Clinical trials: Endometriomas
Female Infertility, Endometrioma
NAC Effect on Infertile Women With Endometrioma
Oxidative stress has been investigated as a key factor in the pathogenesis and progression of endometrioma. High follicular fluid ROS levels and serum can be related to negative IVF/ICSI outcomes in infertile women with…
- Conditions
- Female Infertility, Endometrioma, Stress Oxidative
- Trial name
- NCT05460858
- Testing
- N-acetyl cysteine
- Where
- Iran
- Volunteers
- 140 people
- Sponsor
- Royan Institute
Participants' Pain,Quality of Life and Hospital Satisfaction
The Effect of "Adjacent Bed Effect" Induced by Anxiety on the Perioperative Period of Patients With Chocolate Cyst of Ovary
The "adjacent bed effect" caused by anxiety leads to poor recovery of participants after ovarian chocolate cyst surgery, including pain and quality of life, and affects participant satisfaction with the hospital.
- Trial name
- NCT06215482
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Endometriosis Related Infertility
Surgery Before Embryo Transfer in ERROR (Endometrioma Related Reduction in Ovarian Reserve)
This prospective study evaluates the pregnancy results after laparoscopic endometriosis operation in infertile patients with ERROR (endometrioma related reduction in ovarian reserve)
- Trial name
- NCT04233983
- Testing
- Laparoscopic Endometriosis Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uludag University
Dysmenorrhea, Pelvic Pain
Continuous Versus Cyclic Oral Contraceptives for Endometriosis
To evaluate the efficacy of oral contraceptives in a continuous fashion versus the usual cyclic fashion in the recurrence of endometriosis related symptoms and endometriomas following fertility-sparing surgery.
- Conditions
- Dysmenorrhea, Pelvic Pain, Dyspareunia, Endometrioma
- Trial name
- NCT02237131
- Testing
- Oral contraceptives cyclic, Oral contraceptives continuous
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Athens
Sclerotherapy, Endometrioma
Two-session Catheter-directed Sclerotherapy Using Ethanol for Endometrioma
The goal of this clinical trial is to evaluate the safety and clinical outcomes of two-session catheter-directed sclerotherapy (CDS) with 96% ethanol in patients with endometrioma.
- Trial name
- NCT06274086
- Testing
- Two-session catheter-directed sclerotherapy
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Endometriosis Pelvic
ENDOMED: Evaluation of the Evolution of Endometriosis Lesions on Imaging Under Medical Treatment
Endometriosis is a difficult disease to diagnose because the symptoms are varied, unspecific and inconsistent from one patient to another.
- Trial name
- ENDOMED (NCT05722314)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Ovarian Endometrioma
Trans-vaginal Aspiration of Small Ovarian Endometrioma. Comparison of Two Different Techniques Before ICSI
women candidate for ICSI and having ovarian endometrioma smaller than 5 cm will be randomized to either transvaginal aspiration alone or transvaginal aspiration follwed by injection of small parts of oxidized regenerated…
- Trial name
- NCT03784404
- Testing
- Transvaginal aspiration, transvaginal aspiration and surgicel injection, Intracytoplasmic sperm injection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Endometrioma
Endometrioma Sclerotherapy and Ovarian Preservation
A randomised controlled trial assessing ovarian reserve after laparoscopic ethanol sclerotherapy of ovarian endometrioma compared to standard treatment of surgical excision of endometrioma.
- Trial name
- ENDOSAVE (NCT06775769)
- Testing
- Sclerotherapy, Routine Care
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Endometrioma
Effect of Dienogest in Symptomatic Endometrioma in Comparison to Combined Oral Contraceptive Pill.
women of 18-40 years with symptomatic endometrioma (moderate to severe dysmenorrhea with endometrioma(2-5cm),will be allocated into 2 groups-Experimental group (group A) and comparatorgroup( group B).Experimental group:Tab.
- Trial name
- endometrioma (NCT07770594)
- Testing
- Tab.Dienogest 2 mg, Combined oral contraceptive pill (ethinyl estradiol,30mcg+desogestrel,150mcg) tablet
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Mst.Sumyara Khatun
Endometrioma
Effect of Prolonged GnRh Agonists on Results of Intracytoplasmic Sperm Injection (ICSI ) in Endometrioma Patients
Investigators compare ICSI results for endometrioma patients with or without cyst aspiration if more than 5cm \&with or without GnRh agonists for all endometrioma patients
- Trial name
- GnRh (NCT02737800)
- Testing
- endometrioma aspiration, GnRh agonist ( Decapeptyl ), standard long stimulation protocol
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Kasr El Aini Hospital
Endometriosis
Guangdong Provincial Endometriosis Clinical Research Cohort
Endometriosis is a chronic condition that may cause pelvic pain, ovarian cysts, infertility, and recurrent symptoms. This prospective observational cohort study will enroll women aged 18 to 45 years with endometriosis and age…
- Trial name
- NCT07749053
- Where
- China
- Volunteers
- 716 people, healthy volunteers welcome
- Sponsor
- Li Li
Microparticle, Endometriosis
Microparticle Generation After Laparoscopic Surgical Treatment for Endometrioma.
Study objective: To evaluate serial generation of microparticles (MPs) after laparoscopic stripping or CO2 laser vaporization in surgical treatment of patients with ovarian endometrioma (OE).
- Conditions
- Microparticle, Endometriosis, Laparoscopy
- Trial name
- NCT03429881
- Testing
- Stripping versus laser CO2
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Francisco Carmona
Endometrioma, Endometriosis
Laparoscopic Therapy of Endometrioma: Sclerotherapy vs Cystectomy in Patients With Unfinished Reproductive Plans
The aim of this prospective randomized study is to compare laparoscopic sclerotherapy to cystectomy in following: AMH dynamics, endometrioma recurrence, complications, pregnancy rate, assisted reproduction methods success rate…
- Trial name
- NCT05801523
- Testing
- laparoscopic ethanol sclerotherapy, laparoscopic cystectomy of endometrioma
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Institute for the Care of Mother and Child, Prague, Czech Republic
Endometriomas
Antimullerian Hormone in Endometriomas
The purpose of this multicenter study is to evaluate the ovarian reserve after alcohol sclerotherapy of endometriomas versus conventional surgery.
- Trial name
- NCT02669628
- Testing
- Surgical technique, Alcohol sclerotherapy
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Hospital Universitari de Bellvitge
Endometriosis Ovary, Endometrioma
Conservative Endometrioma Surgery
To study which surgical technique offers better results in treating endometriomas in terms of ovarian reserve preservation. The 2 conservatives techniques used are: 1. The combined technique 2.
- Trial name
- BLAST (NCT04151433)
- Testing
- Comparison between 2 different laparoscopic techniques in conservative surgical treatment of endometriomas (both arms are existing and accepted surgical strategies).
- Where
- 4 sites in Belgium
- Volunteers
- 92 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ovarian Endometrioma, Endometrioma
Estetrol/Drospirenone to Reduce the Average Size of Endometriomas
Endometriosis, a chronic gynecological disorder associated with pain and infertility, is a common condition affecting approximately one in ten women.
- Trial name
- ERASE (NCT05837624)
- Testing
- Estetrol/Drospirenone
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Andrew Zakhari
Ovarian Reserve
Anti-Mullerian Hormone Changes After Laparoscopic Ovarian Cystectomy for Endometrioma Compared With the Non-ovarian Conditions
This aim of the study is to evaluate the impact of endometrioma and laparoscopic cystectomy on ovarian reserve as measured by serum antimullerian hormone and to study the different effects of levels of serum antimullerian hormone…
- Trial name
- NCT01919333
- Where
- Thailand
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Endometrioma
Post Operative Continuous Active Combination Sex Steroids for the Prevention of Recurrent Endometrioma Formation
The aim of this study is to determine whether or not continuous combined oral contraceptive pills (COCP's) decrease the risk of recurrent endometrioma formation.
- Trial name
- NCT00999479
- Testing
- Norethindrone acetate and ethinyl estradiol tablets, USP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Endometrioma, Endometriosis Ovary
The Therapy of Large Endometrioma
Endometrioma's prevalence is between 23 and 55%. It causes pelvic pain, decrease fertility and ovarian reserve. Currently, there's no recommendation about large endometrioma's treatment and there's no information on the best…
- Trial name
- ENDOKYSTE (NCT04704115)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Lille
Endometriosis, Endometrioma
PET/MRI for Evaluation of Endometriosis
This study aims to determine if PET/MRI can detect endometriosis and potentially improve upon currently available non-invasive diagnostic capabilities.
- Trial name
- NCT06377553
- Testing
- Radiotracer Injection, Imaging, Rectal Ultrasound Gel Injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital