Clinical trials: Endovascular Treatment
Ischemic Stroke, Occlusion, Cerebrovascular
Revive AIS Patients ImmeDiately
This is a multicenter, prospective registry clinical study to evaluate the real-world efficacy and safety of intra-arterial treatment for acute ischemic stroke using Revive SE device on the basis of standardised medical treatment.
- Trial name
- RAPID (NCT03007082)
- Testing
- Revive SE intracranial thrombectomy device
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Changhai Hospital
Ischemic Stroke
Head dOwn Position Before Endovascular Treatment for Large veSsel Occlusion (HOPES5)
Recent studies suggest that head-down positioning (HDP) intervention may improve outcomes in ischemic stroke. In the era of reperfusion therapy, a key protective strategy is to administer neuroprotective interventions before…
- Trial name
- NCT07172789
- Testing
- head down position
- Where
- China
- Volunteers
- 210 people
- Sponsor
- General Hospital of Shenyang Military Region
Acute Ischemic Stroke
Safety and Tolerability of Adjunctive TBO-309 in Reperfusion for Stroke
STARS is a prospective, multicentre, open-label, dose escalation, Phase IIa study to assess the safety and tolerability of TBO-309, an adjuvant antiplatelet therapy, in patients with AIS.
- Trial name
- STARS (NCT05363397)
- Testing
- TBO-309
- Where
- 7 sites in Australia
- Volunteers
- 80 people
- Sponsor
- The Florey Institute of Neuroscience and Mental Health
Aneurysms
A Study to Look at Performance of MICRUSFRAME and GALAXY Coils for the Treatment of Intracranial Aneurysms
A post-market registry evaluating ruptured/unruptured aneurysms treated with MICRUSFRAME and GALAXY coils
- Trial name
- STERLING (NCT03642639)
- Testing
- MICRUSFRAME and GALAXY coils
- Where
- 51 sites in United States, Belgium and 8 more
- Volunteers
- 723 people
- Sponsor
- Cerenovus, Part of DePuy Synthes Products, Inc.
Acute Stroke
Intra-arterial Magnesium Administration for Acute Stroke
Stroke is the second leading cause of death and the leading cause of adult disability worldwide. This investigation will address the safety and feasibility of directed, intra-arterial Magnesium measurement and therapy, through…
- Trial name
- NCT01502761
- Testing
- Magnesium Sulfate
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- University of Southern California
Acute Ischemic Stroke
Acute Ischemic Stroke Registry for Endovascular Treatment
The Acute Ischemic Stroke Registry for Endovascular Treatment (AIS-EVT) is an academic, prospective, multicenter, observational registry study.
- Trial name
- NCT05213754
- Testing
- Endovascular Treatment
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Capital Medical University
Aortic Aneurysm, Abdominal, Endovascular
Comparison of Surveillance Versus Aortic Endografting for Small Aneurysm Repair
Objective of the present study is to compare endovascular repair versus surveillance and, eventually delay treatment in patients with small abdominal aortic aneurysms (AAA), with respect to patient survival, AAA rupture and AAA…
- Trial name
- CAESAR (NCT00118573)
- Testing
- EVAR (Endovascular repair of Abdominal Aortic aneurysm), Surveillance
- Where
- 20 sites in Czechia, France and 7 more
- Volunteers
- 360 people
- Sponsor
- University Of Perugia
Acute Ischemic Stroke Due to Medium-vessel-occlusion
IAT-MeVO Trial Domain Within the ACT-GLOBAL Adaptive Platform Trial
IAT-MeVO is an international, multicenter, prospective, randomised, open-label, blinded end-point assessed (PROBE) trial, to evaluate the efficacy and safety of endovascular therapy (EVT) [intra-arterial thrombolysis (IAT)-based]…
- Trial name
- IAT-MeVO (NCT07336927)
- Testing
- Endovascular Treatment
- Where
- China
- Volunteers
- 614 people
- Sponsor
- Bo Wu
Aortic Dissection
Hemodynamic Changes in the Aorta After Endovascular Treatment of the Aortic Dissection
Aortic dissection (AD) is a serious pathology affecting one person for 300 000 habitants per year. In case of complicated AD on the descending aorta, it is necessary to perform an endovascular surgery in association with medical…
- Trial name
- 4DAo (NCT03669055)
- Testing
- Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hospices Civils de Lyon
Acute Ischemic Stroke, Large Vessel Occlusion
Sevoflurane vs. Propofol for General Anesthesia in Patients With Acute Ischemic Stroke Treated With Endovascular Therapy
Acute ischemic stroke occurs when a blood clot blocks blood flow to part of the brain. Patients with this condition may require endovascular therapy, a procedure used to remove the clot and restore blood flow.
- Trial name
- SAVE (NCT07902791)
- Testing
- Sevoflurane, propofol (drug)
- Where
- Spain
- Volunteers
- 314 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Stroke, Acute Ischemic, Albumin
Intra-arterial Albumin Infusion After Endovascular Therapy for Stroke Patients
The purpose of this study is to investigate the safety and feasibility of intra-arterial albumin infusion for patients with acute ischemic stroke after successful thrombectomy and to further explore the optimal dose of albumin…
- Conditions
- Stroke, Acute Ischemic, Albumin, Endovascular Procedures, Large Vessel Occlusion
- Trial name
- NCT05953623
- Testing
- Albumin
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Tianjin Huanhu Hospital
Artery Injury
Open and Endovascular Surgical Treatment for Artery Injuries
Traumatic injuries of peripheral arteries are often associated with multiple injuries, massive hemorrhage, state of shock, and loss of blood supply, as well as with high mortality.
- Trial name
- NCT03872323
- Testing
- Endovascular treatment, Open surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jinan Military General Hospital
Brain Stroke, Stenting Treatment
Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis
The study objective is to establish the safety and efficacy of endovascular adjunct stenting for patients undergoing mechanical thrombectomy (MT) that are found to have residual stenosis (70-99%) following attempted clot…
- Conditions
- Brain Stroke, Stenting Treatment, Acute Ischemic Stroke
- Trial name
- EVEREST (NCT07356284)
- Testing
- Mechanical Thrombectomy plus adjunct stenting, Mechanical Thrombectomy
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- ProMedica Health System
Aortic Aneurysm, Abdominal
Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck
The HERCULES trial is a Randomized controlled clinical trial designed to prospectively compare endosuture aneurysm repair (ESAR) to standard endovascular aneurysm repair (EVAR) clinical outcomes in treatment of infrarenal…
- Trial name
- HERCULES (NCT05484115)
- Testing
- endovascular aneurysm repair (EVAR) using the Endurant II/IIs stent graft system, endosuture aneurysm repair (ESAR) using Heli-FX EndoAnchor system
- Where
- 36 sites in United States, France and 6 more
- Volunteers
- 300 people
- Sponsor
- Rijnstate Hospital
Aortic Aneurysm, Abdominal, Complication of Surgical Procedure
Myocardial Injury in Treatment of AAA
Comparison of elective infrarenal aneurysm surgery with open and endovascular technique, respectively, for subclinical ischemic myocardial injury detectable with troponin T and/or 3-channel Holter ECG with ST analysis
- Conditions
- Aortic Aneurysm, Abdominal, Complication of Surgical Procedure, Myocardium; Ischemic
- Trial name
- TREATROP (NCT04292652)
- Testing
- AAA surgery
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Acute Ischemic Stroke
Endovascular Therapy Combined With Tirofiban for Intracranial Atherosclerotic Acute Ischemic Stroke
This randomized controlled trial aims to evaluate whether adjunctive tirofiban therapy combined with endovascular treatment (EVT) improves neurological outcomes in patients with acute large vessel occlusion due to large-artery…
- Trial name
- ANGEL-DRUG (NCT07026318)
- Testing
- Tirofiban
- Where
- China
- Volunteers
- 716 people
- Sponsor
- Beijing Anzhen Hospital
Iliofemoral Vein Stenosis, Iliofemoral Vein Occlusion
Vflower Stent System for Iliofemoral Vein Stenosis and Occlusion: A Multicenter Real-World Study
This multi-center, real-world observational study is being conducted at five hospitals in China to evaluate the effectiveness of the Vflower venous stent system in patients with iliofemoral vein stenosis or occlusion.
- Trial name
- V-STAR (NCT07809204)
- Testing
- Vflower venous stent system (self-expanding nitinol stent for iliofemoral venous lesions)
- Volunteers
- 310 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Endovascular Treatment, Chronic Subdural Hematoma
Middle Meningeal Artery Embolization for Patients With Chronic Subdural Hematoma
COMPLEMENT study (ChrOnic subdural hematoMa Patients suppLemented with Embolization of Middle mENingeal artery Trial) is a prospective, open label, blinded endpoint (PROBE), Japanese, two-arm, randomized, controlled, post-market…
- Trial name
- NCT06772740
- Testing
- Middle meningeal artery embolization
- Where
- Japan
- Volunteers
- 600 people
- Sponsor
- Kazutaka Uchida
Pelvic Congestive Syndrome, Pelvic Varices
Endovascular Versus Medical Treatment for the Pelvic Congestion Syndrome
Compare the efficacy and safety of endovascular treatment with sandwich technique (controlled release coils and 2% polidocanol foam) associated with diosmin-hisperidine and ibuprofen medical treatment and only the best chronic…
- Conditions
- Pelvic Congestive Syndrome, Pelvic Varices, Venous Disease
- Trial name
- ENDPCS (NCT04358497)
- Testing
- Medtronic® Concerto® detachable coil system, sclerosis, Diosmin / Hesperidin
- Volunteers
- 120 people
- Sponsor
- Hospital de Clínicas Dr. Manuel Quintela
Stroke
MR-based Collateral Imaging to Predict Response to Endovascular Treatment of Stroke (FAST-COLL Study)
Based on the results of recent randomized controlled trials, current international guidelines recommend the initiation of endovascular treatment within 6 hours of symptom onset for acute ischemic stroke.
- Trial name
- NCT02668627
- Testing
- Endovascular treatment
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Samsung Medical Center