Clinical trials: Endoscopic Assessment
Malnutrition
Prospective Evaluation of NOTES (Natural Orifice Translumenal Endoscopic Surgery) PEG "Rescue"
The purpose of this study is to determine: 1. Utility of urgent upper endoscopy in setting of dislodges (percutaneous endoscopic gastrostomy) PEG tube. 2.
- Trial name
- PEGRescue (NCT01119040)
- Testing
- Natural Orifice Translumenal Endoscopic Surgery
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Gastrointestinal Motility
Evaluation of Gastrointestinal Motility With SmartPill
The purpose of this study is to evaluate the clinical usefulness of a capsule (SmartPill~) measuring pH, pressure and temperature from within the entire GI tract to determine gastric emptying time, combined small and large bowel…
- Trial name
- NCT01159002
- Testing
- SmartPill
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Louisville
Silent Aspiration, Post-Extubation Dysphagia
Silent Aspiration Following Extubation in the ICU
Post-extubation dysphagia is common in critically ill patients and may lead to silent aspiration, which often remains undetected because patients do not exhibit overt clinical signs such as coughing or choking.
- Conditions
- Silent Aspiration, Post-Extubation Dysphagia, Deglutition Disorders, Critical Illness
- Trial name
- SAFE-ICU (NCT07635888)
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing (FEES)
- Where
- United Arab Emirates
- Volunteers
- 274 people
- Sponsor
- Cleveland Clinic Abu Dhabi
Gastrointestinal Hemorrhage, Hematemesis; With Ulcer
Efficacy and Safety of Nexpowder™ for Non-variceal, Upper Gastrointestinal Bleeding
The purpose of this pilot clinical trial is to confirm the efficacy and safety of Nexpowder™ for hemostasis in pilot cohort of patients with NVUGIB in Singapore
- Conditions
- Gastrointestinal Hemorrhage, Hematemesis; With Ulcer, Endoscopy
- Trial name
- NCT06269588
- Testing
- Nexpowder
- Where
- Singapore
- Volunteers
- 24 people
- Sponsor
- Changi General Hospital
Other Surgical Procedures
Evaluation of Abdominal Wall Lifting During Laparoscopic Direct Trocar Insertion
In laparoscopy, over %50 of the all complications occur during establishment of the pneumoperitoneum. Lifting of the anterior abdominal wall is aimed to increase the distance between the abdominal wall and the intrabdominal…
- Trial name
- NCT01726231
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bagcilar Training and Research Hospital
Achalasia
Evaluation of a Novel Endoscopic Treatment for Achalasia
This study is to evaluate outcomes of a less invasive surgical procedure for the treatment of achalasia.
- Trial name
- POEM (NCT01770249)
- Testing
- Per-oral Endoscopic Esophagomyotomy (POEM)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Rhinosinusitis Chronic, Bleeding
This Study Aims to Assess the Impact of 50°C Saline Irrigation on the Overall Intraoperative Blood Loss and Surgical Visualization During Endoscopic Sinus Surgery for Rhinosinusitis.
Objectives: Intraoperative bleeding during endoscopic sinus surgery for severe rhinosinusitis may significantly compromise the surgical field.
- Trial name
- NCT07627789
- Testing
- Hot saline irrigation, Room-temperature saline irrigation
- Where
- Poland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Military Institute of Aviation Medicine
Gastrointestinal Neoplasia, Hirschsprung's Disease
Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy
To test the idea that submucosal endoscopy is effective and safe for endoscopic myotomy, endoscopic submucosal dissection, and access for tissue acquisition and resection.
- Conditions
- Gastrointestinal Neoplasia, Hirschsprung's Disease, Esophageal Obstruction, Gastroparesis
- Trial name
- NCT03626350
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Hiatal Hernia With Gastroesophageal Reflux Disease
Comparison of Laparoscopic Nissen Fundoplication and Hill-Snow Repair for Hiatus Hernia With Endoscopic Evaluation
The goal of this clinical trial is to compare the clinical efficacy and safety of laparoscopic Nissen fundoplication (LNF) versus laparoscopic Hill-Snow repair (LHS) in the management of patients with congenital hiatus hernia, to…
- Trial name
- NCT07387042
- Testing
- Laparoscopic Hill-Snow repair, Laparoscopic Nissen Fundoplication
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Sleep Apnea
Evaluation of Obstructive Sleep Apnea With Long Range 3D Endoscopic Fourier Domain Optical Coherence Tomography (FDOCT)
The purpose of this study is to determine whether the Optical coherence tomography (OCT) can image the structure and geometry of hollow organs of the upper airway in sleep disorder.
- Trial name
- NCT01485497
- Testing
- 3D endoscopic Fourier Domain OCT
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Obstructive Jaundice, Biliary Stricture
Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis
The use of an endoprothesis in a pancreatic duct is a measure to minimize the incidence and severity of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis.
- Conditions
- Obstructive Jaundice, Biliary Stricture, Sphincter of Oddi Dysfunction
- Trial name
- ARCHIMEDE (NCT03977779)
- Testing
- Placement of ARCHIMEDES fast biodegradable stent during the Endoscopic Retrograde CholoangioPancreatography
- Where
- 2 sites in France
- Volunteers
- 46 people
- Sponsor
- Institut Paoli-Calmettes
Gastric Cancer, Gastric Neoplasms
Confocal Endoscopic Microscopy for Detection of Early Stage Gastric Cancer in Subjects With Hereditary Diffuse Gastric Cancer Syndrome
Background: People with hereditary gastric cancer syndrome are at increased risk of getting cancer in their stomach. These people should have regular endoscopies and biopsies to check for cancer if they are choosing to keep their…
- Trial name
- NCT03648879
- Testing
- Endoscope+Cellvizio(R) 100 microscope
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Cancer Institute (NCI)
Bowel Cancer, Bowel Diseases, Inflammatory
LuCID - Investigating the Use of a Novel Digital Rectoscope for Community Examinations During COVID-19
The LumenEye scope and CHiP platform will be piloted in a number of clinical settings including remote colorectal clinics. The rationale is to perform an initial pilot study to determine the clinical utility of the LumenEye…
- Conditions
- Bowel Cancer, Bowel Diseases, Inflammatory, Rectal Bleeding
- Trial name
- LuCID (NCT05043363)
- Testing
- LumenEye X1 digital rectoscope
- Where
- United Kingdom
- Volunteers
- 114 people
- Sponsor
- Imperial College London
Gastric Cancer, Precancerous Lesion
Nasal Endoscopic Screening and Risk Assessment for Early Gastric Cancer
Pepsinogens (PGs) can be used for gastric cancer (GC) screening, but the cutoff levels vary among studies, and PG levels are influenced by numerous factors.
- Conditions
- Gastric Cancer, Precancerous Lesion, Helicobacter Pylori Infection
- Trial name
- NCT04989153
- Testing
- pepsinogen
- Where
- 9 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Adenoma Detection Rate Improvement in Screening Colonoscopy
Endoscopic Size Assessment of Advanced Adenomatous Polyps
The investigators are retrospectively comparing detection rates of adenomatous polyps, advanced adenomas, and size assessment of the polyps among Rush University Medical Center endoscopists.
- Trial name
- NCT02193646
- Where
- United States
- Volunteers
- 1,930 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Pancreatic Neoplasms, Pancreatitis
Contrast EUS of the Pancreas
RATIONALE: Endoscopic Ultrasound (EUS) is the leading method to evaluate the pancreas but there may be difficulty characterizing small lesions, tumors which are not adenocarcinomas and neoplasia in the setting of pancreatitis.
- Conditions
- Pancreatic Neoplasms, Pancreatitis, Pancreatic Cyst
- Trial name
- NCT02863770
- Testing
- EUS enhanced with contrast to evaluate pancreas
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Southern California
Post-extubation Dysphagia
Post-extubation Dysphagia
Mechanical ventilation is a widely used treatment on the Intensive Care Unit (ICU). Swallowing dysfunction (dysphagia) after extubation may cause aspiration, and is associated with poor outcomes: pneumonia, reintubation, a…
- Trial name
- NCT03761823
- Where
- Netherlands
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pancreatic Neoplasms
Comparation Between Needles for EUS-guided Sampling of Solid Pancreatic Lesions
This is a randomized study in order to compare the diagnostic yield (primary outcome) of EUS-guided sampling of pancreatic solid lesions obtained with the 25-gauge Franseen and the 25-gauge standard needle in patients undergoing…
- Trial name
- NCT04877340
- Testing
- needle punction
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Ampulla of Vater Intestinal-Type Adenoma
The Use of Cap-assisted Forward Viewing Endoscopy for Examination of the Ampulla of Vater
The aim of this study is to compare the visualization rates of the ampulla of Vater using forward- viewing endoscopes with or without cap attached to the distal end in the same patient.
- Trial name
- NCT02867826
- Testing
- Cap
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Barretos Cancer Hospital
Deglutition Disorders, Swallowing Disorder
Validation of BRACS to European Portuguese
The goal of this observational study is to translate and validate the fiberoptic endoscopic evaluation of swallowing scale "The Boston Residue and Clearance Scale - BRACS" to European Portuguese
- Conditions
- Deglutition Disorders, Swallowing Disorder, Dysphagia, Oropharyngeal
- Trial name
- NCT06558435
- Testing
- FEES
- Where
- Portugal
- Volunteers
- 16 people
- Sponsor
- Centro Hospitalar de Entre o Douro e Vouga