Clinical trials: Enteral Feeding Intolerance, active
Enteral Nutrition, Enteral Nutrition Feeding
Stepwise Enteral Nutritional Algorithm and Patient Outcomes in Pediatric Intensive Care Units
The aim of the study to evaluate the effectiveness and patient's outcome after implementing enteral nutrition algorithm designed to achieve optimal enteral nutrition delivery in the pediatric intensive care unit and to evaluate…
- Conditions
- Enteral Nutrition, Enteral Nutrition Feeding, Enteral Nutrition Intolerance in Critically Ill Patients
- Trial name
- NCT07307027
- Testing
- Stepwise Enteral Nutritional Algorithm
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Enteral Feeding Intolerance, Critical Illness
Continuous Versus Intermittent Enteral Feeding and Gastric Residual Volume in Critically Ill Patients
This study will compare two commonly used methods of enteral feeding in critically ill adults: continuous feeding and intermittent feeding.
- Trial name
- NCT07876141
- Testing
- Continuous Enteral Feeding, Intermittent Enteral Feeding
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- Viet Duc University Hospital
Enteral Feeding Intolerance
Bedside Observation by Clinical Ultrasound for Stomach Expansion
The objective of the BOCUSE study is to demonstrate a relationship between an early ultrasound measurement of the gastric antral area and the subsequent occurrence of poor gastric tolerance.
- Trial name
- BOCUSE (NCT07312890)
- Testing
- Gastric ultrasound with measurement of the antral area
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Amyotrophic Lateral Sclerosis, Gastrointestinal Intolerance
Oral Intake of Enteral Nutrition Formula Preceding Placement and Feeding Via GTube and Its Impact on Formula Intolerance in pALS
The main objective of the proposed study is to evaluate if oral intake of EN formula preceding Gtube placement will impact tolerance upon placement and feeding via Gtube in pALS.
- Conditions
- Amyotrophic Lateral Sclerosis, Gastrointestinal Intolerance, Enteral Nutrition Therapy
- Trial name
- NCT06609213
- Testing
- Medical Food
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Andrea Charvet
Acute Pancreatitis (AP), Enhancing Enteral Nutrition Tolerance
Evaluating RELiZORB Use for the Treatment of Feeding Intolerance in Adults With Moderate to Severe Acute Pancreatitis
The goal of this study is to learn if Relizorb, a fat-digesting enzyme, can improve tolerance of tube feeds in adult patients with moderate to severe pancreatitis.
- Trial name
- NCT07583342
- Testing
- RELiZORB digestive enzyme (immobilized lipase) cartridge
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Northwell Health
Gastroparesis, Shock
Gastric Emptying and Enteral Nutrition Tolerance According to Vasopressor Dose in ICU Patients
This study investigates whether the dose of vasopressor medications (drugs that maintain blood pressure in shock) affects gastric emptying during tube feeding in the intensive care unit (ICU).
- Conditions
- Gastroparesis, Shock, Critical Illness, Gastric Emptying
- Trial name
- NCT07802379
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Critical Illness, Gastro Intestinal Surgery
Undiluted and Diluted Nutrition
Adult patients after elective major abdominal surgeries who are planned to be admitted to the Intensive Care Unit (ICU) can be included in the trial. Each patient will be fed via the gastrointestinal tract.
- Conditions
- Critical Illness, Gastro Intestinal Surgery, Enteral Feeding Intolerance, Gastro-Intestinal Disorder
- Trial name
- NCT07352150
- Testing
- Enteral fluid, Intravenous fluid
- Where
- 2 sites in Poland
- Volunteers
- 80 people
- Sponsor
- John Paul II Catholic University of Lublin
Traumatic Brain Injury, Neurocritical Care
Effect of Semi-elemental Enteral Nutrition on Gastrointestinal Tolerance in Patients With Traumatic Brain Injury.
Study Objective This clinical trial primarily aims to investigate whether semi-elemental enteral nutrition (SEN) improves gastrointestinal tolerance in patients with severe traumatic brain injury (TBI) and to evaluate its impact…
- Conditions
- Traumatic Brain Injury, Neurocritical Care, Enteral Feeding Intolerance
- Trial name
- SEMINAR (NCT07092423)
- Testing
- Semi-elemental formula, Standard formula
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tang-Du Hospital
Patients Who Receive Enteral Nutrition for at Least 72 Hours in the Intensive Care Unit Will be Included in the Study
FACTORS AFFECTİNG ENTERAL FEEDİNG INTOLERANCE İN INTENSİVE CARE UNİT PATİENTS
Enteral nutrition is the first-line nutritional support method in critically ill patients because it helps preserve gastrointestinal system integrity, reduce the risk of infection, and meet metabolic requirements.
- Trial name
- EFI-ICU (NCT07780734)
- Volunteers
- 102 people
- Sponsor
- Eda Cirit Bardakçi
Prematurity, Light-For-Dates
Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants
In this proposed clinical trial, the investigators will randomize 80 very preterm (VPT) infants to receive either early (between day 4 and 7) or delayed (between day 10 and 14) fortification and determine if providing early…
- Conditions
- Prematurity, Light-For-Dates, Enteral Feeding Intolerance
- Trial name
- ENACT+ (NCT05525585)
- Testing
- Early HMF, Delayed HMF
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Septic Shock
Splanchnic Perfusion Monitoring in Septic Shock Using Doppler Ultrasound
evaluation whether splanchnic Doppler ultrasound indices (SMA resistive index, portal vein pulsatility fraction, hepatic artery resistive index/flow parameters) can: 1.
- Trial name
- NCT07698834
- Volunteers
- 80 people
- Sponsor
- Assiut University
Enteral Feeding Intolerance
A Comparative Evaluation of Mosapride Versus Metoclopramide for Enteral Feeding Intolerance in Critically Ill Patients
Caring for critically ill patients in an intensive care unit (ICU) is considered a standard of care. According to the Society of Critical Care Medicine (SCCM), as a function of the complex nature of the care provided in the ICU…
- Trial name
- NCT06826443
- Testing
- Mosapride Citrate Tablets, Metoclopramide 10mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Feeding Patterns, Sleep
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic…
- Conditions
- Feeding Patterns, Sleep, Glucose Intolerance
- Trial name
- NCT04737200
- Testing
- Time-of-day of enteral nutrition provision (daytime first), Time-of-day of enteral nutrition provision (nighttime first)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Feeding Intolerance
Efficacy of Itopride Versus Metoclopramide in Hospitalized Medicine Patients With High Gastric Residual Volume
A prospective randomized controlled trial included 86 patients in medicine ward who were diagnosed with feeding intolerance, defined as having a gastric residual volume greater than 200 ml.
- Trial name
- GRV (NCT07031479)
- Testing
- Itopride HCI 50 mg, Metoclopramide 10 mg ampoule
- Volunteers
- 86 people
- Sponsor
- Chulalongkorn University
Feeding, ICU
mNEED: a Multicentre, Cluster-randomized, Controlled Trial
Project Name: Improved Feeding Regimen for Critically Ill Patients (mNEED) Based on Feeding Intolerance Prediction Model Solution version number and version date: Version 5.0; 2024.12.16 Informed consent version number and…
- Trial name
- mNEED (NCT06827275)
- Testing
- Feeding process
- Where
- 2 sites in China
- Volunteers
- 2,250 people
- Sponsor
- The First Hospital of Jilin University
Enteral Feeding Intolerance
Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology
Blenderized diets consist of a wide range of table foods such as fruits, vegetables, meat and legumes, pureed in a blender and administered via gastrostomy tube.
- Trial name
- NCT04900597
- Testing
- Elecare Jr, Nourish, Real Foods Blends
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston Children's Hospital
Critically Ill Patients Who Are Not Allowed to Eat Orally But Can Initiate Enteral Nutrition Within 48 Hours of ICU
Association of Biomarkers and Gastric Antral Motility Index With Feeding Intolerance in Critically Ill Patients
When the subjects are admitted to the department, the researchers will monitor potential biomarkers of gastrointestinal injury before administering enteral nutrition (a small amount of blood is drawn, serum is separated by…
- Trial name
- NCT07178626
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First Hospital of Jilin University
Critical Illness, Enteral Nutrition Intolerance
Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients
This study aims to explore the correlation between gastrointestinal blood flow and the incidence of enteral nutrition intolerance (ENI) and its symptoms in critically ill patients, construct and compare predictive models…
- Conditions
- Critical Illness, Enteral Nutrition Intolerance, Enteral Nutrition Feeding, Prediction Models
- Trial name
- NCT07521111
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Critical Illness, Organ Dysfunction
The Effect of the Timing of Supplemental Parenteral Nutrition on the Prognosis of Critically Ill Patients (T-SPN)
This multicenter, randomized controlled trial aims to evaluate whether early initiation of supplemental parenteral nutrition (SPN) (on day 4 of ICU admission) compared to late initiation (on day 8) can reduce 28-day all-cause…
- Conditions
- Critical Illness, Organ Dysfunction, Enteral Nutrition Intolerance, Inadequate Nutritional Intake
- Trial name
- NCT07085455
- Testing
- Early Supplemental Parenteral Nutrition (SPN), Late Supplemental Parenteral Nutrition (SPN)
- Where
- 2 sites in China
- Volunteers
- 946 people
- Sponsor
- Dong Zhang
Refractory Enteral Feeding Intolerance, Gut Microbiota
Gut Microbiota Structure, Functional and Metabolic Profiles, and Composite Biomarkers in ICU Adults With Refractory Enteral Feeding Intolerance
Some adults in the intensive care unit (ICU) cannot receive enough nutrition through a feeding tube because of persistent digestive problems, even after standard measures to improve feeding.
- Conditions
- Refractory Enteral Feeding Intolerance, Gut Microbiota, Metabolic Profiles
- Trial name
- NCT07864844
- Testing
- Naturally Occurring Exposures
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology