Clinical trials: Endometrial Disease
Endometrial Cancer
Ketohexokinase Isoforms in Endometrial Cancer.
Our preliminary analysis with clinical database suggested that, in patients with type I endometrial cancer, high ketohexokinase-expressing group have lower survival probabilities than low ketohexokinase-expressing group.
- Trial name
- NCT03931265
- Testing
- ketohexokinase
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Far Eastern Memorial Hospital
Postmenopausal Women, Intrauterine Diseases
Office Hysteroscopy in Postmenopausal Women: A Randomized Trial of Cervical Preparation Strategies
The goal of this randomized controlled trial is to evaluate the effectiveness of different cervical preparation strategies before office hysteroscopy in postmenopausal women undergoing evaluation for intrauterine pathology.
- Conditions
- Postmenopausal Women, Intrauterine Diseases, Endometrial Pathology, Postmenopausal Bleeding
- Trial name
- NCT07697781
- Testing
- No Cervical Preparation, Misoprostol ( Cytotec) 200 microgram a tablet, Vaginal Estrogen (7-Day Regimen)
- Where
- Tunisia
- Volunteers
- 120 people
- Sponsor
- Faculty of Medicine of Tunis
Infertility
Endometrial Curettage Before Embryo Transfer
Studies have shown that endometrial sampling in the month prior to embryo transfer may increase pregnancy rates. We wish to test this hypothesis by performing a hysteroscopy and curettage in the month proceeding embryo transfer…
- Trial name
- NCT00367367
- Testing
- Hysteroscopy and Curettage
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Head and Neck Cancer, Gynecologic Cancer
Quality of Life Assessment of Radiotherapy in Recurrent Head and Neck Cancer
The purpose of this study is to examine the uses of a mobile health-based assessment and symptom monitoring platform.
- Conditions
- Head and Neck Cancer, Gynecologic Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- NCT05850663
- Testing
- Ecologic Momentary Assessment (EMA)
- Sponsor
- University of Oklahoma
Uterine Bleeding, Treatment Failures
Clinical Predictive Factors of Success of Hysteroscopic Endometrial Ablation/Resection
To determine the predictive factors of endometrial ablation failure in the management of uterine bleeding.
- Conditions
- Uterine Bleeding, Treatment Failures, Prognostic Factors
- Trial name
- NCT05483348
- Testing
- Endometrial Ablation, Repeated gynecological procedure
- Where
- Jordan
- Volunteers
- 95 people
- Sponsor
- Naser Al-Husban
Endometrial Cancer, Postmenopausal Bleeding
Patient's Experience and Choice Between Investigations for Endometrial Cancer in Postmenopausal Bleeding
Endometrial cancer is the most common malignancy of the female genital tract in Hong Kong. The aim in the evaluation of PMB is to exclude underlying malignancy.
- Trial name
- NCT03330015
- Where
- Hong Kong
- Volunteers
- 206 people
- Sponsor
- Chinese University of Hong Kong
Endometrial Hyperplasia
Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Management of Atypical Endometrial Hyperplasia
The purpose of this research study is to compare the uterus tissue of women who receive an intrauterine system to treat their endometrial hyperplasia with the uterine tissue of women who receive megestrol acetate to treat their…
- Trial name
- NCT04897217
- Testing
- Megestrol Acetate, Levonorgestrel Drug Implant
- Sponsor
- Wake Forest University Health Sciences
Endometrial Cancer, Cardiovascular Diseases
Strive Cardio for Endometrial Cancer Survivors
STRIVE Cardio is a 12-week exercise intervention study with the goal to improve functional fitness and cardiovascular health for women who have completed treatment for non-metastatic endometrial cancer within the last five years…
- Trial name
- NCT06534008
- Testing
- 12-week home-based exercise intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Jess S. Gorzelitz
Endometrial Cancer
Zoptarelin Doxorubicin (AEZS 108) as Second Line Therapy for Endometrial Cancer
Open-label, randomized, active-controlled, two-arm Phase III study to compare the efficacy and safety of AEZS-108 and doxorubicin.
- Trial name
- ZoptEC (NCT01767155)
- Testing
- AEZS-108 / zoptarelin doxorubicin, doxorubicin
- Where
- 123 sites in United States, Austria and 20 more
- Volunteers
- 511 people
- Sponsor
- AEterna Zentaris
Endometrial Cancer, Uterine Cancer
Radiomics and Molecular Classification in Endometrial Cancer
Molecular/genomic profiling is the most accurate method to assess the prognosis of endometrial cancer patients. Interestingly, the adoption of radiomics showed important results, across various oncologic specialties.
- Conditions
- Endometrial Cancer, Uterine Cancer, Endometrium Tumor
- Trial name
- ROME (NCT06963385)
- Testing
- Radiomics
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Cervical Cancers, Endometrial Cancer
Emergence of Bacterial Resistance to Antibiotics in the Digestive Microbiota of Patients Treated With Anticancer Drugs
Solid cancers are frequently treated with chemotherapies that target the DNA of cancer cells. It has recently come to light that bacteria are also the target of chemotherapies used in oncology.
- Conditions
- Cervical Cancers, Endometrial Cancer, Gynecological Cancers, Pancreatic Adenocarcinoma
- Trial name
- RAMA (NCT07093593)
- Testing
- Mandatory biological samples (blood and sell)
- Volunteers
- 260 people
- Sponsor
- Centre Georges Francois Leclerc
Intrauterine Adhesions, Exosomes
Clinical Study on the Effect of Umbilical Cord Mesenchymal Stem Cell Exosomes on Endometrial Repair of Intrauterine Adhesions
Intrauterine adhesions (IUA) is a group of diseases caused by endometrial injury leading to occlusion of the uterine cavity and serious abnormality of the uterine cavity morphology, which causes primary or secondary infertility…
- Trial name
- NCT07416578
- Testing
- Exosmoes, HRT
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Endometrial Cancer
3 Year Recurrence Free Survival in Ultra-low-risk Endometrial Cancer
To verify the safety of omission of lymph node dissection in ultra-low-risk endometrial cancer (KGOG criteria), we examine the survival of women with ultra-low-risk endometrial cancer who do not undergo lymph node dissection
- Trial name
- TREE PRO (NCT04227249)
- Testing
- no lymph node dissection
- Volunteers
- 153 people
- Sponsor
- Seoul National University Hospital
Endometrial Cancer
Comparison of Nodal Staging in Endometrial Cancer
This study aims to estimate the recurrence-free survival rates in women with endometrial cancer treated with selective versus sentinel node surgical staging.
- Trial name
- NCT04970368
- Testing
- Sentinel node procedure, Selective staging
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Frederick R. Ueland, M.D.
Cancer
Aminocamptothecin in Treating Patients With Advanced Cancer of the Peritoneal Cavity
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of aminocamptothecin in treating patients with advanced…
- Trial name
- NCT00003548
- Testing
- aminocamptothecin colloidal dispersion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Endometriosis, Adenomyosis of Uterus
Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine
The goal of this observational study is to develop and validate artificial intelligence (AI)-based algorithms that support ultrasound diagnosis of endometriosis, adenomyosis, myometrial masses, uterine malformations, and impaired…
- Conditions
- Endometriosis, Adenomyosis of Uterus, Leiomyoma (Uterine Fibroids), Uterine Neoplasms
- Trial name
- AUDRIE (NCT07810920)
- Where
- Hungary
- Volunteers
- 1,600 people
- Sponsor
- Semmelweis University
Endometrial Cancer
Study of Post Operative Pain in Endometrial Cancer Robotic Versus Laparotomy
This study is being done to evaluate the efficacy of robotic approach for staging of endometrial cancer as compared to an equivalent abdominal approach.
- Trial name
- NCT00909896
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Endometrial Atypical Hyperplasia, Endometrial Adenocarcinoma
Megestrol Acetate Plus Metformin to Megestrol Acetate in Patients With Endometrial Atypical Hyperplasia or Early Stage Endometrial Adenocarcinoma
The purpose of this study is to see if megestrol acetate plus metformin will be more effective in returning the endometrial tissue to a normal state than megestrol acetate alone in patients with endometrial atypical hyperplasia…
- Trial name
- NCT01968317
- Testing
- Megestrol acetate and metformin, Megestrol acetate
- Where
- 5 sites in China
- Volunteers
- 150 people
- Sponsor
- Xiaojun Chen
Cervical Cancer, Endometrial Cancer
A Cohort Study of Uterine Malignancies
The purposes of current study were to explore the relationship between cervical cancer/endometrial cancer and demographic information, behavior and life style, pregnancy-related factors, and disease history, and to study the…
- Trial name
- NCT05635123
- Testing
- No intervention
- Where
- China
- Volunteers
- 6,200 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Myoma, Uterine Bleeding, Dysfunctional
Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy
A prospective observational study on italian women undergoing ulipristal acetate (uPa) therapy for symptomatic myomas and its impact on symptomatology and moreover on myomas architecture.
- Conditions
- Myoma, Uterine Bleeding, Dysfunctional, Uterine Bleeding Heavy, Dysmenorrhea
- Trial name
- NCT03972917
- Testing
- Transvaginal ultrasonographic examination
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- University of Campania Luigi Vanvitelli
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