Clinical trials: Endovascular Treatment
Stroke, Ischemic
Endovascular treatmenT for Acute Ischemic Stroke in China (DETECT2-China)
This is a prospective real world registry study, aiming to explore the effectiveness and safety of endovascular treatment of acute ischemic stroke in a Chinese population.
- Trial name
- NCT05092139
- Testing
- endovascular treatment
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- General Hospital of Shenyang Military Region
PAD
Endovascular Denervation for the Treatment of Patients With Peripheral Arterial Disease
Sympathetic overactivity partly promotes the development of peripheral artery disease which mainly leads to ischemia of the lower limbs.
- Trial name
- EDPAD (NCT05345431)
- Testing
- endovascular denervation, PTA
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Zhongda Hospital
Middle Cerebral Artery Aneurysm
Prospective, Multicenter Cohort Study on the Safety and Efficacy of Treatment for Middle Cerebral Artery Aneurysms
Intracranial aneurysm is one of the most common cerebrovascular diseases, with a prevalence of about 3.2%. With the aging of the population and the further popularization of MRA and other examination methods, the prevalence of…
- Trial name
- NCT04927520
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Acute, Stroke, Ischemic
Carotid Artery Stenting During Endovascular Treatment of Acute Stroke
Rationale: Approximately 20% of the patients with acute ischemic stroke due to an intracranial large vessel occlusion (LVO) has a high-grade stenosis in the ipsilateral cervical carotid artery.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Carotid Stenosis, Carotid Atherosclerosis
- Trial name
- CASES (NCT06511089)
- Testing
- carotid artery stenting during EVT, no carotid artery stenting during EVT
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- University Medical Center Groningen
Ischemic Stroke, Arterial Occlusion
Multimodal Neuroimaging in the Selection of Acute Ischemic Stroke (AIS) Patients to Endovascular Treatment (EVT)
To study the feasibility and usefulness of multimodal MR compared to multimodal CT to select patients with acute ischemic stroke and favorable clinical outcome after mechanical thrombectomy.
- Conditions
- Ischemic Stroke, Arterial Occlusion, CTS, Magnetic Resonance Imaging
- Trial name
- IMAGECAT (NCT03745391)
- Testing
- MULTIMODAL MAGNETIC RESONANCE (Multimodal MR), MULTIMODAL COMPUTERIZED TOMOGRAPHY (Multimodal CT)
- Where
- Spain
- Volunteers
- 323 people
- Sponsor
- Germans Trias i Pujol Hospital
Abdominal Aortic Aneurysm
Korean Registry of Percutaneous EVAR With INCRAFT Stent Graft for the Treatment of Abdominalaortic Aneurysm (K-INCRAFT)
The sudy purpose is to investigate efficacy and safety of percutaneous endovascular aortic aneurysm repair using INCRAFT stent graft for Korean patients with abdominal aortic aneurysm.
- Trial name
- NCT03952780
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Aneurysm Cerebral
Interest of a Simulated Procedure Performed on a Printed Model in the Endovascular Treatment of Carotid-sylvian Aneurysms
It is now considered that 1% to 2% of the French population has an intracranial aneurysm. The major risk of this malformation is essentially the rupture which will lead in 10% of cases to death immediately, in 30% to 50% death…
- Trial name
- Anev3D (NCT05419661)
- Testing
- Operational Pre-Planning
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Acute Ischemic Stroke
Evaluate Endovascular Treatment of Large Ischemic Stroke With Substantial Penumbra.
Large cerebral infarctions are frequent and associated with a poor outcome. Previous cohort studies results suggest that patients with an acute ischemic stroke with large core and substantial penumbra on perfusion imaging benefit…
- Trial name
- FrameLP (NCT05539404)
- Testing
- Endovascular treatment in addition of best medical treatment.
- Where
- 9 sites in France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Toulouse
Abdominal Aortic Aneurysms (AAA), Endovascular Aneurysm Repair (EVAR)
Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair
This study was a target trial emulation using the National Health Claims database established by the Korean National Health Insurance Service (K-NHIS). 8,325 patients were included.
- Trial name
- EVAR_DAPT_SAPT (NCT06876727)
- Volunteers
- 8,325 people
- Sponsor
- Samsung Medical Center
Intracranial Aneurysm
International Post Market Surveillance Study of Intracranial Aneurysms Treated With an Endovascular Approach
IMPACT is an observational, post market study designed to provide an ongoing safety and performance evaluation of Stryker Neurovascular devices used for the treatment of intracranial aneurysms with an endovascular approach.
- Trial name
- IMPACT (NCT04572230)
- Testing
- Endovascular treatment of intracranial aneurysms using a flow-diverting stent
- Where
- 32 sites in Austria, Finland and 5 more
- Volunteers
- 405 people
- Sponsor
- Stryker Neurovascular
Focal Segmental Glomerulosclerosis, Chronic Kidney Diseases
Stem Cell Therapy for Patients With Focal Segmental Glomerulosclerosis
The purpose of this study is to analyze the safety, renal function, metabolic disorders and quality of life data in patients with focal segmental glomerulosclerosis treated with endovascular infusion of bone marrow derived…
- Trial name
- STEFOG (NCT02693366)
- Testing
- Bone marrow stem cell
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Deep Vein Thrombosis
Safety and Efficacy Study of OmniWave Endovascular System to Treat Deep Vein Thrombosis
This is a prospective, multi-center single arm registry to assess the use of the OmniWave Endovascular System in subjects presenting with either lower or upper extremity acute (symptoms have been present for greater than or equal…
- Trial name
- SONIC I (NCT00640731)
- Testing
- OmniWave Endovascular System
- Volunteers
- 50 people
- Sponsor
- OmniSonics Medical Technologies, Inc.
Stroke, Acute, Neuroprotection
Normobaric Hyperoxia With Extended-Window Endovascular Therapy for Acute Ischemic Stroke (OPENS-EXTEND)
Although endovascular therapy (EVT) has substantially improved recanalization rates and extended the treatment window for acute ischemic stroke, fewer than half of patients achieve functional independence despite successful…
- Conditions
- Stroke, Acute, Neuroprotection, Normobaric Hyperoxia, Endovascular Treatment
- Trial name
- NCT07717216
- Testing
- Oxygen (Normobaric Hyperoxia), Endovascular Therapy
- Volunteers
- 314 people
- Sponsor
- Weifang Medical University
Acute Ischemic Stroke
Randomized Study of Bailout Intracranial Angioplasty Following Thrombectomy for Acute Large Vessel Occlusion
Unfavorable outcomes were associated with failed thrombectomy of acute large vessel occlusions (LVO). The failed thrombectomy rate was 12-41% reported in multiple randomized controlled trials (RCT).
- Trial name
- ANGEL-REBOOT (NCT05122286)
- Testing
- Bailout angioplasty, Standard therapy
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Beijing Tiantan Hospital
Endovascular Therapy, Acute Ischaemic Stroke
Stratified Blood Pressure Management After Endovascular Treatment for Acute Ischemic Stroke
The RESCUE-BP is a multi-centered, prospective, randomized, open label, blinded endpoint (PROBE) phase III trial. In patients with acute ischemic stroke who have undergone endovascular treatment and achieved successful…
- Conditions
- Endovascular Therapy, Acute Ischaemic Stroke, Collateral Circulation, Blood Pressure Management
- Trial name
- RESCUE-BP (NCT07527013)
- Testing
- Stratified Blood Pressure Management
- Where
- China
- Volunteers
- 544 people
- Sponsor
- Beijing Tiantan Hospital
Acute Ischemic Stroke
IDEAL Blood Pressure Management During Endovascular Therapy for Acute Ischemic Stroke
The ideal blood pressure management strategy during endovascular therapy (EVT) for acute ischemic stroke has not been defined. The aim of this pilot randomized clinical trial is to determine whether randomization to a standard…
- Trial name
- IDEAL (NCT04749251)
- Testing
- Individualized blood pressure management, Standard blood pressure management
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Cerebral AV Malformation
PHIL Evaluation in the Endovascular Treatment of Intracranial Cerebral ArterioVenous Malformation (cAVM)
The primary objective of this study is to assess the efficacy and safety of PHIL® liquid embolic agent in endovascular embolization of cerebral arteriovenous malformations.
- Trial name
- NCT03341039
- Where
- 16 sites in Denmark, France and 3 more
- Volunteers
- 20 people
- Sponsor
- Microvention-Terumo, Inc.
Acute Ischaemic Stroke
Efficacy and Security of an Endovascular Treatment as First Choice Procedure Compared With a Standard Intravenous Thrombolytic Therapy Treatment for Patients With Acute Ischemic Stroke Within 4.5 Hours After Onset
This study will compare two ways of treatment for acute ischemic stroke: an endovascular treatment (EVT), defined as intraarterial thrombolysis and/or mechanical thrombectomy as a first choice treatment versus intravenous…
- Trial name
- FUN-TPA (NCT02164357)
- Testing
- EVT (endovascular treatment ), IVT (intravenous thrombolytic therapy)
- Where
- 5 sites in Spain
- Volunteers
- 124 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Stroke, Ischemic, Intravascular Thrombosis
Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With Endovascular Therapy (INSIST-ET)
To explore the safety and feasibility of intra-arterial neuroprotective strategy in acute ischemic stroke patients who received recanalization operation.
- Conditions
- Stroke, Ischemic, Intravascular Thrombosis, Mechanical Thrombectomy
- Trial name
- NCT04664933
- Testing
- Intra-arterial administration of neuroprotective agents
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hui-Sheng Chen
Basilar Artery Occlusion, Ischemic Stroke
Basilar Artery Occlusion Chinese Endovascular Trial in Patients With Large Core Infarct
This study evaluates the safety and efficacy of endovascular therapy for acute basilar artery occlusion with large core infarcts in a multicenter randomized trial.
- Conditions
- Basilar Artery Occlusion, Ischemic Stroke, Large Core Infarct
- Trial name
- BAOCHE3 (NCT07046299)
- Testing
- Endovascular Therapy Plus Best Medical Treatment, Best Medical Treatment Alone
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Capital Medical University