Clinical trials: Endotracheal Intubation, open to volunteers
Intubation Skill, Intubation Complications
Establish Whether Hyperangulated Videolaryngoscopy (HAVL) Can be Used to Facilitate Tracheal Intubation Effectively and Safely in Unselected Adult Patients; Describe the Population in Whom HAVL Fails to Facilitate Tracheal Intubation Successfully, Identifying Any Contributory Characteristics.
When patients have a general anaesthetic (go to sleep for surgery), the anaesthetist often places a small tube into their windpipe (intubation) to help them breathe.
- Conditions
- Intubation Skill, Intubation Complications, Intubation With Uncuffed Endotracheal Tube
- Trial name
- NCT07600502
- Testing
- Hyperangulated videolaryngoscopy
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Medical Device, Medical Device Performance
Clinical Evaluation of an Airborne Pathogen Containment Device: Randomized Open-label Equivalence Trial During Endotracheal Intubation
The aim of this study is to test a bubble-like dome (made of clear plastic) being placed over patients' heads during surgery as a tool to prevent the spread of germs through the air in hospitals.
- Conditions
- Medical Device, Medical Device Performance, Aerosol Generating Procedure
- Trial name
- NCT06968377
- Testing
- A novel airborne pathogen containment device.
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Acute Respiratory Failure
Tube Size Randomized Trial During Emergency Tracheal Intubation
The BREATHE trial is a parallel-group, pragmatic, randomized clinical trial comparing the effectiveness of smaller versus larger endotracheal tubes for mechanical ventilation of critically ill adults at 7 geographically diverse…
- Trial name
- BREATHE (NCT06939361)
- Testing
- Smaller endotracheal tube, Larger endotracheal tube
- Where
- 7 sites in United States
- Volunteers
- 3,180 people
- Sponsor
- Vanderbilt University Medical Center
Intubation Complication
Comparison of First Attempt Success Based on Endotracheal Tube Type During Videolaryngoscope-guided Intubation Without Stylet
Patients are randomly assigned to either the oral RAE tube group (Group O) or the reinforced tube group (Group R). In both groups, tracheal intubation is performed using a videolaryngoscope without a stylet, and the first-attempt…
- Trial name
- NCT07682480
- Testing
- endotracheal tube
- Volunteers
- 246 people
- Sponsor
- Seoul National University Hospital
Acute Respiratory Failure, Electrical Impedance Tomography (EIT)
Predicting High-Flow Nasal Oxygen Failure Within 72 Hours Using a Physiology-Informed Dual-Domain Model at 30 Minutes
This is a single-center, ambispective observational cohort study of adults with acute hypoxemic respiratory failure (AHRF) receiving high-flow nasal oxygen (HFNO) as initial respiratory support. The study includes three stages.
- Conditions
- Acute Respiratory Failure, Electrical Impedance Tomography (EIT), High-Flow Nasal Oxygen Therapy
- Trial name
- EFI-HFNO (NCT07366541)
- Testing
- High-Flow Nasal Oxygen Therapy, Electrical Impedance Tomography Monitoring
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Ruijin Hospital
Ultrasonography, Airway Management
Evaluation of Anterior Neck Ultrasound in Predicting Difficult Airway in Obese Patients
Obese patients are at increased risk of difficult airway management due to anatomical changes in the anterior neck soft tissues.
- Conditions
- Ultrasonography, Airway Management, Intubation, Intratracheal, Obesity and Overweight
- Trial name
- NCT07346768
- Testing
- None (Observational study)
- Volunteers
- 52 people
- Sponsor
- Gaziantep City Hospital
Delayed Sequence Intubation, Rapid Sequence Induction and Intubation
Comparison of Peri-intubation Oxygenation Values and Complications in Patients Intubated With the Delayed Versus Rapid Sequence Intubation Protocols
This study compares two different methods of helping patients breathe by placing a tube in their airway (intubation) in an emergency setting.
- Conditions
- Delayed Sequence Intubation, Rapid Sequence Induction and Intubation, Intubation, Intubation Complications
- Trial name
- DSI vs RSI (NCT07380763)
- Testing
- Delayed Sequence Intubation, Rapid Sequence Intubation
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Intensive Care Unit ICU, Intubation
The Effects of Endotracheal Suctioning on Pain and Serum Markers
The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients.
- Conditions
- Intensive Care Unit ICU, Intubation, Critical Illness, Mechanical Ventilation
- Trial name
- NCT06692400
- Testing
- endotracheal tube suctioning
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Loma Linda University
Voice Disorder Due to Iatrogenic Factor, Endotracheal Intubation During Surgery
Objective and Perceptual Characteristics of the Voice After Endotracheal Intubation in Head and Neck Surgery
Introduction: Possible consequences of endotracheal intubation are post-intubation voice changes. Hypothesis: Endotracheal intubation during head and neck surgery is associated with objective and perceptual voice disorders.
- Conditions
- Voice Disorder Due to Iatrogenic Factor, Endotracheal Intubation During Surgery, Thyroid Surgery, Head and Neck Surgery
- Trial name
- VOICE (NCT07131800)
- Where
- Croatia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Neuromuscular Blockade
Safety and Efficacy of HRS-9190 Compared to Rocuronium for Tracheal Intubation and Bolus Maintenance in Adults
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium.
- Trial name
- NCT07746726
- Testing
- HRS-9190, Rocuronium
- Where
- 2 sites in China
- Volunteers
- 320 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Airway Management, Fiberoptic Guided Intubation
Patient Experience of Transoral Versus Transnasal Awake Tracheal Intubation
Airway management problems are key drivers for anesthesia-related adverse events. Awake tracheal intubation using flexible bronchoscopy and preserved spontaneous breathing (ATI:FB) is a recommended technique to manage difficult…
- Conditions
- Airway Management, Fiberoptic Guided Intubation, Patient Experience
- Trial name
- NCT06955884
- Where
- Germany
- Volunteers
- 198 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Airway Management, Intubation, Endotracheal
Two Video Laryngoscopes (Laringocel® and C-MAC®) for First-Attempt Intubation in Adults Undergoing Elective Surgery
This study will test two video laryngoscopes that help doctors place a breathing tube during surgery. A breathing tube is needed for people who receive general anesthesia so they can breathe safely.
- Trial name
- LARINGOCOL (NCT07239141)
- Testing
- Laringocel® videolaryngoscope, C-MAC® D-Blade videolaryngoscope
- Where
- Colombia
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Mario Zamudio
Postoperative Sore Throat, Hoarseness
A Randomized, Comparative, Controlled Study of Differences in the Incidence of Postoperative Sore Throat (POST) by Inner Diameter Size of the TaperGuardTM Endotracheal Tube (ETT)
Postoperative sore throat (POST) is a common complication following general anesthesia involving endotracheal intubation, often leading to decreased patient satisfaction.
- Trial name
- NCT07511998
- Testing
- TaperGuard™ Endotracheal Tube
- Where
- South Korea
- Volunteers
- 246 people
- Sponsor
- Kyungpook National University Chilgok Hospital
Endotracheal Intubation
Impact of Via CT-based 3D Printing Technology on Success Rate in Endotracheal Intubation in Students
The objective of this project is to develop a tracheal intubation teaching curriculum covering both normal and difficult airways using CT three-dimensional imaging and 3D printing technologies, enabling trainees to intuitively…
- Trial name
- NCT07612995
- Testing
- the course training-3D, the course training- traditional
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- xiaojing wang
Hemodynamics
The Effect-site Concentration of Remifentanil Blunting Endotracheal Intubation Responses During Anesthesia Induction With Lidocaine or Sufentanil Combined With Etomidate: A Randomized Controlled Study
The aim of this study was to compare the effect-site target concentration (including EC₅₀ and EC₉₀) of remifentanil required to suppress cardiovascular responses to tracheal intubation during anesthesia induction with etomidate…
- Trial name
- NCT07089173
- Testing
- Intravenous normal saline (NS 0.9), intravenous sufentanil, Intravenous lidocaine
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Peking University Shenzhen Hospital
Cardiac Catheterization, Endotracheal Tube
Ultrasound-detectable Endotracheal Tube: a Feasibility Study
The researchers are studying whether special features make it easier to see if the breathing tube is in the correct place. It is hoped that the investigational device will enable more accurate placement (depth and trachea vs.
- Trial name
- NCT05941013
- Testing
- Ultrasound detectable cuffed endotracheal tube (USD-ETT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- John R. Charpie
General Anesthesia Using Endotracheal Intubation
Algorithm Predicting Intraoperative Changes in Cardiac Output Using Capnography
Conventional monitoring of cardiac output requires an invasive procedure and an additional device, which can lead to increased risk and cost.
- Trial name
- NCT07061548
- Testing
- No Intervention: Observational Cohort
- Where
- South Korea
- Volunteers
- 2,005 people
- Sponsor
- Samsung Medical Center
Oral Infection
Prediction Model for Delayed Extubation of Tracheal Intubation in Patients With Maxillofacial Space Infection After Abscess Incision and Drainage Surgery
Retrospective exploration of the risk factors associated with mechanical ventilation and tracheal extubation twenty-four hours after abscess incision and drainage surgery in patients with maxillofacial space infection.
- Trial name
- Prediction mod (NCT06853808)
- Volunteers
- 400 people
- Sponsor
- Henan Provincial People's Hospital
Laryngoscopic Stress Response, Dexmedetomidine
Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial
After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication.
- Conditions
- Laryngoscopic Stress Response, Dexmedetomidine, Lignocaine
- Trial name
- NCT07611890
- Testing
- IV dexmedetomidine, IV Lignocaine
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Rawalpindi Institute of Cardiology
Airway Management
First Attempt Success in Tracheal Intubation Through Supraglottic Airway Devices Without Fiberoptic Guidance
This randomized controlled trial aims to compare the first-attempt success rate of tracheal intubation through supraglottic airway devices using a conventional intubating supraglottic airway device versus a video-assisted…
- Trial name
- NCT07704723
- Testing
- Video-assisted supraglottic airway device, Conventional intubating supraglottic airway device
- Volunteers
- 204 people
- Sponsor
- Seoul National University Hospital