Clinical trials: Endovascular Treatment
Technical Sucess, Freedom From Type I and III Endoleaks at 12 Months
Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms
Patients who are found to have an aneurysm (bulge) in the abdominal aorta, which is the blood vessel in your abdomen (belly) that supplies blood to most of your lower body, including major organs and your legs.
- Conditions
- Technical Sucess, Freedom From Type I and III Endoleaks at 12 Months, Freedom From Stent Graft Migration at 12 Months, Freedom From Aortic Aneurysm Enlargement at 12 Months
- Trial name
- NCT07019454
- Testing
- Physician Modified Endografting
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Baystate Medical Center
Submassive Pulmonary Embolism
Long Term Effects of Treating Submassive Pulmonary Embolism With Ultra-sound Accelerated Thrombolysis
Patients with Submassive Pulmonary Embolism treated with ultra-sound therapy will have an improved right ventricular function 72 hours post treatment.
- Trial name
- SPEAR (NCT01899339)
- Testing
- submassive PA treatment with Ekosonic endo device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Corewell Health West
Intracranial Aneurysm
Safety and Efficacy of the LVIS and LVIS JR Devices in the Endovascular Treatment of Intracranial Aneurysms
A French, multicenter, prospective, observational, "real life" assessment of the safety and efficacy of LVIS and LVIS JR devices in the treatment of intracranial aneurysms
- Trial name
- NCT03553771
- Testing
- LVIS and LVIS JR
- Where
- 20 sites in France
- Volunteers
- 130 people
- Sponsor
- Microvention-Terumo, Inc.
Basilar Artery Occlusion, Ischemic Stroke
Basilar Artery Occlusion Chinese Endovascular Trial
Endovascular treatment of acute ischemic stroke has shown strong benefit in several prospective randomized trials in the anterior circulation and endovascular therapy for basilar artery occlusion has shown promising results in…
- Conditions
- Basilar Artery Occlusion, Ischemic Stroke, Cerebrovascular Disorders
- Trial name
- NCT02737189
- Testing
- Mechanical embolectomy, Medical Treatment
- Where
- 36 sites in China
- Volunteers
- 217 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke Patients, Acute Ischemic Stroke
Guiding Catheters in Endovascular Stroke Therapy - Are Balloon Guided Catheters Superior?
The BEST study is an academically initiated, single-center, prospective, randomized controlled clinical trial investigating the potential advantages and disadvantages of using a guide catheter with or without a balloon in the…
- Conditions
- Acute Ischemic Stroke Patients, Acute Ischemic Stroke, Acute Ischemic Stroke AIS
- Trial name
- BEST (NCT07478042)
- Testing
- Ballon guide catheter, Guide catheter without balloon
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- University Hospital Heidelberg
Acute Ischemic Stroke, Anterior Circulation Brain Infarction
Remote Ischemic Conditioning for Acute Ischemic Stroke Treated With Mechanical Thrombectomy（RECAST-MT）
For patients with acute ischemic stroke caused by large vessel occlusion, endovascular thrombectomy has been demonstrated to be the most effective therapy, as approximately 90% of the occluded vessels can be recanalized.
- Trial name
- RECAST-MT (NCT06559241)
- Testing
- 14-day remote ischemic conditioning, 30-day remote ischemic conditioning, Endovascular thrombectomy
- Where
- 56 sites in China
- Volunteers
- 2,105 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke Due to Medium-vessel-occlusion
IAT-MeVO Trial Domain Within the ACT-GLOBAL Adaptive Platform Trial
IAT-MeVO is an international, multicenter, prospective, randomised, open-label, blinded end-point assessed (PROBE) trial, to evaluate the efficacy and safety of endovascular therapy (EVT) [intra-arterial thrombolysis (IAT)-based]…
- Trial name
- IAT-MeVO (NCT07336927)
- Testing
- Endovascular Treatment
- Where
- China
- Volunteers
- 614 people
- Sponsor
- Bo Wu
Vascular Closure, Endovascular Procedure
Safety and Efficacy of the Vascular Closure Device (Tonbridge) in Hemostasis Treatment of Femoral Artery Puncture
The purpose of this study is to verify the safety and efficacy of the Vascular Closure Device (Tonbridge) in hemostasis treatment for femoral artery puncture.
- Conditions
- Vascular Closure, Endovascular Procedure, Hemostasis, Femoral Artery
- Trial name
- NCT05822804
- Testing
- Vascular Closure Device (Tonbridge), EXOSEAL Vascular Closure Device (Codis Corporation)
- Where
- 7 sites in China
- Volunteers
- 228 people
- Sponsor
- Ton-Bridge Medical Tech. Co., Ltd
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Stroke, Acute
Evaluation of Direct Transfer to Angiography Suite vs. Computed Tomography Suite in Endovascular Treatment: Randomized Clinical Trial (ANGIOCAT)
To evaluate the hypothesis that an ultra-fast triage with one-stop in angiography suite based on cone-beam CT compared to traditional protocol offers a better outcome in the distribution of the modified Rankin Scale scores at 90…
- Trial name
- ANGIOCAT (NCT04001738)
- Testing
- Direct Transfer to Angio Suite
- Where
- Spain
- Volunteers
- 174 people
- Sponsor
- Hospital Vall d'Hebron
Aneurysm, Aneurysm, Intracranial
Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)
The objective of the Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms with Surpass Elite with GUARDian Flow Diverter (GUARD) trial is to evaluate the safety and efficacy of the Surpass Elite with Guardian…
- Trial name
- GUARD (NCT06872684)
- Testing
- Surpass Elite with Guardian Flow Diverter System
- Where
- 20 sites in United States
- Volunteers
- 183 people
- Sponsor
- Stryker Neurovascular
Ischemic Stroke
Sedation Versus General Anesthesia for Endovascular Therapy in Acute Stroke - Impact on Neurological Outcome
The purpose of this study is to evaluate whether general anesthesia or sedation technique is preferable during embolectomy for stroke, measured in terms of three months neurological impairment.
- Trial name
- ANSTROKE (NCT01872884)
- Testing
- Sevorane Remifentanil, Remifentanil
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Sahlgrenska University Hospital
Intracranial Aneurysm
Hemodynamic Analysis for Intracranial Aneurysms Recanalization After Endovascular Treatment
This study was designed to collect a large series of patients with aneurysms treated endovascularly to analyze hemodynamic factors that affect aneurysm recanalization.
- Trial name
- HARET (NCT02812108)
- Testing
- intracranial stent, flow diverter and coils
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Neurosurgical Institute
Pelvic Congestive Syndrome, Pelvic Varices
Endovascular Versus Medical Treatment for the Pelvic Congestion Syndrome
Compare the efficacy and safety of endovascular treatment with sandwich technique (controlled release coils and 2% polidocanol foam) associated with diosmin-hisperidine and ibuprofen medical treatment and only the best chronic…
- Conditions
- Pelvic Congestive Syndrome, Pelvic Varices, Venous Disease
- Trial name
- ENDPCS (NCT04358497)
- Testing
- Medtronic® Concerto® detachable coil system, sclerosis, Diosmin / Hesperidin
- Volunteers
- 120 people
- Sponsor
- Hospital de Clínicas Dr. Manuel Quintela
Peripheral Arterial Disease
Safety and Effectiveness of Jetstream Atherectomy System (J-SUPREME)
The purpose of this study is to evaluate the safety and effectiveness of the Jetstream Atherectomy System for the treatment of Japanese patients with symptomatic occlusive atherosclerotic lesions in native superficial femoral…
- Trial name
- NCT02733653
- Testing
- Jetstream Atherectomy System
- Where
- 10 sites in Japan
- Volunteers
- 60 people
- Sponsor
- Boston Scientific Corporation
Heart Failure
Endovascular NeuromoDulation Treatment fOr Heart Failure Patients (ENDO-HF)
The purpose of the ENDO-HF study is to determine the safety \& performance of the Harmony System for the treatment of heart failure
- Trial name
- NCT02633644
- Testing
- Harmony System
- Where
- 5 sites in Belgium, Croatia and 2 more
- Volunteers
- 30 people
- Sponsor
- Enopace Biomedical
Acute Ischemic Stroke
Infarct Growth After Intravenous Tocilizumab in Adults With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy - ILLUMINATE
The goal of this phase II, placebo-controlled intervention study is to investigate whether tocilizumab, an interleukin-6 (IL-6) receptor inhibitor, may have a neuroprotective effect by reducing infarct growth in adults with acute…
- Trial name
- Illuminate (NCT07870681)
- Testing
- Tociliuzumab
- Where
- 6 sites in Denmark, Norway
- Volunteers
- 156 people
- Sponsor
- Oslo University Hospital
Renal Artery Stenosis
Renal Perfusion Assessment in the Endovascular Treatment of Renal Artery Stenosis
The clinical benefits of endovascular treatment in renal artery stenosis remain controversial. This study uses arterial spin labelling MRI and flat-panel detector parenchymal blood volume imaging to observe the change in renal…
- Trial name
- NCT05603221
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Thoracoabdominal Aortic Aneurysm
"Percutaneous Axillary Access in the Endovascular Treatment of Thoracoabdominal Aortic Pathology" (PAXA)
Since the development of custom-made fenestrated and branched endografts a novel therapeutic option for the management of thoracoabdominal and para-renal aortic aneurysms was made accessible.
- Trial name
- PAXA (NCT03223311)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Stroke, Acute, Vessels; Occlusion
Blood Pressure Management in Stroke Following Endovascular Treatment
The aim of DETECT is to prove the feasibility of a multicenter phase III trial testing the hypothesis that intensive blood pressure control immediately after successful endovascular stroke thrombectomy can improve patient…
- Conditions
- Stroke, Acute, Vessels; Occlusion, Blood Pressure, Endovascular Thrombectomy
- Trial name
- DETECT (NCT04484350)
- Testing
- Labetalol, Hydralazine, Enalapril
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Hamilton Health Sciences Corporation