Clinical trials: Endocrine System Diseases
Dyslipidemia Associated With Type II Diabetes Mellitus
Paraclinical Cardiometabolic Risk Assessment in Type 2 Diabetes
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by impaired insulin action and increased cardiometabolic risk.
- Trial name
- NCT07362953
- Where
- Turkey (Türkiye)
- Volunteers
- 2,188 people
- Sponsor
- Tokat Gaziosmanpasa University
Neuropathic Pain, Diabetes Mellitus, Type 2
A Randomized, Active-controlled, Parallel, Open-label, Multicenter, Phase 4 Study to Compare the Efficacy and Safety of Pregabalin Sustained Release Tablet and Pregabalin Immediate Release Capsule in Type II Diabetic Patients With Peripheral Neuropathic Pain
This study is to compare the efficacy and safety of pregabalin sustained release tablet and pregabalin immediate release capsule in type II diabetic patients with peripheral neuropathic pain.
- Trial name
- NCT05624853
- Testing
- pregabalin sustained release tablet, pregabalin immediate release capsule
- Where
- 8 sites in South Korea
- Volunteers
- 130 people
- Sponsor
- Yuhan Corporation
Pre Diabetic, Obesity & Overweight
PREdiabetes GLycemic Impact and Data Evaluation
This prospective, randomized controlled trial evaluates whether real-time continuous glucose monitoring (CGM) improves glycemic control and lifestyle adherence in adults with prediabetes compared to conventional self-monitoring…
- Conditions
- Pre Diabetic, Obesity & Overweight, Insulin Resistance
- Trial name
- PRE-GLIDE (NCT07599072)
- Testing
- CGM Sibionics, On-Call Extra Glucometer
- Where
- 3 sites in Ukraine
- Volunteers
- 80 people
- Sponsor
- Nazarii Kobyliak
Premature Ovarian Insufficiency
Phase 1 Clinical Trial of CordSTEM-ST
This clinical study will evaluate the safety and tolerability of CordSTEM-ST after administering a single dose in patients with premature ovarian insufficiency (POI), as well as identify the maximum tolerated dose (MTD) and…
- Trial name
- CBT210-POI_P1 (NCT06578039)
- Testing
- umbilical cord-derived mesenchymal stem cell
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- CHABiotech CO., Ltd
Microsatellite Stable Colorectal Cancer, Pancreatic Cancer
Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer
This research study is studying a combination of drugs with radiation therapy as a possible treatment for Microsatellite Stable Colorectal Cancer, Pancreatic Cancer, or MSI High Colorectal Cancer.
- Conditions
- Microsatellite Stable Colorectal Cancer, Pancreatic Cancer, MSI High Colorectal Cancer
- Trial name
- NCT03104439
- Testing
- Nivolumab, Ipilimumab, Radiation Therapy
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Massachusetts General Hospital
Covid 19
Diagnosis of Endocrine Dysfunctions in Covid-19
As observed with SARS-CoV responsible for SARS 2003, the new coronarovirus SARS-CoV-2 uses the angiotensin converting enzyme type 2 (ACE2) as cellular receptor to infect cells.
- Trial name
- Dyhor-19 (NCT04587375)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Diabetes
Data Therapy Collection to Evaluate Performances of an Automated Insulin Titration Algorithm Compared to Standard Method of Titration
A data collection of blood glucose values, insulin, meal composition will be performed for a period of two months, to evaluate the performances of an automated insulin titration algorithm
- Trial name
- GLUCAL3 (NCT05098301)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Diabetes Mellitus, Macular Edema
Intravitreal Aflibercept Injection in Vision Impairment Due to DME
To determine the efficacy of intravitreally (IVT) administered VEGF Trap-Eye on the best-corrected visual acuity (BCVA) assessed by the early treatment diabetic retinopathy study (ETDRS) chart in subjects with diabetic macular…
- Trial name
- VIVID-DME (NCT01331681)
- Testing
- VEGF Trap-Eye (BAY86-5321), Macular Laser Photocoagulation (Control)
- Where
- 73 sites in Australia, Austria and 9 more
- Volunteers
- 406 people
- Sponsor
- Bayer
Diabetic Foot Ulcer, Mesenchymal Stromal Cells
Effect of Mesenchymal Stem Cells on Healing of Foot Ulcers in Diabetes Patients.
The STEMFOOT Pilot Study is a single center randomized open phase I clinical intervention pilot trial with the aim of investigating the treatment effect of an allogenic adipose-derived mesenchymal stromal cell product (C2C_ASC)…
- Trial name
- STEMFOOT (NCT05595681)
- Testing
- Adipose tissue derived mesenchymal stromal/stem cells (Cell2Cure®)
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Cell to Cure ApS
Ovarian Carcinoma
Immunohistochemical Expression of Epithelial Cell Adhesion Molecule (EpCAM) in Epithelial Ovarian Carcinoma
Cancer stem cells (CSCs) can undergo self-renewal and differentiation. EpCAM is a 40-kDa type I transmembrane glycoprotein composed of a large extracellular domain, one transmembrane region, and a small intracellular domain of 26…
- Trial name
- NCT05576519
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Diabetes Mellitus, Diabetes Complications
Prevalence of Inpatient Hyperglycemia: Risks, Complications and Outcomes
This protocol will determine the prevalence of hyperglycemia and diabetes in the elective orthopedic population at the University of Wisconsin. It will also determine if there is a difference in outcomes.
- Trial name
- NCT00585494
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus, Arterial Hypertension
Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy
The aim of this study is to to analyze if it is possible to reach the goals of HbA1c <7.0% and blood pressure <= 130/80 mm Hg in a cohort of patients with type 2 diabetes attending a primary care unit, using ony those resources…
- Trial name
- NCT00935805
- Testing
- Metformin, Glybenclamide, NPH insulin
- Where
- Brazil
- Volunteers
- 124 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Secondary Hypothyroidism
Recovery Rate in Secondary Hypothyroidism
The aim of this project is to assess the rate of recovery of secondary hypothyroidism in patients with pituitary disorders.
- Trial name
- NCT05276856
- Testing
- Levothyroxine
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Nova Scotia Health Authority
Type 1 Diabetes Mellitus
The Influence of Non-Caloric Artificial Sweeteners on Youth With Type 1 Diabetes
The investigators aim to further the understanding of environmental factors that may underlie variations in body composition seen in youth with Type 1 diabetes (T1D).
- Trial name
- NCT03889522
- Testing
- Bioelectrical Impedance Analysis, Total Body Dual-energy X-ray Absorptiometry, Blood draw
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical College of Wisconsin
Pancreatic Cancer, Cancer of Pancreas
Tosedostat With Capecitabine in Patients With Metastatic Pancreatic Adenocarcinoma
There are two parts to this study: the goal of the first part of the study is to find the best dose of tosedostat when given in combination with capecitabine.
- Conditions
- Pancreatic Cancer, Cancer of Pancreas, Cancer of the Pancreas, Pancreas Cancer
- Trial name
- NCT02352831
- Testing
- Tosedostat, Capecitabine, Fresh tissue biopsy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Washington University School of Medicine
Intermittent Fasting, Gestational Diabetes
Intermittent Fasting on the Incidence of Gestational Diabetes Mellitus Obese Pregnant Women in 3rd Trimester
This randomized controlled clinical trial will assess the impact of intermittent fasting on the incidence of gestational DM in obese pregnant women in 3rd trimester and its effect on maternal and neonatal outcomes.
- Conditions
- Intermittent Fasting, Gestational Diabetes, Obesity
- Trial name
- NCT04853537
- Testing
- intermittent fasting diet
- Volunteers
- 252 people
- Sponsor
- Ain Shams University
Diabetes Mellitus Type 2
Insulin Analogue With Continuous Glucose Monitoring System (CGMS) Measurement
Primary objective: Difference in frequency of subjects with conventionally detected hypoglycemia by the subject [at least one measurement smaller/equal 60mg/dl documented in the 8-point profile in the case record form (CRF) or…
- Trial name
- SAFIR (NCT00354939)
- Testing
- Insulin glargine
- Volunteers
- 480 people
- Sponsor
- Sanofi
Type 2 Diabetes
Evaluation of White Sweet Potato Tube Feeding Formula on Type 2 Diabetic Residents in Long-term Care Institutions
In order to response the increasing of aging population cause losing ability that need long-care needs, the project entitled "10-year long-term care program" from Executive Yuan in 2007 is carried out to assist economically…
- Trial name
- NCT02711839
- Testing
- Commercial diabetic formula, White sweet potato formula
- Volunteers
- 54 people
- Sponsor
- Taipei Medical University
Type 2 Diabetes
Multiple Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes
BMS-820132 is an investigational new drug being developed by BMS for treating Type 2 diabetes. The purpose of this study is to test the safety/tolerability (potential side effects) of multiple doses of the investigational new…
- Trial name
- NCT01290575
- Testing
- BMS-820132
- Where
- 5 sites in United States
- Volunteers
- 67 people
- Sponsor
- Bristol-Myers Squibb
Type 2 Diabetes, Diabetes
Improving Self Management Skills of Older Adults With Diabetes
The study will help determine if the Better Choices Better Health Diabetes program (community-based or online, also known as the Diabetes Self-Management Program) improves the hbA1C of people with Type-II diabetes.
- Trial name
- NCT01943357
- Testing
- Diabetes Self Management Program
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Stanford University