Clinical trials: Endovascular Treatment
Stroke, Intracranial Atherosclerotic Stenosis
SeQuent ® Please CIS for the Treatment of INtracranial Atherosclerotic Stenosis
This study is aiming to evaluate the safety and efficacy of SeQuent® Please CIS in the endovascular treatment of symptomatic intracranial atherosclerotic stenosis and restenosis after interventional therapy.
- Trial name
- SPINAS (NCT06047964)
- Testing
- DCB, POBA
- Where
- 9 sites in China
- Volunteers
- 281 people
- Sponsor
- B. Braun Medical International Trading Company Ltd.
Pulmonary Embolism
tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden
To demonstrate the efficacy and safety of the Bashir™ Endovascular Catheter for the administration of pharmaco-mechanical catheter directed therapy using low dose r-tPA for the treatment of acute submassive pulmonary embolism.
- Trial name
- RESCUE (NCT04248868)
- Testing
- The Bashir™ Endovascular Catheter, r-tPA
- Where
- 19 sites in United States
- Volunteers
- 109 people
- Sponsor
- Thrombolex, Inc.
Endovascular Infection, Bone and Joint Infection
Comparing Oral Versus Parenteral Antimicrobial Therapy
This is an investigator initiated multisite pragmatic randomized controlled trial designed to demonstrate equivalent effectiveness with improved safety of early transition from intravenous (IV) antimicrobial therapy to complex…
- Conditions
- Endovascular Infection, Bone and Joint Infection, Skin and Soft Tissue Infection, Pulmonary Infection
- Trial name
- COPAT (NCT05977868)
- Testing
- Amoxicillin, amoxicillin-clavulanate, cefadroxil, cefpodoxime, cefalexin, ciprofloxacin, delafloxacin, doxycycline, levofloxacin, linezolid, Ampicillin, ampicillin-sulbactam, cefazolin, cefepime, ceftaroline, ceftazidime, ceftazidime-avibactam, dalbavancin, daptomycin, ertapenem
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- West Virginia University
Abdominal Aortic Aneurysm
Evaluation of the Long Term Efficacy of Endovascular Treatment of Type 2 Endoleaks
Endovascular treatment has become the first choice to repair abdominal aortic aneurym, but exposes patients to a risk of endoleaks.
- Trial name
- NCT04409717
- Testing
- Type II endoleak treatment
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Unruptured Intracranial Aneurysm, Flow Diverter
Tirofiban for Reduction of Thromboembolic Events in Endovascular Unruptured Aneurysm Repair
To explore whether administering tirofiban in stent-assisted coiling/flow diverting treatments for participants with unruptured intracranial aneurysms can reduce new ischemic lesions on postoperative DWI sequences compared to…
- Conditions
- Unruptured Intracranial Aneurysm, Flow Diverter, Stent-assisted Coiling, Thromboembolic Events
- Trial name
- TEAR (NCT06238115)
- Testing
- Tirofiban, aspirin, clopidogrel
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Beijing Tiantan Hospital
Aortic Arch, Aortic Diseases
CILCA Arch Registry: Management and Outcomes of Open and Endovascular Repair
This registry aims to provide insights on the pathogenic mechanisms that expose subjects with CILCA arch to the increased risk of postoperative complications.
- Conditions
- Aortic Arch, Aortic Diseases, Bovine Arch
- Trial name
- NCT04995640
- Testing
- open cardiovascular repair or endovascular treatment (TEVAR)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Ospedale San Donato
Aortic Dissection
Zenith® Dissection Clinical Trial
The Zenith® Dissection Clinical Trial is a clinical trial approved by US FDA to study the safety and effectiveness of the Zenith® Dissection Endovascular System in the treatment of acute, complicate Type B aortic dissection.
- Trial name
- NCT01568320
- Testing
- Endovascular Treatment (Zenith)
- Where
- 24 sites in United States, Japan
- Volunteers
- 73 people
- Sponsor
- Cook Research Incorporated
Intracranial Aneurysm
International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)
This multicenter retrospective cohort study aims to evaluate and compare the technical performance, safety, and clinical outcomes of intracranial aneurysms treated with flow diverter stents and endosaccular flow disruptors.
- Trial name
- IRF (NCT06174727)
- Where
- 13 sites in United States, Canada
- Volunteers
- 5,000 people
- Sponsor
- Montefiore Medical Center
BEHAVIOR CHANGE-BASED PHYSICAL ACTIVITY INTERVENTION IN PAD PATIENTS AFTER ENDOVASCULAR REVASCULARIZATION
BEHAVIOR CHANGE INTERVENTION AFTER ENDOVASCULAR REVASCULARIZATION IN PAD
The study titled "Investigation of the Effect of a Behavior Change-Based Physical Activity Program in Patients with Peripheral Artery Disease Who Have Undergone Endovascular Revascularization" will be conducted by Specialist…
- Trial name
- NCT07328646
- Testing
- Behavior Change-Based Physical Activity Program, Supervised Exercise Program, Combined Behavior Change and Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Muğla Sıtkı Koçman University
Aortic Diseases
Percutaneous Endovascular Arch Repair Trial (PEART) Study
This study is the feasible study on a new technique of ZIPPER aortic arch stentgraft system
- Trial name
- NCT05872282
- Testing
- ZIPPER aortic arch stentgraft system
- Where
- 3 sites in China
- Volunteers
- 24 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Peripheral Artery Disease (PAD)
A Study to Evaluate the Safety and Effectiveness of the FastWave Artero™ Peripheral Intravascular Lithotripsy (IVL) System in Adults With Peripheral Artery Disease (PAD)
The purpose of this clinical study is to learn if the FastWave Artero™ Peripheral Intravascular Lithotripsy (IVL) System is safe and works well to help people with peripheral artery disease (PAD) who have hard, calcium-filled…
- Trial name
- SPARC (NCT07209085)
- Testing
- FastWave Artero™ Peripheral IVL System
- Volunteers
- 110 people
- Sponsor
- FastWave Medical
Aortic Aneurysm, Thoracoabdominal
Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA
The primary clinical objective of this study is to evaluate the safety and effectiveness of a physician-modified, fenestrated and branched aortic endoprosthesis for the treatment of thoracoabdominal aortic aneurysms (TAAAs).
- Trial name
- NCT02989948
- Testing
- Physician-modified aortic endograft
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Ischemic Stroke
Safety and Optimal Neuroprotection of neu2000 in Ischemic Stroke With Endovascular reCanalizion (SONIC)
Efficacy and safety of Neu2000, a multi-target drug designed to prevent both NMDA receptor-mediated excitotoxicity and free radical toxicity, will be investigated in acute ischemic stroke patients receiving endovascular treatment…
- Trial name
- SONIC (NCT02831088)
- Testing
- Neu2000KWL High-does group, Neu2000KWL Low-does group
- Where
- 6 sites in South Korea
- Volunteers
- 210 people
- Sponsor
- GNT Pharma
Aortic Aneurysm, Abdominal
Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck
The HERCULES trial is a Randomized controlled clinical trial designed to prospectively compare endosuture aneurysm repair (ESAR) to standard endovascular aneurysm repair (EVAR) clinical outcomes in treatment of infrarenal…
- Trial name
- HERCULES (NCT05484115)
- Testing
- endovascular aneurysm repair (EVAR) using the Endurant II/IIs stent graft system, endosuture aneurysm repair (ESAR) using Heli-FX EndoAnchor system
- Where
- 36 sites in United States, France and 6 more
- Volunteers
- 300 people
- Sponsor
- Rijnstate Hospital
Acute Ischaemic Stroke
Endovascular Therapy in Acute Ischaemic Stroke Due to Large Vessel Occlusion
Aim of Study: 1. To develop a standardized patient selection criteria and imaging protocol for endovascular therapy in acute ischaemic stroke (AIS) 2.
- Trial name
- NCT03328403
- Testing
- Aspiration First, Stent retriever first
- Where
- Hong Kong
- Volunteers
- 58 people
- Sponsor
- The University of Hong Kong
Basilar Artery Occlusion, Acute Cerebrovascular Accident
Endovascular Treatment for Acute Basilar Artery Occlusion
Rationale: Recently, two prospective multicenter RCT reported a potential beneficial effect of endovascular thrombectomy (EVT) in patients with an acute symptomatic basilar artery occlusion (BAO).
- Conditions
- Basilar Artery Occlusion, Acute Cerebrovascular Accident, Stroke Due to Basilar Artery Occlusion
- Trial name
- NCT04751708
- Testing
- endovascular treatment, best medical management
- Where
- China
- Volunteers
- 340 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Gastrointestinal Vascular Conditions, Arteriosclerosis
Covered Stents Versus Bare-Metal Stents
To compare the outcome of revascularisation the gastrointestinal arteries using covered stents compared to bare-metal stents in patients with CGI.
- Conditions
- Gastrointestinal Vascular Conditions, Arteriosclerosis, Lifestyle-related Condition, Stenosis
- Trial name
- NCT02428582
- Testing
- Covered stent (Atrium Type V12), Bare stent (Brand Cordis Type Palmaz Blue)
- Where
- Netherlands
- Volunteers
- 84 people
- Sponsor
- Erasmus Medical Center
Acute Ischemic Stroke
The Improve Acute Reperfusion Treatment Quality for Ischemic Stroke Through Spatiotemporal Computing Thecnology in China
This study intends to construct the goal-oriented integrated intervention model through the intelligent bracelet automatic positioning and feedback system based spatiotemporal computing technology (FAST model) to promote the…
- Trial name
- IMPROVE-II (NCT06330051)
- Testing
- The goal-oriented integrated intervention model through the intelligent bracelet automatic positioning and feedback system based spatiotemporal computing technology (FAST model)
- Where
- China
- Volunteers
- 2,219 people
- Sponsor
- Beijing Tiantan Hospital
Aneurysm Cerebral, Endovascular Procedures
Optimal Duration of Dual Antiplatelet Therapy After Stent-assisted Coiling
Comparison of duration of dual antiplatelet therapy after stent-assisted coiling of unruptured intracranial aneurysms
- Trial name
- NCT05257824
- Testing
- Aspirin 100mg, Clopidogrel 75mg
- Where
- 8 sites in South Korea
- Volunteers
- 528 people
- Sponsor
- Seoul National University Bundang Hospital
Endovascular Treatment
Endovascular Treatment for AIS in Chinese Municipal and County Hospitals： A "Real World" Study-ETERNITY Registry
To investigate the Endovascular Treatment difference between Chinese city and country hospital.
- Trial name
- NCT06078917
- Where
- China
- Volunteers
- 1,196 people
- Sponsor
- Wen-huo Chen