Clinical trials: Endoscopic Assessment, open to volunteers
Sleeve Gastrectomy
Powered Handle Primary Sleeve Gastrectomy Study
The objective of this prospective, single arm, single-center study is to evaluate patients who are undergoing primary sleeve gastrectomy procedures and are surgically treated with the AEON Endoscopic Powered Handle Stapler and…
- Trial name
- NCT06474637
- Testing
- AEON Endoscopic Powered Stapler Handle and Reload
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lexington Medical Inc.
Painless Gastrointestinal Endoscopy
A Clinical Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Capsules for Preoperative Preparation in Painless Gastrointestinal Endoscopy Procedures
Gastrointestinal endoscopy procedures, including upper gastrointestinal endoscopy and colorectal endoscopy, represent a fundamental and important method for examining and managing digestive tract diseases, with both diagnostic…
- Trial name
- NCT07271303
- Testing
- Hyoscine Butylbromide
- Volunteers
- 74 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Crohn Disease (CD), Ileocolic Resection
Evaluation of Therapeutic Strategy to Prevent Crohn's Disease Endoscopic poSToperatIve recurreNce Based on earlY Dosage of Faecal Calprotectin
Crohn's disease (CD) (> 200,000 patients in France) is a chronic inflammatory disease that can lead to progression of intestinal destruction and impaired quality of life.
- Conditions
- Crohn Disease (CD), Ileocolic Resection, Post-endoscopic Operative Reccurence
- Trial name
- DESTINY II (NCT06972901)
- Testing
- Early faecal calprotectin dosage
- Where
- 8 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Clermont-Ferrand
Unresectable Pancreatic Cancer, Advanced Pancreatic Cancer
Safety and Efficacy of NRT6008 in Patients With Unresectable Locally Advanced Pancreatic Cancer (LAPC) and Advanced Pancreatic Cancer With Lymph Node Metastases
This is a single arm, open label, multi-center phase I study, including phase Ia dose escalation and phase Ib dose expansion. Safety review committee (SRC) will be formed to monitor safety and efficacy data through the study.
- Conditions
- Unresectable Pancreatic Cancer, Advanced Pancreatic Cancer, Lymph Node Metastases
- Trial name
- NCT06278454
- Testing
- NRT6008 Injection + Systematic chemotherapy
- Where
- 6 sites in China
- Volunteers
- 58 people
- Sponsor
- Chengdu New Radiomedicine Technology Co. LTD.
Acute Pancreatitis
A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis
The goal of this clinical trial is to test the safety and effectiveness of a single dose of RABI-767 given by endoscopic ultrasound (EUS) guided peripancreatic injection in participants with predicted severe acute pancreatitis.
- Trial name
- NCT06080789
- Testing
- RABI-767
- Where
- 16 sites in United States, India
- Volunteers
- 36 people
- Sponsor
- Panafina, Inc.
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Evaluation,Efficacy,Safety
Evaluation of the Efficacy and Safety of Magnetically-controlled Capsule Gastroscopy for Postoperative Assessment in Elderly Patients and Patients With Underlying Diseases
The objective of this prospective, observational, controlled clinical study is to use magnetically-controlled capsule gastroscopy for postoperative assessment in elderly patients and patients with underlying diseases, to evaluate…
- Trial name
- NCT06029608
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Crohn Disease (CD), Ulcerative Colitis (UC)
IBD Biomarker Discovery and Validation Platform
The goal of this observational study is to establish a multicenter prospective clinical and biospecimen platform for biomarker discovery and validation in inflammatory bowel disease, including Crohn's disease and ulcerative…
- Conditions
- Crohn Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Diseases (IBD)
- Trial name
- IBD-BIOP (NCT07686406)
- Where
- 2 sites in China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Eosinophilic Gastritis, Gastroparesis
Study of Gastric Motility in Eosinophilic Gastritis
Purpose: The study is a cross-sectional observational study designed to determine if eosinophilic gastritis (EG) results in gastric motility impairment.
- Conditions
- Eosinophilic Gastritis, Gastroparesis, Gastric Motility Disorder
- Trial name
- OAT-FEED (NCT05229432)
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Postoperative Complications, Respiratory Depression
Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments
This study aims to evaluate the efficacy and safety of Remimazolam, either used alone or in combination with Propofol, for moderate sedation anesthesia during endoscopic therapies or examinations.
- Conditions
- Postoperative Complications, Respiratory Depression, Postoperative Nausea, Vomiting
- Trial name
- Remimazolam (NCT06777758)
- Testing
- Remimazolam, Propofol
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Spinal Instability
CLUBE (UBE Stability / Dynamic Radio)
Degenerative pathologies of the spine affect a large proportion of the increasingly ageing population, and are a major public health issue.
- Trial name
- NCT06904326
- Testing
- Postoperative dynamic radiography
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Clinique Saint Jean, France
Colorectal Cancer, Colonoscopy
ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos
With the participants help, the investigators aim to track treatment methods, treatment outcomes, and adverse events, as well as document the treatment strategies used during endoscopic colorectal cancer prevention and treatment.
- Conditions
- Colorectal Cancer, Colonoscopy, Polypectomy
- Trial name
- NCT06920680
- Where
- 2 sites in Germany
- Volunteers
- 1,834 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Rheumatoid Arthritis (RA
Dysphagia in Rheumatoid Arthritis
The primary goal of this cross-sectional study is to assess risk factors/predictors for dysphagia in RA. The secondary goals include demonstrating whether flexible fiberoptic pharyngolaryngoscopy can detect…
- Trial name
- NCT07401732
- Testing
- flexible fiberoptic pharyngolaryngoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Colorectal Neoplasms, Colonic Polyps
Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study
This prospective randomized controlled study aims to evaluate the diagnostic accuracy of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for detection and optical characterization of…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma, Serrated Polyps
- Trial name
- INSIGHT (NCT07797361)
- Testing
- White Light Endoscopy, Versatile Intelligent Staining Technology, Spectral Flexible Imaging
- Where
- Brazil
- Volunteers
- 990 people
- Sponsor
- Alexandre Vontobel Padoin
Esophageal Varices, Portal Hypertension
Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hypertension
Endoscopic esophageal variceal ligation combined with gastric variceal embolization using tissue glue is currently the first-choice method for preventing rebleeding in patients with cirrhosis and portal hypertension.
- Trial name
- NCT06970509
- Where
- 10 sites in China
- Volunteers
- 1,450 people
- Sponsor
- Shanghai Zhongshan Hospital
Pancreatic Diseases
Fine-needle Biopsy Combined With Macroscopic On-site Evaluation for Diagnosis of Solid Pancreatic Lesions
The goal of this clinical trial is to compare the diagnostic efficacy, core tissue acquisition ability, number of punctures and puncture time of macroscopic on-site evaluation (MOSE) and two punctures alone in Endoscopic…
- Trial name
- NCT06994611
- Testing
- MOSE application, Conventional processing
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Changhai Hospital
Familial Adenomatous Polyposis (FAP), Pouches, Ileoanal
Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL)
This international, multi-centre randomised controlled trial will compare dye-based chromoendoscopy with virtual chromoendoscopy, using NBI/BLI, for adenoma detection during routine surveillance pouchoscopy in adults with…
- Trial name
- ENDOPOL (NCT07726771)
- Testing
- Chromoendoscopy (Indigo Carmine), Virtual Chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- London North West Healthcare NHS Trust
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
Selective Median Lobe Surgery Outcomes Study
This prospective multicenter observational cohort study will evaluate clinical outcomes after selective median lobe transurethral surgery for benign prostatic obstruction.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH), Benign Prostatic Obstruction, Urinary Retention
- Trial name
- UNVEIL-BPO (NCT07699718)
- Testing
- Selective Median Lobe TURP, Selective Median Lobe HoLEP/AEEP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 420 people
- Sponsor
- Necmettin Erbakan University
Premalignant Conditions, Malignant Lesions
To Evaluate the Best Metric for Inspection Time During a Diagnostic and/or Surveillance Upper Gastrointestinal Endoscopy (Age ≥ 18 Years, Informed Consent), Between Total Inspection Time Versus Withdrawal Time, for the Identification of Malignant Lesions
Gastric cancer is the fifth cause of cancer-related mortality worldwide. Gastric carcinogenesis involves the progression from premalignant conditions such as atrophic gastritis and intestinal metaplasia to premalignant lesions…
- Conditions
- Premalignant Conditions, Malignant Lesions, Gastric, Esophageal
- Trial name
- NCT06696209
- Testing
- Analysis of the withdrawal time of the Upper Gastrointestinal Endoscopy, Analysis of the total time of the Upper Gastrointestinal Endoscopy, Upper gastrointestinal endoscopy: Common Practices
- Where
- Portugal
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Fistula, Regenerative Medicine
RESTOREGI Study: Regenerative Endoscopic Stromal Therapy: Outcomes and Risk Factor Evaluation in GI Fistulas
RESTOREGI Study Benign gastrointestinal fistulas are abnormal communications between the gastrointestinal tract and adjacent organs or the skin.
- Conditions
- Fistula, Regenerative Medicine, Stromal Vascular Fraction
- Trial name
- RESTORE-GI (NCT07661043)
- Testing
- Endoscopic tSVF-EM Therapy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Asian Institute of Gastroenterology, India