Clinical trials: Endometriosis, injection or injectable or infusion or IV or syringe or subcutaneous, open to volunteers
- Condition Endometriosis
- Drug or intervention injection OR injectable OR infusion OR IV OR syringe OR subcutaneous
- Status Open to volunteers
Endometriosis
Blood and Tissue Markers for Improving Diagnosis and Prognosis of Endometriosis. (ENDOBIO)
Endometriosis is a chronic, benign, estrogen-dependent disease characterized by endometrial tissue that is implanted outside the uterus into the ovaries, intestines, or peritoneum but also outside the pelvis.
- Trial name
- ENDOBIO (NCT05339451)
- Testing
- Blood biomarkers
- Where
- 3 sites in Sweden
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Endometriosis, Chronic Pelvic Pain Syndrome
Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study
The goal of this randomized controlled trial is to investigate the effect of esketamine versus placebo on the NRS score for chronic pelvic pain.
- Trial name
- EASYlight (NCT06161805)
- Testing
- Esketamine hydrochloride
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Reinier de Graaf Groep
Endometriosis
The Role of FAPI PET-CT in Diagnosing Endometriosis
Patients with suspected endometriosis scheduled for surgery will be identified. They will be asked to participate in a study evaluating the feasibility of FAPI PET-CT in diagnosing endometriosis.
- Trial name
- NCT06792318
- Testing
- FAPI PET-CT
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Ziv Hospital
Endometriosis Pelvic, Endometriosis Ovaries
PRECISION-E2: Teverelix in Women With Endometriosis - Pharmacodynamics, Safety and Precision Medicine Correlates
PRECISION-E2 is a Phase IIa randomized, placebo-controlled study evaluating the pharmacodynamic profile, safety and tolerability of teverelix in premenopausal women with moderate-to-severe pain associated with endometriosis in…
- Conditions
- Endometriosis Pelvic, Endometriosis Ovaries, Premenopausal, Endometriosis (Diagnosis)
- Trial name
- NCT07914062
- Testing
- Teverelix DP
- Volunteers
- 84 people
- Sponsor
- Antev Ltd.
Endometriosis, Ozone Therapy
Ozone Therapy for Women With Endometriosis
To evaluate the action of ozone therapy as an adjuvant treatment in patients with endometriosis. Secondary Objective: To evaluate the efficacy of ozone therapy for pelvic analgesia in women with endometriosis; To compare the…
- Conditions
- Endometriosis, Ozone Therapy, Thermography
- Trial name
- NCT07035522
- Testing
- Ozone therapy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal do Paraná
Endometriosis
Diagnosis of Pelvic Endometriosis in MRI
Purpose： Evaluate the feasibility of R2 star multiple fast gradient recalled echo (R2*MFGRE) imaging in the diagnosis of pelvic endometriosis.
- Trial name
- NCT06157528
- Testing
- Magnetic resonance imaging
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhenshen Ma
Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery
Study Objectives This study aims to investigate the effects of preoperative stellate ganglion block and intraoperative intravenous dexmedetomidine on postoperative sleep disturbance in patients undergoing laparoscopic gynecologic…
- Conditions
- Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus, Endometriosis, Endometrial Cancer
- Trial name
- NCT07860203
- Testing
- DEX 0.2 μg/kg/h., SGB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Catherin Zhang
Endometriosis
Predicting the Pain Outcome of Surgery for Endometriosis
This study aims to determine whether the investigators can predict who will get benefit in terms of their pain from surgery for more severe forms of endometriosis.
- Trial name
- PrePOSE (NCT07313345)
- Testing
- Surgical treatment of endometriosis
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Oxford
Endometriosis
Perioperative Esketamine Safety and Efficacy in Reducing Postoperative ENDometriosis PAIN (the ENDPAIN Trial): a Randomized Controlled Trial.
Endometriosis is a chronic condition affecting approximately 10% of women. It is frequently associated with persistent or recurrent pelvic and abdominal pain.
- Trial name
- ENDPAIN (NCT07881562)
- Testing
- Esketamine
- Volunteers
- 1,000 people
- Sponsor
- Region Skane
Endometriosis
Phase Ia Trial of HHK001 Compared With Enantone in Patients With Endometriosis
The goal of this clinical trial is to find out how the study drug HHK001 compares to Enantone (an approved treatment for endometriosis) when given as a single 3.75 mg injection to participants with endometriosis.
- Trial name
- NCT07755956
- Testing
- HHK001, Enantone
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Zhuhai Huahaikang Pharmaceutical Technology Co., Ltd.
Endometriosis, Deep Infiltrating Endometriosis
Prospective Trial of [18F]AlF-FAPI-74 for PET Imaging of Fibroblast Activation Protein in Patients With Endometriosis
The goal of this clinical trial is to learn whether [18F]AlF-FAPI-74 PET/CT can help detect endometriosis in adult women who are already scheduled for laparoscopy due to suspicion of deep infiltrating endometriosis or superficial…
- Conditions
- Endometriosis, Deep Infiltrating Endometriosis, Women, Superficial Peritoneal Endometriosis
- Trial name
- EM-FAPI (NCT07876648)
- Testing
- [18F]AlF-FAPI-74 PET/CT
- Where
- Belgium
- Volunteers
- 64 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Deep Infiltrating Endometriosis (DIE), Infertility
Ultra-Long GnRH-a Pretreatment for FET Outcomes in Patients With Deep Infiltrating Endometriosis
Deep infiltrating endometriosis is a severe form of endometriosis that may reduce fertility and negatively affect pregnancy outcomes after assisted reproductive treatment.
- Trial name
- DIE-GnRHa-FET (NCT07696351)
- Testing
- Triptorelin (GnRH agonists), Hormone Replacement Therapy (HRT)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Li-jun Ding
Endometriosis, Endometrioma
PET/MRI for Evaluation of Endometriosis
This study aims to determine if PET/MRI can detect endometriosis and potentially improve upon currently available non-invasive diagnostic capabilities.
- Trial name
- NCT06377553
- Testing
- Radiotracer Injection, Imaging, Rectal Ultrasound Gel Injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Thyroid Pathology, Head and Neck Cancer (H&N)
FAPI PET Imaging - An Exploratory Study
This study is testing a new imaging tracer called [18F]FAPI-74 with PET scans. Researchers want to find out how well this tracer shows certain diseases in the body, including several types of cancer and some non-cancer conditions…
- Conditions
- Thyroid Pathology, Head and Neck Cancer (H&N), Sinonasal Tract Tumor, Sarcoidosis
- Trial name
- FAPIPET (NCT07705074)
- Testing
- [18F]FAPI-74 PET/CT
- Where
- 5 sites in Switzerland
- Volunteers
- 770 people
- Sponsor
- Martin Huellner
Endometriosis
Imaging of Endometriosis With Total-body PET-CT (PET-Endo)
Endometriosis is a disease that affects 1 in 10 women and is associated with debilitating pain and infertility. Endometriosis is where cells similar to those lining the womb (the 'endometrium') grow elsewhere in the body, forming…
- Trial name
- PET-Endo (NCT07523997)
- Testing
- PET/CT, PET/MRI, Buscopan 20 MG/ML Injectable Solution
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Endometriosis, Adenomyosis
Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis
Women suffering from endometriosis and/or adenomyosis may also suffer from infertility. GnRH agonist injection could improve implantation and therefore increase the pregnancy rate in these patients.
- Conditions
- Endometriosis, Adenomyosis, Infertility, Female
- Trial name
- DECATEC (NCT04356664)
- Testing
- GnRH agonist
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Hopital Foch
Endometriosis, Infertility Unexplained
Endometriosis and Peritoneal Dysbiosis
Endometriosis is a complex clinical syndrome that impairs many aspects of a woman's life, characterized by a chronic estrogen-dependent inflammatory process, mainly affecting the pelvic organs, with ectopic presence of tissue…
- Trial name
- NCT05824819
- Testing
- Next Generation Sequencing (NGS)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Jagiellonian University
Endometriosis, Rectum, Endometriosis of Colon
The (Cost-)Effectiveness of Surgical Excision of Colorectal Endometriosis Compared to ART Treatment Trajectory
To goal of this study is to determine whether laparoscopic resection of colorectal endometriosis results in an increased cumulative live birth rate (CLBR) both spontaneous and after ART (including in vitro fertilization (IVF) or…
- Conditions
- Endometriosis, Rectum, Endometriosis of Colon, Subfertility, Female
- Trial name
- TOSCA (NCT05677269)
- Testing
- Laparoscopic excision of endometriosis, including colorectal endometriosis, In vitro fertilisation or intracytoplasmic sperm injection
- Where
- 10 sites in Netherlands
- Volunteers
- 339 people
- Sponsor
- Leiden University Medical Center
Endometriosis
Evaluate the Efficacy and Safety of HMI-115 in Women With Moderate to Severe Endometriosis-associated Pain
A phase 3 study to evaluate the efficacy and safety of HMI-115 in women with moderate to severe endometriosis-associated pain over a 24-week treatment period and a 28-week extension
- Trial name
- NCT07318688
- Testing
- HMI-115
- Where
- 5 sites in China
- Volunteers
- 540 people
- Sponsor
- Hope Medicine (Nanjing) Co., Ltd
Fibrin Blood Clot, Infertility, Female
Ovarian Hyperstimulation and Fibrin Clot Properties.
The impact evaluation of ovarian hyperstimulation on coagulation and fibrinolysis in infertile women. Comparative analysis between different ovarian stimulation protocols on thrombin formation and efficiency of fibrinolysis in…
- Conditions
- Fibrin Blood Clot, Infertility, Female, Endometriosis
- Trial name
- NCT04166825
- Testing
- fibrin clot properties
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Jagiellonian University