Clinical trials: Energy Expenditure
Mitochondrial Diseases, Mitochondrial Myopathies
Human Mitochondrial Stress-driven Obesity Resistance
The overarching aim of this observational study is to determine alterations in energy balance while exploring the underlying cellular mechanisms in human genetic models of mitochondrial stress.
- Conditions
- Mitochondrial Diseases, Mitochondrial Myopathies, Mitochondrial Disorder
- Trial name
- MITO-OB-RES (NCT06080568)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Cerebral Ischemia
Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral Ischemia
The purpose of this study is to evaluate safety and efficacy of sequential treatment with Mexidol® in patients with chronic cerebral ischemia (CCI).
- Trial name
- MEMO (NCT06834490)
- Testing
- Mexidol
- Where
- 14 sites in Russia, Uzbekistan
- Volunteers
- 318 people
- Sponsor
- Pharmasoft
Spastic Diplegia
Effect of Vestibular Rehabilitation on Postural Sway and Energy Expenditure in Children With Spastic Diplegia
this study will be conducted To determine the effect of vestibular rehabilitation training on postural sway and energy expenditure in children with spastic cerebral palsy and To determine any relation between postural sway and…
- Trial name
- NCT07617935
- Testing
- vestibular rehabilitation, conventional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Weight
Energy Expenditure Assessment of Premature Infants
The goal of this study is verify if the energy expenditure in preterm infant fed with human milk is different from preterm formula.
- Trial name
- NCT00769509
- Testing
- energy expenditure in preterm fed with preterm formula, assessment of energy expenditure
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Oswaldo Cruz Foundation
Preterm Infants
Energy Expenditure in Breast and Bottle Feeding Preterm Infants Fed Their Mother's Breast Milk
OBJECTIVE. Neonatologists consider early feeding at the breast to be too tiring for preterm infants, although there is no evidence that this is actually the case.
- Trial name
- NCT00838188
- Testing
- Way of Feeding - Breast feeding vs. Bottle feeding
- Where
- 2 sites in Israel
- Volunteers
- 23 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Bone Marrow Transplantation, Hematopoietic Stem Cell Transplantation
Evolution of the Energy Expenditure During Hematopoietic Stem Cell Transplantation
The treatment before bone marrow transplantantion is initiated by chemotherapy associated or not with radiotherapy, both of which cause various side effects on the patient as symptoms that impair food intake.
- Trial name
- NCT04535570
- Testing
- Indirect Calorimetry
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Minas Gerais
Critical Illness
The ICALIC International Multicentric Study
This study will evaluate the ease of use of the new calorimeter (Q-NRG (COSMED, Italy)) in intensive care unit (ICU) patients compared to currently used calorimeters (i.e.
- Trial name
- ICALIC (NCT02796430)
- Testing
- Time needed to start indirect calorimetry measurement, Indirect calorimetry measurement
- Where
- 7 sites in Austria, Belgium and 4 more
- Volunteers
- 272 people
- Sponsor
- University Hospital, Geneva
Endurance Cycling Performance
The Effect of Diet Composition on Performance, Expenditure, Blood Lipids, and Appetite Hormones in Highly Trained Cyclists
This study employs a crossover design to evaluate the effect of two different diets (high carbohydrate vs. ketogenic) and corresponding test meals on endurance exercise performance, energy expenditure including resting metabolic…
- Trial name
- DCAP (NCT04097171)
- Testing
- Diet
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Healthy
Physiologic Effect of Spices Ingestion
Human studies have shown that capsaicin, a compound extracted from chilly peppers, can stimulate certain physiologic functions (for example, energy expenditure, thermogenesis, lipid oxidation, heart rate, etc.).
- Trial name
- NCT02193438
- Testing
- Spices intake
- Where
- Switzerland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Cystic Fibrosis
Study of Total Energy Expenditure in Infants and Children With Moderate to Severe Cystic Fibrosis
OBJECTIVES: I. Compare the resting energy expenditure using respiratory calorimetry in infants and children with moderate to severe cystic fibrosis versus age matched healthy controls. II.
- Trial name
- NCT00006273
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Alzheimer's Disease (AD)
Trial of Oxaloacetate in Alzheimer's Disease (TOAD)
The purpose of this study is to determine if oxaloacetate (OAA) is safe and tolerable at doses of up to 2 grams per day in people with Alzheimer's disease (AD).
- Trial name
- TOAD (NCT02593318)
- Testing
- Oxaloacetate (OAA) 1g, Oxaloacetate (OAA) 2g
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Russell Swerdlow
Type 2 Diabetes Mellitus, Obesity
Type 2 Diabetes and Obesity in Mexican Pimas: Gene-Environment Interaction
In 1995 we conducted a cross-sectional study to identify the effects of traditional and western environments on prevalence of type 2 diabetes mellitus (T2DM) and obesity in Pima Indians in Mexico and the United States.
- Trial name
- NCT01168297
- Where
- Mexico
- Volunteers
- 657 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Respiration, Artificial, Energy Metabolism
Energy Expenditure in Weaning From Mechanical Ventilation
During weaning from mechanical ventilation process, the energy expenditure in T tube is greater than pressure support ventilation.
- Trial name
- NCT00853060
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cerebral Palsy
Loaded Vs Unloaded Sit to Stand Strengthening Exercises in Children With Cerebral Palsy
Cerebral palsy(CP) is non-progressive disorder, undergo mishap to the developing brain and it affect a person's ability to move and maintain balance and posture. Old name of CP is "Little's disease".
- Trial name
- NCT06190418
- Testing
- Loaded sit to stand strengthening exercise, Unloaded sit to stand strengthening exercise
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Resting Metabolic Rate, Metabolism Disorders
Family Patterns in Resting Metabolic Rate Between Parents and Adult Children
This study examines whether resting metabolic rate (RMR)-the amount of energy the body uses at rest-is similar between biological parents and their adult children (aged 18 years and older).
- Trial name
- NCT07594613
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Obstructive Sleep Apnea
Validation of Sleep Healthcare System
The present project aims to that examine the interplay between sleep duration circadian phase, and metabolic regulation. The impact of CPAP therapy on metabolic regulation is assessed with a RCT.
- Trial name
- NCT04252482
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Constitutional Growth Delay, Nutrition Disorders
Nutrients and Hormones: Effects in Boys With Disordered Growth
The purpose of the study is to find out if patients with constitutional delay of growth have a mismatch between energy intake and utilization (as measured by doubly labeled water) and to compare the improvement in growth and…
- Conditions
- Constitutional Growth Delay, Nutrition Disorders, Growth Disorders
- Trial name
- NCT00139451
- Testing
- Pediasure, GH
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Parkinson's Disease
Body Weight Gain, Parkinson, Subthalamic Stimulation
Chronic bilateral subthalamic stimulation leads a spectacular clinical improvement in patients with motor complications. However, the post-operative body weight gain involved may limit the benefits of surgery and induce critical…
- Trial name
- NCT00529724
- Testing
- Energy metabolism by chronic bilateral subthalamic stimulation
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Clermont-Ferrand
Bipolar Depression
Lamotrigine Therapy in Geriatric Bipolar Depression
We propose to study the efficacy and tolerability of lamotrigine in the treatment of older adults with bipolar depression and to compare measures of brain energy metabolism between older subjects with bipolar depression and…
- Trial name
- NCT00720473
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Menstrual Dysfunction
Stress and Menstrual Health
The goal of this experimental study is to determine how stressors that do not directly impact energy state or energy demands (hereafter called "non-energetic stressors") affect reproductive health in pre-menopausal women.
- Trial name
- NCT07566260
- Testing
- Heat stress, Sleep stress, Exercise stress
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Duke University