Clinical trials: Endovascular Treatment
Hypothermia, Heart Arrest
Clinical and Economical Interest of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA Study)
According to international guidelines, mild therapeutic hypothermia is recommended for resuscitated patients after cardiac arrest due to ventricular fibrillation.
- Trial name
- NCT00392639
- Testing
- Comparison of 2 cooling procedures
- Where
- France
- Volunteers
- 389 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hepatic Cancer, Metastatic Cancer
Prevention and Treatment of Complications of Endovascular Methods in Patients With Malignant Liver Tumors
In the structure of malignant liver lesions, two main groups are distinguished - primary liver cancer and metastatic liver damage. The five-year survival rate of patients with malignant liver tumors does not exceed 6%.
- Conditions
- Hepatic Cancer, Metastatic Cancer, Chemotherapy Effect
- Trial name
- PATOC (NCT04764409)
- Testing
- Chemoembolization, Chemoinfusion
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- Central Clinical Hospital RZD-Medicine, Russian Federation
AKI
Protection From Acute Kidney Injury (AKI) With Basis™ Treatment
This study is a single-center, prospective, randomized, double-blinded, placebo-controlled phase II clinical trial to evaluate the efficacy of "NAD+ supplementation" with Basis™ (Nicotinamide Riboside and Pterostilbene) in…
- Trial name
- NCT04342975
- Testing
- Nicotinamide Riboside + Pterostilbene
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Acute Ischemic Stroke
Infarct Growth After Intravenous Tocilizumab in Adults With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy - ILLUMINATE
The goal of this phase II, placebo-controlled intervention study is to investigate whether tocilizumab, an interleukin-6 (IL-6) receptor inhibitor, may have a neuroprotective effect by reducing infarct growth in adults with acute…
- Trial name
- Illuminate (NCT07870681)
- Testing
- Tociliuzumab
- Where
- 6 sites in Denmark, Norway
- Volunteers
- 156 people
- Sponsor
- Oslo University Hospital
Aortic Dissection Type B
EndoVascular Aortic Dissection Early vs Delayed
This is a prospective, multicenter, non-inferior, parallel-controlled observational study. This study aims to compare clinical outcomes of endovascular treatment for acute high-risk type B aortic dissection in the acute phase…
- Trial name
- EVADE (NCT07143071)
- Testing
- Acute Phase, Subacute Phase
- Where
- China
- Volunteers
- 4,068 people
- Sponsor
- Shanghai Zhongshan Hospital
Endovascular Repair of Aortic Aneurysm, Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities
Effects of Anesthetics on Postoperative Cognitive Function of Patients Undergoing Endovascular Repair of Aortic Aneurysm and Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities.
Endovascular repair of aortic aneurysm and endovascular treatment of arteriosclerosis obliterans of lower extremities are two kinds of common surgeries in the investigators' hospital.
- Trial name
- NCT02107170
- Testing
- Sevoflurane, Propofol, Remifentanil
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Tao Zhang
Atherosclerosis, Ischemia Limb
Efficacy and Safety Comparison of the Open Surgical and Endovascular Methods for the Treatment of Long Atherosclerotic Lesions of the Femoral-popliteal Segment Above the Knee, TASC II, Type D.
Endovascular revascularization and open bypass grafting above the knee show comparable results in primary 2-year patency (about 65%) in medium-length lesions - TASC II, C (Pereira et al, 2006).
- Conditions
- Atherosclerosis, Ischemia Limb, Superficial Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- NCT04588571
- Testing
- Endovascular recanalization with angioplasty and stenting with the biomimetic interwoven nitinol stent, Femoropopliteal proximal bypass
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Polytrauma, Hypothermia
Forced Air Versus Endovascular Warming in Polytrauma Patients
Trauma is the leading cause of death in young adults, bleeding and infection are major concomitant problems. We test the hypothesis that fast, perioperative warming with an endovascular catheter versus forced air warming may…
- Trial name
- FAEWPP (NCT00555126)
- Testing
- Forced Air Warming, Warming with endovascular catheter + forced air warming
- Where
- 2 sites in Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Stroke, Ischemic Stroke
Feasibility Study of IV Recombinant Tissue Plasminogen Activator (rtPA) vs. Primary Endovascular Therapy for Acute Ischemic Stroke
This pilot trial will be the first step toward direct comparison of delivery of endovascular reperfusion therapy to intravenous recombinant tissue plasminogen activator (rt-PA) in a time-to-treatment framework shown as most…
- Trial name
- EARLY (NCT01869478)
- Testing
- Intravenous Thrombolysis, Endovascular Arterial Reperfusion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Hemodialysis Access Failure
Effectiveness of Endoluminal Treatment of Autologous Arteriovenous Endovascular Fistula Failure
This study was aimed at comparing the efficacy and safety of cutting balloons versus drug-coated balloons in treating venous segment stenosis of autologous arteriovenous fistulas.This is a prospective, multi-center cohort study.
- Trial name
- NCT06493292
- Testing
- Endovascular therapy
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- RenJi Hospital
Neurology, Interventional Therapy
A Retrospective Study of Reco Thrombectomy Stent for Intravascular Treatment of Acute Ischemic Stroke
To explore the differences in the green channel process of stroke in various regions of the same province, to target and shorten the time delay of emergency process, and to explore the key technologies of endovascular treatment…
- Trial name
- NCT05166733
- Where
- China
- Volunteers
- 300 people
- Sponsor
- PengYa
Acute Anterior Myocardial Infarction
Rapid Intravascular Cooling in Myocardial Infarction as Adjunctive to Percutaneous Coronary Intervention
Rapid MI-ICE-Pilot is designed to demonstrate the safety and efficacy of the Celsius Control™ System (CCS) endovascular catheter to reduce the infarct size resulting from acute anterior myocardial infarction when used in…
- Trial name
- NCT00417638
- Testing
- Endovascular cooling by the Celsius Control System, Standard of care
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- ZOLL Circulation, Inc., USA
Acute Ischemic Stroke
Collateral-based reSetting of Endovascular Treatment Time Window for Stroke (CoSETS)
This study is a prospective, partly randomized, multi-center, Phase III, controlled trial, designed to show that the onset-to-puncture time (OPT) for good functional outcome (defined by modified Rankin Scale score at 3 months…
- Trial name
- NCT03234634
- Testing
- endovascular thrombectomy
- Where
- South Korea
- Volunteers
- 291 people
- Sponsor
- Yonsei University
Hydrocephalus, Communicating, Hydrocephalus
The ETCHES I Study (Endovascular Treatment of Communicating Hydrocephalus With an Endovascular Shunt)
The eShunt™ System is a minimally invasive method of treating communicating hydrocephalus. The eShunt System includes a proprietary eShunt Delivery System and the eShunt Implant, a permanent implant deployed in a minimally…
- Trial name
- ETCHES I (NCT04758611)
- Testing
- eShunt™ Implant
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- CereVasc Inc
Peripheral Vascular Disease, Critical Limb Ischemia
Near Infrared Spectroscopy and Transcutaneous Oxygen Pressure in Critical Limb Ischemia Before and After Treatment
Comparison of two non-invasive methods for measuring tissue oxygenation. One is Transcutaneous Oxygen Pressure (TCPO2) and the other is the new method of Near Infrared Spectroscopy (NIRS) - near infrared spectroscopy in patients…
- Trial name
- NIRS (NCT01459341)
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Carmel Medical Center
Submassive Pulmonary Embolism
Long Term Effects of Treating Submassive Pulmonary Embolism With Ultra-sound Accelerated Thrombolysis
Patients with Submassive Pulmonary Embolism treated with ultra-sound therapy will have an improved right ventricular function 72 hours post treatment.
- Trial name
- SPEAR (NCT01899339)
- Testing
- submassive PA treatment with Ekosonic endo device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Corewell Health West
Ischemic Stroke
Change in Serum Biomarkers After Endovascular Treatment for Acute Anterior Circulation Large Vessel Occlusion
Acute ischaemic stroke (AIS) results in high rates of neurological morbidity and mortality, especially in patients with large vessel occlusion (LVO).
- Trial name
- NCT06383182
- Testing
- endovascular treatment
- Where
- China
- Volunteers
- 800 people
- Sponsor
- General Hospital of Shenyang Military Region
Ischemic Stroke
Effectiveness of NIRS (Near-Infrared Spectroscopy) at Acute Ischemic Stroke Patients
Near-infrared spectroscopy (NIRS) is a non-invasive technology that continuously monitors regional tissue oxygenation (tissue saturation with oxygen).
- Trial name
- NCT04904172
- Testing
- Masimo O3 Regional Oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ege University
Peripheral Arterial Disease
Outcomes of Endovascular Treatment of Superficial Femoral Artery In-stent Restenosis
Lower limb peripheral arterial disease (PAD) is a common, important manifestation of systemic atherosclerosis. Stenosis or occlusions in the superficial femoral artery (SFA) may result in intermittent claudication or even…
- Trial name
- NCT04123639
- Testing
- PTA
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intracranial Aneurysm, Stent Complication
Stent-Assisted Coiling Followed by Ticagrelor Monotherapy Instead of Dual Antiplatelet Therapy in Unruptured Intracranial Aneurysm
The primary goal of the trial is to investigate whether the experimental arms (receiving the P2Y12 inhibitor Ticagrelor) compared with the control arm (taking dual antiplatelet therapy) could reduce bleeding complications in…
- Trial name
- SAC-TIDE (NCT06015477)
- Testing
- Ticagrelor monotherapy, Dual Antiplatelet Therapy
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University