Clinical trials: Endovascular Treatment
Stroke, Anesthesia
"GOLIATH" - General Or Local Anaestesia in Intra Arterial THerapy
Patients suffering a stroke with a large vessel occlusion is often treated intra veneous thrombolyse and on top of that also intra arterial therapy. It is unknown what form of anaestesia is best during intra arterial therapy.
- Conditions
- Stroke, Anesthesia, Cerebral Revascularization
- Trial name
- GOLIATH (NCT02317237)
- Testing
- Local anesthesia
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- University of Aarhus
Ischemic Stroke
Stroke Research Consortium in Northern Bavaria (STAMINA)
Each year, approximately 15 million people suffer a stroke worldwide of which 80% are due to ischemic cerebral infarction. Based on the results of randomized controlled trials, treatment options and patient outcomes in acute…
- Trial name
- STAMINA (NCT04357899)
- Testing
- thrombolysis therapy, endovascular therapy, decompressive surgery
- Where
- 2 sites in Germany
- Volunteers
- 3,769 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Subarachnoid Hemorrhage, Aneurysmal, Cerebral Vasospasm After Subarachnoid Hemorrhage
Endovascular Therapy for Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage
Cerebral vasospasm is a common and serious complication after aneurysmal subarachnoid hemorrhage and is an important cause of delayed cerebral ischemia and poor neurological outcomes.
- Trial name
- RESCUE-CV (NCT07643922)
- Testing
- Intra-arterial and Intravenous Milrinone Therapy, Standardized Medical Management
- Where
- 2 sites in China
- Volunteers
- 306 people
- Sponsor
- Beijing Tiantan Hospital
Acute Ischemic Stroke
Endovascular Treatment for Stroke Post 1 Day （24 Hours）
Acute ischemic stroke (AIS) is one of the leading causes of disability and mortality worldwide. The treatment of this condition is time-critical, with the key to effective therapy being the early recanalization of the occluded…
- Trial name
- ETP-1 (NCT06580730)
- Testing
- Endovascular treatment, Standard medical treatment
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Stroke, Ischemic, Stroke, Acute
A Randomized Trial of Imaging Selection Modalities for Stroke Thrombectomy (NO-SELECT)
Several studies suggest that advanced multi-modal imaging with CTP should be used to screen late time window stroke patients for thrombectomy. However, NCCT is more accessible when comparing with CTP.
- Trial name
- NCT05230914
- Testing
- Simplified imaging strategy, Standard imaging strategy
- Where
- 8 sites in China
- Volunteers
- 1,846 people
- Sponsor
- Xinqiao Hospital of Chongqing
Intracranial Aneurysm
Interest of Pre-operative Use of 3D Printing for Endovascular Treatment of Unruptured Intracranial Aneurysms With Intrasaccular Flow Disruptor
This is a preliminary randomised controlled trial comparing the use of pre-operative 3D models to select an intrasaccular flow disruptor for endovascular aneurysm cure.
- Trial name
- ILIAD (NCT05665309)
- Testing
- 3D anatomical model of aneurysm
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Cerebral Arteriovenous Malformations
Evaluation of ONYX in ENDOVASCULAR Treatment of Cerebral AVMs
To assess safety and efficacy of ONYX treatment for cAVM:
- Trial name
- cAVM (NCT02180958)
- Where
- 17 sites in France
- Volunteers
- 140 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Dural Arteriovenous Fistula
Treatment of Dural Arteriovenous Fistulas With SQUID™ Liquid Embolic Agent
The purpose of this study is assessment of safety, efficacy, and short-term outcome of SQUID™ in the embolization of Dural Arteriovenous Fistula
- Trial name
- Liquid (NCT03524976)
- Testing
- Squid
- Where
- 7 sites in Germany
- Volunteers
- 50 people
- Sponsor
- Dr. Markus Alfred Möhlenbruch
Cerebral Aneurysm
Acupoint Stimulation and Cranial Endovascular Treatment
In this prospective randomized controlled trial, the subjects will be assigned to group transcutaneous electrical acupoint stimulation (TEAS) and group control (no intervention).
- Trial name
- ASSET (NCT05413460)
- Testing
- transcutaneous electrical acupoint stimulation
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Zhihong LU
Hypertension
Endovascular Carotid Body Ablation in Patients With Treatment- Resistant Hypertension: A Safety and Feasibility Study
This is a prospective, observational, multicenter trial to evaluate the safety and feasibility of selective endovascular unilateral carotid body ablation in patients with treatment-resistant hypertension.
- Trial name
- NCT02099851
- Testing
- Carotid body ablation (Cibiem)
- Where
- 2 sites in Czechia, Poland
- Volunteers
- 6 people
- Sponsor
- Noblewell
Superficial Femoral Artery Stenosis, Claudication
Contribution of Optical Coherence Tomography in the Endovascular Treatment of Femoral Occlusions
This is a common care study. A study for evaluating the quality of balloon inflation and stent application will be performed in 2D angiography alone in the control group and then by 2D and OCT angiography for the experimental…
- Conditions
- Superficial Femoral Artery Stenosis, Claudication, Ischemic Leg
- Trial name
- TOCAF (NCT04434586)
- Testing
- femoropopliteal revascularization for TASC C or TASC D lesion
- Where
- France
- Volunteers
- 166 people
- Sponsor
- University Hospital, Lille
Aneurysm, Ruptured, Intracranial Aneurysm
Bare Platinum Coils Versus Second-generation Hydrocoils
Comparison of clinical and radiological outcomes between bare platinum coil group and second-generation hydrogel coils for treatment of ruptured intracranial aneurysms.
- Trial name
- NCT04988503
- Testing
- Coil embolization
- Where
- 3 sites in South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Acute Ischemic Stroke
COOLing of the Ischemic PENumbra in Patients With Acute Ischemic Stroke.
This study will develop and validate a novel, active/conductive combined head and neck cooling system to selectively cool the ischemic penumbra during the acute phase of stroke, reducing neuronal damage and improving stroke…
- Trial name
- PEN-Cool (NCT07844096)
- Testing
- PEN-Cool Conductive Head-and-Neck Cooling System, Standard Reperfusion Therapy / Routine Care
- Where
- 5 sites in India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Aneurysm Cerebral
Interest of a Simulated Procedure Performed on a Printed Model in the Endovascular Treatment of Carotid-sylvian Aneurysms
It is now considered that 1% to 2% of the French population has an intracranial aneurysm. The major risk of this malformation is essentially the rupture which will lead in 10% of cases to death immediately, in 30% to 50% death…
- Trial name
- Anev3D (NCT05419661)
- Testing
- Operational Pre-Planning
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Stroke, Acute, Neuroprotection
Normobaric Hyperoxia Combined With Endovascular Treatment in Acute Ischemic Stroke (OPENS-2)
The current endovascular treatment has increased the recanalization rate to more than 90%. Even so, the prognosis rate of stroke is still less than 50%.
- Trial name
- NCT04681651
- Testing
- Normobaric Hyperoxia, Endovascular Thrombectomy
- Where
- China
- Volunteers
- 282 people
- Sponsor
- Capital Medical University
Peripheral Vascular Diseases
Individual Patient Data Analysis of Viabahn for Peripheral Arterial Disease
To evaluate the effectiveness of the VSX device in pre-determined patient populations to understand the patient characteristics that impact outcomes.
- Trial name
- Insight-VSX (NCT05459818)
- Testing
- Viabahn implanted
- Where
- Netherlands
- Volunteers
- 977 people
- Sponsor
- Rijnstate Hospital
Vertebrobasilar Stroke
A Randomized Trial Of Endovascular Treatment For Acute Posterior Large Vessel Occlusion
The aim of this trial is to investigate whether endovascular treatment can improve the 90-day functional outcome of acute large vessel occlusion in the posterior circulation.
- Trial name
- BASILAR-2 (NCT04743076)
- Testing
- Endovascular treatment, Standard medical treatment
- Where
- 16 sites in China
- Volunteers
- 386 people
- Sponsor
- Xinqiao Hospital of Chongqing
Endovascular Carotid Surgery, Preoperative Hypotension
Compared Efficacy and Tolerance of Two Vasopressors Used to Treat Preoperative Hypotension During Carotid Surgery
The effects on brain perfusion of the two currently vasopressors used to treat accidental hypotension occurring during carotid surgery (i.e.
- Trial name
- VP-hTA-XCar (NCT01794273)
- Testing
- ephedrine and phenylephrine
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cardiac Resynchronization Therapy, Heart Failure
Comparison of Epicardial Versus Conventional Lead Placement in Cardiac Resynchronization Therapy
The primary goal of this study is to evaluate the use of robotically -assisted device leads as a primary strategy for heart resynchronization.This trials aims to compare transvenous lead placement with robotic lead placement for…
- Trial name
- REVERT (NCT01302470)
- Testing
- Primary epicardial placement of left ventricular lead, Transvenous placement of left ventricular lead
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Limb Salvage Rates With Endovascular Therapy
Endovascular Limb Salvage in Trinidad and Tobago
The purpose of this study was to investigate limb salvage rates in patients with critical limb ischemia after endovascular revascularization.
- Trial name
- NCT05547022
- Testing
- Endovascular revascularisation
- Where
- Trinidad and Tobago
- Volunteers
- 157 people
- Sponsor
- Naveen Seecheran