Clinical trials: Endometriosis, Ovarian, open to volunteers
Endometriosis, Ovarian Reserve
Impact of Surgery for Deep Posterior Endometriosis on Ovarian Reserve (ENDORO)
Endometriosis is a chronic condition typically affecting women of reproductive age and often responsible for chronic pelvic pain and/or infertility. Its prevalence is estimated at 10% of the female population.
- Trial name
- ENDORO (NCT07469007)
- Testing
- pelvic ultrasound, Anti-Müllerian hormone assay, Questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Endometriosis, Endometriosis-Associated Ovarian Carcinoma
A Study Evaluating the Diagnostic Performance of OCS in the Differential Diagnosis of Endometriosis vs. Endometriosis-Associated Ovarian Cancer
Prospectively enroll patients with endometriosis and EAOC who complete the routine diagnostic and treatment process and consent to surgical intervention for OCS testing.
- Trial name
- NCT07029659
- Testing
- Ovarian Cancer Score
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Peking Union Medical College Hospital
Abnormal Uterine Bleeding, Endometriosis
Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic…
- Conditions
- Abnormal Uterine Bleeding, Endometriosis, Uterine Prolapse, Uterine Cancer
- Trial name
- BARHYSTER (NCT06024109)
- Testing
- Closure of the Vaginal Cuff after Total Hysterectomy
- Where
- 2 sites in Germany, Spain
- Volunteers
- 132 people
- Sponsor
- Aesculap AG
Endometriotic Cyst of Ovary
Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian Cystectomy
Endometriosis is a chronic inflammatory disease that affects approximately 10-15% of women of reproductive age. Symptoms include dysmenorrhoea, chronic pelvic pain, dyspareunia and infertility.
- Trial name
- NCT05487092
- Testing
- Letrozole
- Where
- 5 sites in Hong Kong
- Volunteers
- 194 people
- Sponsor
- The University of Hong Kong
Endometrioma, Endometriosis Ovary
The Therapy of Large Endometrioma
Endometrioma's prevalence is between 23 and 55%. It causes pelvic pain, decrease fertility and ovarian reserve. Currently, there's no recommendation about large endometrioma's treatment and there's no information on the best…
- Trial name
- ENDOKYSTE (NCT04704115)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Lille
Infertility Female
Chlordecone Exposure and Female Fertility
Chlordecone is an organochlorine pesticide used in the French West Indies (FWI) from 1972 to 1993 to control the banana root borer.
- Trial name
- KARU-FERTIL (NCT07231510)
- Where
- Guadeloupe
- Volunteers
- 634 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
IVF, Endometrioma
Endometrioma Ethanol Sclerotherapy - Prospective Cohort Study Protocol
Ovarian endometriomas are cystic masses lined with endometrial tissue that contains fluid arising from a collection of menstrual debris.
- Trial name
- NCT06971458
- Testing
- Sclerotherapy
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Hillel Yaffe Medical Center
Endometriosis
Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy
The study is a prospective, monocentric, randomized controlled, two-armed, pilot-study conducted at Department for Women's Health, Tuebingen, Germany.
- Trial name
- OVAPLAS (NCT07065214)
- Testing
- APC, Lap bipolar forceps
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Erbe Elektromedizin GmbH
Endometrioma
Suture of the Ovary After Enucleation of Ovarian Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity.
- Trial name
- SOAVE-1 (NCT03788720)
- Testing
- Suture of the ovarian cortex, No suture of the ovarian cortex
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Endometriosis (Diagnosis), Endometriosis
Combining Ultrasound and Biomarkers to Diagnose Superficial Endometriosis
Endometriosis is a benign gynecological disease characterized by uterine-like cells growing outside the uterus, leading to pain, infertility, and inflammation.
- Trial name
- SPGENDO (NCT05523284)
- Testing
- SonoPODography
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Ovarian Endometrioma, Endometriosis
Histological Evaluation of Dual-wavelength Diode Laser Ablation of Ovarian Endometrioma
Background: Ovarian endometrioma is the most common manifestation of endometriosis and is associated with chronic pelvic pain, infertility, and reduced ovarian reserve.
- Trial name
- DUALENDO (NCT07635199)
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Benign Ovarian Cyst
Comparison of Hemostatic Agent to Suture in Terms of Hemostatic Function and Preservation of Ovarian Function
This study aims to evaluate the efficacy of preservation of ovarian function, hemostasis, and safety of a hemostatic agent versus suturing during laparoscopic ovarian cystectomy for ovarian endometriosis.
- Trial name
- PRAHA-2 (NCT04643106)
- Testing
- Hemostatic agent (EVICEL®) application during laparoscopic ovarian cystectomy, suturing with barbed sutures during laparoscopic ovarian cystectomy
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery
Study Objectives This study aims to investigate the effects of preoperative stellate ganglion block and intraoperative intravenous dexmedetomidine on postoperative sleep disturbance in patients undergoing laparoscopic gynecologic…
- Conditions
- Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus, Endometriosis, Endometrial Cancer
- Trial name
- NCT07860203
- Testing
- DEX 0.2 μg/kg/h., SGB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Catherin Zhang
Ovarian Endometrioma, Endometrioma
Estetrol/Drospirenone to Reduce the Average Size of Endometriomas
Endometriosis, a chronic gynecological disorder associated with pain and infertility, is a common condition affecting approximately one in ten women.
- Trial name
- ERASE (NCT05837624)
- Testing
- Estetrol/Drospirenone
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Andrew Zakhari
Ovarian Cysts, Endometriosis
Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts
We will conduct this study to estimate the effect of laparoscopic cystectomy on ovarian reserve in endometriotic cysts versus non-endometriotic cysts.
- Conditions
- Ovarian Cysts, Endometriosis, Benign Ovarian Cyst, Ovarian Reserve
- Trial name
- NCT07686783
- Testing
- Laparoscopic Ovarian Cystectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Ovarian Endometrioma, Infertility, Female
Surgery and ART For Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of endometrial-like tissue, glands and stroma outside the uterine cavity.
- Trial name
- NCT03717870
- Testing
- Laparoscopic enucleation of ovarian endometrioma., Prolonged pituitary downregulation, Assisted Reproductive Technology (ART)
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Endometriosis, Abdominal Adhesions
The Effect of Temporary Ovarian Suspension to the Abdominal Wall During Laparoscopic Endometriosis Surgery for Adhesion Prevention -A Comparative and Prospective Study
Pelvic adhesions, particularly between ovaries and pelvic sidewall, frequently complicate endometriosis surgery. Despite various interventions, no widely accepted solution exists.
- Trial name
- NCT07087756
- Testing
- laparoscopic ovarian suspension
- Where
- Israel
- Volunteers
- 76 people
- Sponsor
- Carmel Medical Center
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Ovarian Endometrioma, Endometriosis
Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas
The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas.
- Trial name
- ENDO-ARGON (NCT07711743)
- Testing
- Argon Plasma Coagulation
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gynecologic Disease, Gynecologic Cancer
Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology
GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological…
- Conditions
- Gynecologic Disease, Gynecologic Cancer, Endometriosis, Ovarian Cancer
- Trial name
- GynRNA (NCT06392997)
- Testing
- Saliva sample
- Where
- 13 sites in France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- ZIWIG