Clinical trials: Endoscopic Assessment
Chronic Kidney Diseases, Iron-Deficiency Anemia
Endoscopy in CKD With Iron Deficiency Anemia
Iron deficiency anemia is very common in CKD patients. Data about gastrointestinal lesions in Arab patients are insufficient.
- Trial name
- NCT05240677
- Testing
- Upper GIT endoscopy
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Walid Ahmed Ragab Abdelhamid
Esophageal Food Impaction
CLEANS Technique for the Treatment of Esophageal Food Impaction
This clinical investigation is to evaluate the safety, performance, and efficacy of a novel endoscopic technique for resolving esophageal food impactions by using a novel hollow suction catheter, Piranha GI Aspiration Catheter…
- Trial name
- NCT03570567
- Testing
- Piranha Treatment
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Biomerics, LLC
Endoscopy
Evaluation of Transnasal Endoscopy During COVID-19 Pandemic
Patients who received the indication for endoscopic diagnostics using gastroscopy in transnasal technique will be included into the study. The examination is carried out in standard technique and is not influenced by the study.
- Trial name
- NCT04734912
- Testing
- gastroscopy in transnasal techique
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Colon Malignant Tumor, Colon Benign Tumor
Apollo Overstitch, a Treat and Resect Model
The Overstitch (Apollo Endosurgery, Austin, Texas) is an FDA cleared product which attaches to a standard double channel endoscope.
- Trial name
- Overstitch (NCT01307813)
- Testing
- Overstitch Endoscopic Suturing System
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Breast Cancer
Nipple Aspiration, Ductal Lavage, and Duct Endoscopy For Diagnostic Assessment in Women Undergoing Surgery for Breast Cancer
RATIONALE: Diagnostic procedures, such as nipple aspiration, ductal lavage, and breast duct endoscopy, may help doctors detect and assess breast cancer cells early and plan more effective treatment.
- Trial name
- NCT00083018
- Testing
- cytogenetic analysis, proteomic profiling, cytology specimen collection procedure
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Intestinal Metaplasia of Gastric Mucosa, Artificial Intelligence
Automatic Evaluation of the Extent of Intestinal Metaplasia With Artificial Intelligence
Gastric intestinal metaplasia(GIM) is an important stage in the gastric cancer(GC). With technical advance of image-enhanced endoscopy (IEE), studies have demonstrated IEE has high accuracy for diagnosis of GIM.
- Conditions
- Intestinal Metaplasia of Gastric Mucosa, Artificial Intelligence, Endoscopy
- Trial name
- NCT05459610
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shandong University
Healthy
Comparator Study of LT-NS001 in Healthy Subjects With Endoscopic Evaluation
The purpose of this study is to compare naproxen plasma levels and gastroduodenal mucosal injury after administration of LT-NS001 as compared to Naprosyn in subjects age 45-70.
- Trial name
- NCT00750243
- Testing
- LT-NS001, Naprosyn®
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Logical Therapeutics
Oesophageal Disease
Endomina Diverticulum
Esophageal diverticulum is a rare disease. Majority comes form the pharyngo-esophageal junction (70 % Zenker's Diverticulum), 10% are mediothoracic and 20% epiphrenic.
- Trial name
- NCT03609073
- Testing
- Endomina
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Erasme University Hospital
Colorectal Cancer, Adenoma Colon
Real-time Computer-Aided Detection of Colonic Adenomas With NEC WISE VISION® Endoscopy
This is a prospective, multicenter, randomized study to evaluate the clinical performance of a novel CADe device, WISE VISION® Endoscopy System, in patients undergoing high-definition white light (HDWL) colonoscopy for screening…
- Conditions
- Colorectal Cancer, Adenoma Colon, Polyp of Colon
- Trial name
- COLOWISE (NCT05611151)
- Testing
- Computer Aided Detection (CADe)
- Where
- 5 sites in United States, Germany and 2 more
- Volunteers
- 830 people
- Sponsor
- NEC Corporation
Gastrointestinal Hemorrhage
A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer
This study is being carried out to see if constant 3 days infusion of Nexium is effective in preventing rebleeding after an endoscopic treatment.
- Trial name
- NCT00251979
- Testing
- Esomeprazole
- Where
- 78 sites in Austria, Denmark and 14 more
- Volunteers
- 1,312 people
- Sponsor
- AstraZeneca
Colorectal Adenoma, Sessile Serrated Lesion
Evaluation of 'WAYMED Endo CL CS' for Automated Detection and Diagnosis of Colorectal Adenoma and Non-Adenoma Lesions
The purpose of this clinical trial is to evaluate the effectiveness of the computer-aided diagnosis (CADx) software, 'WAYMED endo CL CS', which assists medical specialists by automatically analyzing colorectal endoscopic images…
- Conditions
- Colorectal Adenoma, Sessile Serrated Lesion, Hyperplastic Polyp, Carcinoma
- Trial name
- NCT07470827
- Testing
- WAYMED endo CL CS, Reference standard review
- Where
- South Korea
- Volunteers
- 1,178 people
- Sponsor
- WAYCEN Inc
Dyspepsia, Malabsorption Syndrome
Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children
There is some controversy in the medical literature regarding the effectiveness of topical lidocaine in children as an adjuvant drug to upper gastrointestinal endoscopy.
- Conditions
- Dyspepsia, Malabsorption Syndrome, Gastroesophageal Reflux Disease, Abdominal Pain
- Trial name
- NCT00521703
- Testing
- Lidocaine, Tannic acid
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Hospital Infantil Cândido Fontoura
Adenoma of the Accessory Papilla, Ampulloma of the Accessory Papilla
Evaluation of Oesogastroduodenoscopy With Vision to 245 ° (Full Spectrum Endoscopy) to View the Main Disc and Accessory
The monitoring and prognosis of patients with familial polyposis adenomatous rests on analysis of the transitional mucosa at the anal margin and especially on the tracking, characterization and resection of lesions of dysplasia…
- Trial name
- FUSE-TM-Duo (NCT02859883)
- Testing
- gastroscope FUSE™
- Where
- France
- Volunteers
- 73 people
- Sponsor
- Institut Paoli-Calmettes
Liver Cirrhoses, Portal Hypertension
EGD vs EUS in Diagnosing Portal Hypertension in Cirrhotic Patients.
Liver cirrhosis with the further development of portal hypertension implies structural and vasculature alteration in the portosplenic circulation.
- Trial name
- NCT04191369
- Testing
- Esophagogastroduodenoscopy, Endoscopic ultrasound
- Where
- Ecuador
- Volunteers
- 35 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Hepatolithiasis, Endoscopy, Digestive System
Evaluation of the Efficacy of the Two-point Method in Percutaneous Transhepatic Choledoscopy and the Influence of the Long-term Recurrence of Hepatolithiasis
The goal of this clinical trial is to evaluate the efficacy and safety of the two-point approach in patients with intrahepatic bile duct stones。The main questions it aims to answer are: ① By comparing the technical success rate…
- Trial name
- NCT06839612
- Testing
- Two-point method, Conventional PTCS
- Volunteers
- 157 people
- Sponsor
- Shengjing Hospital
Gallbladder Cancer, Obstructive Jaundice
Endoscopic Versus Percutaneous Drainage For Hilar Block in Gall Bladder Cancer
Cancer of the gallbladder (CaGB) is one of the most common causes of malignant obstructive jaundice. Jaundice is the second most common presentation and occurs in 30-60% of patients with CaGB.
- Trial name
- NCT00409864
- Testing
- Endoscopic biliary stenting, Percutaneous biliary stenting
- Where
- India
- Volunteers
- 182 people
- Sponsor
- All India Institute of Medical Sciences
Crohn Disease
AI-enabled Endoscopic Prediction of Post-operative Recurrence in Crohn's Disease
This is a multicentre prospective international observational study. This study aims to introduce a novel multidimensional approach to precision imaging, enabling the identification and stratification of high-risk patients who…
- Trial name
- PROSPER (NCT06505304)
- Testing
- Colonoscopy, Intestinal biopsies, Confocal laser endomicroscopy
- Where
- 15 sites in Belgium, Canada and 4 more
- Volunteers
- 225 people
- Sponsor
- University College Cork
Gastric Mucosal Lesion
Efficacy and Safety of OsrhCT and Dimethicone Emulsion Before Upper Endoscopy on Visualization of the Gastric Mucosa.
Study was designed to evaluate efficacy of OsrhCT and Dimethicone emulsion before upper endoscopy on visibility of gastric mucosa. A total of 336 subjects (both male and female) are expected to be enrolled in this trial.
- Trial name
- NCT06722664
- Testing
- Recombinant Human Chymotrypsin(OsrhCT) 4000U, Dimethicone emulsion 4ml
- Where
- 5 sites in China
- Volunteers
- 336 people
- Sponsor
- Healthgen Biotechnology Corp.
Low-output External Gastrointestinal Fistula
Glue Sealing for Patients With Low-Output ECFs
Adjuvant use of fibrin glue (FG) in the fistula tract has been shown to promote closure of low-output ECFs. The primary objectives of this study are to compare the clinical efficacy, safety of autologous platelet-rich fibrin glue…
- Trial name
- Glue-sealing (NCT01672593)
- Testing
- Endoscopy exploration and glue application, Anti-Bacterial Agents, Nutrition support
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jinling Hospital, China
Analgesics
A Safety Trial to Compare Different Analgesics in Combination With Low Dose Aspirin to Study Their Bleeding Properties and Their Effects on the Stomach
The purpose of this study is to compare several analgesics given in approved daily doses in combination with a daily cardioprotective dose of aspirin (81 mg), to study their bleeding properties and their effects on the stomach in…
- Trial name
- NCT00261586
- Testing
- aspirin, acetaminophen, ibuprofen, naproxen, celecoxib, rofecoxib
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide