Clinical trials: Endoscopic Therapy
Pain
Effect of Virtual Endoscopy Simulator Training on Real Patient Endoscopy
Trainees (Residents in internal medicine), naive to real patient endoscopy, will be randomized to receive either 3 weeks/2 hours per day of structured training for a total of 20 hours on the virtual endoscopy simulator GI-Mentor…
- Trial name
- endosim (NCT00576043)
- Testing
- Simulator Training
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Medical University of Vienna
Unresectable Biliary Tract Carcinoma
Endoscopic Retrograde Cholangiopancreatography With Radiofrequency Ablation (ERCP-RFA) Combined With Envafolimab and Surufatinib Sequential Therapy for Unresectable Biliary Tract Carcinoma
The sequential treatment strategy of ERCP-RFA combined with envafolimab and surufatinib proposed in this study aims to maximally inhibit the progression of unresectable biliary tract tumors through the combined application of…
- Trial name
- NCT06656559
- Testing
- Envafolimab and Surufatinib
- Volunteers
- 30 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Pancreatic Cystic Neoplasm
Endoscopic Ultrasound-Guided Chemoablation for the Treatment of Pancreatic Cystic Neoplasms
This phase II trial tests the effect of endoscopic ultrasound (EUS)-guided chemoablation in treating patients with pancreatic cysts.
- Trial name
- ERASE-Chemo (NCT07529483)
- Testing
- Ablation Therapy, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Stomach Neoplasms
Water-jet Assisted ESD vs Conventional ESD Technique for Treating Early Gastric Cancer
1. Introduction The aim of the study is to evaluate the efficacy and safety of ESD by use of a new water-jet assisted ESD system using the HybridKnife® in patients with early gastric neoplastic lesions in comparison to the…
- Trial name
- NCT01943253
- Testing
- Conventional ESD, Hybridknife ESD
- Where
- Germany
- Volunteers
- 117 people
- Sponsor
- Shanghai Zhongshan Hospital
Esophageal Achalasia
Routine Versus Symptomatic Protein Pump Inhibitor Therapy for Prevention of Gastroesophageal Reflux After Per Oral Endoscopic Myotomy for Esophageal Achalasia
Per Oral Endoscopic Myotomy (POEM) is a treatment of choice for achalasia with an excellent safety and efficacy profile. There is a high rate of esophagitis related to gastroesophageal reflux following this procedure.
- Trial name
- IPPOEM (NCT05899842)
- Testing
- Protein pump inhibitor therapy systematically
- Where
- 4 sites in France
- Volunteers
- 132 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
High-risk Patients for Post-ESD Bleeding
Efficacy of Hemostatic Powder in Preventing Bleeding After Gastric Endoscopic Submucosal Dissection in High-risk Patients: A Prospective Randomized Control Study
Endoscopic submucosal dissection (ESD) for superficial gastric neoplasm is minimally invasive and achieves curative resection with an acceptable rate of adverse events.
- Trial name
- NCT03169569
- Testing
- Endo-clot™ (EndoClot Plus, Unc., Santa Clara, CA, USA) group, Hemostatic forceps Only (Coagrasper®, Olympus, Japan) group
- Where
- South Korea
- Volunteers
- 143 people
- Sponsor
- Yonsei University
Obesity
Safety, Tolerability, and Sustained Weight Loss of Endoscopic Sleeve Gastroplasty With Diet Modification and Exercise
The purpose of this study is to compare the effect of endoscopic sleeve gastroplasty (ESG) with diet and exercise, to diet and exercise alone, to see which is better in weight loss reduction.
- Trial name
- NCT03206905
- Testing
- Endoscopic Sleeve Gastroplasty, Diet and Exercise
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Weill Medical College of Cornell University
GERD
Study of the NDO Endoscopic Plication System For the Treatment of Symptomatic Gastroesophageal Reflux Disease
The purpose of this prospective, multicenter study was to evaluate the safety and efficacy of endoscopic full-thickness plication for the treatment of symptomatic gastroesophageal reflux.
- Trial name
- NCT00587522
- Testing
- NDO Full-thickness Plicator
- Where
- 7 sites in United States, Canada
- Volunteers
- 64 people
- Sponsor
- NDO Surgical, Inc.
Gastrointestinal Vascular Malformation
the Efficiency of Endoscopic Treatment for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation
Gastrointestinal vascular malformation (GIVM), which is an important cause of acute or chronic gastrointestinal bleeding, consequently is in dire of effective treatment.
- Trial name
- NCT02716545
- Testing
- balloon assisted enteroscopy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Chronic Rhinosinusitis, Sinusitis
Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study
This investigation is a prospective, multi-institutional cohort study comparing the differences in health-related quality-of-life (HRQoL) improvements between subjects electing continued medical management for chronic…
- Trial name
- NCT01255566
- Where
- 3 sites in United States
- Volunteers
- 186 people
- Sponsor
- Oregon Health and Science University
Ulcer Hemorrhage
New Technologies for Endoscopic Treatment of Bleeding Gastroduodenal Ulcers
The purpose of the study was to improve treatment results of patients with bleeding gastroduodenal ulcers by endoscopic applications of autoplasma, enriched with platelets and granular sorbent aseptisorb-A.
- Trial name
- NCT04239118
- Testing
- Complex endoscopic treatment with the use of granular sorbent aseptisorb-A and autoplasm enriched with platelets, Traditional methods of endoscopic hemostasis
- Where
- Russia
- Volunteers
- 112 people
- Sponsor
- Voronezh N.N. Burdenko State Medical Academy
Gastric Low Grade Intraepithelial Neoplasia
Hybrid APC for Gastric Low Grade Intraepithelial Neoplasia
This cohort study aims to investigate the clinical efficacy and safety of Hybrid APC for treatment of gastric low grade intramucosal neoplasia.
- Trial name
- HybridAPC (NCT04197180)
- Testing
- Hybrid Argon Plasma Coagulation
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Treatment Related Cancer
Pancreatic Cyst Ablation With a Monopolar Radiofrequency Ablation Probe
Pancreatic cysts (A cyst is a thin walled cavity containing fluid) were rarely reported previously, but have been on a rise due to advanced imaging for evaluating pancreatic lesions or other medical reasons has increased…
- Trial name
- NCT04253249
- Where
- United States
- Sponsor
- Baylor College of Medicine