Clinical trials: Endoscopic Assessment
Colonic Polyp
Evaluation of a Double Balloon Interventional Platform (DiLumen) for Complex Colonic ESD
The purpose of this randomized study is to compare ESD procedural time and cost facilitated with a dual balloon accessory device versus ESD procedures performed without the accessory device.
- Trial name
- NCT03846609
- Testing
- double balloon interventional platform (DiLumen), no double balloon interventional platform (DiLumen)
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Mercy Medical Center
Reflux Disease, Reflux, Gastroesophageal
One-stop-shop Endoscopy in Reflux-patients: Evaluation of ENT and GI Features
Patients suffering from gastroesophageal reflux may suffer from both esophageal and laryngeal irritations. The investigators developed an endoscopic technique called functional endoscopy to evaluate alterations in the larynx and…
- Conditions
- Reflux Disease, Reflux, Gastroesophageal, Reflux, Laryngopharyngeal
- Trial name
- ENTGI-reflux (NCT05634187)
- Testing
- Functional endoscopy
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- University Hospital Muenster
Malignant Obstruction of the Common Bile Duct
Clinical Feasibility Study of Allium's Biliary Stent
The purpose of this study is to evaluate the safety and efficacy of the Allium Biliary Stent in malignant obstructions of the common bile duct.
- Trial name
- NCT00448006
- Testing
- Allium Biliary Stent
- Where
- Israel
- Sponsor
- Allium, Ltd.
Esophageal Varices, Gastric Varices
Evaluation of Gastroesophageal Varices by Transnasal Endoscopy.
The study aims to evaluate the feasibility of transnasal endoscopy in patients with portal hypertension, cirrhotic and non-cirrhotic.
- Conditions
- Esophageal Varices, Gastric Varices, Hypertension Portal, Liver Cirrhosis
- Trial name
- NCT02767206
- Volunteers
- 50 people
- Sponsor
- Federal University of Minas Gerais
Anaesthesia, Rhinitis
A Comparison Between Co-phenylcaine Nasal Spray and Nasal Nebulization Prior to Rigid Nasoendoscopic Examination
Co-phenylcaine is a widely available nasal spray commonly used by otorhinolaryngologists for the purpose of decongestion and local anesthetic prior to a nasoendoscopic or nasopharyngolaryngoscopy.
- Trial name
- NCT03380715
- Testing
- Nasal nebulisation into the right nostril, Nasal Spray into the right nostril
- Where
- 2 sites in Malaysia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Bladder Cancer
Bladder Tumor Biopsy Study to Improve Preoperative Determination of Stage and Grade
To assess whether the addition of a bladder tumor biopsy improves the level of agreement between the pretreatment endoscopic impression and the final postoperative pathology determination of stage and grade in non-muscle-invasive…
- Trial name
- NCT02992990
- Testing
- Bladder tumor biopsy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Pancreatic Cancer
Radiofrequency Probe for Management of Unresectable Bile Duct and Pancreatic Cancer
The purpose of this study is to determine whether the use of an FDA approved endoscopic bipolar catheter (EndoHPB) will ablate tissue in malignant tumors within the pancreatic ducts.
- Trial name
- EndoHPB (NCT02042859)
- Testing
- Endoscopic Bipolar RadioFrequency Probe used to remove tumors in bile duct to manage Pancreatic Cancer
- Volunteers
- 40 people
- Sponsor
- Ochsner Health System
Familial Adenomatous Polyposes, Duodenal Polyposis
Endoscopic Evaluation of Duodenal Polyposis in Patients With Familial Adenomatous Polyposis (FAP)
Familial adenomatous polyposis (FAP) is an autosomal dominant genetic disorder that predisposes to a number or malignant disorders [1,2].
- Conditions
- Familial Adenomatous Polyposes, Duodenal Polyposis, Duodenal Cancer
- Trial name
- NCT03346980
- Testing
- Esophagogastroduodenoscopy
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Colorectal Polyp
Web-Mediated Risk Assessment for Endoscopic Screening of Colorectal Polyps
Colorectal polyps are risk factors for cancer. Early detection of polyps is critical for colorectal cancer management. However, the diagnosis rate of patients with colorectal polyps is still low.
- Trial name
- NCT03750617
- Testing
- pre-endoscopic screening risk assessment
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- State Key Laboratory of Cancer Biology
Early Gastric Cancer, Gastric Adenocarcinoma
Image-Guided Platform-Assisted Sentinel Lymph Node Retrieval in Early Gastric Cancer
This prospective, single-center, randomized controlled trial aims to evaluate the clinical effectiveness of an Image-Guided Platform assisted by a deep learning model for sentinel lymph node (SLN) retrieval in patients with early…
- Trial name
- NCT07835087
- Testing
- Image-Guided Retrieval Specimen Platform, Traditional Palpation-Based Sentinel Lymph Node Retrieval
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Beijing Friendship Hospital
Crohn Disease
Evaluation of the Efficacy and Safety of Endoscopic Dilatation and Biological Therapy in Intestinal Stenosis Due to CD
All patients with Crohn\'s disease, already undergoing biological therapy for the treatment of clinically significant intestinal stenosis and/or already undergoing endoscopic balloon dilatation during the period January 2016…
- Trial name
- NCT06603298
- Where
- Italy
- Volunteers
- 182 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Esophageal Diseases
Ultrasound Capsule Endoscopy for Esophagus Examination
The aim of this pilot study is to assess the feasibility and safety of the clinical application of ultrasound capsule endoscopy in esophageal examination compared with conventional endoscopic ultrasound examination.
- Trial name
- NCT05054933
- Testing
- ultrasound capsule endoscopy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Platelet-rich Plasma, Endoscopic Mucosal Resection
Evaluation of the Efficacy of Platelet-rich Plasma (PRP) on Advanced Endoscopic Resection Techniques
To avoid complications secondary to advanced endoscopic resection techniques (Endoscopic Mucosal Resection -EMR- or Endoscopic Submucosal Disection -ESD-) the endoscopists have to avoid deep thermal damage and increase mucosal…
- Conditions
- Platelet-rich Plasma, Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection
- Trial name
- NCT02931149
- Testing
- Platelet-rich plasma
- Where
- Spain
- Volunteers
- 11 people
- Sponsor
- Germans Trias i Pujol Hospital
Colorectal Polyp
Assessment of Endoscopic Tip Control Using a Novel Score Based on the Snare Tip Soft Coagulation of Polypectomy Margin Defects
Colorectal cancer is the third most common malignancy worldwide and the second leading cause of cancer related death with approximately 880 792 deaths every year (9,2% of the global yearly 9.6 million cancer deaths).
- Trial name
- NCT05660317
- Testing
- Tip control score
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Ureteral Stricture
EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures
The main objective of this clinical investigation is to assess the safety and feasibility of the Optilume DCB for treatment of ureteric strictures.
- Trial name
- ENDURE1 (NCT07020520)
- Testing
- Optilume
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Urotronic Inc.
Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps
Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria
The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria.
- Conditions
- Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps, Blood Stream Infection, Anaerobic Infection
- Trial name
- AB-care (NCT06919068)
- Testing
- Colon capsule endoscopy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
The Malignant Lesions and Non-malignant Lesions of Pancreas, Bile Duct, Liver and Lymph Node
An Artificial Intelligence System for ROSE of EUS-FNA Sample: a Prospective, Multicenter, Diagnostic Study.
This is an observational study with a prospective, multicenter, disgnostic design. An artificial intelligence system named ROSE-AI system was developed using cytopathological slide images taken by microscope camera or smartphone…
- Trial name
- ROSE，EUS-FNA (NCT06718725)
- Testing
- ROSE-AI system
- Where
- China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Gastrointestinal Stromal Tumor of Stomach, Submucosal Tumor of Stomach
MCB vs EUS-FNA for Preoperative Pathological Evaluation of Gastric SMT
Gastrointestinal stromal tumors (GISTs) are the most common submucosal tumors (SMTs) of the stomach. The 2022 European Society of Oncology ESMO Diagnosis and Treatment Guidelines recommend that GISTs undergo biopsy with a clear…
- Trial name
- NCT06748690
- Testing
- mucosal cutting biopsy, endoscopic ultrasound-guided-fine needle aspiration
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Peptic Ulcer, Gastric Cancer
WEI NASAL JET for The Sedation of Outpatient Upper Gastrointestinal Endoscopy
Low pulse oximetry is the most common adverse events during sedation for upper gastrointestinal endoscopy. The main reason is the glossoptosis after sedation.
- Conditions
- Peptic Ulcer, Gastric Cancer, Esophagus Cancer, Oesophagitis
- Trial name
- NCT02436018
- Testing
- WEI NASAL JET, Nasopharyngeal airway without jet ventilator
- Where
- 3 sites in China
- Volunteers
- 1,800 people
- Sponsor
- RenJi Hospital
Polyps
Experience and Enhancement: Improving Colonoscopic Polyp Detection
The study looks at 2 hypotheses in 2 patient groups: 1. Are more experienced endoscopists better at detecting subtle lesions (polyps) on the lining of the colon (large bowel) than less experienced endoscopists? 2.
- Trial name
- NCT00237276
- Testing
- colonoscopy
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust