Clinical trials: Enhanced Care
Septic Shock
Continuous Hemodialysis With an Enhanced Middle Molecule Clearance Membrane
This study aims to demonstrate equivalence in terms of molecule removal between continuous hemodialysis using an "enhanced middle molecule clearance" membrane(Ultraflux EMiC2) and continuous hemofiltration using a standard…
- Trial name
- NCT01067313
- Testing
- Dialyzer Ultraflux EMiC2, Dialyzer Ultraflux AV1000S
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Fresenius Medical Care France
Childhood Obesity
The Healthy Families Project
A primary care approach to obesity prevention will be developed and tested in a randomized trial in 4 pediatric primary care practices.
- Trial name
- HF (NCT01193374)
- Testing
- Clinician enhanced screening and counseling prompts, Tailored education and motivational materials, basic educational brochure
- Where
- 2 sites in United States
- Volunteers
- 149 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Colorectal Disorders
Fast-Track Colorectal Surgery in Senior Patients
Fast-track (FT) surgery is a multimodal, multidisciplinary-team approach to reduce perioperative surgical stress and injury after colorectal surgery, resulting in lower morbidity and enhanced recovery.
- Trial name
- FT-SS (NCT01646190)
- Testing
- Preoperative Carbohydrate load, individualized i.v fluids therapy, Fasting state after midnight
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University Hospital, Geneva
Type2diabetes, Enhanced Recovery After Surgery (ERAS)
Preoperative Carbohydrate Loading in Diabetes Mellitus
This prospective, randomized, open-label, parallel-group clinical trial aims to evaluate the safety and metabolic effects of preoperative carbohydrate loading in patients with well-controlled type 2 diabetes mellitus (T2DM)…
- Conditions
- Type2diabetes, Enhanced Recovery After Surgery (ERAS), Fasting, Carbohydrate Loading
- Trial name
- PRECARB-DMP (NCT07237841)
- Testing
- 25% Carbohydrate solution (CHO drinking)
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- Gia Dinh People Hospital
Transarterial Chemoembolization, TACE(Transcatheter Arterial Chemoembolization)
Effectiveness of Enhanced Web-Based Health Education on Self-Care Practices and Quality of Life Among Patients With Hepatocellular Carcinoma Undergoing TACE
This randomized controlled trial aims to evaluate the effectiveness of enhanced web-based health education on self-care practices and quality of life among patients with hepatocellular carcinoma.
- Conditions
- Transarterial Chemoembolization, TACE(Transcatheter Arterial Chemoembolization), Web-based Intervention, Quality of Life
- Trial name
- NCT07825519
- Testing
- Enhanced Web-Based Health Education, Routine Health Education
- Where
- Vietnam
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Adolescent Behavior, Psychosocial Functioning
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care.
- Conditions
- Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior
- Trial name
- NCT06019377
- Testing
- Stronger Youth Networks and Coping (SYNC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Portland State University
Aortic Valve Insufficiency, Aortic Stenosis
Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in Space
NASA has outlined the most urgent threats to life and health in manned spaceflight. One of the threats is the risk of trauma and acute medical problems.
- Trial name
- NCT00598767
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Opioid Use Disorder
Peer-led, Mobile App Supported Linkage to Opioid Use Disorder Treatment
This is the third phase of the mPeer4Life study - the Trial Phase, will be evaluating the intervention that was developed based on the Formative and Pilot Phases.
- Trial name
- mPeer4Life (NCT07900828)
- Testing
- Mobile phone-assisted intervention, Peer navigator, Standard of care referral for out-patient MAT
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Johns Hopkins University
Osteoarthritis
Tranexamic Acid in Knee Joint Surgery
Total knee joint replacement surgery can lead to significant blood loss, which can affect recovery after surgery. Tranexamic acid (TXA) is a medication which stops the breakdown of blood clots and therefore prevents blood loss.
- Trial name
- TRACKS (NCT02278263)
- Testing
- Tranexamic Acid, Normal saline (0.9% NaCl)
- Where
- 5 sites in New Zealand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Andrew G Hill, MBChB, MD (Thesis), EdD, FACS, FRACS
Medication Adherence, Self Management
Medication Adherence Enhancement in Heart Transplant Recipients
Medication-related non-adherence increases the risk of rejections and associated graft loss after solid organ transplantation. A randomized controlled intervention will use adherence enhancing strategies out of a larger sample of…
- Conditions
- Medication Adherence, Self Management, Rejection
- Trial name
- NCT00843960
- Testing
- behavioral adaptation and symptom management
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Hannover Medical School
Critically Ill, Malnutrition
Promotion of Oesophageal Motility to Prevent Regurgitation and Enhance Nutrition Intake in ICU Patients.
Early enteral feeding is a key component of the management of critically ill patients receiving mechanical ventilation. However, enteral feeding has been associated with serious complications such as gastro-esophageal reflux…
- Trial name
- PROPEL (NCT02515123)
- Testing
- E-Motion System
- Where
- 11 sites in Canada
- Volunteers
- 158 people
- Sponsor
- E-Motion Medical Ltd.
Autism
Sensory Adapted Dental Environment to Enhance Oral Care for Children With ASD
The goal of this project is to collect information that will support a later clinical trial on the effectiveness of a specially adapted dental environment for children who have difficulty tolerating oral care in the dental…
- Trial name
- SADE (NCT02077985)
- Testing
- Sensory Adapted Dental Environment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Out-of-hospital Cardiac Arrest (OHCA)
Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care
Out-of-hospital cardiac arrest (OHCA) remains a leading global emergency condition with low survival to hospital discharge despite advances in cardiopulmonary resuscitation.
- Trial name
- RE-ARREST (NCT07239908)
- Testing
- Prehospital post cardiac arrest care protocol
- Where
- Thailand
- Volunteers
- 318 people
- Sponsor
- Siriraj Hospital
Perioperative Care, Postoperative Complications
Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol in Gastric Surgery for Cancer
Methods National audit of a 90-day prospective observational cohort in which postoperative complications will be analyzed at 30 days of follow-up in adult patients undergoing scheduled surgery for gastric resection for cancer…
- Conditions
- Perioperative Care, Postoperative Complications, Gastric Cancer
- Trial name
- POWER4 (NCT03865810)
- Where
- 66 sites in Spain
- Volunteers
- 861 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Staff Attitude
Enhanced Care Home Outcomes: A Qualitative Study
This qualitative study uses focus group methodology and purposive sampling with the aim of obtaining views of Care Home Support Service staff and other stakeholders about their experiences of a redesigned National Health Service…
- Trial name
- ECHO (NCT02703792)
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Oxford Health NHS Foundation Trust
Lung Cancer, Lung Neoplasms/Diagnosis
The MyLungHealth Study Protocol: Engaging Patients to Enable Interoperable Lung Cancer Decision Support at Scale
Early lung cancer screening (LCS) through low-dose computed tomography (LDCT) is crucial but underused due to various barriers, including incomplete or inaccurate patient smoking data in the electronic health record and limited…
- Trial name
- MyLungHealth (NCT06338592)
- Testing
- MyLungHealth, DecisionPrecision+
- Where
- 2 sites in United States
- Volunteers
- 31,303 people
- Sponsor
- University of Utah
Asthma
Redesigning Ambulatory Care Delivery to Enhance Asthma Control in Children
The investigators have developed a tool to facilitate asthma self-management in children, the electronic-AsthmaTracker (e-AT). The e-AT changes ambulatory asthma care delivery to a new model that is continuous and proactive…
- Trial name
- NCT02409277
- Testing
- Experimental: Standard vs Intensive e-AT Intervention
- Where
- United States
- Volunteers
- 926 people, healthy volunteers welcome
- Sponsor
- University of Utah
Overweight, Obesity
Enhanced Primary Care and Technology for Children With Chronic Disease
Using technology alongside a pediatric chronic disease specialist and behavior specialist, the investigators are planning to help care for and coordinate the healthcare of children with chronic diseases, particularly childhood…
- Conditions
- Overweight, Obesity, Asthma
- Trial name
- NCT02490566
- Testing
- Telehealth
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Miami
Skin Quality Improvement
Enhanced Photoaging Reversal Efficacy and Safety of 755nm Alexandrite Picosecond Laser with Diffractive Lens Array (DLA) in Conjunction with Integrated Skin Care for Skin Quality Improvement
This study evaluates enhanced photoaging reversal efficacy and safety of 755nm alexandrite picosecond laser with diffractive lens array (DLA) in conjunction with integrated skin care for skin quality improvement.
- Trial name
- NCT06818630
- Testing
- SkinCeuticals combination skin care products, Regular skin care procedure
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- L'Oréal Taiwan Co., Ltd
Premature Birth
Family Nurture Intervention (FNI) in Neonatal Intensive Care Unit (NICU)
The purpose of this study is to test the efficacy of a family nurture intervention in the neonatal intensive care unit (NICU). Infants receiving enhanced mother-infant and family nurture are compared to infants receiving standard…
- Trial name
- NCT01439269
- Testing
- Family Nurture Intervention
- Where
- United States
- Volunteers
- 394 people
- Sponsor
- Columbia University