Clinical trials: Endoscopy, Digestive System
Ulcerative Colitis (UC), Crohn Disease (CD)
Fluorescence Imaging of Risankizumab-800CW in Inflammatory Bowel Disease
Crohn\'s Disease (CD) and Ulcerative Colitis (UC) are chronic inflammatory bowel diseases (IBD). Risankizumab is a human monoclonal antibody against IL23 p19, part of a pro-inflammatory cytokine that mediates the inflammatory…
- Trial name
- NAVIGATE (NCT06606808)
- Testing
- Risankizumab-800CW 4.5 mg, Risankizumab-800CW 15 mg, Risankizumab-800CW 25 mg
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- University Medical Center Groningen
Common Bile Duct Stone, Abdominal Massage
Effect of Abdominal Massage on Prevention of Recurrent Common Bile Duct Stones After Endoscopic Sphincterotomy
Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (EST) are the preferred techniques for treating common bile duct stones (CBDS) due to their advantages of minimal trauma, rapid recovery, low…
- Trial name
- NCT05892458
- Testing
- Abdominal massage
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Air Force Military Medical University, China
Colon Cancer, Colon Polyp
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the…
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma
- Trial name
- NCT03462706
- Testing
- Cold Snare, Hot Snare, Cold EMR
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gastric Outlet Obstruction
Magnetic Anastomosis Device Relief of Malignant Gastric Outlet Obstruction
The purpose of this study is to determine if the Cook Magnetic Anastomosis Device can be used to safely and successfully create a patent gastrojejunal anastomosis in subjects requiring treatment of gastric outlet obstruction…
- Trial name
- MAD (NCT00487552)
- Testing
- Cook Magnetic Anastomosis Device (MAD) with Stent
- Where
- 4 sites in Belgium, Italy and 1 more
- Volunteers
- 18 people
- Sponsor
- Cook Group Incorporated
Pancreatic Disease
Endoscopic Ultrasound-guided Fine-needle Aspiration of Solid Pancreatic Lesions With Rapid Staining of Cytological Smears Followed by Whole Slide Scanning and Artificial Intelligence Diagnosis: A Prospective, Multicenter Study.
The objective of this observational study is to investigate whether the self-developed whole slide scanning and artificial intelligence diagnostic system for pancreatic solid lesion puncture cytopathology (hereinafter referred to…
- Trial name
- NCT06824909
- Testing
- ROSE-AI diagnostic system
- Where
- 2 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Ruijin Hospital
Gastrointestinal Neoplasm
Prospective Cohort Study on the Safety and Efficacy of Endorobotics for Endoscopic Submucosal Dissection (Endorobotics ESD)
This trial is a prospective, single arm study of 30 patients recruited to undergo endoscopic submucosal dissection (ESD) with a novel robotic assisted technology.
- Trial name
- NCT06726798
- Testing
- Endoscopic submucosal dissection with EndoRobotics traction device
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Pancreatic Cancer
Training Endoscopists to Perform On-site Rapid Cytological Evaluation for EUS-FNA of Solid Pancreatic Lesions
In China, there is a serious shortage of pathologists who can perform on-site cytological diagnosis. As a result, there are few centers that can conduct ROSE in China, which limits the diagnostic accuracy of EUS-FNA to a certain…
- Trial name
- EUS-FNA (NCT04509687)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changhai Hospital
Stomach Diseases, Small Intestine Disease
Magnetically Controlled Capsule Endoscopy in Visualization of the UGI and Small Intestine
In this study, we retrospectively analyzed the videos of combined upper digestive tract and small intestine examination under MCE, so as to clarify the feasibility and diagnostic efficacy of MCE in one-time examination of the…
- Trial name
- NCT05069233
- Testing
- UGI+SB
- Where
- China
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Rejection of an Intestine Transplant
Surveillance of Allograft Rejection After Intestinal Transplantation Using Endoscopy
Intestinal failure (IF) which are characterized by inadequate maintenance of nutrition via normal intestinal function comprises a group of disorders with many different causes.
- Trial name
- NCT03616548
- Testing
- Endoscopic surveillance
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Far Eastern Memorial Hospital
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Pancreatic Cancer
Prospective Evaluation of Diagnostic Accuracy of Endoscopic Ultrasound-guided Fine Needle Aspiration and Biopsy (EUS-FNAB) in the Absence of Rapid Onsite Evaluation
<Background/aims> Rapid onsite evaluation (ROSE) of endoscopic ultrasound-guided fine needle aspiration and biopsy (EUS-FNAB) specimens by attending cytopathologists has been demonstrated to improve diagnostic yields of EUS-FNAB.
- Trial name
- FNASROSE (NCT02079285)
- Testing
- EUS-FNA
- Where
- 2 sites in South Korea
- Volunteers
- 75 people
- Sponsor
- Kangbuk Samsung Hospital
Gastric Outlet Obstruction, Biliary Obstruction
Prospective Registry Of Therapeutic EndoscopiC ulTrasound
This registry aims to analyze long-term outcomes of therapeutic EUS (T-EUS) procedures, as well as to describe clinical and technical variables potentially predicting clinical success or adverse events, for a better selection of…
- Conditions
- Gastric Outlet Obstruction, Biliary Obstruction, Acute Pancreatic Fluid Collection, Acute Pancreatitis With Infected Necrosis
- Trial name
- PROTECT (NCT04813055)
- Testing
- Therapeutic EUS, Percutaneous Procedures, Surgical Interventions
- Where
- Italy
- Volunteers
- 510 people
- Sponsor
- Paolo Giorgio Arcidiacono, MD
Familial Adenomatous Polyposis (FAP), Pouches, Ileoanal
Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL)
This international, multi-centre randomised controlled trial will compare dye-based chromoendoscopy with virtual chromoendoscopy, using NBI/BLI, for adenoma detection during routine surveillance pouchoscopy in adults with…
- Trial name
- ENDOPOL (NCT07726771)
- Testing
- Chromoendoscopy (Indigo Carmine), Virtual Chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- London North West Healthcare NHS Trust
Gastro -Oesophagal Reflux, Laryngo-pharyngeal Reflux
European TIF2.0 Registry
This is a European, multi-centre, prospective registry that aims to determine the safety and efficacy of transoral incisionless fundoplication, with or without concomitant hiatal hernia repair, for the treatment of patients with…
- Trial name
- EURO-TIF (NCT07395219)
- Testing
- Transoral incisionless fundoplication with or without concomitant hiatal hernia repair with the EsophyX device
- Where
- 7 sites in Austria, Italy and 5 more
- Volunteers
- 500 people
- Sponsor
- Cleveland Clinic London
Morning Inspections, Afternoon Inspections
Comparison of Receiving Painless Gastrointestinal Endoscopy in the Morning or Afternoon on Postoperative Sleep Quality
Gastrointestinal endoscopy (GIE) are important examinations for screening, diagnosing, and treating a variety of gastrointestinal diseases.
- Conditions
- Morning Inspections, Afternoon Inspections, Sleep Quality, Gastrointestinal Endoscopy
- Trial name
- NCT04879771
- Testing
- Receive gastrointestinal endoscopy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Achalasia, EGJ Outflow Obstruction
Safety and Efficacy of a Novel SpydrBlade Flexible Bipolar in POEM
Achalasia is an idiopathic motility disorder, primarily identified by the absence of esophageal peristalsis and the inability of the lower esophageal sphincter (LES) to relax properly.
- Trial name
- NCT07406945
- Testing
- SpydrBlade Flex
- Where
- 2 sites in Ecuador, Hong Kong
- Volunteers
- 73 people
- Sponsor
- Chinese University of Hong Kong
Pancreatitis
Post ERCP Pancreatitis Prevention in Average Risk Patients
Diclophenac potassium and ceftazidime are commercially available drugs that are used in various clinical situations. They are safe and known for years.
- Trial name
- NCT01784445
- Testing
- Ceftazidime
- Where
- Croatia
- Volunteers
- 124 people
- Sponsor
- University Hospital Rijeka
Gastrointestinal Neoplasms, Abnormality of Enteric Nervous System Morphology
Endoscopic Vital Nerve Staining in Gastrointestinal Diseases
In this study, methylene blue (MB) was used as vital nerve staining agent. During gastroenteroscopy, mucosal nerve staining was achieved by endoscopic submucosal injection of MB solution.
- Trial name
- NCT05232357
- Testing
- Sodium thiosulfate and Methylene blue solution
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Inflammatory Bowel Diseases, Children, Only
A Treat-to-target Strategy Using Pan-enteric Capsule Endoscopy (PCE) in Paediatric Crohn's Disease (CD).
This prospective, interventional study aims this to determine the efficacy and safety of a PCE-based treat-to-target strategy in order to achieve Mucosal Healing (MH) and deep remission (DR) of pediatric Crohn's Disease (CD) over…
- Trial name
- PCE (NCT03161886)
- Testing
- Pan-enteric Capsule Endoscopy (PCE)
- Volunteers
- 48 people
- Sponsor
- Azienda Policlinico Umberto I
Capsule Endoscopy, Cancer of Stomach
Medical Consortium for Screening Upper Gastrointestinal Cancers With Magnetically Controlled Capsule Gastroscopy
The aim of our study was to demonstrate the efficacy and feasibility of the medical consortium for screening upper gastrointestinal cancers with magnetically controlled capsule gastroscopy.
- Conditions
- Capsule Endoscopy, Cancer of Stomach, Cancer of Esophagus, Health Policy
- Trial name
- NCT04032353
- Testing
- Medical Consortium
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Yanqing Li