Clinical trials: Energy Expenditure, open to volunteers
Obesity
Probiotic for Weight Management in Overweight and Obese Adults
To evaluate the impact of pasteurized Akkermansia muciniphila Akk11 capsules versus placebo on body composition (including body weight, BMI, body fat percentage, waist-to-hip ratio, wrist circumference, visceral fat area, and…
- Trial name
- NCT07507929
- Testing
- Probiotic
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Obesity
Weight Loss Composition and Metabolic Adaptation During Hypocaloric Dieting
Weight loss induced by hypocaloric dietary interventions is commonly accompanied by reductions in resting metabolic rate (RMR), a phenomenon often described as metabolic adaptation.
- Trial name
- NCT07627256
- Testing
- Hypocaloric Diet
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Obesity, Weight Change, Body
Linking Temporal Patterns of Modifiable Behaviors to Weight Loss Outcomes
This study is designed as an observational trial. The objective of this study is to follow-up with participants 3 years after completion of an 18-month comprehensive behavioral weight loss intervention.
- Trial name
- NCT03840733
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Anorexia Nervosa
Hormonal And Metabolic Signatures In Human Hypothalamic Neurons In Anorexia Nervosa
The goal of this observational study is to investigate cellular mechanisms of neuroendocrine and metabolic signaling in adult women with anorexia nervosa (AN) compared to healthy controls.
- Trial name
- HOPE (NCT07580209)
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maria Miletta
Bipolar I Disorder, Depression, Anxiety
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
This is a randomized, double-blind, placebo-controlled proof-of-concept clinical trial to assess the efficacy and safety of Magnesium-vitamin B6in combination with treatment as usual for treating symptoms of depression, stress…
- Conditions
- Bipolar I Disorder, Depression, Anxiety, Stress
- Trial name
- NCT05837104
- Testing
- Magnesium vitamin B6
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mclean Hospital
Resting Metabolic Rate, Energy Metabolism
Observing Performance of Haptic Vibrotactile Trigger Technology by Measuring Changes in Resting Metabolic Rate: Assessment and Analysis
This study evaluates whether a drug-free, non-invasive topical patch embedded with Haptic Vibrotactile Trigger Technology (VTT) - the IGNITE Patch (The Super Patch Company) - is associated with changes in resting metabolic rate…
- Conditions
- Resting Metabolic Rate, Energy Metabolism, Haptic Technology, Vibrotactile Stimulation
- Trial name
- OPTIMA (NCT07781384)
- Testing
- IGNITE Patch (Active), Inactive patch
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SuperPatch Limited LLC
Energy Expenditure, Physical Activity
The ENERGYCO Study
The aims of this school-based cycling intervention called "ENERGY Commuting to school" (ENERGYCO) will be divided into two phases: Phase I will aim: 1) to design, test, and validate predictive equations for the objective…
- Conditions
- Energy Expenditure, Physical Activity, Behavior, Body Composition
- Trial name
- ENERGYCO (NCT06414668)
- Testing
- Cycling Intervention Group
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Diet-induced Thermogenesis
Inter-Individual Variability in Early Diet-Induced Thermogenesis After a Standardized Meal
This study aims to characterize how individuals differ in their metabolic response to food intake, specifically focusing on early diet-induced thermogenesis (DIT).
- Trial name
- NCT07610759
- Testing
- Standardized Liquid Meal
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Constitutional Thinness
Energy Expenditure and Neuromuscular Function in Young Adult Women With a Naturally Thin Build (LeanErgy)
People with a low BMI (<17.5) are most often considered to have anorexia nervosa (AN). However, recent literature suggests that there is a category of individuals with the same low BMI who do not meet the diagnostic criteria for…
- Trial name
- LeanErgy (NCT07233109)
- Testing
- Evaluation of the maximum oxidation point of lipids, Evaluation of the energy cost of walking, Neuro-muscular assessments
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Emile Roux
Resting Metabolic Rate, Energy Metabolism
Within-Individual Variability of Resting Metabolic Rate Over 12 Weeks
This prospective observational study aims to characterize within-individual variability in resting metabolic rate (RMR) over a 12-week period using high-frequency repeated measurements under standardized conditions.
- Trial name
- NCT07628764
- Testing
- Repeated Measurement of Resting Metabolic Rate
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Postmenopause, Energy Expenditure
Resting Energy Expenditure in Postmenopausal Women
Obesity and its associated comorbidities are rising at an alarming rate, particularly among postmenopausal women. Menopause, characterized by a decline in estradiol and progesterone levels, is often accompanied by weight gain.
- Conditions
- Postmenopause, Energy Expenditure, Hormone Replacement Therapy
- Trial name
- MenoBOLISM (NCT06905886)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Refeeding Syndrome, Critical Illness
Respiratory Quotient and Phosphate Changes During Early Critical Illness
Critically ill patients often experience major changes in metabolism during the first days of intensive care. When nutrition is started or increased after a period of reduced intake, some patients may develop refeeding syndrome…
- Conditions
- Refeeding Syndrome, Critical Illness, Metabolic Changes During Critical Illness
- Trial name
- IC-REFEED (NCT07800143)
- Testing
- Nutritional Exposure During Early Critical Illness
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Overweight and Obese Adults, Healthy
Sex Hormones as Regulators of the Age- and Sex-dependent Benefits of Caloric Restriction
Obesity increases the risk of type 2 diabetes, cardiovascular disease, and certain cancers, primarily due to elevated abdominal fat storage.
- Trial name
- GendAge (NCT07065643)
- Testing
- Phase 1 - Maintenance Diet, Phase 2 - Weight loss diet
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Bone Remodeling, Energy Metabolism
Retrospective Monocentric Evaluation of Biomarkers Associated With Bone, Muscle and Energy Metabolism
Bone is a metabolically active tissue undergoing continuous remodeling through the coordinated actions of osteoclasts (resorption), osteoblasts (formation), and osteocytes (regulation).
- Trial name
- OVAD (NCT07454252)
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Malnutitrion, Cancer
Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients
This study compares two methods of prescribing parenteral nutrition (PN) in adults with cancer who are unable to meet nutritional needs by oral or enteral intake.
- Trial name
- NCT07776704
- Testing
- Indirect Calorimeter, Weight-Based Parenteral Nutrition Dosing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fox Chase Cancer Center
Stroke, Chronic Stroke Patients
Development and Validation of an Actimetric Protocol to Quantify Physical Activity and Sedentary Behaviour in Post-stroke Subjects
The aim of this project is to develop an actimetry protocol based on a system of motion sensors, such as accelerometers and pressure insoles.
- Conditions
- Stroke, Chronic Stroke Patients, Stroke With Hemiparesis
- Trial name
- ActiStroke (NCT06943014)
- Testing
- Actimetry Protocol
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Healthy Subjects or Volunteers
Hydrogen-Rich Water and Resting Metabolism in Young Adults
The H2REST trial is a randomized, double-blind, placebo-controlled crossover study investigating the acute effects of a single dose of hydrogen-rich water (HRW) on resting metabolism in healthy young adults.
- Trial name
- H2REST (NCT07098221)
- Testing
- Molecular Hydrogen
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad
Resting Metabolic Rate, Metabolism Disorders
Family Patterns in Resting Metabolic Rate Between Parents and Adult Children
This study examines whether resting metabolic rate (RMR)-the amount of energy the body uses at rest-is similar between biological parents and their adult children (aged 18 years and older).
- Trial name
- NCT07594613
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Obesity, Underweight
Experimental Approach to Test Predictions of Body Weight Regulation Models
The regulation of human body weight and fatness is not fully understood. Although some models of regulation have been proposed (set point, dual-intervention point, others), no studies have been designed to test their predictions.
- Trial name
- DIP (NCT06309576)
- Testing
- Fasting-refeeding cycle
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Exercise, Fatigue
Physiological Responses to Basketball-Specific Interval Exercise in Female Basketball Players
This study aims to evaluate the effects of interval exercise on metabolic and inflammatory responses, energy substrate utilization, and fatigue in trained female basketball players.
- Conditions
- Exercise, Fatigue, Sport Physiology
- Trial name
- INTER-BASKET (NCT07752459)
- Testing
- Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1)
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education