Clinical trials: Endometrioma
Ovarian Endometrioma, Infertility, Female
Surgery and ART For Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of endometrial-like tissue, glands and stroma outside the uterine cavity.
- Trial name
- NCT03717870
- Testing
- Laparoscopic enucleation of ovarian endometrioma., Prolonged pituitary downregulation, Assisted Reproductive Technology (ART)
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Endometrioma
The Impact on Ovarian Reserve of Ovarian Cystectomy Versus Laser Vaporization in the Treatment of Ovarian Endometrioma: a Randomized Clinical Trial
This is a prospective, multicentric (two centers: 1:San Raffaele Scientific institute, Milan, Italy; 2:Jagiellonian University, Collegium Medicum, Cracow, Poland), randomized (1:1) clinical trial that includes patients undergoing…
- Trial name
- Laser (NCT03227640)
- Testing
- stripping technique, CO2 laser (AcuPulse Duo, Lumenis)
- Where
- 2 sites in Italy, Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Endometrioma
Desogestrel for the Preoperative Treatment of Endometrioma Compared With Placebo
Use of the oral desogestrel compared with placebo for preoperative treatment of endometrioma in the patient who underwent to surgery in next 3 months The result will be evaluated on cyst diameter, the associated pain and side…
- Trial name
- NCT04941833
- Testing
- Desogestrel Oral Tablet
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Endometrioma, Endometriosis
Laparoscopic Therapy of Endometrioma: Sclerotherapy vs Cystectomy in Patients With Unfinished Reproductive Plans
The aim of this prospective randomized study is to compare laparoscopic sclerotherapy to cystectomy in following: AMH dynamics, endometrioma recurrence, complications, pregnancy rate, assisted reproduction methods success rate…
- Trial name
- NCT05801523
- Testing
- laparoscopic ethanol sclerotherapy, laparoscopic cystectomy of endometrioma
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Institute for the Care of Mother and Child, Prague, Czech Republic
Ovarian Reserve
Effects of Dienogest and Dienogest Plus Estradiol Valerate in Ovarian Endometrioma
Progesterone resistance in endometriosis is a known fact. The progestin derivatives used in endometriosis cause decidualization and atrophy of ectopic foci.
- Trial name
- NCT03789123
- Testing
- Estradiol valerate/dienogest
- Where
- Turkey (Türkiye)
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Endometriosis
Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy
The study is a prospective, monocentric, randomized controlled, two-armed, pilot-study conducted at Department for Women's Health, Tuebingen, Germany.
- Trial name
- OVAPLAS (NCT07065214)
- Testing
- APC, Lap bipolar forceps
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Erbe Elektromedizin GmbH
Ovarian Endometrioma
Laparoscopic Ovarian Cystectomy Versus Aspiration and Coagulation in Ovarian Endometrioma
The aim of this study is to evaluate the impact of laparoscopic ovarian cystectomy versus aspiration and coagulation on ovarian reserve and pelvic pain in cases of ovarian endometrioma.
- Trial name
- NCT03615352
- Testing
- ovarian cystectomy, ovarian cyst aspiration and coagulation
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Shaimaa Mostafa Mohammed Refaay El shemy
Ovarian Endometrioma, Endometrioma
Estetrol/Drospirenone to Reduce the Average Size of Endometriomas
Endometriosis, a chronic gynecological disorder associated with pain and infertility, is a common condition affecting approximately one in ten women.
- Trial name
- ERASE (NCT05837624)
- Testing
- Estetrol/Drospirenone
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Andrew Zakhari
Ovarian Reserve, Endometriosis
Trial Comparing Preoperative Dienogest Therapy Followed by Surgery vs. Upfront Surgery to Save Ovarian Reserve in Young Women With Ovarian Endometrioma
Randomized phase 2 trial comparing preoperative dienogest therapy followed by surgery vs. upfront surgery to save ovarian reserve in young women with ovarian endometrioma
- Trial name
- DOROSY (NCT02728245)
- Testing
- Dienogest, Surgery
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Ovarian Endometrioma, Ovarian Reserve
Assessment of Ovarian Reserve After Laparoscopic Cystectomy Versus Aspiration/Electrocoagulation in the Treatment of Ovarian Endometrioma
This is a prospective, multicentric (three centers: 1: Shanghai First Maternity and Infant Hospital, Shanghai, China; 2: International Peace Maternity and Child Health Hospital, Shanghai, China, 3: Shanghai Tongji Hospital…
- Trial name
- NCT04151173
- Testing
- laparoscopic aspiration/electrocoagulation, laparoscopic cystectomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
IVF, Endometrioma
Endometrioma Ethanol Sclerotherapy - Prospective Cohort Study Protocol
Ovarian endometriomas are cystic masses lined with endometrial tissue that contains fluid arising from a collection of menstrual debris.
- Trial name
- NCT06971458
- Testing
- Sclerotherapy
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Hillel Yaffe Medical Center
Endometriosis
Relation Between Ethanol Sclerotherapy for Endometrioma Systemic Immune Milieu
Design: Prospective interventional study. 69 women with OE were evaluated clinically and by transvaginal ultrasonography (TUV). AEST procedure was performed and the collected aspirate and pre-procedural blood samples were…
- Trial name
- NCT05470972
- Testing
- Ethanol Injection
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Tanta University
Endometriosis, Dermoid Cyst
Oocyte Freezing for Fertility Preservation in Benign Ovarian Tumors
Benign ovarian cysts are frequent during women's life. They are diagnosed with pelvic pain or fortuitously during an ultra-sonographic exam.
- Conditions
- Endometriosis, Dermoid Cyst, Mucinous Cyst
- Trial name
- OFBOT (NCT03823833)
- Where
- France
- Volunteers
- 82 people
- Sponsor
- University Hospital, Lille
Ovarian Endometrioma, Endometriosis
Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas
The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas.
- Trial name
- ENDO-ARGON (NCT07711743)
- Testing
- Argon Plasma Coagulation
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Endometriosis, Endometrioma
Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)
The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy
- Trial name
- NCT06847685
- Where
- 3 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Ovarian Endometrioma
Impact on Ovarian Reserve of Diode Laser vs Bipolar Coagulation of Endometriomas
Endometriosis is a benign chronic gynaecological disease that affects 10% of women of reproductive age and takes 40% of them to assisted reproduction techniques.
- Trial name
- NCT02350452
- Testing
- Diode laser coagulation, Bipolar coagulation
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Endometrioma
Endometrioma Treatment and Ovarian Function
Ovarian endometriosis (endometrioma) can be a cause of subfertility. According to European Society of Human Reproduction and Embryology (ESHRE) guidelines, surgery for endometrioma is recommended when an endometrioma is more than…
- Trial name
- EnTOF (NCT04452123)
- Testing
- Laparoscopic argon plasma treatment of endometrioma, Laparoscopic stripping of endometrioma and suture/coagulation of the rest of ovary
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Charles University, Czech Republic
Endometriomas
Antimullerian Hormone in Endometriomas
The purpose of this multicenter study is to evaluate the ovarian reserve after alcohol sclerotherapy of endometriomas versus conventional surgery.
- Trial name
- NCT02669628
- Testing
- Surgical technique, Alcohol sclerotherapy
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Hospital Universitari de Bellvitge
Ovarian Endometrioma
Trans-vaginal Aspiration of Small Ovarian Endometrioma. Comparison of Two Different Techniques Before ICSI
women candidate for ICSI and having ovarian endometrioma smaller than 5 cm will be randomized to either transvaginal aspiration alone or transvaginal aspiration follwed by injection of small parts of oxidized regenerated…
- Trial name
- NCT03784404
- Testing
- Transvaginal aspiration, transvaginal aspiration and surgicel injection, Intracytoplasmic sperm injection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Ovarian Reserve
Anti-Mullerian Hormone Changes After Laparoscopic Ovarian Cystectomy for Endometrioma Compared With the Non-ovarian Conditions
This aim of the study is to evaluate the impact of endometrioma and laparoscopic cystectomy on ovarian reserve as measured by serum antimullerian hormone and to study the different effects of levels of serum antimullerian hormone…
- Trial name
- NCT01919333
- Where
- Thailand
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Thammasat University