Clinical trials: Endometrial Hyperplasia
Cardiovascular Diseases, Endometrial Hyperplasia
Soy Estrogen Alternative Study (SEA)
To conduct a three-armed trial assessing the effect of soy phytoestrogens on menopausal complaints, plasma lipids and lipoproteins, vaginal bleeding and endometrial proliferation, and health related quality of life.
- Conditions
- Cardiovascular Diseases, Endometrial Hyperplasia, Heart Diseases, Menopausal Complaints
- Trial name
- NCT00000612
- Testing
- estrogens, conjugated, diet, soy proteins, dietary supplements
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Abnormal Uterine Bleeding
Transvaginal Ultrasound in Women With Abnormal Uterine Bleeding
The objective of this study is to investigate the role of transvaginal ultrasound in detecting endometrial hyperplasia and endometrial cancer in women aged more than 35 presenting with abnormal uterine bleeding.
- Trial name
- NCT01786798
- Testing
- Transvaginal sonography
- Where
- Thailand
- Volunteers
- 560 people
- Sponsor
- Chulalongkorn University
Endometrial Hyperplasia
Comparison of Dilatation & Curettage and Endometrial Aspiration Biopsy Accuracy in Patients Treated With Progestin for Endometrial Hyperplasia: A Korean Gynecologic Oncology Group Study
A prospective multicenter trial has been started in Korea to evaluate the diagnostic accuracy of endometrial aspiration biopsy compared with D\&C in patients treated with progestin for endometrial hyperplasia (EH).
- Trial name
- NCT02412072
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Korean Gynecologic Oncology Group
Endometrial Hyperplasia
Ultrasound and Endometrial Hyperplasia
The investigators hypothesize that endometrial thickness will be a significant predictor of endometrial hyperplasia in a postmenopausal female population with metabolic syndrome: diabetes and/or insulin resistance, hypertension…
- Trial name
- NCT00123188
- Testing
- Ultrasound and Biopsy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Atypical Endometrial Hyperplasia, Endometrial Adenocarcinoma
Megestrol Acetate or Levonorgestrel-Releasing Intrauterine System in Treating Patients With Atypical Endometrial Hyperplasia or Endometrial Cancer
This randomized phase II trial studies how well megestrol acetate or levonorgestrel-releasing intrauterine system works in treating patients with atypical endometrial hyperplasia or endometrial cancer.
- Conditions
- Atypical Endometrial Hyperplasia, Endometrial Adenocarcinoma, Recurrent Endometrial Carcinoma, Stage IA Endometrial Carcinoma
- Trial name
- NCT01943058
- Testing
- megestrol acetate, levonorgestrel-releasing intrauterine system, laboratory biomarker analysis
- Sponsor
- University of Southern California
Endometrial Hyperplasia
Women With Asymptomatic Endometrial Hyperplasia
The purpose of this study is to evaluate the clinical meaning of an endometrial hyperplasia diagnosed using a vaginal ultrasound during routine gynecological examination.
- Trial name
- FAME-ENDO (NCT02100137)
- Testing
- vaginal ultrasound
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Endometrial Hyperplasia, Osteoporosis
Study Evaluating Bazedoxifene/Conjugated Estrogens Combinations In Postmenopausal Women
The purpose of this study is to determine whether bazedoxifene/conjugated estrogens combinations are effective for the prevention of endometrial hyperplasia and for the prevention of osteoporosis in postmenopausal women.
- Trial name
- NCT00242710
- Testing
- Bazedoxifene/Conjugated Estrogen, CE 0.45 mg/MPA 1.5mg
- Where
- 9 sites in United States
- Volunteers
- 1,083 people
- Sponsor
- Pfizer
Endometrial Polyp., Malignant and Pre-malignant Changes in the Polyp
Incidence of Malignant and Premalignant Endometrial Polyp in Asymptomatic and Symptomatic Postmenopausal Women
The prevalence of endometrial polyp is 24% in the general population but is much higher in postmenopausal women. The incidence of malignant or pre-malignant findings in endometrial polyps ranges from 2 to 10% in menopausal women.
- Trial name
- NCT01203176
- Testing
- Hysteroscopic polypectomy
- Where
- Israel
- Volunteers
- 1,400 people
- Sponsor
- Arie Lissak, MD
Endometrial Hyperplasia
Treatment of Endometrial Hyperplasia With an Intrauterine Device (IUD)
The purpose of this research is to determine the effectiveness of the intrauterine device (IUD) called Mirena when compared to the Provera tablets used in treating this condition.
- Trial name
- NCT00123175
- Testing
- Intrauterine Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Endometrial Hyperplasia
Management of Endometrial Hyperplasia With a LNG-IUS: Multicenter Study: KGOG2006
A prospective multicenter trial has been started in Korea to investigate the treatment efficacy of Levonorgestrel-releasing intrauterine system (LNG-IUS) in endometrial hyperplasia (EH) patients.
- Trial name
- KGOG2006 (NCT01234818)
- Testing
- Mirena (LNG-IUS)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Korean Gynecologic Oncology Group
Endometrial Hyperplasia
Efficacy of LNG-IUS for Treatment of Non-atypical Endometrial Hyperplasia in Perimenopausal Women
The purpose of this study is to compare the efficacy of the Levonorgestrel releasing Intrauterine System (Mirena) and Norethisterone Acetate for treatment of non-atypical endometrial hyperplasia in perimenopausal women.
- Trial name
- NCT01499602
- Testing
- LNG-IUS; Mirena; Bayer Schering Pharma Oy, Finland, Norethisterone Acetate tablets
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Atypical Endometrial Polyps, Atypical Endometrial Hyperplasia
Resectoscopic Treatment of Atypical Endometrial Polyps in Fertile Women
The study aims to evaluate the long-term efficacy and prognosis of hysteroscopic resection and coagulation of the base of endometrial polyps with focal atypia in fertile women.
- Trial name
- NCT00490087
- Testing
- Levonorgestrel intrauterine device (IUD)
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- IRCCS Burlo Garofolo
Endometrial Carcinoma
Risk Factors for Concurrent Endometrial Carcinoma in Patients With a Curettage Diagnosis of Endometrial Hyperplasia
Objective: To examine the risk factors for coexisting endometrial carcinoma in patients with endometrial hyperplasia. Method: Seventy-seven patients who received hysterectomy for endometrial hyperplasia were enrolled and divided…
- Trial name
- NCT01273636
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Endometrial Hyperplasia, Endometrial Cancer
Efficacy and Tolerability Study of Progesterone Vaginal Tablets (Endometrin®) in Menopausal Women Treated by Estrogen
The objective of the study is to confirm that the efficacy of vaginal progesterone is at least as good as oral progesterone in order to protect the endometrium of uncontrolled proliferation and prevent endometrial cancer.
- Trial name
- NCT00919919
- Testing
- progesterone, activella
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Endometrial Hyperplasia
Genistein and Endometrial Hyperplasia
The aim of this study is to verify the anti-estrogenic activity of Genistein, on the "non atypical endometrial hyperplasia", in premenopausal women.
- Trial name
- NCT00453960
- Testing
- Genivis, Norethisterone Acetate
- Where
- Italy
- Volunteers
- 59 people
- Sponsor
- University of Messina
Endometrial Hyperplasia, Osteoporosis
Study Evaluating Safety and Efficacy of Bazedoxifene/Conjugated Estrogens Combinations in Postmenopausal Women
The purpose of this study is to determine whether bazedoxifene/conjugated estrogens combinations are effective for the prevention of endometrial hyperplasia and for the prevention of osteoporosis in postmenopausal women.
- Trial name
- NCT00675688
- Testing
- Bazedoxifene/Conjugate Estrogens (CE), Raloxifene
- Volunteers
- 3,544 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer