Clinical trials: Environment, open to volunteers
Cerebral Palsy (CP), Motor Disability
Complex Rehabilitation Technology Enabled Physical Activity for Children With Motor Delays Via Telehealth in Natural Environments
The primary goal of CP-MOVES is to evaluate 1) the preliminary efficacy of a telehealth-delivered, parent coaching intervention in the use of adaptive standers, on physical activity, sleep, and endurance in young children with…
- Conditions
- Cerebral Palsy (CP), Motor Disability, Motor Delay
- Trial name
- CP-MOVES (NCT07252713)
- Testing
- Stander Use
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University
Hospitalism
Immersive Sensory Projections for Hospitalized Patients
The purpose of this study is to assess the impact of adding three sensory elements (visual, auditory, olfactory) on reducing discomfort in patients hospitalized in the intensive care unit/continuing care unit.
- Trial name
- IHP (NCT06577870)
- Testing
- Hospitalization in intensive care or continuing care unit
- Where
- France
- Volunteers
- 208 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pancreatic Cancer
Pancreatic Cancer Lifestyle Evolution And Resistance
Advanced PDAC patients undergo polychemotherapy, yet responses are highly variable. Transcriptome signatures are emerging as key predictors of treatment response. However, PDAC adapts across sites (primary vs.
- Trial name
- CLEAR (NCT07794969)
- Testing
- Endoscopic Ultrasound with FNA/FNB
- Volunteers
- 150 people
- Sponsor
- IRCCS San Raffaele
Pregnancy, Primiparous Women
Maternal Reflective Functioning During the Transition to Motherhood
The goal of this clinical trial is to learn about Maternal Reflective Function (MRF) during the transition to motherhood. The main questions it aims to answer are: Does MRF mediates the connection between risk factors for mental…
- Trial name
- NCT06476626
- Testing
- Maternal Reflective Function Workshop
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Bipolar Disorder, Schizophrenia
Immuno-Genetic, Inflammation, Retro-Virus, Environment
Immunology combined to neurobiology now offer prominent tools to yield biomarkers, so far missing in psychiatry, and to design innovative treatment approaches based on the discovery of new molecular and cellular targets.
- Trial name
- I-Give (NCT02878408)
- Testing
- Blood sampling
- Where
- 6 sites in France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Pr. Marion Leboyer
Work of Breathing
The Role of Breathing Perception in Respiratory Control
Warfighters are frequently exposed to environments and life-support systems that increase breathing resistance and the work of breathing (WOB), such as aircraft on-board oxygen generation systems and underwater breathing…
- Trial name
- NCT07470099
- Testing
- Ambient Noise, Increased Auditory Feedback, Noise Distraction
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Indiana University
Environmental Sustainability in Radiology, Iodinated Contrast Agent Recovery
GREENWATER 2.0: Reducing Iodinated Contrast Agents in Hospital Wastewater
The goal of this observational study is to learn if using a dedicated urine collection device after CT scans can help reduce the amount of iodinated contrast agent released into hospital wastewater in adult outpatients undergoing…
- Trial name
- GREENWATER 2 (NCT07620093)
- Testing
- Dedicated Urine Collection Device (Toilet)
- Where
- Italy
- Volunteers
- 416 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Oral Feeding Outcomes, Neurodevelopment Outcome
Impact of Hospital to Home: Optimizing Preterm Infant Environment for Surgical Neonates and Their Parents (H-HOPE)
Infants born with congenital defects may require major surgery in the neonatal period. These infants are at risk for neurodevelopmental impairments.
- Trial name
- H-HOPE (NCT07372898)
- Testing
- H-HOPE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Child Development, Adaptive Behavior
Effects of Music and Storytelling on Linguistic, Socioemotional, and Adaptive Development in Children Aged 12-36 Months: an Intervention Protocol in Municipal Early Childhood Centers
This randomized clinical trial aims to evaluate the impact of a structured enriched environment on the linguistic, adaptive behavior, and socioemotional development of children aged 12 to 36 months.
- Conditions
- Child Development, Adaptive Behavior, Early Child Development, Music Education
- Trial name
- MUS-STORY (NCT06831851)
- Testing
- Storytelling Sessions, Music Education Sessions, Parental Guidance Sessions
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Actinic Keratosis, Imipramine
The Effect of Topical Imipramine on Photodynamic Therapy-Mediated Immunosuppression on Forearms or Face on US Veterans
The purpose of this study is to test the use of topical imipramine in combination with topical photodynamic therapy's (PDT) effect on the effectiveness and pain immunosuppression following treatment.
- Conditions
- Actinic Keratosis, Imipramine, Photodynamic Therapy
- Trial name
- NCT06778434
- Testing
- Imipramine, Control Vehicle
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Stress (Psychology), Environment
Stress Through Audition: Uptake, Recovery, Oscillations During Nature Exposure
The protocol the investigators propose aims to address certain gaps by developing a multimodal paradigm, based on: Induction of acute stress via the Maastricht Acute Stress Test (MAST), a standardised protocol recognised for its…
- Trial name
- SAURON (NCT07857239)
- Testing
- Natural soundscape auditory exposure, Urban soundscape auditory exposure
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Clinical Practice, Virtual Reality
The Effect of the Operating Room Environment on Patients Experienced With Virtual Reality Glasses Before Surgery
This study was planned as a randomized controlled experimental study with a pretest-posttest design to examine the effect of the operating room environment experience of preoperative patients using virtual reality glasses on the…
- Conditions
- Clinical Practice, Virtual Reality, Nursing Care, Simulation
- Trial name
- NCT06666465
- Testing
- Operating Room Environment Experienced by Patients Wearing Virtual Reality Glasses Before Surgery The Effect of Surgery Experience on Surgical Fear Level and Care Perceptions
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Hypertension, Aldosteronemia
Decode the Environment Variation of Targeted Aldosterone Inducer and siLencer
Clinical outcome to identify and analyze the epigenetic, phenotypic, protein variation, metabolites of CYP450 Family 11 Subfamily B, both 1 and 2, human-associated aldosterone protein release, and signaling inhibitory pathways…
- Conditions
- Hypertension, Aldosteronemia, CYP11B1, CYP11B2
- Trial name
- DETAIL (NCT07748975)
- Testing
- Aldosterone circulation, Medication, Operation
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- DejthidaNathaphong
Cancer, Cancer Comorbidities
The Cancer Stage Shifting Initiative: Registry and Biorepository to Research and Address Health Disparities in Cancer Care
The goal of this observational study is to establish a patient registry and a biorepository (sample collection and storage) to investigate health disparities, access, and barriers to cancer screening and early detection…
- Trial name
- CSSI (NCT07461493)
- Where
- 2 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- National Minority Quality Forum
Healthy Lifestyle
SENior PRIorat: Participatory Research for the Improvement of Lifestyles, Quality of Life, Emotional Well-being, and Locomotor Abilities of Older Adults in the Priorat
Spain is experiencing a demographic shift towards an ageing population. In 2022, 20.1% of Spaniards were 65 or older, a figure projected to reach 30.4% by 2050.
- Trial name
- SENPRI (NCT07189533)
- Testing
- Co-created intervention
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Prostate Cancer, Leukemia
Natural History Study of Early Life Exposures in Agriculture (ELEA)
Study Description: ELEA is an observational cohort study that will collect exposure information and biospecimens from the adult children of the Agricultural Health Study (AHS) cohort (https://aghealth.nih.gov/about; Protocol…
- Conditions
- Prostate Cancer, Leukemia, Breast Cancer, Melanoma
- Trial name
- NCT07328516
- Where
- United States
- Volunteers
- 64,277 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Cochlear Implant Users
Assessment of a Method to Improve Cochlear Implant Users' Speech Perception in Noisy Environments While Maintaining Their Ability to Determine Where a Sound Originates From
The goal of this clinical trial is to determine if a new algorithm can improve speech perception for cochlear implant users. The main questions it aims to answer [is/are]: Does the algorithm improve speech perception in noisy…
- Trial name
- NCT07323862
- Testing
- Modifying audio input for cochlear implant processor
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Illinois at Urbana-Champaign
Breast Cancer Prevention
MELIORA Data Collection Campaigns
To support the development of the MELIORA digital app for the MELIORA main intervention, an initial pilot study (Data Collection Campaign, DCC) is being conducted with the three target participant groups: healthy women at…
- Trial name
- DCC (NCT07190066)
- Testing
- Data Collection campaign
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Physical Activity Attitude, Health Behavior
Trust in Institutions, Environment, and Physical Activity
Trust is the willingness of people to cooperate. Although much research has been conducted on physical activity, little research has explored trust in institutions regarding environmental and physical activity recommendations.
- Conditions
- Physical Activity Attitude, Health Behavior, Trust
- Trial name
- TrustAndMove (NCT07472569)
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand