Clinical trials: Endurance
Age-related Muscle Decline
CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy
This Phase 1/2a, open-label, non-randomized study is designed to evaluate the safety and tolerability of intramuscular AAV9-Follistatin gene therapy administered either as monotherapy or in combination with a VEGF-encoding…
- Trial name
- CALM-AF-AI (NCT07443826)
- Testing
- AAV9-Follistatin gene therapy, VEGF Plasmid
- Where
- Honduras
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Unlimited Biotechnology LLC
Supplement, Endurance Cycling Performance
Effect of a Supplement Containing Olive Leaf Extract and Vitamins on Performance of Male Elite Cyclists
The study focuses on olive leaf extract, particularly its active component, Oleuropein, which has shown promise in enhancing energy metabolism and muscle performance in previous studies.
- Conditions
- Supplement, Endurance Cycling Performance, Endurance Exercise, Performance
- Trial name
- NutriRide (NCT06741163)
- Testing
- Pre-activity shot
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Fatigue
The Effects Assessment of the Polygonatum Kingianum Extract on Endurance Performance and Anti-fatigue
To assess the efficacy of polygonatum kingianum extract on endurance performance and anti-fatigue
- Trial name
- NCT05877677
- Testing
- Polygonatum kingianum extract drink
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Diabetes Mellitus, Glucose Metabolism Disorders
Effects of Simulated Passive Jogging Device on Glucose Homeostasis, Muscle Strength and Endurance
Physical Inactivity and excessive sedentary behavior are risk factors for diabetes and cardiovascular disease. Movement is important for overall health.
- Conditions
- Diabetes Mellitus, Glucose Metabolism Disorders, Physical Activity
- Trial name
- NCT03550105
- Testing
- Gentle Jogger
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sackner Wellness Products LLC
Healthy
Effects of Mitopure (Urolithin A) on Skeletal Muscle Function, Iron Metabolism and Endurance Performance
This is a randomized, double-blind, placebo-controlled study enrolling 36 (16 Elite and 20 Sub-Elite trained endurance runners (18 placebo and 18 Mitopure intervention) who are 18-40 years of age.
- Trial name
- ENDURO (NCT04783207)
- Testing
- Mitopure
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Pulmonary Disease, Chronic Obstructive
Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients.
The primary objective of this trial is to investigate the effect of 6 weeks treatment with tiotropium + olodaterol fixed dose combination inhalation solution on lung hyperinflation and exercise tolerance in patients with COPD.
- Trial name
- NCT01533935
- Testing
- Tiotropium + Olodaterol, Tiotropium, Olodaterol
- Where
- 33 sites in United States, Argentina and 6 more
- Volunteers
- 291 people
- Sponsor
- Boehringer Ingelheim
Oxidative Stress, Muscle Strength
The Effects of Antioxidant Supplementation on Multiple Endurance Race Performance, Physiology, and Recovery.
Thirty active male and female athletes will be recruited for the study. Subjects will be examined at baseline for VO2max performance.
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Body Composition
- Trial name
- NCT04314596
- Testing
- Cross Training Course, Oceanix
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Chronic Heart Failure
The HeartWare™ Ventricular Assist System as Destination Therapy of Advanced Heart Failure: the ENDURANCE Trial
The purpose of this study is to determine the safety and effectiveness of the HeartWare Ventricular Assist System in patients with chronic Stage D/ New York Heart Association (NYHA) Class IIIB/IV left ventricular failure who have…
- Trial name
- ENDURANCE (NCT01166347)
- Testing
- HeartWare® VAS, Control LVAD
- Where
- 48 sites in United States
- Volunteers
- 451 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety of Aclidinium Bromide 400 µg BID (Twice a Day)Compared to Placebo in Patients With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
The aim of the present study is to evaluate the effect of aclidinium bromide 400 μg twice a day (BID) administered twice a day versus placebo on exercise endurance and on hyperinflation and dyspnoea at rest and during exercise…
- Trial name
- NCT01471171
- Testing
- Aclidinium Bromide
- Where
- 14 sites in Germany, Spain and 1 more
- Volunteers
- 112 people
- Sponsor
- AstraZeneca