Clinical trials: Endoscopic Assessment
Colonoscopy
PillCam Colon 2 Capsule Endoscopy (PCCE) After Incomplete Colonoscopy
Purpose of study: To evaluate the efficacy of PillCam Colon2 in subjects with an incomplete standard colonoscopy Study design: 4 centers, prospective, cohort study Number of subjects: 74 subjects Subject population: Patients that…
- Trial name
- PCCE (NCT01480635)
- Where
- 6 sites in Germany
- Volunteers
- 74 people
- Sponsor
- Bethesda Krankenhaus
Post-ERCP Acute Pancreatitis
Evaluation of Post-ERCP Pain as a Predictor for Post-ERCP Pancreatitis
Pancreatitis is the most common complication after ERCP, although its frequency varies significantly depending on the study from < 2% up to 40%.
- Trial name
- PEP-PREPARE (NCT04770857)
- Testing
- Visual analogue scale
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- Nicola Frei
Schistosomiasis Mansoni, Portal Hypertension
Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery
Upper gastrointestinal bleeding (UGIB) is a major cause of morbidity and mortality in patients with portal hypertension secondary to schistosomiasis mansoni.
- Conditions
- Schistosomiasis Mansoni, Portal Hypertension, Upper Gastrointestinal Bleeding
- Trial name
- NCT01931826
- Testing
- Endoscopic treatment, Total EGDS+ endoscopy
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Universidade Estadual de Ciências da Saúde de Alagoas
Pancreatic Space Occupying
Research on the Value of Genomics Research Based on Ultrasound Endoscopic Biopsy in the Differential Diagnosis and Prognostic Evaluation of Pancreatic Occupancy
To clarify the value of genomic testing in the clinical diagnosis or prognosis of pancreatic space occupation, provide a basis for the selection of clinical diagnosis methods for pancreatic space occupation, optimize clinical…
- Trial name
- NCT04986215
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Gastroesophageal Reflux Disease, Dyspepsia
Evaluation of Efficiency of Esophageal Capsule Endoscopy in the Screening of Patients With Gastroesophageal Reflux Disease or Dyspepsia as Compared to Upper Endoscopy
The exploration of evocative symptoms of esophageal reflux disease or dyspepsia is based on a relatively invasive endoscopic examination, often badly tolerated, and which, in France, is carried out in 50% of the cases under…
- Trial name
- NCT00217347
- Testing
- Esophageal Capsule Endoscopy
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Crohn's Disease, Inflammatory Bowel Diseases
Evaluation of the Response of Itraconazole and Terbinafine Therapy in Subjects With Crohn's Disease
This study will evaluate the response of itraconazole and terbinafine therapy compared to placebo in patients with mild to moderate Crohn's disease (CD).
- Trial name
- CD-IT (NCT05049525)
- Testing
- Itraconazole 400 mg/day and terbinafine 500 mg/day administered orally.
- Where
- 4 sites in Canada
- Volunteers
- 16 people
- Sponsor
- Montreal Heart Institute
Gastrointestinal Disease
Sedation Using Intranasal Dexmedetomidine in Upper Gastrointestinal Endoscopy
Upper gastrointestinal endoscopy, like many other diagnostic and therapeutic procedures, may be associated with discomfort. Although upper endoscopy is usually of shorter duration and better tolerated by patients, most trials…
- Trial name
- NCT01887184
- Testing
- Dexmedetomidine
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Pelvic Organ Prolapse
VNOTES Approach in Mesh Free Sacrocolpopexy: A Functional and Anatomic Evaluation
This study aims to evaluate the effectiveness of mesh-free sacrocolpopexy performed using the VNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery) technique in the surgical treatment of pelvic organ prolapse.
- Trial name
- vnotes (NCT07114029)
- Testing
- Mesh-free Sacrocolpopexy via VNOTES
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Early Gastric Cancer
Necessity Assessment of ME-NBI Targeted Biopsy Compared With EFB
The aim of the present study was to assess whether it was necessary to conduct magnifying endoscopy with narrow band imaging (ME-NBI) targeted biopsy compared with endoscopic forceps biopsy (EFB) from white light endoscopy in…
- Trial name
- NCT02738294
- Testing
- ME-NBI observation and ME-NBI targeted biopsy
- Where
- China
- Volunteers
- 211 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Lower Gastrointestinal Bleeding, Small Bowel Bleeding
Urgent Panendoscopy in Patients Presenting With Hematochezia
Gastrointestinal bleeding is a significant emergency condition requiring prompt diagnosis. Current evidence presents a clinical paradox: urgent colonoscopy (within 24 hours) shows no clear benefit in several studies, while urgent…
- Trial name
- NCT06985277
- Testing
- Urgent endoscopy strategy, Standard colonoscopy with standard VCE group
- Where
- Thailand
- Volunteers
- 188 people
- Sponsor
- Mahidol University
Crohn's Disease
Evaluation of Capsule Endoscopy in Patients With Suspected Crohn's Disease
The aim of this study is to validate the ability of Capsule Endoscopy (CE) to accurately diagnose small bowel (SB) Crohns disease in patients with symptoms of abdominal pain and diarrhea.
- Trial name
- MA-51 (NCT00487396)
- Testing
- Capsule Endoscopy
- Where
- 11 sites in United States, Canada and 2 more
- Volunteers
- 98 people
- Sponsor
- Medtronic - MITG
Barrett Esophagus
Evaluation of Performance Characteristics of Capsule Endoscopy With PillCam UGI Capsule Compared to Standard Endoscopy
This study is to examine the benefits of newly designed capsule with enhanced frame rate and wide angle compared to standard endoscopy, which may help enhance detecting esophageal diseases that otherwise may have been out of…
- Trial name
- NCT03167970
- Testing
- Pill cam, EGD
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Midwest Biomedical Research
Large Polyps in the Gastrointestinal Tract
Evaluation of Blood as a Submucosal Cushion During Endoscopic Polypectomy and Mucosal Resection
For removal of large flat lesions of the gastro-intestinal tract injection of a solution under the lesion creates a "safety" cushion and protects from damage to the gastrointestinal tract wall.
- Trial name
- NCT00583466
- Testing
- Autologous blood injection, Normal saline, HPMC
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Adenoma of the Accessory Papilla, Ampulloma of the Accessory Papilla
Evaluation of Oesogastroduodenoscopy With Vision to 245 ° (Full Spectrum Endoscopy) to View the Main Disc and Accessory
The monitoring and prognosis of patients with familial polyposis adenomatous rests on analysis of the transitional mucosa at the anal margin and especially on the tracking, characterization and resection of lesions of dysplasia…
- Trial name
- FUSE-TM-Duo (NCT02859883)
- Testing
- gastroscope FUSE™
- Where
- France
- Volunteers
- 73 people
- Sponsor
- Institut Paoli-Calmettes
Esophageal Lesions
Endoscopic I-scan Versus Histopathological Evaluation Of Esophageal Lesions
Considering esophageal diseases, according to a cross-sectional study of endoscopic findings in patients who underwent upper endoscopy at the Fayoum University Hospital, the most common esophageal conditions seen with the…
- Trial name
- NCT05876702
- Testing
- endoscopy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
GERD
Endomina Suturing Device as a Treatment of GERD.
Gastroesophageal Reflux Disease (GERD) is a common problem affecting 10-20% of the population in the Western World. Surgical therapy is able to restore the EGJ barrier function against reflux of the gastric content, decreases…
- Trial name
- NCT03999502
- Testing
- Endomina
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Erasme University Hospital
Gastro -Oesophagal Reflux, Laryngo-pharyngeal Reflux
European TIF2.0 Registry
This is a European, multi-centre, prospective registry that aims to determine the safety and efficacy of transoral incisionless fundoplication, with or without concomitant hiatal hernia repair, for the treatment of patients with…
- Trial name
- EURO-TIF (NCT07395219)
- Testing
- Transoral incisionless fundoplication with or without concomitant hiatal hernia repair with the EsophyX device
- Where
- 7 sites in Austria, Italy and 5 more
- Volunteers
- 500 people
- Sponsor
- Cleveland Clinic London
Colorectal Cancer, Polyp, Colonic
Technical Feasibility Evaluation of Mucosal Staining During Colon Capsule Endoscopy (CCE) Procedure in Colorectal Cancer (CRC) High Risk Population, When Using MB-MMX
A prospective, single-center, single-arm, non-randomized, post-market pilot study evaluating the technical feasibility of mucosal staining during COLON2 Capsule Endoscopy (CCE) procedure in population at high risk for Colorectal…
- Trial name
- NCT05022719
- Testing
- PillCam Colon2 procedure with MB-MMX
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Medtronic - MITG
Esophageal Food Impaction
CLEANS Technique for the Treatment of Esophageal Food Impaction
This clinical investigation is to evaluate the safety, performance, and efficacy of a novel endoscopic technique for resolving esophageal food impactions by using a novel hollow suction catheter, Piranha GI Aspiration Catheter…
- Trial name
- NCT03570567
- Testing
- Piranha Treatment
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Biomerics, LLC
Chronic Kidney Diseases, Iron-Deficiency Anemia
Endoscopy in CKD With Iron Deficiency Anemia
Iron deficiency anemia is very common in CKD patients. Data about gastrointestinal lesions in Arab patients are insufficient.
- Trial name
- NCT05240677
- Testing
- Upper GIT endoscopy
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Walid Ahmed Ragab Abdelhamid