Clinical trials: Endometriosis Pelvic
Endometriosis
Impact of Magnetic Stimulation on Pain in Endometriosis Patients
Many women with endometriosis still experience pain despite surgical and medical treatment. Over-the-counter painkillers are usually helpful in alleviating this pain.
- Trial name
- NCT07265687
- Testing
- Magnetic stimulation
- Volunteers
- 30 people
- Sponsor
- Kantonsspital Winterthur KSW
Endometriosis, Chronic Pelvic Pain
Ketamine in Central Sensitization
The purpose of this research study is to see if ketamine infusion during surgery can decrease pain after surgery. Ketamine is a medication commonly used as part of anesthesia during surgery and is approved by the US FDA.
- Trial name
- NCT07182032
- Testing
- ketamine
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Uterine Fibroids, Endometriosis
AMH Levels Change During Treatment With GnRh Agonist
To evaluate the variation of AMH levels in women undergoing treatment with GnRHa, and to assess whether this variation correlates with changes in the antral and pre-antral follicle ultrasonographic count (AFC).
- Conditions
- Uterine Fibroids, Endometriosis, Endometriosis of Uterus, Pelvic Pain
- Trial name
- NCT02086279
- Testing
- GnRH analogue
- Where
- Italy
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Endometriosis, Dysmenorrhea
Effect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant Therapy
The goal of this clinical trial is to investigate the effect of propolis administration on dysmenorrhea in endometriosis patient.
- Trial name
- NCT05770297
- Testing
- Propolis
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pelvic Pain Associated With Refractory Endometriosis
A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis
The purpose of this study is to determine efficacy, safety, tolerability and pharmacokinetics of multiple doses of BGS649 with concurrent daily administration of combined oral contraception in patients with refractory…
- Trial name
- NCT01116440
- Testing
- BGS649
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 27 people
- Sponsor
- Mereo BioPharma
Endometriosis (Diagnosis)
Comparison of Elagolix and OCPs in Reducing Endometriosis Associated Pelvic Pain
This study is designed to provide direct evidence on the relative effectiveness and safety of Elagolix versus OCPs, helping physicians make more tailored treatment decisions.
- Trial name
- NCT07532876
- Testing
- Elagolix, Oral Contraceptive (OC)
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Pak Emirates Military Hospital
Endometriosis, Post Operative Pain
The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6 mg/kg) of ketamine versus placebo (saline) on postoperative pain and pain on adult female chronic pelvic pain…
- Trial name
- NCT05229653
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Endometriosis, Dysmenorrhea
Pertubation With Lignocaine in Endometriosis
Endometriosis is a disease of unknown aetiology that can cause severe dysmenorrhea. An altered immune system with elevated levels of cytokines in the peritoneal fluid as well as increased density of nerve fibres, might explain…
- Trial name
- PLEASE (NCT01329796)
- Testing
- Lignocaine, Ringers Solution
- Where
- 3 sites in Sweden
- Volunteers
- 42 people
- Sponsor
- Isifer AB
Endometriosis, Rectum, Endometriosis of Vagina
Rectal Water-contrast Transvaginal Ultrasonography Versus Sonovaginography for the Diagnosis of Posterior Deep Pelvic Endometriosis
As the surgical treatment of posterior deep endometriosis may be challenging for surgeons and carry significant risks for patients, preoperative assessment of the location, characteristics and presence of nodules of posterior…
- Conditions
- Endometriosis, Rectum, Endometriosis of Vagina, Endometriosis Rectovaginal Septum, Endometriosis Pelvic
- Trial name
- NCT04296760
- Testing
- Rectal water-contrast transvaginal ultrasonography, Sonovaginography
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fabio Barra
Chronic Pelvic Pain, Endometriosis
Endometriosis Biomarker Discovery Study
This is a prospective, Single time point, discovery study intending to identify biomarkers that can differentiate endometriosis from other underlying reasons for pelvic pain.
- Trial name
- EMBARK (NCT03272360)
- Sponsor
- Myriad Genetic Laboratories, Inc.
Endometriosis, Chronic Pain
Evaluation of Yoga and Conventional Physical Exercise for Pain and Quality of Life in Women With Endometriosis: A Randomized Clinical Trial
two-arm randomized parallel-group trial comparing an 8-week online yoga program versus a conventional physical exercise program.
- Conditions
- Endometriosis, Chronic Pain, Dysmenorrhea, Dyspareunia
- Trial name
- NCT07424859
- Testing
- YOGA, physical exercise
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Chronic Pelvic Pain, Endometriosis
Novel Web-based, Self-directed Intervention for Chronic Pelvic Pain
The study is being completed to evaluate the effectiveness of a web-based, self-management program for patients with Chronic Pelvic Pain (CPP).
- Trial name
- NCT06352840
- Testing
- My Pelvic Plan Website, Control Group website
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Michigan
Dysmenorrhea
Efficacy and Safety, Long-Term Study of NPC-01 to Treat Dysmenorrhea Associated With Endometriosis
The purpose of this long-term study is to determine whether NPC-01 is effective in the treatment of dysmenorrhea associated with endometriosis.
- Trial name
- NCT00902746
- Testing
- NPC-01
- Volunteers
- 149 people
- Sponsor
- Nobelpharma
Endometriosis, Endometriosis (Diagnosis)
Impact of the Antihistamine Desloratadine on the Quality of Life and Dysmenorrhea in Patients With Endometriosis
Endometriosis is a chronic inflammatory disease affecting approximately 10% of women in their reproductive years. It is characterized by the presence of endometrial-like tissue outside the uterine cavity.
- Conditions
- Endometriosis, Endometriosis (Diagnosis), Endometriosis and Dysmenorrhea, Endometriosis Associated Pelvic Pain
- Trial name
- NCT07821320
- Testing
- Desloratadine
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Endometriosis
Whole-Body Cryotherapy as a Non-Pharmacological Treatment to Reduce Chronic Pelvic Pain and Improve Quality of Life in People With Endometriosis
The aim of this study is to investigate whether whole-body cryotherapy (a brief exposure to very cold temperatures) can help reduce pain and improve quality of life in people living with endometriosis, and whether it may…
- Trial name
- CHILL-Endo (NCT07603960)
- Testing
- Whole-Body Cryotherapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Cervical Carcinoma, Endometrial Carcinoma
Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer
This early phase I trial compares the side effects between patients treated with proton radiation therapy versus intensity modulated radiation therapy after surgery for the treatment of endometrial or cervical cancer.
- Conditions
- Cervical Carcinoma, Endometrial Carcinoma, Endometriosis, Pelvic Inflammatory Disease
- Trial name
- NCT04567771
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Radiation Therapy
- Where
- 3 sites in United States
- Volunteers
- 121 people
- Sponsor
- Mayo Clinic
Endometriosis, Chronic Pelvic Pain Syndrome
Identify a Specific Immune Profile in Patients With Chronic Pelvic Pain Resistant to First-line Treatments by Measuring Th1, Th2, Th17, and Treg Cytokines Produced After Non-specific Functional Cell Stimulation - ImmunoCPP
Chronic pelvic pain (CPP) affects more than one in four women. An immune imbalance in the Th1/Th2 balance has been reported in multiple CPP situations, particularly in patients with endometriosis, but with mixed results.
- Trial name
- ImmunoCPP (NCT07429773)
- Testing
- Immune profile
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Endometriosis
Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Adults With Moderate to Severe Endometriosis-Associated Pain
A randomized study evaluating the continued safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in pre-menopausal women.
- Trial name
- NCT01760954
- Testing
- Elagolix
- Volunteers
- 506 people
- Sponsor
- AbbVie
Endometriosis
Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain
The primary objective of this extension study is to assess the maintenance of efficacy of linzagolix administered orally once daily for up to an additional 6 months (for up to 12 months of treatment in total) in women who have…
- Trial name
- EDELWEISS 5 (NCT04372121)
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 25 sites in United States, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Metrorrhagia, Menorrhagia
Surgical Success After Laparoscopic vs Abdominal Hysterectomy
The purpose of the proposed pilot study is to investigate the effectiveness, cost, safety, and long-term impact on quality of life of laparoscopic hysterectomy (LH) in relation to abdominal hysterectomy (AH) for the treatment of…
- Conditions
- Metrorrhagia, Menorrhagia, Leiomyoma, Adenomyosis
- Trial name
- NCT01793584
- Testing
- Laparoscopic hysterectomy, Abdominal hysterectomy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center