307
- Testing
- Counseling
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan
Neoplasms, Solid Tumors
An Exploratory Study of Zanidatamab in HER2-positive Advanced Tumor After at Least One Line of Standard Therapy
The goal of this clinical trial is to learn if Zanidatamab can treat HER2-positive advanced tumors in adults. The main question it aims to answer is: What is the objective response rate of Zanidatamab in adult patients with HER-2…
- Conditions
- Neoplasms, Solid Tumors, HER2 Positive Solid Tumor, Endometrial Neoplasm
- Trial name
- NCT07631871
- Testing
- Zanidatamab
- Volunteers
- 10 people
- Sponsor
- Haihua Yuan
Advanced Cancer, Advanced Malignancies
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
The primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.
- Conditions
- Advanced Cancer, Advanced Malignancies, Bladder Cancer, Cervical Cancer
- Trial name
- ARC-25 (NCT05891171)
- Testing
- AB598, Zimberelimab, Fluorouracil
- Where
- 19 sites in United States, Australia and 1 more
- Volunteers
- 40 people
- Sponsor
- Arcus Biosciences, Inc.
Diabetes Mellitus, Type 2
Effects of a Small Protein and Lipid Preload on Glucose Tolerance in Subjects With Impaired Glucose Homeostasis
The purpose of this study is: to measure the size of the effect on glucose tolerance of a small mixed protein and lipid meal given as a pre-load in individuals with different glucose tolerance status to investigate the underlying…
- Trial name
- NCT02342834
- Testing
- Small mixed protein and lipid meal
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Diabetes Mellitus, Type 1
Islet Cell Transplants for Diabetes
The purpose of this study is to test the safety and efficacy of islet cell transplants for the treatment of type 1 diabetes mellitus.
- Trial name
- NCT00303134
- Testing
- Islet Cell Transplantation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Weill Medical College of Cornell University
Diabetic Kidney Disease
The Multi-Center Clinical Study of Tang Shen Prescription on Type 2 Diabetic Kidney Disease in Early Stage
This study is a randomized, double-blinded, placebo-controlled clinical trial on type 2 diabetic Kidney Disease in early stage ( microalbuminuria excretion rate = 20-200mg/min) to evaluate the therapeutic effect of tang shen…
- Trial name
- NCT03009864
- Testing
- Tangshen Prescription
- Where
- China
- Volunteers
- 632 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Pancreatic Carcinoma
Concurrent Chemoradiotherapy Combined With Immunotherapy in Patients With Potentially Resectable Pancreatic Cancer
The objective of this study is to evaluate the efficacy and safety of concurrent chemoradiotherapy combined with immunotherapy in patients with potentially resectable pancreatic cancer.
- Trial name
- NCT05634564
- Testing
- Tislelizumab, Gemcitabine, Nab paclitaxel
- Where
- China
- Volunteers
- 62 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Pancreatic Cancer
Protocol for High-Risk Assessment, Screening, and Early Detection of Pancreatic Cancer
The purpose of this study is to find out whether Endoscopic Ultrasound (EUS) can detect early stage pre-cancerous or cancerous changes in the pancreas in patients at high-risk for the development of pancreatic cancer.
- Trial name
- NCT01662609
- Testing
- Endoscopic Ultrasound (EUS)
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma
Guadecitabine and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
The purpose of this study is to look at how patients respond to treatment with guadecitabine and pembrolizumab. The researchers will also be looking at the amount of time it takes for cancer to get worse when participants take…
- Conditions
- Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma
- Trial name
- NCT02901899
- Testing
- Guadecitabine, Laboratory Biomarker Analysis, Pembrolizumab
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Northwestern University
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