Clinical trials: Endoscopic Ultrasound
Pancreas Neoplasms, Lymphatic Metastasis
Prospective Multi-center, Single Blinded, Randomized, Controlled Trial of EUS-FNB and EUS-FNA on Solid Occupying Lesion
The purpose of this study is to compare the diagnosis accuracy of FNA and FNB biopsy on pancreatic, retroperitoneal, mediastinum and pelvic cavity solid occupying lesions.
- Conditions
- Pancreas Neoplasms, Lymphatic Metastasis, Neoplasm Metastases, Unknown Primary Neoplasm Metastasis
- Trial name
- NCT02327065
- Testing
- EUS-FNA (EchoTip Ultra), EUS-FNB (EchoTip ProCore)
- Where
- China
- Volunteers
- 408 people
- Sponsor
- Huazhong University of Science and Technology
Pancreatic Cancer, Pancreas Disease
Artificial Intelligence in Endoscopic Ultrasound
The objective of the study is to determine if this artificial intelligence system is capable of detecting abnormalities in the pancreas that are identified by an endoscopist at endoscopic ultrasound procedures.
- Conditions
- Pancreatic Cancer, Pancreas Disease, Pancreatic Cyst
- Trial name
- NCT06564571
- Testing
- Patients undergoing endoscopic ultrasound procedures
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Orlando Health, Inc.
Gastroenterology, Lesions
Evaluation of Diagnostic Yield of EUS-Guided Tissue Sampling
All patients will receive standard medical care and no experimental interventions will be performed. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a well-established procedure commonly used for the…
- Trial name
- NCT02979509
- Testing
- Endoscopic ultrasound- (EUS) guided tissue sampling
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Florida
Malignant Biliary Obstruction
Percutaneous Transhepatic Cholangiography Versus Endoscopic Ultrasound Guided Biliary Drainage
Patients with obstructive jaundice due to locally advanced/metastatic malignancy with dilated intrahepatic bile ducts will be recruited from the department of Gastroenterology and Hepatology at the University Hospital of Leuven.
- Trial name
- PETRUS (NCT01686425)
- Testing
- Percutaneous transhepatic cholangiography vs. endoscopic biliary drainage
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pancreatic Disease
EUS Ductal Evaluation in One Endoscopic Session for the Diagnosis of Exocrine Pancreas Disease
The purpose of this study is, to develop a standard of care protocol using the combination of EUS, ePFT, and sEUS during one endoscopic session (instead of the three separate endoscopic sessions).
- Trial name
- NCT01997476
- Testing
- Combined EUS, e-PFT and sEUS Testing
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pancreatic Carcinoma, Pancreatic Neuroendocrine Tumor
Study on Microflora Characteristics of Pancreatic Solid Lesions Via Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
Study objective: To describe the microflora characteristics of the pancreatic solid lesions via the tissue acquired via the endoscopic ultrasound-guided fine needle aspiration/biopsy (EUS-FNA/B).
- Conditions
- Pancreatic Carcinoma, Pancreatic Neuroendocrine Tumor, Autoimmune Pancreatitis, Microflora
- Trial name
- NCT05171517
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Preoperative Fasting
Gastric Emptying After a Yoghurt Breakfast in Children: a Pilot Study
Children are asked to fast before anaesthesia to reduce the amount of material remaining in the stomach. Prolonged fasting can cause hunger, thirst and discomfort.
- Trial name
- PREFACT (NCT07866014)
- Testing
- Three-hour fasting after yoghurt breakfast, Four-hour fasting after yoghurt breakfast
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Post-surgical Intra-abdominal Collection
Retrospective Study of Endoscopic Ultrasound (EUS) Guided Transmural Drainage of Post-operative Abdominal Collections
This is a retrospective study of a single center on endoscopic ultrasound (EUS) guided transmural drainage of post-operative collections during a 9 years period.
- Trial name
- NCT01537848
- Testing
- EUS guided transmural drainage
- Where
- Belgium
- Volunteers
- 43 people
- Sponsor
- Erasme University Hospital
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Pancreatic Neoplasms
Discovery of Soluble Biomarkers for Pancreatic Cancer Using Innovative All-Patient Inclusive Methodology
Pancreatic ductal adenocarcinoma (PDAC) remains among cancers with a very poor prognosis (1-year survival <20%). Endoscopic ultrasound with fine needle aspiration (EUS/FNA) is the common examination for all patients with…
- Trial name
- PanEXPEL2 (NCT04370574)
- Testing
- Soluble Biomarkers dosage
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Pancreatic Masses
RCT Comparing Accuracy Among Franseen, Forward-bevel Westcott, and Fork-tip EUS-FNB Needle in Diagnosis of Solid Pancreatic Lesions
Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) is a well-established technique for pancreatic tissue acquisition, offering a high diagnostic accuracy ranging from 78% to 95%, along with a favorable safety profile.
- Trial name
- NCT07032974
- Testing
- Franseen, Forward-bevel, Fork-tip
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Pancreatic Fluid Collection, Pancreatitis
WONDER-02 Trial: Plastic Stent vs. Lumen-apposing Metal Stent for Pancreatic Pseudocysts
Endoscopic ultrasound (EUS)-guided transluminal drainage has become a first-line treatment modality for symptomatic pancreatic pseudocysts.
- Conditions
- Pancreatic Fluid Collection, Pancreatitis, Pancreatic Pseudocyst
- Trial name
- NCT06133023
- Testing
- Plastic stent, LAMS
- Where
- 26 sites in Japan
- Volunteers
- 80 people
- Sponsor
- Tokyo University
Subepithelial Gastrointestinal Tumors
SUNNYDAY: SUbepithelialgastroiNtestiNal Tumors Detection,accuracYDiAgnosis,ElastographY and Contrast-enhanced EUS
This will be a longitudinal, prospective, observational multicenter study where the role of EUS-E will be examined in differentiating subepithelial gastrointestinal tumors in 138 patients
- Trial name
- SunnyDay021 (NCT06324032)
- Testing
- EUS Elastography (EUS-E)
- Where
- 7 sites in Italy
- Volunteers
- 138 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Cancer
Endoscopic Ultrasound-Guided Fiducial Placement for Stereotactic Body Radiotherapy
The purpose of this research study is to evaluate placing the radiation therapy markers (Fiducial) by using an endoscopic procedure. The endoscopic procedure is called an Endoscopic Ultrasound (EUS).
- Trial name
- NCT01671163
- Testing
- Endoscopic Ultrasound (EUS) for fiducial placement
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Florida
Bile Duct Diseases
The Role of Endoscopic Ultrasound in Evaluation of Patients With Indefinite Cause of Bile Duct Dilatation
In the era of diagnostic imaging advances, Bile Duct Dilatation becomes a common incidental finding in patients present with either gastrointestinal symptoms or undergone the imaging study for any other complaints.
- Trial name
- NCT05475964
- Testing
- Endoscopic ultrasound
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HMHamed
Esophageal Neoplasms Malignant
Multimodal Endoscopic Image Fusion for Assessing Infiltration in Superficial Esophageal Squamous Cell Carcinoma
The objective of this project is to pioneer a novel protocol for the adjunctive screening of early-stage esophageal cancer and its precancerous lesions.
- Trial name
- NCT06412419
- Testing
- Magnifying Endoscopy and Endoscopic Ultrasonography
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Changhai Hospital
Cirrhosis, Vascular Diseases
Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements
Portal hypertension (PHT) is the main consequence of advanced chronic liver diseases (ACLD) and is often associated with severe complications leading to increased morbidity and mortality.
- Trial name
- EUSPREM (NCT06216509)
- Testing
- Endoscopic ultrasound pressure measurement
- Where
- Romania
- Volunteers
- 50 people
- Sponsor
- Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor
Malignant Biliary Obstruction, Pancreatic Cancer
EUS-guided CDS vs ERCP as First Line in Malignant Distal Obstruction in Borderline Disease (CARPEDIEM-2 Trial)
The aim of this clinical trial is to evaluate temporal delay (days) between biliary drainage (EUS-CDS vs ERCP as first line therapy) and chemotherapy start in patients with borderline distal malignant biliary obstruction.
- Conditions
- Malignant Biliary Obstruction, Pancreatic Cancer, Biliary Tract Neoplasms
- Trial name
- NCT06375954
- Testing
- Endoscopic biliary drainage, Self-expandable metallic stent (SEMS), Lumen-apposing metal stent (LAMS) and double-pigtail plastic stent (DPPS)
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Hospital Universitari de Bellvitge
Gastric Tumor, Early Gastric Cancer
Endoscopic Ultrasonographic Staging and Conventional Endoscopic Staging for Depth of Invasion for Early Gastric Cancer
The accurate prediction of depth of tumor invasion in early gastric cancer is essential for the proper selection of candidates for endoscopic resection.
- Trial name
- NCT01832246
- Where
- South Korea
- Volunteers
- 560 people
- Sponsor
- Seoul National University Hospital
Obstructive Jaundice, Pancreatic Cancer
Endoscopic Ultrasound-guided Biliary Drainage for Malignant Biliary Obstruction After Failed ERCP
In this study the investigators retrospectively report outcomes of direct transluminal EUS-BD in a series of patients with malignant biliary obstruction after failed ERCP as the experience of a single Italian center
- Trial name
- (EUS-BD) (NCT03510754)
- Testing
- Eus guided biliary drainage
- Volunteers
- 36 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS