Clinical trials: Enteral Nutrition Feeding
Feeding; Difficult, Newborn, Growth Failure
Prophylactic Probiotics to Extremely Low Birth Weight Prematures
Mortality and incidence of severe complications is still high among extremely premature infants. Common causes of severe complications in this population are poor nutrition, necrotizing enterocolitis, and severe infections.
- Conditions
- Feeding; Difficult, Newborn, Growth Failure, Necrotizing Enterocolitis, Sepsis
- Trial name
- PROPEL (NCT01603368)
- Testing
- Lactobacillus reuteri
- Where
- 2 sites in Sweden
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Ostergotland County Council, Sweden
Nutrition, Enteral
A More Physiological Feeding Process in ICU:the Intermittent Infusion With Semi-solidification of Nutrients
Malnutrition and underfeeding are major challenges in caring for critically ill patients. Continuous feeding were thought to be better tolerated by patients with the limited absorptive gut surface area or gastrointestinal…
- Trial name
- NCT03017079
- Testing
- semi-solid agent with standard enteral feeding, standard enteral feeding
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Critically Ill
Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients
Critically ill patients are consistently underfed. Feeding protocols are standardized system tools used to guide nutrition practices, but to date have failed to improve delivery of nutrition.
- Trial name
- PEPuP (NCT01167595)
- Testing
- PEP uP Protocol
- Where
- 18 sites in United States, Canada
- Volunteers
- 1,059 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Critically Ill
PEP uP Protocol in Surgical Patients
The main objective of this project is to asses for safety, feasibility and effectiveness of an aggressive feeding protocol, PEP uP (Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol) in increasing protein…
- Trial name
- NCT02459275
- Testing
- PEP uP Protocol, Metoclopramide
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Enteral Feeding Intolerance
Optimal Feeding Tube Placement
A randomized controlled trial comparing current standard blind method to CORTRAK enteral access system (CEAS), an FDA approved electromagnetic device to place enteric tubes.
- Trial name
- NCT04241146
- Testing
- Enteric Tube, CORTRAK enteral access system
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Preterm Birth, Tube Feeding
Maternal Role in Oral Feed Establishment in Preterm Neonates
Hypothesis Preterm babies who receive sensory motor stimulation from their mothers as compared to trained nurses will 1. Start taking oral feed at the same time as compared to control group 2.
- Conditions
- Preterm Birth, Tube Feeding, Swallowing Disorder, Maternal Care Patterns
- Trial name
- NCT05484726
- Testing
- perioral sensory motor stimulation
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Exocrine Pancreatic Insufficiency
Safety, Tolerability and Fat Absorption Using Enteral Feeding In-line Enzyme Cartridge (Relizorb)
Protocol ALCT-0000497 is a multicenter safety, tolerability and fat absorption study that anticipates enrolling 35 male and female subjects (pediatric and adult) with cystic fibrosis.
- Trial name
- NCT02598128
- Testing
- RELiZORB
- Where
- 11 sites in United States
- Volunteers
- 34 people
- Sponsor
- Alcresta Therapeutics, Inc.
Enteral Feeding Intolerance
A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance
This study is being conducted to evaluate the safety, tolerability and early efficacy of IV TD 8954 compared to metoclopramide in critically ill subjects, aged 18 to 85 years, who are admitted to the intensive care require…
- Trial name
- NCT01953081
- Testing
- TD-8954, Metoclopramide
- Where
- Australia
- Volunteers
- 13 people
- Sponsor
- Takeda
Enteral Feeding
Studying the Influence of Exposure to Maternal Voice on Oral Feeding Volumes in Preterm Infants
Oral feeding is one of the primary functions of the neonatal brain. In preterm infant population, competency at oral feeding is one of the major milestones in preparation for discharge.
- Trial name
- NCT05181020
- Testing
- Maternal Voice Exposure
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Connecticut Children's Medical Center
Enteral Nutrition
TubeClear® Evaluation in Pediatric Patients (Phase I)
This is the first of three planned phases designed to evaluate the feasibility and tolerability of TubeClear® to restore patency in occluded Pediatric Enteral Access Devices.
- Trial name
- NCT02724631
- Testing
- TubeClear® intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Children's Hospital of Philadelphia
Ventilation-Associated Pneumonia
Study of Impact of Not Measuring Residual Gastric Volume on Nosocomial Pneumonia Rates
Early enteral feeding is a key component of the management of critically ill patients receiving mechanical ventilation. However, enteral feeding has been associated with serious complications such as aspiration followed by…
- Trial name
- NUTRIREA1 (NCT01137487)
- Testing
- monitoring of residual gastric volume, not monitoring of residual gastric volume
- Where
- 6 sites in France
- Volunteers
- 452 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Critical Illness
The Energy Dose Study
The investigators have designed this single-center Randomized Clinical Trial (RCT) to prospectively compare, for the first time, the clinical efficacy of different energy doses in intensive care unit (ICU) patients requiring…
- Trial name
- NCT01369147
- Testing
- Parenteral Nutrition, Propofol, Clevidipine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Emory University
Enteral Nutrition
DrIFT 2 Study: Displacement in Feeding Tubes
The proposed study will use an electromagnetic placement device (EMPD), Cortrak* 2 Enteral Access System (EAS™), Avanos Medical, to verify feeding tube (FT) position on a daily basis to assess for migration.
- Trial name
- NCT06239610
- Testing
- electromagnetic placement device
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Parkview Health
Critical Illness, Enteral Nutrition
TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)
The purpose of this study is to assess the treatment effect of intravenous TAK-954 in improving the average daily protein adequacy received through enteral nutrition in critically-ill participants developing EFI.
- Conditions
- Critical Illness, Enteral Nutrition, Enteral Feeding Intolerance
- Trial name
- NCT03477903
- Testing
- TAK-954, Metoclopramide, Normal Saline
- Where
- 44 sites in United States, Australia and 2 more
- Volunteers
- 1 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Acute Lung Injury
Intensive Nutrition in Acute Respiratory Distress Syndrome (ARDS): A Clinical Trial (INTACT)
The investigators propose a prospective randomized clinical trail to evaluate the impact of intensive medical nutrition therapy (IMNT) in patients with acute respiratory distress syndrome (ARDS) or acute lung injury (ALI) on…
- Trial name
- INTACT (NCT01921101)
- Testing
- intensive medical nutrition, control
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Illinois Chicago
Type 2 Diabetes
Evaluation of White Sweet Potato Tube Feeding Formula on Type 2 Diabetic Residents in Long-term Care Institutions
In order to response the increasing of aging population cause losing ability that need long-care needs, the project entitled "10-year long-term care program" from Executive Yuan in 2007 is carried out to assist economically…
- Trial name
- NCT02711839
- Testing
- Commercial diabetic formula, White sweet potato formula
- Volunteers
- 54 people
- Sponsor
- Taipei Medical University
Feeding Tube Complication
Safety and Efficacy of Enteral Feeding Tube Stoma Site Accessory
The purpose of the study is to collect safety and efficacy data on the performance of the study stoma site accessory when used to prevent abdominal wall leakage for patients with a long term feeding tube.
- Trial name
- SSA (NCT05288556)
- Testing
- Placement of stoma site enteral feeding tube accessory
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Eric Yudelevich
Cystic Fibrosis
Absorption and Safety With Sustained Use of RELiZORB Evaluation (ASSURE) Study
Protocol 0000498: Multicenter, open label study to evaluate the effect of sustained RELiZORB (immobilized lipase) cartridge use during enteral feeding on fat absorption, as well as safety and tolerability of sustained RELiZORB…
- Trial name
- ASSURE (NCT02750501)
- Testing
- RELiZORB (immobilized lipase) cartridge, Impact Peptide 1.5
- Where
- 10 sites in United States
- Volunteers
- 49 people
- Sponsor
- Alcresta Therapeutics, Inc.
Enteral Feeding in Bronchiolitis
Comparison Between Gastric and Post Pyloric Tube Feedings in Children With Bronchiolitis Requiring High Flow Nasal Cannula
The purpose of the study is to compare two ways (nasogastric tube (NGT) and nasoduodenal tube (NDT)) to provide nutrition to infants admitted to the hospital for viral bronchiolitis and who require high flow nasal cannula therapy.
- Trial name
- NCT03346850
- Testing
- Nasogastric tube (NGT) feeding, Nasoduodenal tube (NDT) feeding
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Enteral Feeding
Safety and Effectiveness of A Novel Enteral Feeding System: Prospective Study.
The goal of this interventional study is to obtain information on the safety and effectiveness of a novel enteral feeding system in adult users requiring at least a portion of their nutritional intake via enteral feeding.
- Trial name
- NCT06173063
- Testing
- Mobility+ Enteral Feeding System
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Rockfield Medical Devices