Clinical trials: Endocrine System Disorder
Type 2 Diabetes Mellitus
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the efficacy of the study drug tirzepatide in participants with type 2 diabetes mellitus.
- Trial name
- NCT03131687
- Testing
- tirzepatide, Dulaglutide
- Where
- 49 sites in United States, Poland and 2 more
- Volunteers
- 318 people
- Sponsor
- Eli Lilly and Company
Fallopian Tube Adenocarcinoma, Fallopian Tube Clear Cell Adenocarcinoma
YKL-40 in Serum Samples From Patients With Newly Diagnosed Stage III-IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer Receiving Chemotherapy
This research trial studies chitinase 3-like 1 (cartilage glycoprotein-39) (YKL-40) in serum samples from patients with newly diagnosed stage III-IV ovarian epithelial, primary peritoneal cavity, or fallopian tube cancer…
- Conditions
- Fallopian Tube Adenocarcinoma, Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma
- Trial name
- NCT00899093
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
- Where
- 131 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Gynecologic Oncology Group
Diabetes Mellitus, Diabetic Nephropathy
Role of Triglyceride-Glucose Index and Inflammatory Biomarkers as Prognostic Tools for Progression of Diabetic Nephropathy
This study aims to evaluate the prognostic value of the Triglyceride-Glucose (TyG) index alongside inflammatory biomarkers in predicting the progression of diabetic nephropathy, exploring their correlation with disease severity…
- Trial name
- NCT07813793
- Volunteers
- 105 people
- Sponsor
- Assiut University
Cholecystitis, Acute, Pancreas Cancer, Duct Cell Adenocarcinoma
Safety and Efficacy of EUS-guided Gallbladder Drainage Under Endoscopist-directed Conscious Sedation
This prospective single-center study was designed by the investigators to evaluate the feasibility, safety, and efficacy of endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) performed under endoscopist-directed…
- Conditions
- Cholecystitis, Acute, Pancreas Cancer, Duct Cell Adenocarcinoma, Cholangiocarcinoma
- Trial name
- NCT07704021
- Testing
- Sedation
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Epithelial Ovarian Cancer, Fallopian Tube Cancer
Total/Subtotal Colectomy in Ovarian Cancer
The purpose of this study is to evaluate the safety and one year disease-free survival of total or subtotal colectomy and proctocolectomy in stage IIIc and stage IV epithelial ovarian, fallopian tube, and primary peritoneal…
- Conditions
- Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma, Secondary Malignant Neoplasm of Large Intestine
- Trial name
- NCT02595021
- Testing
- Total or Subtotal Colectomy, Other Bowel Resection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Gynecologic Oncology Group
Hyponatremia, SIADH
Tolvaptan for Patients With Acute Neurological Injuries
Hyponatremia occurs frequently in patients with acute brain injury in the days to weeks following injury, and may contribute to adverse outcome.
- Trial name
- NCT02545114
- Testing
- Tolvaptan
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Polderman, Kees, H., MD, PhD
Gestational Diabetes Mellitus
Trial of Diet in Gestational Diabetes Mellitus: Metabolic Consequences to Mother and Offspring
The rapidly rising risk of gestational diabetes pregnant women demands that an effective diet strategy be developed due to the high risk of fetal overgrowth, which places the newborn at increased risk for childhood obesity and…
- Trial name
- CHOICE (NCT02244814)
- Testing
- Low Carbohydrate/Conventional, Choosing Healthy Options in Carbohydrate Energy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Colorado, Denver
Graves' Ophthalmopathy
Retinal Oxygen Saturation in Patients With Graves' Ophthalmopathy and in Normal People
Find if the retinal function is affected in both the nonsevere and the severe stage of Graves' ophthalmopathy (GO) by comparing the retinal oxygen saturation of GO patients with that of normal people.
- Trial name
- NCT02290704
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Diabetes Mellitus, Type 2
A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause
The purpose of the study is to investigate if NNC0519-0130 affects the blood levels of a birth control pill that contains the two hormones ethinylestradiol and levonorgestrel.
- Trial name
- NCT06513104
- Testing
- NNC0519-0130, Levonorgestrel + Ethinylestradiol, Paracetamol
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes (T1D), Sleep Health
Type 1 Diabetes REst for Metabolic Health
Research has shown a link between poor sleep health and late circadian timing with cardiometabolic health in adolescents with type 1 diabetes (T1D).
- Trial name
- T1DREaM (NCT06627504)
- Testing
- Sleep Health and Circadian Timing Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes
Continuous Glucose Monitoring in Youth With Type 2 Diabetes
The purpose of this study is to use a continuous glucose monitor (CGM) to describe the day to day blood glucose variability in youth with type 2 diabetes.
- Trial name
- NCT02293577
- Testing
- continuous glucose monitor
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Epithelial Ovarian Cancer, Ovarian Cancer
89Zr-DFO-Mirvetuximab PET/CT Imaging for Companion Diagnosis and Response Evaluation in Ovarian Cancer
Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer-related death in women, with approximately 320,000 new cases and 200,000 deaths annually worldwide, and its incidence is rising.
- Trial name
- NCT07790939
- Testing
- 89Zr-DFO-Mirvetuximab PET/CT
- Volunteers
- 20 people
- Sponsor
- Peking University Cancer Hospital & Institute
Diabetes Mellitus
Telephone Use for Care of Persons With Diabetes Mellitus.
The purpose of this study is to determine whether phone use contributes to diabetes control.
- Trial name
- TCDM (NCT01972412)
- Testing
- telephone support
- Where
- 2 sites in Brazil
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Type 1 Diabetes
Impact of Eccentric Training in Hypoxia With Creatine on Metabolic Control and VO2max in Patients With Type 1 Diabetes
Exercise plays an important role in treatment of diabetes. In recent years exercise training in normobaric hypoxia is used in training programs for athletes and in rehabilitation and also commercially.
- Trial name
- NCT06345612
- Testing
- hypoxia, normoxia, creatine supplementation
- Where
- Poland
- Volunteers
- 28 people
- Sponsor
- Silesian Centre for Heart Diseases
Type 2 Diabetes Mellitus (T2DM)
Comparative Cardiovascular Effectiveness of GLP-1 RAs vs. Insulin in Early-Onset Type 2 Diabetes
The incidence of early-onset type 2 diabetes (T2D) is increasing globally. People with early-onset T2D have faster beta-cell deterioration and more aggressive diabetes progression than their late-onset counterparts.
- Trial name
- NCT06913881
- Testing
- GLP-1
- Where
- Sweden
- Volunteers
- 92,100 people
- Sponsor
- Karolinska Institutet
Cardiovascular Disease, Diabetes
Care China-Diabetes
This multicenter, prospective, observational registry will assess efficacy and safety outcomes associated with percutaneous coronary intervention (PCI) with implantation of the CYPHER Select™+ Sirolimus-eluting Coronary Stents in…
- Trial name
- NCT00938119
- Where
- 46 sites in China
- Volunteers
- 1,603 people
- Sponsor
- Johnson & Johnson Medical, China
Type 1 Diabetes Mellitus, Adolescent Behavior
Using an mHealth App to Transition Care of Type-1 Diabetes From Parents to Teens
Type 1 diabetes (T1D) afflicts approximately 154,000 people under the age of 20. Most people with T1D are diagnosed at a young age; their parents have to manage their child's condition.
- Conditions
- Type 1 Diabetes Mellitus, Adolescent Behavior, Parent-Child Relations, Communication
- Trial name
- NCT03436628
- Testing
- MyT1DHero
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Diabetes Mellitus, Type 2, Hypertension
Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)
MK-8835-042 (B1521004) is designed to assess the safety and efficacy of an investigational drug, ertugliflozin (MK-8835, PF-04971729), in participants with type 2 diabetes and hypertension.
- Trial name
- NCT01096667
- Testing
- Ertugliflozin 1 mg, Ertugliflozin 5 mg, Ertugliflozin 25 mg
- Volunteers
- 194 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus
Evaluating the Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects
This study's primary objective is to determine the ability of Kombucha to impact blood sugar levels in patients with diabetes mellitus type II.
- Trial name
- NCT04107207
- Testing
- Ginger Kombucha, Ginger Water
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Diabetes Mellitus, Type 2
Lifestyle Intervention for Adults With Diabetes
Physical activity is the cornerstone of good diabetes management, and yet effective physical activity intervention is not available.
- Trial name
- NCT02699307
- Testing
- Counseling
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.