Clinical trials: Endometrial Receptivity
Endometrial Receptivity, Repeated Implantation Failure
The Clinical Efficiency of Tb-ERA in Chinese RIF Patients
In order to further explore the clinical utility of endometrial receptivity array in patients with repeated implantation failure, the patients divide into the experimental group or the control group.
- Trial name
- NCT04497558
- Testing
- Endometrium biopsy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility
Comparison of Transfers of Fresh and Thawed Embryos in Normal Responder Patients
This study tests the hypothesis that controlled ovarian stimulation impairs endometrial receptivity in normal responders.
- Trial name
- NCT00963625
- Testing
- Embryo cryopreservation, Fresh blastocyst transfer
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Endometrial Receptivity;RNA; Progesterone
Clinical Study on Endometrial Receptivity
to explore the differential expression of miRNA in the implantation window of patients with endometriosis and the time of progesterone and route of administration on planting window
- Trial name
- NCT03687021
- Testing
- Progesterone
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Infertility of Uterine Origin
Development of a Microbiome Non-invasive Diagnosis Tool
Although the endometrium tissue has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- ERA-niMIC (NCT03330444)
- Testing
- Endometrial biopsy and endometrial fluid collection
- Where
- 13 sites in United States, Argentina and 6 more
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Igenomix
Pregnancy Related
Transcriptome Profiling and Endometrial Receptivity
The aim of this study is to correlate and identify the biochemical markers which may reflect WOI. Blood samples will be collected and endometrial biopsy will be performed at particular time points.
- Trial name
- NCT03925311
- Testing
- endometrial biopsy and blood sampling
- Where
- Hong Kong
- Volunteers
- 220 people
- Sponsor
- Chinese University of Hong Kong
Endometriosis, Adenomyosis of Uterus
Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine
The goal of this observational study is to develop and validate artificial intelligence (AI)-based algorithms that support ultrasound diagnosis of endometriosis, adenomyosis, myometrial masses, uterine malformations, and impaired…
- Conditions
- Endometriosis, Adenomyosis of Uterus, Leiomyoma (Uterine Fibroids), Uterine Neoplasms
- Trial name
- AUDRIE (NCT07810920)
- Where
- Hungary
- Volunteers
- 1,600 people
- Sponsor
- Semmelweis University
Chronic Endometritis
Diagnosis of Chronic Endometritis in Endometrial Fluid Using Molecular Techniques to Improve the Outcomes of Assisted Reproductive Treatments
Chronic endometritis (CE) is a persistent inflammation of the endometrial lining caused by the infection of the uterine cavity mainly by bacterial pathogens.
- Trial name
- ChEndometritis (NCT03169621)
- Testing
- Endometrial Biopsy and endometrial fluid collection
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Igenomix
Assess the Efficacy of Differentiated and Undifferentiated Stem Cell Therapy in Improving Endometrial Receptivity.
Role of Stem Cells in Improving Implantation Rates in ICSI Patients
Background: Improving implantation rates in ICSI cycles has been the focus of research in recent decades. Because success rates is not satisfactory enough especially when transferring good embryos to the uterine cavity and…
- Trial name
- NCT01649752
- Testing
- Differentiated stem cells to endometrium is deposited in the uterine cavity through an IUI catheter, Undifferentiated MSC is deposited in the uterine cavity through an IUI catheter.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Infertile
Receptivity Assessment of Homogeneous Endometrium in Late Follicle Phase
Twenty eight infertile women undergoing ultrasonographic endometrial assessment in the late follicle phase, fourteen of them with homogeneous echo endometrium (group 1) and other fourteen with trilaminar endometrium (group 2)…
- Trial name
- NCT01533350
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Shen-Zhen City Maternity and Child Healthcare Hospital
Luteal Phase Defect
Effects of Varied Estrogen Doses on Endometrial Receptivity
This study will help determine the effect of varied estradiol levels on the uterine lining in healthy humans that are not undergoing a stimulated in vitro fertilization (IVF) cycle.
- Trial name
- NCT02458404
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Endometrial Receptivity
Microbiome and Endometrial Receptivity in Obese Infertile Women
The objective of this project is the identification and quantification of the main bacterial communities present in the endometrial microbiota in obese infertile patients, to assess if there is an alteration of their composition…
- Trial name
- NCT03493529
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Endometrial Receptivity
Comparison of Blood Flow in the Arteriae Uterinae in Ovarian Stimulation Cycles
This study will measure the blood flow in the aa. uterinae in women, undergoing firstly ovarian stimulation for In-Vitro Fertilization (IVF) / Intracytoplasmic sperm injection (ICSI), in Hormonal Replacement cycles (HRT) and…
- Trial name
- NCT03887728
- Where
- United Arab Emirates
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Endometrial Receptivity
Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation
Both controlled ovarian stimulation (COS) and frozen embryo transfer has become an integral part of in vitro fertilization (IVF) treatment.
- Trial name
- HormoSenoRec (NCT06280560)
- Testing
- Controlled Ovarian Stimulation + Luteal Phase Support, Hormonal Replacement Therapy programmed artificial cycle, Natural Cycle (NC)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundación IVI
Infertility, Female, Endometriosis
Predicting Endometrial Receptivity for Optimal Reproductive Management
The purpose of this study is to understand why some women are infertile (unable to conceive a child). The investigators hope to learn if an endometrial biopsy after egg retrieval is feasible for detecting biomarkers for…
- Trial name
- PERFORM (NCT04107129)
- Testing
- Endometrial Biopsy, Euploid embryo transfer, Blood sample
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Stanford University
Duration of Estrogen Administration
The Impact of Estrogen Administration Duration in Hormonally Prepared Frozen Embryo Transfer Cycles
This prospective controlled study aimed to investigate the effect of the duration of estrogen (E2) administration prior to progesterone (P) initiation on live birth rates (LBR) in frozen embryo transfer (FET) cycles.
- Trial name
- NCT05825885
- Testing
- E2
- Where
- Turkey (Türkiye)
- Volunteers
- 420 people
- Sponsor
- Akdeniz University
Endometrial Receptivity Diagnosis
Quantitative Identification of Implantation Receptivity by Single Cell Transcriptome Analysis
This project aims to study the endometrial transcriptome at the single cell level in both endometrial native tissue (biopsies) and endometrial fluid.
- Trial name
- NCT03091023
- Testing
- Endometrial Biopsy and endometrial fluid collection
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Igenomix
Adenomyosis, Fibroid Uterus
Fertility Limiting Diseases of Pelvic Organs and Their Influence on Receptivity of Endometrial Cavity: Prospective Clinical Trial
In this project, we will characterize the effects of fertility limiting diseases of pelvic organs on the receptivity of the endometrium.
- Conditions
- Adenomyosis, Fibroid Uterus, Endometriosis
- Trial name
- REAdME (NCT06991595)
- Testing
- cytoreductive resection of adenomyosis, myomectomy, resection of endometriosis, hysteroscopy
- Where
- Czechia
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
The Study Focusses on Improving the Implantation Rate in IVF
Effect of Intrauterine Navigation Using Intrauterine Insemination Catheter for Mock Embryo Transfer Prior to Day 3 Embryo Transfer on Pregnancy Rate: A Pilot Study
Objective: To evaluate the effect of intrauterine navigation using intrauterine insemination catheter (IUI) one day prior to day 3 embryo transfer (ET) on pregnancy rate. Design: Pilot randomized controlled study.
- Trial name
- NCT03358732
- Testing
- endometrial navigation one day before the embyo transfer using IUI catheter ,
- Where
- Saudi Arabia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Endometrial Receptivity
The ERA Test as a Diagnostic Guide for Personalized Embryo Transfer
This project seeks to demonstrate the clinical value of the personalised diagnosis of the endometrial factor in infertility.
- Trial name
- ERA RCT (NCT01954758)
- Testing
- personalized Embryo Transfer (pET), Frozen Embryo Transfer (FET), Fresh Embryo Transfer (ET)
- Where
- 16 sites in Belgium, Brazil and 5 more
- Volunteers
- 569 people
- Sponsor
- Igenomix
Infertility, Female
Exploratory Study Assessing Synchronisation of Egg Sacs With Degarelix
The main purpose of this clinical research study is to investigate if degarelix can synchronise the growth of the egg sacs in the ovaries and if degarelix has any effect on the lining of the womb.
- Trial name
- NCT00434122
- Testing
- Degarelix mid-luteal, 2.5 mg
- Where
- 4 sites in Belgium, Czechia and 1 more
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals