Clinical trials: Endoscopic Assessment
CSF Leak
Evaluation of Internal Nasal Splint-Supported Free Graft Versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks
The study aims to compare the feasibility and effectiveness of using an internal nasal splint- supported free graft versus a nasoseptal flap alone for endoscopic repair of bilateral CSF leaks.
- Trial name
- CSF (NCT07368348)
- Testing
- Internal Nasal Splint-Supported Free Graft, Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Kafrelsheikh University
Gastro-oesophageal Adenocarcinoma
Evaluation of the Reliability of the Determination of MisMatch Repair Deficiency Status by Endoscopic Biopsies in Oesophagus and Gastric Adenocarcinoma.
Gastro-esophageal adenocarcinoma is one of the most common cancer in the world and the fourth most common cancer in France with more than 6,000 cases per year.
- Trial name
- BIOPSYGAST MMR (NCT04774367)
- Testing
- Order of forceps : First standard biopsy forceps and second large capacity biopsy forceps, Order of forceps : First large capacity biopsy forceps and second standard biopsy forceps
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreatic Cancer
Evaluation of Multiple Needle Use in EUS-FNA for Pancreatic Cancer
The aim of this study is to evaluate if the early change of needle during EUS-FNA for suspected pancreatic cancer allows an earlier preliminary cytological diagnosis of neoplasia.
- Trial name
- EMUNE-07 (NCT00548626)
- Testing
- Single needle, Multiple needle
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Chicago
Intestinal Metaplasia
Confocal Laser Endomicroscopy for the Detection of Gastric Intestinal Metaplasia: a Randomized Controlled Trial
The purpose of this study is to assess whether confocal laser endomicroscopy can reduce the biopsy number needed per patient for the detection of gastric intestinal metaplasia without the loss of corresponding diagnostic yield.
- Trial name
- NCT01024621
- Testing
- Endomicroscope, Standard endoscopy
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Shandong University
Diabetes Mellitus, Type 2
A Trial to Evaluate Safety, Feasibility and Efficacy of Endoscopic Duodenal PEF Therapy
The objective of this study is to evaluate the safety, feasibility and efficacy of pulsed electric field induced duodenal mucosal regeneration (with the Endogenex System en Gen 2 Device) combined with a GLP-1 receptor agonist…
- Trial name
- EMINENT-2 (NCT05984238)
- Testing
- PEF therapy using the Endogenex Device, Semaglutide, 1.0 mg/mL
- Where
- Netherlands
- Volunteers
- 33 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Type 2 Diabetes Mellitus (T2D), Obesity (BMI>30)
Impact of Endoscopic Sleeve Gastroplasty (ESG) in Obese Adults With Type 2 Diabetes (T2D)
The goal of this clinical trial is to determine whether Endoscopic Sleeve Gastroplasty (ESG)-induced weight loss can improve glycemic outcomes and alter the trajectory toward insulin dependence in adults with obesity and…
- Trial name
- MEASURE (NCT07639684)
- Testing
- ESG with OverStitch
- Volunteers
- 50 people
- Sponsor
- Boston Scientific Corporation
Magnetically Controlled Capsule Endoscopy, Bowel Preparation
Different Bowel Preparations in Magnetically Controlled Capsule Endoscopy
The study aimed to compare the effects of bowel preparation methods of a normal diet for 1 day, a low residue diet for 1 day, and laxative bowel cleaning on the image quality of magnetically controlled capsule endoscopy, and to…
- Trial name
- NCT06313242
- Testing
- Polyethylene Glycol Electrolytes Powder (II), Low residue diet, Normal diet
- Where
- China
- Volunteers
- 375 people
- Sponsor
- Qilu Hospital of Shandong University
Bladder Tumor
Endoscopic Resection of Bladder Tumors
To confirm the benefit of endoscopic resection under fluorescence and blue light of high grade non-muscle invasive bladder tumor, and verifying if the second endoscopic resection recommended nowadays can be deleted.
- Trial name
- NCT01750970
- Testing
- Endoscopic resection under blue light (Hexvix®)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Hopital Foch
Gastric Focal Lesion
Comparative Study of the Magnetically Guided Capsule Endoscopy Versus High Definition Gastroscopy
A capsule steered by magnetic field force developed by Siemens and Olympus has recently been evaluated in a pilot series in man with encouraging results (Rey JF, Ogata H, Hosoe N, Ohtsuka K, Ogata N, Ikeda K, Aihara H, Pangtay I…
- Trial name
- NCT01555840
- Testing
- Magnetically Guided Capsule (MGCE)
- Where
- France
- Volunteers
- 189 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pancreatic Cancer, Pain
Evaluation of Injection Techniques in Celiac Plexus Neurolysis
1. To evaluate the efficacy of EUS-CPN in subjects who experience a sympathetic response during injection when compared with subjects who do not experience sympathetic response during injection.
- Trial name
- NCT02068677
- Testing
- Sympathetic response, no sympathetic response
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- AdventHealth
Post-ERCP Acute Pancreatitis
Evaluation of Post-ERCP Pain as a Predictor for Post-ERCP Pancreatitis
Pancreatitis is the most common complication after ERCP, although its frequency varies significantly depending on the study from < 2% up to 40%.
- Trial name
- PEP-PREPARE (NCT04770857)
- Testing
- Visual analogue scale
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- Nicola Frei
Other Surgical Procedures
Evaluation of Abdominal Wall Lifting During Laparoscopic Direct Trocar Insertion
In laparoscopy, over %50 of the all complications occur during establishment of the pneumoperitoneum. Lifting of the anterior abdominal wall is aimed to increase the distance between the abdominal wall and the intrabdominal…
- Trial name
- NCT01726231
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bagcilar Training and Research Hospital
Abdomen, Mediastinum
Endoscopic Ultrasound (EUS) Artificial Intelligence Model for Normal Mediastinal and Abdominal Strictures Assessment
Therefore, a high number of procedures is necessary to achieve EUS competency, but interobserver agreement still varies widely. Artificial intelligence (AI) aided recognition of anatomical structures may improve the training…
- Conditions
- Abdomen, Mediastinum, Anatomic Abnormality, Strictures
- Trial name
- NCT05151939
- Testing
- Identification or discharge visualization of mediastinal and abdominal organ/anatomic strictures through Endoscopic ultrasound (EUS) videos by an expert endoscopist, Recognition of mediastinal and abdominal organ/anatomic strictures through Endoscopic ultrasound (EUS) videos using artificial intelligence (AI)
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Acute Variceal Bleed
A Randomized Controlled Trial to Assess the Role of Emergent vs Early Endoscopy in Child B and C Cirrhotic Patients With Acute Variceal Bleed (AVB)-EARLY - AVB
Summary-Variceal bleeding - 70% of all upper gastro-intestinal bleeding episodes in patients with portal hypertension, and they result from esophageal varices (EVs), gastric varices (GVs), or ectopic varices.
- Trial name
- NCT06785701
- Testing
- Upper Gastrointestinal Endoscopy
- Where
- India
- Volunteers
- 220 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Anastomotic Leak Rectum, Anastomotic Leak Large Intestine
Endoscopic COlorectal Mucosal Evaluation of Oxygen Tension
Anastomosis refers to the surgical connection between two segments of the bowel, typically performed during colon and rectal surgeries to restore the continuity of the digestive tract after a section has been removed.
- Trial name
- e-COMET (NCT07467980)
- Testing
- A novel endoscopic imaging system that displays real-time oxygen saturation levels
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Vanderbilt University Medical Center
Pancreatitis
Endoscopic Sphincterotomy vs. Balloon Dilation for Assessment of Pancreatitis
One of the major elements of successful endoscopic retrograde cholangiopancreatography ( ERCP) is the timely and uncomplicated cannulation of the common bile duct (CBD) .
- Trial name
- NCT02346448
- Testing
- endoscopic sphincterotomy, balloon dilatation for 3 minutes, balloon dilatation for 6 minutes
- Where
- 3 sites in Germany
- Volunteers
- 600 people
- Sponsor
- Helios Albert-Schweitzer-Klinik Northeim
Esophageal Varices, Gastric Varices
Evaluation of Gastroesophageal Varices by Transnasal Endoscopy.
The study aims to evaluate the feasibility of transnasal endoscopy in patients with portal hypertension, cirrhotic and non-cirrhotic.
- Conditions
- Esophageal Varices, Gastric Varices, Hypertension Portal, Liver Cirrhosis
- Trial name
- NCT02767206
- Volunteers
- 50 people
- Sponsor
- Federal University of Minas Gerais
Sinusitis, Maxillary Sinusitis
Study Designed to Clinically Evaluate Sinus Wash Device Prototypes
The purpose of this study is to clinically evaluate sinus wash device prototypes in patients with sinusitis during Endoscopic Sinus Surgery (ESS) and in the hospital outpatient
- Trial name
- NCT02931604
- Testing
- SinuSafe Medical Device for Maxillary Sinus
- Volunteers
- 50 people
- Sponsor
- SinuSafe Medical LTD
Sleep Apnea, Obstructive
Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea
Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients.
- Trial name
- NCT00695214
- Testing
- Propofol sedation
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of California, Los Angeles
Infection Control
Risk Assessment of Indirect Exposure to the Environment in the Gastrointestinal Endoscopy Center
Study objective: To clarify the risk of exposure to indirect contact and transmission of environmental objects during digestive endoscopy diagnosis and treatment for patients and medical staff, simulating by using Vitamin B2…
- Trial name
- NCT05321043
- Testing
- Vitamin B2 labeling
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital