Clinical trials: Endocrine Disorder
Diabetes Mellitus, Type 2
The Effect of Reiki in Patients With Type-II Diabetes
Aim: To evaluate the effects of Reiki on subjective well-being, happiness, and some metabolic variables in patients with Type-II diabetes.
- Trial name
- NCT06617767
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Osmaniye Korkut Ata University
Ovarian Sex Cord Stromal Tumor, Ovarian Neoplasms
TC or BEP in Treating Patients With Ovarian Malignant Sex Cord-Stromal Tumors
Investigators will conduct the trial to determine whether paclitaxel and cisplatin (PT) has the same curative effects and less adverse effects than bleomycin, etoposide and cisplatin(BEP) among newly diagnosed ovarian malignant…
- Conditions
- Ovarian Sex Cord Stromal Tumor, Ovarian Neoplasms, Ovarian Cancer
- Trial name
- SCST-01 (NCT02429700)
- Testing
- Paclitaxel, Carboplatin, Bleomycin
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Beihua Kong
Achondroplasia, Small for Gestational Age
Adaption and Testing of the Quality of Life in Short Stature Youth (QoLISSY) Questionnaire for Parents With Children From 0-4
The aim of the study is the adaption, implementation and validation of the instrument for the investigation of the short stature specific quality of life (QoLISSY) for children (age 0-4 years) with achondroplasia (ACH), Small for…
- Conditions
- Achondroplasia, Small for Gestational Age, Growth Hormone Deficiency
- Trial name
- NCT05603936
- Testing
- Questionnaire
- Where
- Germany
- Volunteers
- 168 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Type 1 Diabetes Mellitus
Mindfulness for Adolescents With Type 1 Diabetes
Adolescents with Type 1 Diabetes will be invited to the Mindfulness study. They will be randomly assigned to a Control or Active Group.
- Trial name
- NCT03942471
- Testing
- Mindfulness Based Stress Reduction
- Volunteers
- 65 people
- Sponsor
- Duquesne University
Primary Hyperparathyroidism
Primary Hyperparathyroidism: Short-term Calcimimetics Treatment - Relevance for Parathyroid Surgery Decisions?
Patients with primary hyperparathyroidism (pHPT) often present with fatigue, psychological and cognitive symptoms. Improvement in these symptoms after parathyroid adenomectomy (PTX) has been reported.
- Trial name
- NCT02227264
- Testing
- Cinacalcet, parathyroid adenomectomy
- Where
- Sweden
- Volunteers
- 110 people
- Sponsor
- Karolinska University Hospital
Ovarian Cancer
Screening and Identification of Ovarian Cancers
Ovarian cancer is the first mortality rate of gynecologic malignancies. The incidence of ovarian cancer increased in recent 10 years and it has become the ninth cause of malignancies in the women in Taiwan.
- Trial name
- NCT00854399
- Testing
- Staging surgery or debulking surgery
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital
Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it is safe for people who have solid tumors.
- Conditions
- Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck, HER2 Negative Breast Neoplasms, Esophageal Squamous Cell Carcinoma
- Trial name
- NCT04389632
- Testing
- sigvotatug vedotin, pembrolizumab, cisplatin
- Where
- 158 sites in United States, France and 5 more
- Volunteers
- 1,006 people
- Sponsor
- Seagen, a wholly owned subsidiary of Pfizer
Type 1 Diabetes Mellitus
Teleconsultation in Type 1 Diabetes Mellitus
The purpose of this study is to compare the effects on glycemic control of Teleconsultation versus standard visit in outpatient clinic for patients affected by type 1 diabetes mellitus.
- Trial name
- TELEDIAB (NCT02812498)
- Testing
- Teleconsultation, Standard
- Where
- 2 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Niguarda Hospital
Type 1 Diabetes
The Effects of Different Exercise Modalities in Adolescents With Type 1 Diabetes Using AID Systems
Objective: The overall objective of this study is to assess the efficacy of the current recommended guidelines for physical activity (PA) in response to acute moderate intensity continous exercise (MICE) and high intensity…
- Trial name
- MODE2022 (NCT05619198)
- Testing
- High Intensity Interval Exercise, Moderate Intensity Continous Exercise
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Steno Diabetes Center Copenhagen
Polycystic Ovary Syndrome, Overweight
Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)
The purpose of this study is to determine the effects of stress reduction on glucose, blood pressure, quality of life and overall health and well-being in overweight or obese women, either with Polycystic Ovary Syndrome (PCOS) or…
- Conditions
- Polycystic Ovary Syndrome, Overweight, Obesity, Stress, Physiological
- Trial name
- NCT01464398
- Testing
- Stress reduction, Stress reduction with Health education
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Milton S. Hershey Medical Center
AVP Deficiency, Diabetes Insipidus
Plasma Oxytocin Response to Oral Estrogens in Healthy Controls and AVP-Deficiency
The PHOENIX study aims to investigate whether oral estradiol valerate (EV) and ethinylestradiol (EE) can stimulate oxytocin (OXT) and neurophysin-1 (NP-1) release in humans.
- Trial name
- PHOENIX (NCT07361263)
- Testing
- estradiol valerate, esthinylestradiol
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Pancreatic Cancer
S-1 and and Gemcitabine vs Gemcitabine Alone as Adjuvant Chemotherapy for Patients With Resected Pancreatic Cancer
This study is a randomized, open-label, controlled study that will compare the efficacy of S-1 in combination with gemcitabine to gemcitabine alone as adjuvant treatment for patients with surgically resected pancreatic…
- Trial name
- NCT02131493
- Testing
- S-1, Gemcitabine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhejiang University
Diabetes Mellitus Type 2
Effect of Acute Protein Supplementation in Diabetic Patients
The goal of this trial is to test the effect of house cricket (Acheta domesticus) preload on glycemic response in diabetic patients.
- Trial name
- NCT06880614
- Testing
- Oral Glucose Tolerance test (75g 2-hour), Whey, House cricket
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
Diabetes Type 2, Malnutrition
Evaluation of Glycemic Control by Flash Monitoring of Glucose (MFG) in Malnourished Patients With Type 2 Diabetes
Evaluation of Glycemic Control by Flash Monitoring of Glucose (MFG) in Malnourished Patients With Type 2 Diabetes (MFG SNO)
- Trial name
- MFG-SNO (NCT05443204)
- Testing
- Fortimel energy, Nutrision Advanced Diason Energy HP
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Diabetes Mellitus, Type 1
Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes
This is a Phase 3 trial of cadisegliatin as adjunctive therapy to insulin in participants with Type 1 Diabetes Mellitus.
- Trial name
- CATT1 (NCT06334133)
- Testing
- Cadisegliatin 800 mg QD, Cadisegliatin 800 mg BID
- Where
- 48 sites in United States, Puerto Rico
- Volunteers
- 150 people
- Sponsor
- vTv Therapeutics
Growth Hormone Deficiency, Idiopathic Short Stature
Genotropin Study Assessing Use of Injection Pen
Assessment of Genotropin patient and caregiver (Dyad) perception of convenience and preference of Genotropin injection pen. Patients already on genotropin will be asked to use a genotropin pen for 2 months.
- Trial name
- NCT00965484
- Testing
- New Genotropin Pen
- Where
- 25 sites in United States
- Volunteers
- 136 people
- Sponsor
- Pfizer
Depression, Diabetes Mellitus Type 2
Pilot Study of a Self-help Intervention for Depression in Patients With a Chronic Disease
A feasibility pilot trial of the self-help, "Cognitive behavioural therapy" based "Living Life to the Full" Materials for use by patients with diabetes type 2 and / or coronary heart disease.
- Conditions
- Depression, Diabetes Mellitus Type 2, Coronary Heart Disease
- Trial name
- NCT00854984
- Testing
- Living Life to the Full
- Where
- 2 sites in United Kingdom
- Volunteers
- 49 people
- Sponsor
- University of Edinburgh
Brain and Central Nervous System Tumors, Childhood Langerhans Cell Histiocytosis
Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Giving radiation therapy in different ways may kill more tumor cells.
- Conditions
- Brain and Central Nervous System Tumors, Childhood Langerhans Cell Histiocytosis, Gastrointestinal Carcinoid Tumor, Head and Neck Cancer
- Trial name
- NCT00002947
- Testing
- indium In 111 pentetreotide
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Yale University
Diabetic Patients, Type II Diabetes Mellitus
Oleanolic Acid as Therapeutic Adjuvant for Type 2 Diabetes Mellitus (OLTRAD STUDY)
Oleanolic acid (OA), is a natural component of many plant food and medicinal herbs, which has shown to exert in experimental models hypoglycemic and hypolipidemic effects, and also a cytoprotective action against oxidative and…
- Trial name
- OLTRAD (NCT06030544)
- Testing
- OA-enriched functional olive oil, commercial olive oil
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Spanish National Research Council
Metabolic Disease, Insulin Sensitivity
Metabolic Effects of Melatonin Treatment
Modern living is associated with an epidemic of type 2 diabetes mellitus (T2DM). Sleep disturbances such as insomnia or frequent awakenings are strong risk factors for T2DM with several studies indicating a central role of…
- Conditions
- Metabolic Disease, Insulin Sensitivity, Glucose Metabolism Disorders (Including Diabetes Mellitus), Type 2 Diabetes Mellitus
- Trial name
- NCT03859934
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- University of Aarhus
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