Clinical trials: Enhanced Care
Colorectal Cancer
Community Partnership for Telehealth Solutions to Convey Information and Enhance Care
Non-randomized, two-arm stepped-wedge trial of a multi-level colorectal cancer screening intervention.
- Trial name
- PRIME (NCT06542835)
- Testing
- Video text message, In-clinic CRC screening promotion, Mailed FIT
- Where
- United States
- Volunteers
- 15,128 people
- Sponsor
- University of Arizona
Bladder Cancer, Quality of Life
Impacts and Testing of the "Multi-domains Active-living Program" in Operable Non-Muscle Invasive Bladder Cancer Patients
Among bladder cancer, the majority of them (70%) are non-muscle-invasive bladder cancer (NMIBC). The survival time is even longer in NMIBC. Patients with NMIBC receive surgery or transurethral resection of bladder tumor (TURBT).
- Trial name
- NCT05739968
- Testing
- Usual care + oncology case manager (OCM) care, Multi-domains Active-living Program (MAP) with e-health enhanced intervention + usual care + oncology case manager (OCM) care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Surgery, Post Operative Complications
Enhanced Vitals Monitoring After Major Surgery Trial
The aim of this clinical trial is to examine the feasibility of an enhanced vital sign monitoring solution in-hospital and at-home. This study includes adult patients undergoing inpatient major vascular or abdominal surgery.
- Conditions
- Surgery, Post Operative Complications, Quality of Recovery, General Surgery
- Trial name
- NCT06584825
- Testing
- Enhanced Vitals Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- University of British Columbia
Carcinoma, Non-Small-Cell Lung
Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib
The purpose of this study is to evaluate whether enhanced dermatologic management can reduce incidence of grade greater than or equal to (>=) 2 dermatologic adverse events of interest (DAEIs) when compared with standard-of-care…
- Trial name
- COCOON (NCT06120140)
- Testing
- Amivantamab IV, Amivantamab SC, Lazertinib
- Where
- 93 sites in United States, Argentina and 9 more
- Volunteers
- 305 people
- Sponsor
- Janssen Research & Development, LLC
Primary Breast Cancer
Effectiveness of the CHESS eHealth Cancer Support Intervention in Population-based Care
The study's aim is to provide information about the clinical and business cases for comprehensive interactive cancer communication systems (ICCS) in the context of real world use for cancer care.
- Trial name
- NCT01033162
- Testing
- Enhanced ICCS with KPNW web resources and the Comprehensive Health Enhancement Support System (CHESS.)
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus
Mobile Application to Enhance Diabetic Care
Prospective study to evaluate whether or not an internet application to coordinate and record diabetes management by the 1. diabetic patient/family caregiver 2. diabetic medical care team and 3.
- Trial name
- NCT01983917
- Testing
- Diabetes Mobile Application
- Where
- United States
- Sponsor
- University of California, Los Angeles
Urinary Incontinence, Cystocele
Enhanced Recovery Protocol in Urogynecologic Surgery
Enhanced recovery after surgery (ERAS) has been shown to improve postoperative outcomes in a variety of surgical conditions. However, data regarding its role in urogynecologic surgery is limited.
- Conditions
- Urinary Incontinence, Cystocele, Rectocele, Pelvic Organ Prolapse
- Trial name
- NCT04175782
- Testing
- Enhanced recovery after surgery (ERAS) protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Breast Cancer
ERAS in Autologous Breast Reconstruction: A Pilot RCT
Over 26,000 Canadian women are diagnosed with breast cancer each year and 1 in 3 patients undergo mastectomy. With an upward of 40% of breast cancer patients seeking post-mastectomy breast reconstruction (PMBR), there is a…
- Trial name
- ERAS-ABR (NCT04306003)
- Testing
- ERAS pathway, Standard Perioperative Care
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Hamilton Health Sciences Corporation
Multimorbidity
Enhanced Care for Patients With Complex Multimorbidity in Primary Care
Introduction Patients living with a chronic disease often have more than one chronic condition, which is referred to as multimorbidity.
- Trial name
- MM600-DK (NCT05676541)
- Testing
- Complex intervention to enhance care for patients with multimorbidity in general practice consisting of an extended overview consultation and supporting elements
- Where
- Denmark
- Volunteers
- 117,000 people
- Sponsor
- University of Copenhagen
Cognitive Impairment, Mild, Quality of Life
Virtual Reality Stimulation to Enhance Cognitive Function of Intensive Care Unit Patients
An observational study will be conducted in the ICU (Intensive care unit) including patients with heart surgery (< 5 days) and prolonged ICU stay (> 5 days). Patients will receive 5 min Virtual reality stimulation per day.
- Trial name
- NCT03025373
- Testing
- Visuo-acoustic stimulation
- Where
- Switzerland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Psychotic Disorders, ADHD
Cognitive Remediation in Forensic Mental Health Care
Forensic patients often display cognitive deficits, particularly in the domain of executive functions, that represent a challenge to forensic rehabilitation.
- Conditions
- Psychotic Disorders, ADHD, TBI (Traumatic Brain Injury), Aggression
- Trial name
- CRFMHC (NCT04610697)
- Testing
- Cognitive Remediation, Active Control
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Visual Rehabilitation, Visual Impairment, Autism Spectrum Disorder, Developmental Disabilities, Intellectual Disability, Behavioral Symptoms
Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs
The goal of this clinical trial is to learn about the effects of the structured program incorporating contextual, behavioral, and cognitive strategies to improve compliance of children and adolescents with special needs during…
- Trial name
- NCT06717282
- Testing
- visual rehabilitation for ophthalmic compliance, Using contextual, behavioral, and cognitive-based stragegies to develop training programs
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Parenting, Development
Primary Care-based Program to Enhance Positive Parenting Practices
The objective of this research is to conduct a small randomized pilot study to evaluate the feasibility of Sit Down and Play (SDP), a brief, low-cost program delivered in the primary care setting to enhance parent-child…
- Conditions
- Parenting, Development, Language, Children
- Trial name
- NCT02871973
- Testing
- Sit Down and Play, Handout
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Illinois Chicago
Prematurity
Coached, Coordinated, Enhanced Neonatal Transition (CCENT)
This study will evaluate a new neonatal follow-up model that offers additional support and coping resources for parents during their child's NICU admission as well as during their transition home.
- Trial name
- CCENT (NCT03350243)
- Testing
- CCENT Intervention
- Where
- 7 sites in Canada
- Volunteers
- 275 people
- Sponsor
- The Hospital for Sick Children
Psychosis, Schizophrenia
Enhanced Coordinated Specialty Care for Early Psychosis
The goal of this clinical trial is to compare engagement in treatment in coordinated specialty care (CSC) to five extra care elements (CSC 2.0) in first-episode psychosis.
- Conditions
- Psychosis, Schizophrenia, Schizoaffective Disorder, Psychosis Nos/Other
- Trial name
- NCT06071858
- Testing
- Care Coordination, Individual Peer Support, Digital Outreach
- Where
- 5 sites in United States
- Volunteers
- 350 people
- Sponsor
- Mclean Hospital
Coronary Artery Disease
An Internet-based Cardiac Rehabilitation Enhancement (i-CARE) Intervention to Support Self-care of Patients With Coronary Artery Disease
This study aims to examine the effects of an internet-based cardica rehabilitation enhancement (i-CARE) programme for coronary artery disease (CAD) patients on self-care behaviour, biomarkers, physiological, anthropometric…
- Trial name
- NCT04858503
- Testing
- internet-based cardiac rehabilitation enhancement intervention
- Where
- Hong Kong
- Volunteers
- 268 people
- Sponsor
- The University of Hong Kong
Dental Fear and Anxiety
Sensory Adapted Dental Environments to Enhance Oral Care for Children With and Without Dental Fear and Anxiety
This study is a randomized clinical trial investigating the effectiveness of a Sensory Adapted Dental Environment (SADE) alone and together with a video-based modeling (VBM) component (VBM-SADE), compared to a regular dental…
- Trial name
- SADE-DFA (NCT06912854)
- Testing
- Sensory Adapted Dental Environment, Video-based Modeling
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hormone Care, Mild Depression
Feasibility and Acceptability of Peer Intervention for Improving Mental Health Among People Accessing Hormone Care
The purpose of this study is to test whether the peer support program is acceptable, possible, and can improve mental health among individuals accessing hormone care.
- Conditions
- Hormone Care, Mild Depression, Anxiety
- Trial name
- NCT07354113
- Testing
- Peer support group, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Appointment Reminders
Using Behavioral Economics to Enhance Appointment Reminders and Reduce Missed Visits
"No-shows," or missed visits are a persistent problem in all health care systems. They contribute to worsened patient access, longer wait times, and inefficient use limited health care resources.
- Trial name
- No Show (NCT03850431)
- Testing
- Social Norms + Behavioral Instructions, Caring + Consequences for Others + Behavioral Instructions, Caring + Consequences for Self + Behavioral Instructions
- Where
- United States
- Volunteers
- 34,516 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hepatitis B
Evaluation of Hepatitis B Virus (HBV) DNA Test As Point of Care Tool
This is a cross sectional observational study to asses the performance of two novel HBV DNA testing methodologies; a) dried blood spot sampling and b) fingerstick capillary blood using the Xpert® Hepatitis B Virus viral load…
- Trial name
- HBVPOCT (NCT05144776)
- Testing
- GeneXpert HBV DNA Viral Load Assay, Dried Blood Spot HBV DNA test
- Where
- 6 sites in Australia
- Volunteers
- 268 people
- Sponsor
- Kirby Institute