Clinical trials: Endoscopic Assessment
Rhinosinusitis Chronic, Sinus Cancer
TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality
The goal of this interventional study is to compare the efficacy (surgical field quality and intra-operative blood loss) or cost of TIVA alone to general inhalational anesthetics with intravenous TXA in patient participants who…
- Conditions
- Rhinosinusitis Chronic, Sinus Cancer, Sinus Polyp, Encephalocele
- Trial name
- NCT05639686
- Testing
- Tranexamic acid injection, Total Intravenous Anesthesia, Inhalational isoflurane
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital
Inflammatory Bowel Diseases
MACCS: Multicenter Australian CE in Patients With Suspected Crohn's Disease Study
This is a prospective study aimed to validate the ability of capsule endoscopy to accurately diagnose small bowel Crohn's disease in symptomatic patients who have a non-diagnostic standard workup.
- Trial name
- MACCS (NCT00434551)
- Where
- 8 sites in Australia
- Volunteers
- 119 people
- Sponsor
- Medtronic - MITG
GI Endoscopy
Evaluation of the Incidence of Myocardial Damage Following Upper and Lower Gastrointestinal Endoscopy in High-risk Patients
Hypoperfusion occurs following anaesthesia induction as a result of: 1. a reduction in venous return and cardiac output subsequent to the dilatation of the venous reservoir, and 2.
- Trial name
- NCT07179549
- Volunteers
- 120 people
- Sponsor
- European Society of Anaesthesiology
Rectal Cancer
Evaluate Efficacy, Morbidity and Functional Outcome of Endoscopic TranAnal Proctectomy vs Standard Transabdominal Laparoscopic Proctectomy for Rectal Cancer
Standard surgical treatment of mid and low rectal cancer is total mesorectal excision (TME). Originally performed by open surgery, TME demonstrated improved local control and reduced urogenital morbidity.
- Trial name
- ETAP (NCT02584985)
- Testing
- ETAP, Standard Transabdominal Laparoscopic Proctectomy
- Where
- France
- Volunteers
- 226 people
- Sponsor
- Institut Paoli-Calmettes
Dysphagia
Validation of the Gugging Swallowing Screen for the Intensive Care Unit
Aetiology of dysphagia after extubation is unknown and considered to be multifactorial. Use of a standardized dysphagia- screening permits an early diagnosis.
- Trial name
- GUSS-ICU (NCT04532398)
- Testing
- Gugging swallowing screen - ICU (GUSS-ICU) index test, Flexible Endoscopic Evaluation of Swallowing (FEES) reference test
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University Hospital, Basel, Switzerland
Dudoenoscope Assessment Tool
The Development and Evaluation of a Novel Duodenoscope Assessment Tool
Endoscopic retrograde cholangiopancreatography (ERCP) procedures are performed using duodenoscopes for the treatment of pancreatic and biliary diseases.
- Trial name
- NCT04004533
- Testing
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Where
- 9 sites in United States
- Volunteers
- 745 people
- Sponsor
- AdventHealth
Colorectal Cancer
Point of Care Faecal Immunochemical Testing for Colorectal Cancer
Blood that can be detected in stool via faecal immunochemical testing is a recognised risk factor for the presence of colorectal cancer. There are a number of point of care faecal immunochemical testing devices available.
- Trial name
- POCFIT (NCT04402424)
- Testing
- Faecal Immunochemical Testing
- Where
- United Kingdom
- Volunteers
- 631 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Bladder Cancer
Validation of Endoscopic Bimodal Imager for the Bladder Cancer Detection
This study evaluates the therapeutic value of: (i) simultaneous endoscopic visualization of the inner bladder using white light and blue light excitations and (ii) high resolution panoramic images of the bladder inner wall.
- Trial name
- CyPaM2 (NCT02800473)
- Testing
- Strorz (commercial), CyPaM2 (experimental)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Institut de Cancérologie de Lorraine
Identify Characteristics of Colonoscopists During Endoscopy
Evaluation of Handheld Colonoscopy Force Monitor by Expert Endoscopists in the Performance of Colonoscopy
The purpose of this study is to evaluate a handheld Colonoscopy Force Monitor(CFM™), a push-pull force and torque measuring device, that grips the shaft of the colonoscope and wirelessly transmits and records all the forces…
- Trial name
- NCT00797914
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Artann Laboratories
Intubation, Endoscopy
Endoscopic Evaluation of the Paediatric Airway After Prior Prolonged (>24 h) Tracheal Intubation
The purpose of this study is to determine whether possible damages of the trachea caused by a prior prolonged intubation (> 24h) can be observed by rigid endoscopy of the trachea and if cuffed tracheal tubes cause less damages…
- Trial name
- NCT02350933
- Testing
- Endoscopy
- Where
- 5 sites in Germany, Netherlands and 2 more
- Volunteers
- 1,000 people
- Sponsor
- University Children's Hospital, Zurich
Liver Cirrhosis
EUS Share-wave in Patients With Liver Cirrhosis
Patients with chronic liver disease may develop progressive hepatic fibrosis. Liver cirrhosis should be detected at the early stages in order to avoid the complications related to these two conditions.
- Trial name
- NCT04644055
- Testing
- EUS- share wave of the liver
- Where
- Ecuador
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Esophageal Varices
"Evaluation of the PillCam™ESO Capsule in the Detection of Esophageal Varices
The purpose of the study is to access the accuracy of the PillCam Eso capsule in identifying the presence of suspected esophageal disease in patients undergoing surveillance or screening for esophageal disease by standard…
- Trial name
- MA-37 (NCT00481416)
- Testing
- PillCam Eso
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 318 people
- Sponsor
- Medtronic - MITG
Colonoscopy, Incomplete Colonoscopy
Endorail in Long Lasting Colonoscopy
Patients with long lasting colonoscopy are characterized by higher risk of incompletion. Endorail is an accessory for colonoscopy aimed at facilitating progression of the endoscope in the large intestine.
- Trial name
- NCT05626738
- Testing
- ENDORAIL
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 38 people
- Sponsor
- Endostart srl
Transforaminal Lumbar Interbody Fusion Surgery
The Objective of the Protocol is to Generate Real World Evidence (RWE) Supporting the Safety, Performance, and Health Economics of Using the Regulatory Approved and Commercially Available EARP Interbody System Used During Lumbar Interbody Fusion (LIF) Procedures With the EARP Nerve Cuff Electrode
The goal of the trial is to generate data to support the safety, performance, and cost effectiveness of using the EARP devices during Lumbar Interbody Fusion (LIF) procedures.
- Trial name
- EARP-2 (NCT07020000)
- Testing
- Device: Nerve Cuff and Retractor System
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- Retropsoas Technologies, LLC
Liver Diseases, Liver Neoplasms
Endoscopic Ultrasound Guided Liver Biopsy and Portal Pressure Registry
Patient Registry aiming to provide regional evidence documenting the clinical merit of EUS (Endoscopic_ Ultrasound) guided liver biopsy, per local standard of practice, in patients with suspected liver disease indicated for an…
- Conditions
- Liver Diseases, Liver Neoplasms, Liver Dysfunction, Liver Failure, Acute
- Trial name
- REGAL (NCT05817994)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheikh Shakhbout Medical City
Laryngotracheal Stenosis
Assessment of Primary Oxygenation and Airflow Measurement for Endoscopic Laryngeal Surgery
This research is being done to determine the resistance across stenosis in the airway.
- Trial name
- NCT03222869
- Testing
- Measure Airway Resistance Across Stenosis
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Rectal Neoplasms, Neuroendocrine Tumors
Clinical Relevance of the Salvage Treatment for Colorectal Neuroendocrine Tumors
we evaluated all related clinical and pathologic data of rectal NET cases, including the resection margin status, NET grading, and lymphovascular invasion status.
- Trial name
- NCT06143605
- Testing
- salvage treatment
- Volunteers
- 527 people
- Sponsor
- Yanhong Deng
Inflammatory Bowel Disease, Crohn Disease
Deep Endoscopic Remission Assessed by a Surrogate Biomarker in Patients With Inflammatory Bowel Disease
We hypothesize that the number of needed endoscopic procedure performed at IBD patients (adult and children), can be reduced by using an individualized algorithm of symptoms, blood and faecal biomarkers.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT01861288
- Where
- Denmark
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Gastric Transit Time
Study to Evaluate the Efficacy of Oral Dissolving Metoclopramide Before Video Capsule Endoscopy
Summary: This study investigates the use of oral dissolving metoclopramide during standard video capsule endoscopy. Metoclopramide is a pro -motility agent, that is, this medication helps with movement through the stomach and…
- Trial name
- NCT01631994
- Testing
- metoclopramide
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Superficial Esophageal Cancer, Oesophageal Adenocarcinoma
Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal Dissection
In France in 2018, there were an estimated 2,074 new cases of esophageal adenocarcinoma and 3,224 cases of squamous cell carcinoma.
- Conditions
- Superficial Esophageal Cancer, Oesophageal Adenocarcinoma, Oesophageal Squamous Cell Carcinoma, Barretts Esophagus With Dysplasia
- Trial name
- FEO (NCT07343869)
- Where
- France
- Volunteers
- 750 people
- Sponsor
- Société Française d'Endoscopie Digestive