Clinical trials: Endothelial Function (FMD)
Endothelial Progenitor Cells Numbers, Endothelial Function (FMD)
Study Effect of Red Wine Consumption on Endothelial Progenitor Cells and Endothelial Function
Light-to-moderate alcohol consumption has been associated with a reduction of cardiovascular events, and red wine seems to offer more benefits than any other type of alcoholic beverages.
- Trial name
- NCT00755014
- Testing
- red wine
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Hypertension, Hypertrophy, Left Ventricular
Does Allopurinol Reduce Thickening of the Left Ventricle of the Heart in Patient With Treated Hypertension?
The presence of Left ventricular hypertrophy (LVH) confers high cardiovascular risk in hypertensive patients. LVH remains highly prevalent even when blood pressure (BP) is controlled.
- Trial name
- ALLAY (NCT02237339)
- Testing
- Allopurinol
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- University of Dundee
End Stage Heart Failure
Endothelial Function and Circulating Microparticle in Patients Under LVAD Support
The aims of this project are 1) to evaluate whether circulating micraparticals (MPs) in patients with LVAD impair endothelial function and 2) to assess the procoagulative activity of circulating MPs in patients with LVAD in a…
- Trial name
- MP-LVAD (NCT03923413)
- Testing
- Blood samples
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Type 2 Diabetes Mellitus, Coronary Artery Disease
Study Effects of Ginkgo Biloba Extract on Endothelial Cell Function and Genetic Effects on the Response to Ginkgo Biloba Extract in Diabetic Patients With Stable Coronary Artery Disease
Type 2 diabetes is associated with a markedly increased risk for atherosclerotic coronary arteries and cerebrovascular diseases.
- Trial name
- NCT01038050
- Testing
- Ginkgo Biloba Extract (GBE)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
FMD
Effects of Five Days of Physical Inactivity on Endothelial Function in Healthy Humans
Physical inactivity is a significant predictor of major non-communicable diseases such as type 2 diabetes (7%), cardiovascular disease (6%), musculoskeletal disorders and some types of cancer, and has been proposed to be the 4th…
- Trial name
- NCT04199949
- Testing
- Inactivity
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Hyperlipidemia
Endothelial Hyperpolarization in Humans
The purpose of this study is to elucidate the role Endothelium-Derived Hyperpolarizing Factor (EDHF) plays in dilating blood vessels and whether it differs between healthy people and those with high cholesterol.
- Trial name
- NCT00166166
- Testing
- Tetraethylammonium (TEA), L-NG-monomethyl Arginine (L-NMMA), Bradykinin
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Emory University
Borderline High LDL-cholesterol
Effects of Ubiquinol and Ubiquinone on Vascular Function in Healthy Adults With Borderline High LDL-Cholesterol
This randomized, double-blind, placebo-controlled clinical trial will evaluate the effects of Ubiquinol and Ubiquinone on vascular endothelial function in generally healthy adults with borderline high LDL-cholesterol.
- Trial name
- NCT07881601
- Testing
- Ubiquinol, Ubiquinone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Improve Endothelial Function and Decrease Vascular Stenosis
Phosphodiesterase Type 5 Inhibition to Improve Endothelial Function and Vascular Remodeling in Chronic Kidney Disease and End Stage Renal Disease Patients Requiring New Arteriovenous Fistula
Patients with stage IV and V chronic kidney disease and end stage renal disease requiring hemodialysis at University of Alabama at Birmingham (UAB) Dialysis Clinics will be recruited from the UAB Vascular Access Clinic, which has…
- Trial name
- NCT02414204
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Alabama at Birmingham
Heart Failure, Anthracycline-induced Cardiac Toxicity
Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients
The goal of this randomized, double-blind, placebo-controlled clinical trial is to determine whether dapagliflozin, a sodium-glucose cotransporter-2 (SGLT-2) inhibitor, can help prevent anthracycline-induced cardiotoxicity caused…
- Conditions
- Heart Failure, Anthracycline-induced Cardiac Toxicity, Endothelial Function (FMD), Arterial Stiffness
- Trial name
- Alpaca (NCT07245069)
- Testing
- Dapagliflozin 10 mg
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Cardiovascular Diseases
Mediterranean Diet and Endothelial Function
To assess the effect of Mediterranean diet and some of its specific components (olive oil, non fried fish and nuts) on endothelial function in overweight and obese patients
- Trial name
- NCT01797211
- Testing
- Mediterranean diet
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bari
Endothelial Dysfunction, FMD
Role of Oxygen for Vascular Dysfunction
Hypoxemia may contribute increased morbidity and mortality in chronic obstructive pulmonary disease (COPD) patients. We aim to characterize the role of acute and chronic hypoxemia for vascular function.
- Conditions
- Endothelial Dysfunction, FMD, IMT, Microcirculation
- Trial name
- NCT02127333
- Where
- Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie