Clinical trials: Endoscopic Hemostasis
Peptic Ulcer Hemorrhage
Precise Delivery of Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding
Peptic ulcer bleeding is a common emergency for patients who need therapeutic endoscopy. According to international guidelines and Taiwan consensus, the standard therapy included proton pump inhibitor (PPI) and endoscopic…
- Trial name
- NCT05248321
- Testing
- Tranexamic Acid Powder
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Compare Ecchymosis and Edema for Fibrin Sealant and no Fibrin Sealant
Efficacy and Safety of Fibrin Sealant (FS) VH S/D-APR for Hemostasis and Wound Healing in Endoscopic Browlift
The primary objective is to evaluate the safety and efficacy of Artiss (Fibrin Sealant) in reducing the incidence of early postoperative bruising and swelling.
- Trial name
- NCT01320514
- Testing
- Fibrin Sealant (Artiss)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nguyen, Davis B., M.D.
Bleeding Peptic Ulcers
Hemostasis of Active Gastrointestinal (GI) Luminal Tract Bleeding
The objective of this study is to show that Hemospray is effective in achieving initial hemostasis and documenting rate of further bleed when compared to standard of care.
- Trial name
- HALT (NCT01306864)
- Testing
- Hemospray Kit
- Where
- 12 sites in Canada, Hong Kong and 2 more
- Volunteers
- 67 people
- Sponsor
- Cook Group Incorporated
Active Peptic Ulcer Disease/GI Bleeding
Efficacy of Hemostasis by Soft Coagulation Using Endoscopic Hemostatic Forceps for Acute Peptic Ulcer Bleeding
Endoscopic high-frequency soft coagulation is available for the management of bleeding or nonbleeding visible vessels during endoscopic submucosal dissection.
- Trial name
- NCT02020603
- Testing
- epinephrine injection plus soft coagulation using hemostatic forceps, epinephrine injection plus argon plasma coagulation
- Where
- South Korea
- Volunteers
- 151 people
- Sponsor
- Kyunghee University Medical Center
Biliary Obstruction, Complication of Treatment
Treatment of Postsphincterotomy Bleeding With a Novel Self-assembling Peptide Hemostatic Gel.
The aim of this observational study is to evaluate safety and efficacy of a novel self-assembling peptide hemostatic gel in reduction of bleeding after endoscopic sphincterotomy during ERCP (endoscopic retrograde…
- Trial name
- ERCPURA (NCT05886127)
- Testing
- A novel hemostatic agent (Purastat®)
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- General University Hospital, Prague
Bleeding After GI Endoscopy
Endoscopic Application of Hemostatic Drug Powder in Lower Gastrointestinal Bleeding: A Pilot Study
This clinical trial will enroll patients at National Cheng Kung University Hospital. All patients who are hospitalized for lower gastrointestinal bleeding and undergo colonoscopy will be invited to participate.
- Trial name
- NCT07679139
- Testing
- Tranexamic acid and sucralfate powder spray, Standard endsocopic hemostasis
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Hypertension, Hypotension
Intranasal Injection Versus Topical Administration of Epinephrin During Endoscopic Sinus Surgery
Intranasal injection of epinephrine is used routinely during endoscopic sinus surgery (ESS) to reduce bleeding in the nasal mucosa and thereby improve visualization of the surgical field.
- Conditions
- Hypertension, Hypotension, Tachycardia, Bradycardia
- Trial name
- NCT01075581
- Testing
- Epinephrin (Intranasal injection), Epinephrin (Topical administration)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Ulcer Bleeding
Second-look Endoscopy in High Risk Patients After Endoscopic Hemostasis to Their Bleeding Peptic Ulcers Improves Their Outcomes
Bleeding peptic ulcer is a common medical emergency. Endoscopic treatment stops bleeding in those actively bleeding from their peptic ulcers, reduces further bleeding, transfusion, surgery and deaths.
- Trial name
- NCT02352155
- Testing
- epinephrine injection or heater probe or hemoclips, Observation only
- Where
- 2 sites in China, Thailand
- Volunteers
- 157 people
- Sponsor
- Chinese University of Hong Kong
High-risk Patients for Post-ESD Bleeding
Efficacy of Hemostatic Powder in Preventing Bleeding After Gastric Endoscopic Submucosal Dissection in High-risk Patients: A Prospective Randomized Control Study
Endoscopic submucosal dissection (ESD) for superficial gastric neoplasm is minimally invasive and achieves curative resection with an acceptable rate of adverse events.
- Trial name
- NCT03169569
- Testing
- Endo-clot™ (EndoClot Plus, Unc., Santa Clara, CA, USA) group, Hemostatic forceps Only (Coagrasper®, Olympus, Japan) group
- Where
- South Korea
- Volunteers
- 143 people
- Sponsor
- Yonsei University