Clinical trials: Energy Metabolism
Cardiovascular Diseases, Heart Diseases
Energy Expenditure, Diet and Body Fat in Children
To characterize the pattern of change over a two year period in energy expenditure and energy intake in two cohorts of American Indian (AI) children.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00024817
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Type 1 Diabetes, Obesity
Manchester Intermittent and Daily Diet Type 1 Diabetes App Study (MIDDAS-Type 1)
To assess the safety, acceptability and feasibility of testing Intermittent Low Energy Diet (ILED) and Continuous Low Energy Diet (CLED) programmes for 12 weeks in a real life setting with people with T1D and obesity.
- Trial name
- MIDDAS T1 (NCT04674384)
- Testing
- Optifast meal replacement shakes
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Manchester University NHS Foundation Trust
Obesity
Potato Consumption and Energy Balance
A randomized, clinical trial will be performed to assess changes in body weight and fat mass with daily potato consumption versus a calorie-matched snack of almonds.
- Trial name
- NCT03518515
- Testing
- White potato (french fries), White potato (French fries), +seasoning, Almond
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Elevated Triglycerides, Hypertriglyceridemia
Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado
The objective of this study is to assess the effects of replacing energy from SoFAS with energy from avocado on non-high-density lipoprotein cholesterol (non-HDL-C) and other aspects of the cardiometabolic health profile…
- Trial name
- NCT04990817
- Testing
- Average American Diet With SoFAS Replaced With Avocado, Average American Diet
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Total Caloric Intake, Nutrient Dense Caloric Intake
The Presence of Friends Increases Food Intake in Youth
Participants will be matched with either their friend or an unfamiliar peer who is the same gender and about the same age. Participants will have 45 minutes of free-play in an experimental room where they will have free access to…
- Conditions
- Total Caloric Intake, Nutrient Dense Caloric Intake, Energy Dense Caloric Intake
- Trial name
- NCT00874055
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Respiratory Insufficiency in Children, Noninvasive Ventilation
Validation of Indirect Calorimetry in Children Undergoing Non-invasive Ventilation
Nutritional status in critically ill pediatric patients is considered a fundamental prognostic factor in terms of mortality, morbidity, complications and outcome.
- Conditions
- Respiratory Insufficiency in Children, Noninvasive Ventilation, Nutrition Assessment
- Trial name
- CALO-NIV (NCT03824249)
- Testing
- Indirect Calorimetry
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Obesity, Bariatric Surgery Candidate
Investigating the Role of Ghrelin in Regulating Appetite and Energy Intake in Patients Following Bariatric Surgery (BARI-INSIGHT)
Bariatric surgery helps patients with severe obesity to lose weight, cures and prevents diseases linked to obesity and reduces the risk of death.
- Conditions
- Obesity, Bariatric Surgery Candidate, Appetitive Behavior
- Trial name
- BARI-INSIGHT (NCT03641417)
- Testing
- GLWL-01
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University College, London
Obesity
Metabolic Effects of a Caloric Restriction High/Low Glycemic Index Diet Plus Metformin in Overweight/Obese Subjects
The prevalence of obesity and Type 2 diabetes has increased dramatically worldwide. Research on Glycemic Index (GI) diets has been largely developed, however the combination with metformin in humans was not investigated yet.
- Trial name
- NCT01460797
- Testing
- Glycemic Index Diets and Metformin hydrochloride
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Caio Eduardo Gonçalves Reis
Overweight and Obesity
Biking vs. Running: Comparison of EPOC, Substrate Oxidation, Appetite and Energy Intakes in Men With Overweight/Obesity.
The management of obesity involves hygienic and dietary measures that include appropriate nutrition and an increase in physical activity (PA).
- Trial name
- BIKERUN (NCT06082310)
- Testing
- Exercise
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Cardiovascular Diseases, Natriuretic Peptides
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes…
- Conditions
- Cardiovascular Diseases, Natriuretic Peptides, Cardiometabolic Diseases, Energy Expenditure
- Trial name
- NCT05216042
- Testing
- Study diet, Exercise capacity VO2 max determination, Exercise Challenge
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sleep, Physical Fitness
Fitness and Sleep in People With Family History of Type 2 Diabetes.
Currently, it is not known if the amount of nighttime sleep has any effect on the overall physical fitness, and on how much energy do people who have a relative with type 2 diabetes (parent, sibling, or grandparent) use to…
- Conditions
- Sleep, Physical Fitness, Type 2 Diabetes
- Trial name
- NCT00721084
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Obesity, Energy Balance
Activity, Adiposity, and Appetite in Adolescents 2 Intervention
The objective of the study is to quantify the relationship between physical activity, metabolic function, and appetite in adolescents.
- Conditions
- Obesity, Energy Balance, Appetite, Metabolism
- Trial name
- AAAA2INT (NCT05443347)
- Testing
- Aerobic exercise, Newsletter
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Diet, Healthy, Eating Behavior
The Impact of Food Reformulation on Energy Intake
Food prepared outside of the home tends to have a high energy content, and high levels of nutrients of concern (sodium, fat, saturated fat and sugar), especially when compared to home-cooked food.
- Conditions
- Diet, Healthy, Eating Behavior, Obesity
- Trial name
- NCT05744050
- Testing
- Low energy density lunch, Medium energy density lunch, High energy density lunch
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Protein-Energy Malnutrition, Anorexia
Energy Dense Formula to People Living in Old Peoples Home
Dietary intake in frail elderly is often lower than estimated needs due to the combined effects of the anorexia of ageing, frailty and the presence of acute and chronic disease.
- Conditions
- Protein-Energy Malnutrition, Anorexia, Weight Change
- Trial name
- NCT01259999
- Testing
- Calogen extra strawberry
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska University Hospital
Osteopenia (Disorder), Apnea of Prematurity
Effect of Caffeine on Preterm Infants' Bone Mineral Content
The primary objective was to determine whether caffeine therapy is associated with decreases bone mineral content using dual energy x-ray absorptiometry.
- Trial name
- NCT03084432
- Testing
- Dual Energy X-ray Absorptiometry
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Renal Cell Cancer, Fatigue
Study of Muscle Energy Metabolism in RCC Patients Treated With Sunitinib
Sunitinib is a chemotherapy approved by the FDA as a standard of care treatment for renal cell carcinoma (RCC). Fatigue is a very common side effect of sunitinib that frequently causes dose reductions.
- Trial name
- NCT02428335
- Where
- Canada
- Sponsor
- AHS Cancer Control Alberta
Energy Metabolism
Erythrocyte Transport of Lactate During Exercise (TELE Project)
The goals of this clinical trial are: 1. to study lactate kinetic between plasma and erythrocytes during an intervallic exercise and its subsequent recovery, considering the blood pH, the genotype for the T1470A polymorphism of…
- Trial name
- TELE (NCT06104150)
- Testing
- Intervallic submaximal exercise test
- Where
- 2 sites in Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Temperature, Clothing
Measuring Free-living Energy Expenditure Using Direct Calorimetry
Although instruments such as pedometers and heart rate monitors are helpful for those who use exercise to maintain their weight, they do not actually measure calories expended, which is a critical piece of information necessary…
- Conditions
- Temperature, Clothing, Sex, Age
- Trial name
- NCT01454882
- Testing
- Effects of Clothing, Effects of Temperature, Low Physical Activity
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Acromegaly, Growth Hormone Deficiency
Cardiac and Skeletal Muscle Energy Metabolism in Abnormal Growth Hormone States
Growth hormone (GH) is important for growth in childhood, but also has important effects on a number of tissues throughout life.
- Trial name
- NCT00461240
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Barts & The London NHS Trust
Resting Energy Expenditure, Chronic Kidney Disease
Novel Equation for Estimating Resting Energy Expenditure
The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients.
- Trial name
- NCT03377413
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital