Clinical trials: Endothelial Dysfunction
- Condition Endothelial Dysfunction
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Endothelial Dysfunction
Bioefficacy of Phenolic Acids
The objective is to demonstrate the effect of phenolic acids on endothelial function.
- Trial name
- NCT01781559
- Testing
- phenolic acid
- Where
- Australia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Endothelial Dysfunction
Evaluation of a New Non-Invasive Device for Detection of Endothelial Dysfunction
The purpose of the study is to investigate the sensitivity and specificity of the Endotect compared with an ultrasound device in a flow-mediated vasodilatation (FMD) test.
- Trial name
- NCT00650741
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lavi Cardiatec
Endothelial Dysfunction, Hyperhomocysteinemia
Effect of L-Arginine and Pycnogenol on Light to Moderate Hypertension and Endothelial Function
The effect of a combination product (Verum ) with L-arginine, Pycnogenol, vitamin K2, R-(+)-alpha-lipoic acid and vitamins B6, B12 and folic acid is investigated in a double blind placebo-controlled cross-over study.
- Conditions
- Endothelial Dysfunction, Hyperhomocysteinemia, Hypertension Grade I, Subgroup "Borderline" (WHO)
- Trial name
- NCT02392767
- Testing
- Verum
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dr. Loges & Co. GmbH
Diabetic Macular Edema
First-In-Human Study of CU06-1004 Following Single and Multiple Ascending Doses in Healthy Volunteers
This clinical trial is the first-in-human study of CU06-1004. The purpose of this phase 1 study is to assess the safety and tolerability of single and multiple ascending oral doses of CU06-1004 in healthy adult subjects.
- Trial name
- NCT04795037
- Testing
- CU06-1004, Single dose, CU06-1004, Multiple doses
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Curacle Co., Ltd.
Chronic Fatigue Syndrome, Long COVID
Endothelial Dysfunction in Post-infection Fatigue Syndromes
Post-infection chronic fatigue syndromes, such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID-19 condition (Long Covid), are conditions primarily characterized by debilitating fatigue.
- Trial name
- NCT06463106
- Where
- Austria
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Endothelial Dysfunction
Effect of Chlorogenic Acids on the Human Vasculature
This study evaluates effects of different doses of chlorogenic acids on vascular health.
- Trial name
- NCT03520452
- Testing
- Green coffee extract
- Where
- Australia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Volunteers
The Impact of Intravenous Bendavia™ on Endothelial Reactivity Dysfunction in Cigarette Smoking
This will be a phase 1 randomized, double-blind, 2-period, 2-sequence crossover trial enrolling 6 healthy volunteers to assess the impact of IV-administered Bendavia on the endothelial dysfunction induced by a single cigarette.
- Trial name
- NCT01518985
- Testing
- Bendavia, Sterile saline (0.9%), Cigarette smoking
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Stealth BioTherapeutics Inc.
Diabetes Mellitus, Type 2
Skin and Retina Microvascular Endothelial Function in Healthy, Insulin Resistant and Type 2 Diabetic Subjects
The purpose of this study is to investigate microvascular endothelial function in the retina of lean, obese, and type 2 diabetic subjects and to compare microvascular endothelial function in the retina with several other…
- Trial name
- NCT01241370
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- ELAB-Logistics
Endothelial Dysfunction
Effect of Phenolic Acids on the Human Vasculature
This study evaluates effects of different doses of phenolic acids on healthy volunteers.
- Trial name
- NCT03599128
- Testing
- 43.3 mg hydrolyzed green coffee extract, 86.6 mg hydrolyzed green coffee extract, 173 mg hydrolyzed green coffee extract
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)