Clinical trials: Endoscopic Assessment
Cholangiocarcinoma, Pancreatic Cancer
Endoscopic Bipolar Radiofrequency Probe (ENDOHPB) in the Management of Unresectable Bile Duct and Pancreatic Cancer
The purpose of this study is to assess safety and ability of the endoscopic bipolar radiofrequency ablation (RFA) probe (ENDOHPB) to produce an improvement in the management of cancer of the bile duct or the pancreatic duct.
- Trial name
- NCT01303159
- Testing
- Endoscopic bipolar radiofrequency probe (ENDOHPB)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Weill Medical College of Cornell University
Gastrointestinal Injury, Ischemic Heart Disease
Mono- Versus Dual antiPlatelet Therapy During 6-12 Months After New Generation Drug Eluting Stent Implantation
Long-term DAPT is recommended after percutaneous coronary intervention (PCI) in patients with coronary artery disease. However, antiplatelet therapy may have adverse consequences, the most common of which is gastrointestinal…
- Trial name
- OPT-PEACE (NCT03198741)
- Testing
- Aspirin + clopidogrel, Clopidogrel monotherapy, Aspirin monotherapy
- Where
- China
- Volunteers
- 783 people
- Sponsor
- Shenyang Northern Hospital
Chronic Liver Disease, Esophageal Varices
Blood Ammonia as Predictor for Esophageal Varices and Risk of Bleeding
Assessment of blood ammonia level as a non-invasive predictor for presence of EV and risk of bleeding
- Trial name
- EV (NCT03212872)
- Testing
- Endoscopy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Acute Pancreatitis (AP)
ENDoscopic Assessment in Acute PANcreatitis Study (ENDOPAN Study)
This is a prospective observational cohort study designed to evaluate early upper gastrointestinal endoscopic findings in adult patients hospitalized with acute pancreatitis.
- Trial name
- NCT07714850
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jan Kochanowski University
Pancreatic Disease, Pancreatic Cancer
EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope
This is a randomized trial to compare the standard echoendoscope with the newly developed EndoSound Visual System in the evaluation of lesions in the gastrointestinal tract.
- Conditions
- Pancreatic Disease, Pancreatic Cancer, Pancreatic Cyst, Gastrointestinal Tumor
- Trial name
- NCT06340620
- Testing
- Endoscopic ultrasound examination
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Orlando Health, Inc.
Pancreatic Cancer
Radiofrequency Probe for Management of Unresectable Bile Duct and Pancreatic Cancer
The purpose of this study is to determine whether the use of an FDA approved endoscopic bipolar catheter (EndoHPB) will ablate tissue in malignant tumors within the pancreatic ducts.
- Trial name
- EndoHPB (NCT02042859)
- Testing
- Endoscopic Bipolar RadioFrequency Probe used to remove tumors in bile duct to manage Pancreatic Cancer
- Volunteers
- 40 people
- Sponsor
- Ochsner Health System
Polyps
Experience and Enhancement: Improving Colonoscopic Polyp Detection
The study looks at 2 hypotheses in 2 patient groups: 1. Are more experienced endoscopists better at detecting subtle lesions (polyps) on the lining of the colon (large bowel) than less experienced endoscopists? 2.
- Trial name
- NCT00237276
- Testing
- colonoscopy
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Artificial Intelligence Assistance in Endoscopy Recovery, AI Validation
AI Assistance in GI Endoscopy Recovery Assessment
We have developed and validated an AI model to assess endoscopy recovery status based on 400 voice recordings from 200 patients. This model has a mean accuracy of 84.14% with a mean area under the curve (AUC) of 0.91.
- Trial name
- AIVR2 (NCT06923059)
- Testing
- AI-assisted endoscopy recovery assessment
- Where
- Hong Kong
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Liver Cirrhosis, Esophageal and Gastric Varices
The Effects of Early Enteral Nutrition on Endoscopic Therapy of Esophagogastric Varices in Liver Cirrhosis
The purpose of this study was to evaluate the safety of early enteral nutrition on endoscopic therapy of esophagogastric varices in Liver Cirrhosis ,and to assess the impact of different eating times on patients, so as to…
- Trial name
- NCT04823780
- Testing
- nutrient solution
- Where
- China
- Volunteers
- 397 people
- Sponsor
- Qilu Hospital of Shandong University
GERD
Endoscopic Esophageal Topography (Endoflip 2.0) Versus High-resolution Manometry (HRM)
The purpose of the study is to investigate the use of FLIP topography in patients undergoing evaluation for gastroesophageal reflux disease (GERD).
- Trial name
- NCT05089929
- Testing
- Endoflip 2.0, High Resolution Manometry
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Ohio State University
Biopsy, Fine-needle, Pancreatic Neoplasm
EUS-FNB for Solid Pancreatic Lesions: Side-fenestrated Vs Fork-tip Needle
Rationale: Until now there are no prospective studies comparing the 22 gauge and 25 gauge side-fenestrated and fork-tip needles.
- Trial name
- NCT03622229
- Testing
- Histologic evaluation
- Where
- 2 sites in Italy
- Volunteers
- 192 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Gastrointestinal Bleeding
Efficacy of a Novel Hemostatic Powder in GI Bleeding
Hemospray™ is a new endoscopic hemostatic powder. Aims of this multicenter prospective study is to determine effectiveness of Hemospray™ on short and medium term in different clinical situations, predictive factors of rebleeding…
- Trial name
- GRAPHE (NCT02595853)
- Testing
- Non interventional study
- Where
- 19 sites in France, Monaco
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
Anesthesia, Sedation
EEG-Guided Sedation in ERCP Procedures
Patients undergoing ERCP have a wide range from patients with poor general condition and septicaemia findings to outpatients who come as day patients without any other additional disease.
- Conditions
- Anesthesia, Sedation, Sedation Complication, Anesthesia, Intravenous
- Trial name
- ERCP-EEG (NCT06866886)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Gastrointestinal Hemorrhage
Endoscopic Evaluation of Lower Gastrointestinal Bleeding (GIB) in Patients Presenting With Melena
To evaluate the incidence and etiology of small bowel or large bowel bleeding in patients presenting with melena.
- Trial name
- NCT00164723
- Testing
- Capsule endoscopy
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Chinese University of Hong Kong
Achalasia, Gastroesophageal Reflux Disease
Prospective Collection of Outcome Data Post POEM-TIF Procedure
Per Oral Endoscopic Myotomy has been established as a safe and effective treatment of Achalasia type I and II; however, it is limited by post-procedure gastroesophageal reflux.
- Trial name
- NCT04052581
- Testing
- POEM-TIF
- Sponsor
- Johns Hopkins University
Barrett Esophagus, Barretts Esophagus With Dysplasia
Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples
This clinical trial evaluates the use of cytosponge, a minimally invasive collection device, for the detection of Barrett's esophagus (BE) in patients undergoing endoscopy.
- Conditions
- Barrett Esophagus, Barretts Esophagus With Dysplasia, Barrett's Esophagus Without Dysplasia, Esophageal Adenocarcinoma
- Trial name
- SOS4C (NCT06071845)
- Testing
- Cytosponge Procedure, Endoscopic Assessment
- Where
- 5 sites in United States
- Volunteers
- 450 people
- Sponsor
- Mayo Clinic
Failure to Thrive, Endoscope
Role of Gastroinestinal Endoscopy in Pediatric Failure to Thrive
This study aims to evaluate the diagnostic role of gastrointestinal endoscopy in children presenting with failure to thrive and its correlation with histopathology and other diagnostic modalities.
- Trial name
- NCT07160387
- Volunteers
- 50 people
- Sponsor
- Assiut University
Colonic Diseases
Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) Preparation and Procedure
The purpose of this study is to evaluate the effect of a modified Prep and procedure on colon cleansing level and capsule excretion rate.
- Trial name
- NCT00885209
- Where
- 5 sites in Spain
- Volunteers
- 127 people
- Sponsor
- Medtronic - MITG
Muskuloskeletan Pain
Ergonomic Evaluation of Exoskeleton Use in Transoral, Endoscopic, and Transcervical ENT Surgery: A Single Site Non-blinded Study
The goal of this observational study is to learn whether the use of an exoskeleton system can reduce musculoskeletal strain and fatigue during ENT surgical procedures in ENT surgeons performing transoral, endoscopic, and…
- Trial name
- ExoskeletonENT (NCT07855159)
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- East and North Hertfordshire NHS Trust