Clinical trials: Endoscopic Assessment
Crohn's Disease
Effects of Adalimumab on Mucosal Healing in Subjects With Crohn's Disease Involving the Colon
The goal of this study was to test whether adalimumab can induce mucosal healing in subjects with moderate to severe ileocolonic Crohn's Disease.
- Trial name
- NCT00348283
- Testing
- adalimumab
- Where
- 21 sites in United States, Austria and 6 more
- Volunteers
- 135 people
- Sponsor
- Abbott
Large Polyps in the Gastrointestinal Tract
Evaluation of Blood as a Submucosal Cushion During Endoscopic Polypectomy and Mucosal Resection
For removal of large flat lesions of the gastro-intestinal tract injection of a solution under the lesion creates a "safety" cushion and protects from damage to the gastrointestinal tract wall.
- Trial name
- NCT00583466
- Testing
- Autologous blood injection, Normal saline, HPMC
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Liver Disease, Advanced Fibrosis
A Study to Evaluate Liver Stiffness With Shear Wave Elastography
The purpose of the study is to assess the diagnostic accuracy of Endoscopic Ultrasound (EUS) shear wave elastography in liver fibrosis staging in both normal subjects and subjects with advanced liver fibrosis/cirrhosis
- Conditions
- Chronic Liver Disease, Advanced Fibrosis, Advanced Cirrhosis
- Trial name
- NCT05097963
- Testing
- Endoscopic Ultrasound Shear Wave Elastography
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Mayo Clinic
Colonoscopy, Incomplete Colonoscopy
Endorail in Long Lasting Colonoscopy
Patients with long lasting colonoscopy are characterized by higher risk of incompletion. Endorail is an accessory for colonoscopy aimed at facilitating progression of the endoscope in the large intestine.
- Trial name
- NCT05626738
- Testing
- ENDORAIL
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 38 people
- Sponsor
- Endostart srl
Gastroduodenal Ulceration
Evaluation of Upper GI Ulceration Induced by PL2200 Versus Aspirin in At-Risk Subjects
This trial is a Phase 2, randomized, controlled study to compare the degree of mucosal injury after the oral administration of an investigational product, PL2200, and a marketed 325 mg immediate-release aspirin product.
- Trial name
- NCT01646814
- Testing
- PL2200, Aspirin tablets
- Where
- 10 sites in United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- PLx Pharma
CRC Screening
Evaluation of Capsule Endoscopy With PillCam® COLON 2 in Visualization of the Colon
This study was design to establish the effectiveness of PillCam® Platform with the PillCam® COLON 2 capsule as demonstrated by the identification of subjects with polyps as compared to optical colonoscopy.
- Trial name
- NCT01372878
- Testing
- PillCam® COLON 2 procedure, Colonoscopy
- Where
- 17 sites in United States, Israel
- Volunteers
- 884 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colonic Polyps
High Definition Endoscopy With i-Scan for Small Colonic Polyp Evaluation: The HiScope Study
Current standard practice is to remove all colonic polyps found during colonoscopy as it has not been possible to distinguish between polyps with some malignant potential (adenomatous) and those with negligable malignant…
- Trial name
- HiSCOPE (NCT01761279)
- Testing
- High definition white light endoscopy
- Volunteers
- 84 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Spondyloarthritis, Enterocolitis
Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal Healing
Studies with intestinally asymptomatic patients with spondyloarthritis showed that approximately 1/3 had visible ulcers in the colon by scopic examinations and 2/3 had changes detectable by microscopy.
- Trial name
- INTASAH (NCT01174186)
- Testing
- Adalimumab
- Where
- 4 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Regionshospitalet Silkeborg