Clinical trials: Endometriosis Pelvic
Endometriosis, Chronic Pelvic Pain
A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirmed Endometriosis and the Impact on the Disease or Symptom Progression.
This study will describe historic, current, and evolving treatment pathways, treatments, and interventions in women with a suspected or confirmed diagnosis of endometriosis in order to better understand the impact of early…
- Conditions
- Endometriosis, Chronic Pelvic Pain, Dysmenorrhea
- Trial name
- NCT04140175
- Where
- 117 sites in United States
- Volunteers
- 291 people
- Sponsor
- AbbVie
Endometriosis
A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Participants With Moderate to Severe Endometriosis-Associated Pain
The objective of this study is to evaluate safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in adult premenopausal female participants including the safety and efficacy of…
- Trial name
- NCT03213457
- Testing
- Estradiol/Norethindrone Acetate, Elagolix
- Where
- 197 sites in United States, Canada and 1 more
- Volunteers
- 681 people
- Sponsor
- AbbVie
Endometriosis
Safety and Efficacy Study to Evaluate Proellex in the Treatment of Premenopausal Women With Symptomatic Endometriosis
The purpose of this study is to determine whether Proellex is safe and effective for the treatment of symptomatic endometriosis.
- Trial name
- NCT00556075
- Testing
- Proellex 25 mg, Proellex 50 mg
- Where
- 17 sites in United States
- Volunteers
- 67 people
- Sponsor
- Repros Therapeutics Inc.
Endometriosis
ENDO1000 - A UK-wide Endometriosis Research Project
Approximately 1.5 million people in the UK, and 200 million globally live with endometriosis, and it is estimated to affect 1 in 10 women of reproductive age.
- Trial name
- NCT07240883
- Testing
- Sample and data collection
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- University of Edinburgh
Endometriosis
Degarelix in the Treatment of Endometriosis Recurrence
The long acting GnRH antagonist degarelix will be tested for the treatment of women with endometriosis recurrence compared with classical GnRH analog treatment.
- Trial name
- NCT01712763
- Testing
- degarelix, Leuprolide Acetate 11.25 MG/ML (Enantone 11,25)
- Where
- 3 sites in Albania, Bulgaria and 1 more
- Volunteers
- 360 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Endometriosis
Diffusion Endometriosis MRI to Detect and Quantify Symptomatic Neurological Impairment in Pelvic Endometriosis
This research focuses on evaluating the ability of diffusion tensor imaging (DTI) to detect nerve damage in pelvic endometriosis.
- Trial name
- TENDANSE (NCT06908655)
- Testing
- MRI
- Where
- 3 sites in France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometriosis-related Pain, Endometriosis
Enriched Environments in Endometriosis
The investigators propose to conduct a randomized behavioral trial that will produce a clinically useful multi-level integrative medicine model to be used in stress- and inflammation-related disorders that can easily be…
- Conditions
- Endometriosis-related Pain, Endometriosis, Pelvic Pain, Quality of Life
- Trial name
- NCT04179149
- Testing
- Environmental enrichment
- Where
- Puerto Rico
- Volunteers
- 56 people
- Sponsor
- Ponce Medical School Foundation, Inc.
Endometriosis
A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Women With Endometriosis.
The objective of this study is to determine the safety and efficacy of 3 asoprisnil doses (0.5 mg, 1.5 mg, and 5.0 mg) for 12 weeks in women with endometriosis.
- Trial name
- NCT00160433
- Testing
- Asoprisnil
- Volunteers
- 131 people
- Sponsor
- Abbott
Gynecological Surgeries
A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries(SPiM-RWS-GYN)
Study name：A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries Study purpose：This clinical trial is a real-world study to evaluate the clinical…
- Trial name
- NCT06082011
- Testing
- da Vinci SP Surgical System
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Ruijin Hospital
Intrauterine Device Expulsion, Adenomyosis, Endometriosis
Clinical Observation of Hysteroscopy-Assisted Placement of Handmade Frameless GyneFix-LNG-IUS (Retrospective Cohort)
This is a retrospective self-controlled observational study. We evaluated the safety and efficacy of a handmade frameless levonorgestrel-releasing intrauterine system (GyneFix-LNG-IUS) in patients at high risk of IUD expulsion.
- Conditions
- Intrauterine Device Expulsion, Adenomyosis, Endometriosis, Menorrhagia, Dysmenorrhea, Abnormal Uterine Bleeding
- Trial name
- Gyne-LNG-IUS (NCT07518693)
- Testing
- Handmade Frameless GyneFix-LNG-IUS
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Yu Wang
Endometriosis
The Effect of Dienogest vs. Norethindrone Acetate Treatment in Endometriosis
This randomized controlled study aims to investigate the efficiency of medical treatment modalities in endometriosis patients. The study protocol involves two arms. (Dienogest Group and Noretindrone Acetate Group).
- Trial name
- DINE (NCT05476172)
- Testing
- Dienogest Pill, Norethindrone Acetate
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Uludag University
Endometriosis, Chronic Pelvic Pain
Pelvic Floor Physical Therapy and Exercise for Women With Endometriosis and Chronic Pelvic Pain
Endometriosis is a chronic gynecological condition that can cause persistent pelvic pain, painful menstruation, painful sexual intercourse, and reduced quality of life.
- Trial name
- NCT07733583
- Testing
- Pelvic Floor Physical Therapy, Physical Exercise
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Endometriosis
A Study to Evaluate Safety and Efficacy of Elagolix in Participants With Endometriosis With Associated Moderate to Severe Pain
This is a Phase 3, dose-escalation study designed to evaluate the safety and efficacy of both elagolix alone and elagolix plus estradiol/norethindrone acetate (E2/NETA) over 24 months in the management of endometriosis with…
- Trial name
- NCT03343067
- Testing
- elagolix, estradiol/norethindrone acetate (E2/NETA)
- Where
- 37 sites in United States
- Volunteers
- 11 people
- Sponsor
- AbbVie
Endometrioma, Ultrasound Therapy; Complications
Effect of Alcohol Sclerotherapy on Pelvic Pain and Quality of Life in Women With Ovarian Endometriosis
The goal of this clinical trial is to evaluate whether ultrasound-guided alcohol sclerotherapy can improve pelvic pain and quality of life in women aged 18 to 45 diagnosed with ovarian endometriomas, compared to expectant…
- Conditions
- Endometrioma, Ultrasound Therapy; Complications, Quality of Life, Pelvic Pain
- Trial name
- ESCOMA (NCT06955221)
- Testing
- Ultrasound-guided aspiration and alcohol sclerotherapy
- Where
- 27 sites in Spain
- Volunteers
- 288 people
- Sponsor
- Hospital Universitari de Bellvitge
Endometriosis, Chronic Pelvic Pain
Ketamine in Central Sensitization
The purpose of this research study is to see if ketamine infusion during surgery can decrease pain after surgery. Ketamine is a medication commonly used as part of anesthesia during surgery and is approved by the US FDA.
- Trial name
- NCT07182032
- Testing
- ketamine
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Endometriosis
Feasibility and Potential Aids of Intra-operative Endo-vaginal Ultrasound When Performing Rectal Shaving for Endometriosis
The protocol of this study consists in the inclusion of patients with endometriosic rectal involvement with a scheduled intervention.
- Trial name
- ECHOENDO (NCT05499884)
- Testing
- Endovaginal ultrasound
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Lille
Pelvis Pain Chronic, Endometriosis of Uterus
Functional Brain Imaging and Psychological Testing in Women With Chronic Pelvic Pain
Functional magnetic resonance imaging in women with chronic pelvic pain using arterial spin labelling, functional connectivity, diffusion tensor imaging and magnetic resonance spectroscopy.
- Trial name
- NCT02160483
- Testing
- Functional magnetic resonance imaging
- Where
- Singapore
- Sponsor
- KK Women's and Children's Hospital
Leiomyoma, Pelvic Organ Prolapse
The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures
This study evaluates the influence of the transversus abdominis plane block on the intensity of postoperative pain and the concentration of proinflammatory and pain factors after hysterectomy by laparotomy.
- Conditions
- Leiomyoma, Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Chronic Pain
- Trial name
- TAP (NCT04172272)
- Testing
- Systemic multimodal analgesia administered intravenously, Transversus abdominis plane block (TAP block), Combined transversus abdominis plane block (TAP block) with systemic multimodal analgesia administered intravenously
- Where
- 2 sites in Croatia
- Volunteers
- 75 people
- Sponsor
- General Hospital Pula
Endometriosis, Chronic Pelvic Pain
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus.
- Trial name
- NCT00073801
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Endometriosis
Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain
Endometriosis is a painful disorder of the uterus affecting 6-10% of women of childbearing age. Endometriosis affects daily activities, social relationships, sexuality and sexual activity, and mental health.
- Trial name
- ELARIS EM-COC (NCT04333576)
- Testing
- Elagolix, Combined Oral Contraceptive
- Where
- 179 sites in United States, Puerto Rico
- Volunteers
- 800 people
- Sponsor
- AbbVie