Clinical trials: Endosonography
Portal Hypertension, Chronic Liver Disease (CLD)
EUS-guided Portal Pressure Gradient (PPG) Measurement: a Potential Alternative to the Traditional HVPG
The goal of this investigator-initiated, single-arm, prospective study is to evaluate the accuracy, safety, and feasibility of endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) measurement as a potential alternative…
- Conditions
- Portal Hypertension, Chronic Liver Disease (CLD), Cirrhosis
- Trial name
- EUS-PPG (NCT06863012)
- Testing
- Endoscopic Ultrasound-Guided Portal Pressure Gradient (EUS-PPG) Measurement, Hepatic Venous Pressure Gradient (HVPG) Measurement
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundacio Privada Mon Clinic Barcelona
Walled Off Necrosis
To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON Drainage
In adults with walled-off pancreatic necrosis (WON) undergoing endoscopic ultrasound (EUS)-guided transluminal necrosectomy, does early removal of the lumen-apposing metal stent (LAMS) (at 2 weeks or immediately after the last…
- Trial name
- STEP1 (NCT07307248)
- Testing
- Standard LAMS Removal with Double-Pigtail Plastic Stent, Standard LAMS Removal without DPT
- Where
- India
- Volunteers
- 408 people
- Sponsor
- Asian Institute of Gastroenterology, India
Pancreatitis, Chronic, Abdominal Pain
Clinical Trial to Evaluate the Endoscopic Ultrasound Guided Celiac Plexus Block for Treatment of Pain in Chronic Pancreatitis
AIM: To compare pain relief in patients randomly assigned to endoscopic ultrasound-guided celiac ganglia block (EUS-CGB) vs standard endoscopic ultrasound-guided celiac plexus block (EUS-CPB).
- Trial name
- NCT03070210
- Testing
- EUS-celiac ganglia block (EUS-CGB), EUS-celiac plexus block (EUS-CPB)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- The Cleveland Clinic
Pancreatic Ductal Adenocarcinoma
A Clinical Study to Evaluated Which Number of Passes of EUS-FNB is Better for Culturing Primary Cells of PDAC
The Aim of this study is to investigate the amount of tissue required for the successful culture of primary cells from human-derived pancreatic ductal adenocarcinoma which obtained by endoscopic ultrasound-guided fine-needle…
- Trial name
- NCT04794140
- Testing
- different number of passes
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Liver Biopsy
Endoscopic Ultrasound vs Percutaneous Route for Liver Biopsy
This study is to evaluate and directly compare the technical success, tissue quality, diagnostic efficacy and safety profile of Percutaneous and Endoscopic Ultrasound-guided Liver Biopsy.
- Trial name
- NCT04003766
- Testing
- biopsy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AdventHealth
Hilar Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma (Icc)
Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)
In the POELH-II trial (Clinicaltrials.gov ID NCT05678218) patients with presumed resectable perihilar (pCCA), intrahepatic (iCCA) or mid-common bile duct (CBD) cholangiocarcinoma had the outcomes of their preoperative endoscopic…
- Conditions
- Hilar Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma (Icc), Cholangiocarcinoma, Perihilar Cholangiocarcinoma
- Trial name
- POELH-III (NCT07161869)
- Testing
- Registration of all findings during preoperative Endoscopic Ultrasound
- Where
- 6 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Erasmus Medical Center
Pancreatic Tumors
Standard Versus Fanning Techniques for Endoscopic Ultrasound-Fine Needle Aspiration (EUS-FNA)
Endoscopic Ultrasound (EUS)-guided biopsy is the most ideal technique for evaluating a growth in the pancreas. EUS-guided biopsies yield a definitive diagnosis in greater than 80% of cases.
- Trial name
- NCT01501903
- Testing
- Standard, Fanning
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Shyam Varadarajulu
Pancreatic Cancer, Secondary Malignant Neoplasm of Lymph Node
Clinical Impact of EUS Elastography Mean Strain Histograms (SH) and Contrast Peak-enhancement in Focal Pancreatic Masses and Lymph Nodes
The study protocol is based on a multi-center semi-quantitative approach of EUS elastography data in combination with contrast-enhanced EUS, consisting of measuring SR and SH for focal pancreatic masses and lymph nodes, as well…
- Conditions
- Pancreatic Cancer, Secondary Malignant Neoplasm of Lymph Node, Benign Neoplasm of Lymph Nodes, Benign Pancreatic Tumors
- Trial name
- ADVEUS (NCT02459041)
- Testing
- Elastography, contrast enhancement
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- University of Medicine and Pharmacy Craiova
Prehepatic Portal Hypertension
EUS-Guided Portal Pressure Gradient Measurement in Prehepatic Portal Hypertension
Portal hypertension caused by prehepatic vascular obstruction, such as portal vein thrombosis or portal vein tumor thrombosis, represents a unique hemodynamic condition in which conventional hepatic venous pressure gradient…
- Trial name
- NCT07782554
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neoplasms, Biliary Stricture
The Diagnostic Value of Combinatory EUS and ERCP in Unclear Lesions
ERCP with brush cytology has a poor to moderate accuracy in unclear biliary lesions. Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) for cytology may override some of these shortcomings.
- Conditions
- Neoplasms, Biliary Stricture, Biliary Tract Neoplasms, Biliary Tract Diseases
- Trial name
- NCT03504293
- Testing
- Combinatory EUS and ERCP
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Sahlgrenska University Hospital
Pancreatic Neoplasms
Rapid On-Site Evaluation (ROSE) by Endosonographer: for Whom, When and by Whom?
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a highly sensitive and specific method in diagnosing solid pancreatic lesions.
- Trial name
- NCT04002778
- Testing
- Fine needle aspiration, Rapid on-site evaluation
- Volunteers
- 66 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Acute Cholecystitis
One-year Outcomes by Index Treatment in Elderly Patients With Acute Cholecystitis
Background: The GOLDENEYE study is an international, multicenter, prospective observational investigation designed to compare the outcomes of various management strategies for acute cholecystitis in patients aged 70 years and…
- Trial name
- GOLDENEYE (NCT07006298)
- Where
- Spain
- Volunteers
- 376 people
- Sponsor
- Instituto de Investigación Sanitaria y Biomédica de Alicante
Chronic Pancreatitis, Pancreatic Cancer
A Prospective Study of EUS Guided Celiac Block
The purpose of this prospective study is to measure the clinical effectiveness of EUS-guided CB in subjects, 50 who have chronic pancreatitis and 50 who have pancreatic cancer, that are already undergoing celiac block for…
- Trial name
- NCT00583271
- Testing
- triamcinolone, 98% dehydrated alcohol
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Indiana University
Biliary Disease, Pancreatitis
Los Angeles Prospective GI Biliary and EUS Series
Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound are increasingly being used to manage complex disease of the bile duct, pancreas and cancer.
- Conditions
- Biliary Disease, Pancreatitis, Gastrointestinal Neoplasms
- Trial name
- NCT02196935
- Testing
- clinical course
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- University of Southern California
Pancreatic Cancer
EUS- and US- Guided Biopsy for Pancreatic Lesion
Endoscopic ultrasound (EUS) and ultrasound (US) are the two primary imaging modalities used to guide pancreatic needle biopsy. This study aimed to compare the diagnostic performance and complications associated with EUS- and…
- Trial name
- NCT07138976
- Testing
- sampling tissue
- Volunteers
- 2,517 people
- Sponsor
- Tian'an Jiang
Portal Hypertension, Chronic Liver Disease
EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement
This study will directly compare the endoscopic ultrasound guided approach to obtain adequate liver biopsies and portal pressure gradient measurements to the current standard of care which uses the transjugular approach.
- Conditions
- Portal Hypertension, Chronic Liver Disease, Cirrhosis
- Trial name
- NCT05118308
- Testing
- Transjugular hepatic venous pressure gradient measurement with liver biopsy, Endoscopic ultrasound portal pressure gradient measurement with liver biopsy
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Portal Hypertension, Chronic Liver Disease
Within-Session Repeatability of EUS-Guided Portal Pressure Gradient Measurement
This prospective multicentre observational reliability study will determine how much a repeated endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) measurement differs from the first measurement in the same patient…
- Conditions
- Portal Hypertension, Chronic Liver Disease, Liver Cirrhosis
- Trial name
- REPEAT-PPG (NCT07877298)
- Testing
- Repeated EUS-Guided Portal Pressure Gradient Measurement
- Where
- 5 sites in Belgium, Canada and 2 more
- Volunteers
- 150 people
- Sponsor
- University Hospital Muenster
Nonfunctional Pancreatic Neuroendocrine Tumor, Pancreatic Neuroendocrine Tumor
EUS-FNI for Nonfunctional Pancreatic Neuroendocrine Tumors
The current study aims to access the feasibility, safety, and efficacy of EUS-FNI for nonfunctional pNETs
- Conditions
- Nonfunctional Pancreatic Neuroendocrine Tumor, Pancreatic Neuroendocrine Tumor, Endoscopic Ultrasound
- Trial name
- NCT05566093
- Testing
- EUS-guided ethanol ablation, EUS-guided lauromacrogol ablation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangxi Medical University
Carcinoma, Non-Small-Cell Lung
Assessment of Surgical sTaging vs Endoscopic Ultrasound in Lung Cancer: a Randomized Clinical Trial (ASTER Study)
Lung cancer is one of the most prevalent cancers and has a very high mortality. Both treatment and prognosis depend on the staging.
- Trial name
- NCT00432640
- Testing
- Endoscopic ultrasound staging, Surgical staging
- Where
- 4 sites in Belgium, Netherlands and 1 more
- Volunteers
- 240 people
- Sponsor
- University Hospital, Ghent
Cholecystitis, Acute
Hong Kong Follow up Protocol After EUS Gallbladder Drainage for Acute Cholecistitis
This study evaluates the long-term safety and efficacy of the Hong Kong follow up protocol in patients who will undergo drainage of the gallbladder under endoultrasonography (EUS) guidance in patients with acute cholecistitis not…
- Trial name
- NCT04874103
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Catholic University of the Sacred Heart