Clinical trials: Endometriosis Ovary
Endometrioma, Ultrasound Therapy; Complications
Effect of Alcohol Sclerotherapy on Pelvic Pain and Quality of Life in Women With Ovarian Endometriosis
The goal of this clinical trial is to evaluate whether ultrasound-guided alcohol sclerotherapy can improve pelvic pain and quality of life in women aged 18 to 45 diagnosed with ovarian endometriomas, compared to expectant…
- Conditions
- Endometrioma, Ultrasound Therapy; Complications, Quality of Life, Pelvic Pain
- Trial name
- ESCOMA (NCT06955221)
- Testing
- Ultrasound-guided aspiration and alcohol sclerotherapy
- Where
- 27 sites in Spain
- Volunteers
- 288 people
- Sponsor
- Hospital Universitari de Bellvitge
Endometriosis, Endometriosis Ovary
Pretreatment With Dienogest in Women With Endometriosis Undergoing in Vitro-fertilization After a Previous Failed Cycle
It is generally assumed that the major causes of in vitro fertilization (IVF) failure in women with endometriosis are diminished ovarian reserve, impaired endometrial receptivity and low quality of embryos.
- Conditions
- Endometriosis, Endometriosis Ovary, IVF
- Trial name
- NCT04306276
- Testing
- Dienogest 2 MG
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Ospedale Policlinico San Martino
Endometriosis Ovary
Changes in Serum antimüllerian Hormone Levels in Patients 3 and 12 Months After Endometrioma Sclerotherapy
Endometriosis affects 6-10% of women in childbearing age. It is a heterogeneous disease with three different forms: superficial endometriosis (peritoneal), ovarian endometrioma and deep pelvic endometriosis (subperitoneal).
- Trial name
- ENDOPAL AMH (NCT04461899)
- Testing
- Blood test
- Where
- 3 sites in France
- Volunteers
- 53 people
- Sponsor
- Hospices Civils de Lyon
Ovarian Endometrioma, Ovarian Endometriosis
Evaluating Ovarian Reserve After Conventional Laparoscopy Versus Robotic Surgery for Bilateral Endometrioma
The aim of this study is to perform a randomized study investigating AMH recovery comparing robot-assisted laparoscopy and conventional laparoscopy in patients with bilateral ovarian endometrioma.
- Trial name
- NCT05357924
- Testing
- robotic-assisted laparoscopy, Conventional laparoscopy
- Where
- Austria
- Volunteers
- 104 people
- Sponsor
- Medical University of Vienna
Endometriosis, Endometriosis Ovary
Menstrual Blood Proteomic Profile in Women With Endometriosis (PROTEO-ENDO) Study
In this prospective case control study a total of 66 women (33 women with endometriosis) and (33 healthy women) will be recruited.
- Conditions
- Endometriosis, Endometriosis Ovary, Endometriosis-related Pain
- Trial name
- PROTEO-ENDO (NCT06214260)
- Testing
- Peripheral blood sample, Menstrual Blood sample
- Where
- Hong Kong
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Endometrioma
Suture of the Ovary After Enucleation of Ovarian Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity.
- Trial name
- SOAVE-1 (NCT03788720)
- Testing
- Suture of the ovarian cortex, No suture of the ovarian cortex
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Infertility Female
Chlordecone Exposure and Female Fertility
Chlordecone is an organochlorine pesticide used in the French West Indies (FWI) from 1972 to 1993 to control the banana root borer.
- Trial name
- KARU-FERTIL (NCT07231510)
- Where
- Guadeloupe
- Volunteers
- 634 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Endometriosis Ovaries, Infertility, Female
Assessment of Telomerase Activity in Endometrial Tissue and Serum in Endometriosis Patients
The goal of the study was the detection of telomerase activity in eutopic, ectopic endometrial tissue and in peripheral blood and finding the correlation between the telomerase activity and clinic findings.
- Trial name
- NCT02984774
- Testing
- Cystectomy, Endometrial sampling, Peripheric blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Endometriosis, Endometriosis Ovary
A Multicenter, Observational Clinical Study of Dydrogesterone
The objective of this study was to investigate the efficacy and safety of dydrogesterone in the long-term management of ovarian endometriosis cyst after surgery.
- Trial name
- NCT05976529
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Guangdong Women and Children Hospital
Endometriosis Ovary
Comparing the Safety and Efficacy in the Use of Hormonal Therapy on Endometriosis Patients After Conservative Surgery
The goal of this clinical trial is to compare safety and efficacy in endometriosis patient after conservative surgery. The main question[s] it aims to answer are: 1. Health-related quality of life (HRQoL) 2. VAS score 3.
- Trial name
- ENDOSafe (NCT06145438)
- Testing
- Dienogest, Depo Medroxyprogesterone acetate, Leuprolide (as Leuprolide Acetate)
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Diponegoro
Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary
Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Full conditioning of the peritoneal cavity during laparoscopic surgery will decrease post-operative pain, inflammation and adhesion formation.
- Conditions
- Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary, Fibroid/Myoma (Uterus/Cervix)
- Trial name
- NCT01344486
- Testing
- full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Secondary Dysmenorrhea, Dysmenorrhea
Iyengar Yoga Therapy for Dysmenorrhea and Endometriosis
The purpose of this clinical trial is to look at the effectiveness of prescribing yoga classes to patients with dysmenorrhea (irregular or painful periods), or other menstrual disorders on patients' self reported pain and quality…
- Conditions
- Secondary Dysmenorrhea, Dysmenorrhea, Dysmenorrhea Secondary, Polycystic Ovary Syndrome
- Trial name
- NCT03784976
- Testing
- Iyengar Yoga Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Illinois at Urbana-Champaign
Endometriosis
PGL5001 Proof of Concept Study in Inflammatory Endometriosis
This is a prospective, three-part (Part A1, Part A2 and Part B),Phase II study investigating the efficacy, safety, pharmacokinetics and pharmacodynamics of the JNK inhibitor PGL5001 orally administered for up to 5 months with…
- Trial name
- JADE (NCT01630252)
- Testing
- PGL5001
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- PregLem SA
Stroke, Spinal Cord Diseases
Use of tDCS Stimulation in Neurological and Gynaecological Conditions
The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients.
- Conditions
- Stroke, Spinal Cord Diseases, Nerve Root Disorder, Endometriosis
- Trial name
- tDCS (NCT06891690)
- Testing
- tDSC stimulation
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Endometrioma, Ruptured Endometrioma
Comparison of Operated Ruptured and Non-ruptured Endometriomas
Ruptured endometrioma cases were compared with unruptured endometrioma cases.
- Conditions
- Endometrioma, Ruptured Endometrioma, Endometriosis Ovary
- Trial name
- RupturedOMA (NCT05348070)
- Testing
- Laparoscopy/Laparotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 181 people
- Sponsor
- EZH EAH
Endometriosis
Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis
Does a combination of Arimidex and Zoladex make endometriomas shrink and how is the following IVF outcome
- Trial name
- NCT00286351
- Testing
- Combined treatment with Arimidex and Zoladex before IVF
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Endometrioma, Ovarian Endometriosis
Evaluation of Ovarian Reserve and Recurrence Rate After DWLS Diode Laser OMA Vaporization
PURPOSE OF THE STUDY The study aims to evaluate the effectiveness of the Dual Wavelength Laser System (DWLS) diode laser on the treatment of endometrioma (OMA), with ablation and vaporization of the cystic capsule without…
- Conditions
- Endometrioma, Ovarian Endometriosis, Ovarian Endometrioma
- Trial name
- OMAlaser (NCT06219044)
- Testing
- laparoscopic endometrioma laser vaporization
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Endometrioma, Endometriosis Ovary
The Therapy of Large Endometrioma
Endometrioma's prevalence is between 23 and 55%. It causes pelvic pain, decrease fertility and ovarian reserve. Currently, there's no recommendation about large endometrioma's treatment and there's no information on the best…
- Trial name
- ENDOKYSTE (NCT04704115)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Lille